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Search results 101 to 192 out of 192 for Lbp

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Type Details Score
Publication
16439470 | J:111092
First Author: Isayama F
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: LPS signaling enhances hepatic fibrogenesis caused by experimental cholestasis in mice.
Volume: 290
Issue: 6
Pages: G1318-28
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Publication
24380872 | J:222669
First Author: Tanimura N
Year: 2014
Journal: Int Immunol
Title: The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane.
Volume: 26
Issue: 6
Pages: 307-14
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Publication
10047547 | J:53151
First Author: Ulevitch RJ
Year: 1999
Journal: Curr Opin Immunol
Title: Recognition of gram-negative bacteria and endotoxin by the innate immune system.
Volume: 11
Issue: 1
Pages: 19-22
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Publication
21787333 | J:174122
First Author: Bingle CD
Year: 2011
Journal: Biochem Soc Trans
Title: Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily.
Volume: 39
Issue: 4
Pages: 977-83
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Publication
26431947 | J:233770
First Author: Maxwell JR
Year: 2015
Journal: Immunity
Title: Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation.
Volume: 43
Issue: 4
Pages: 739-50
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Publication
38348657 | J:361183
First Author: Chen J
Year: 2024
Journal: Circ Res
Title: Molecular and Spatial Signatures of Mouse Embryonic Endothelial Cells at Single-Cell Resolution.
Volume: 134
Issue: 5
Pages: 529-546
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Publication
15769905 | J:99312
First Author: Jerez-Timaure NC
Year: 2005
Journal: Physiol Genomics
Title: Fine mapping of a QTL region with large effects on growth and fatness on mouse chromosome 2.
Volume: 21
Issue: 3
Pages: 411-22
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Publication
- | J:342596
       
First Author: GO Annotation working group
Year: 2023
Title: Manual annotations that require more than one source of functional data to support the assignment of the associated GO term
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Publication
21308778 | J:233117
First Author: Saeed H
Year: 2011
Journal: J Bone Miner Res
Title: Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.
Volume: 26
Issue: 7
Pages: 1494-505
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Lbp<tm1Jack> | MGI:1857976
Name: lipopolysaccharide binding protein; targeted mutation 1, Robert S Jack
Allele Type: Targeted
Attribute String: Null/knockout
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Author
Dos Santos LBP
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Publication
9695742 | J:49914
First Author: Wang SC
Year: 1998
Journal: J Surg Res
Title: Tissue coexpression of LBP and CD14 mRNA in a mouse model of sepsis.
Volume: 76
Issue: 1
Pages: 67-73
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Pathway
R-MMU-166020 | Transfer of LPS from LBP carrier to CD14
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Publication
15471945 | -
First Author: Huang N
Year: 2005
Journal: Mol Endocrinol
Title: LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells.
Volume: 19
Issue: 2
Pages: 409-20
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Publication
33069692 | J:309894
 
First Author: Pedroso JAB
Year: 2021
Journal: Peptides
Title: Deletion of growth hormone receptor in hypothalamic neurons affects the adaptation capacity to aerobic exercise.
Volume: 135
Pages: 170426
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Protein Domain
IPR030675 | BPI/LBP
Type: Family
Description: This entry represents the bactericidal permeability-increasing protein (BPI) and the lipopolysaccharide-binding protein (LBP). The crystal structures of BPI and LBP are similar [], and they may represent a common gene family of lipid-binding proteins [].In mammals, LBP and BPI mediate the biological effects of LPS (lipopolysaccharide), a glycolipid present in the outer membrane of Gram-negative bacteria. LBP is a plasma protein that enhances the inflammatory response to LPS, whereas BPI is found in lysosomal granules of polymorphonuclear neutrophils, is bactericidal, and neutralises the toxic effects of LPS [, ]. LBP is an acute phase serum protein secreted mainly by the liver that modulates the LPS-induced immune response. LBP binds mainly to the lipid A moiety of LPS and acts as an affinity enhancer for CD14, facilitating its association with LPS [].
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Strain
MGI:2450730 | C.129P2-Lbp<tm1Jack>/J
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Lbp/Lbp
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: hm
Has Mutant Allele: true
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Publication
7613727 | -
First Author: Elsbach P
Year: 1995
Journal: Infect Agents Dis
Title: Prospects for use of recombinant BPI in the treatment of gram-negative bacterial infections.
Volume: 4
Issue: 2
Pages: 102-9
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Publication
7517398 | -
First Author: Wilde CG
Year: 1994
Journal: J Biol Chem
Title: Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS-mediated cell activation.
Volume: 269
Issue: 26
Pages: 17411-6
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Publication
9441745 | -
First Author: Kirschning CJ
Year: 1997
Journal: Genomics
Title: Similar organization of the lipopolysaccharide-binding protein (LBP) and phospholipid transfer protein (PLTP) genes suggests a common gene family of lipid-binding proteins.
Volume: 46
Issue: 3
Pages: 416-25
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Protein Domain
IPR030181 | BPI
Type: Family
Description: Bactericidal/permeability-increasing protein (BPI) is a potent antimicrobial protein that binds to and neutralises lipopolysaccharide (LPS), a glycolipid present in the outer membrane of Gram-negative bacteria [].In mammals, two related LPS-binding proteins mediate the biological effects of LPS: LPS-binding protein (LBP) and BPI. LBP is a plasma protein that enhances the inflammatory response to LPS, whereas BPI is found in lysosomal granules of polymorphonuclear neutrophils, is bactericidal, and neutralises the toxic effects of LPS []. BPI belongs to the lipid transfer/lipopolysaccharide binding protein (LT/LBP) family, with LBP, the cholesteryl ester transfer protein (CETP) and the phospholipid transfer protein (PLTP) [].This entry represents mammalian BPI.
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Protein Coding Gene
MGI:88318 | Cd14
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P10810
Organism: Mus musculus/domesticus
Length: 366  
Fragment?: false
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Publication
6841966 | J:35974
First Author: Schlager G
Year: 1983
Journal: J Hered
Title: Genetic study of norepinephrine in brains of mice selected for differences in blood pressure.
Volume: 74
Issue: 2
Pages: 97-100
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Publication
2402637 | J:44234
First Author: Schumann RR
Year: 1990
Journal: Science
Title: Structure and function of lipopolysaccharide binding protein.
Volume: 249
Issue: 4975
Pages: 1429-31
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Protein Domain
IPR007959 | Dino_Luciferase_N
Type: Domain
Description: Proteins in this entry belong to a family of dinoflagellate luciferase and luciferin binding proteins. Luciferase is involved in catalysing the light emitting reaction in bioluminescence and luciferin binding protein (LBP) is known to bind to luciferin (the substrate for luciferase) to stop it reacting with the enzyme and therefore switching off the bioluminescence function. The expression of these two proteins is controlled by a circadian clock at the translational level, with synthesis and degradation occurring on a daily basis [].This entry consists of a presumed N-terminal domain that is conserved between dinoflagellateluciferase and luciferin binding proteins. This domain is not, however, the catalytic part of the protein. It has been suggested that this region may mediate an interaction between LBP and Luciferase or their association with the vacuolar membrane [].
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Protein
Q67E05
Organism: Mus musculus/domesticus
Length: 483  
Fragment?: false
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Publication
11747464 | -
First Author: Okamoto OK
Year: 2001
Journal: Biochemistry
Title: Members of a dinoflagellate luciferase gene family differ in synonymous substitution rates.
Volume: 40
Issue: 51
Pages: 15862-8
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Publication
9188532 | -
First Author: Beamer LJ
Year: 1997
Journal: Science
Title: Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution.
Volume: 276
Issue: 5320
Pages: 1861-4
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Publication
21245195 | J:182881
First Author: Patel DM
Year: 2011
Journal: J Cell Sci
Title: Annexin A1 is a new functional linker between actin filaments and phagosomes during phagocytosis.
Volume: 124
Issue: Pt 4
Pages: 578-88
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Publication
20133493 | J:159190
First Author: Tsukamoto H
Year: 2010
Journal: Int Immunol
Title: Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.
Volume: 22
Issue: 4
Pages: 271-80
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Publication
29372259 | J:256966
First Author: Liu F
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Lycium Barbarum Polysaccharides Protect Retina in rd1 Mice During Photoreceptor Degeneration.
Volume: 59
Issue: 1
Pages: 597-611
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Publication
36946778 | J:335736
First Author: McCarthy WC
Year: 2023
Journal: J Immunol
Title: Innate Immune Zonation in the Liver: NF-κB (p50) Activation and C-Reactive Protein Expression in Response to Endotoxemia Are Zone Specific.
Volume: 210
Issue: 9
Pages: 1372-1385
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Publication
15240706 | J:91928
First Author: Dunzendorfer S
Year: 2004
Journal: J Immunol
Title: TLR4 is the signaling but not the lipopolysaccharide uptake receptor.
Volume: 173
Issue: 2
Pages: 1166-70
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Publication
22491257 | J:188678
First Author: Bosmann M
Year: 2012
Journal: J Immunol
Title: Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages.
Volume: 188
Issue: 10
Pages: 5086-93
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Publication
37967203 | J:343751
First Author: Ling Z
Year: 2023
Journal: Sci Transl Med
Title: Parathyroid hormone treatment partially reverses endplate remodeling and attenuates low back pain in animal models of spine degeneration.
Volume: 15
Issue: 722
Pages: eadg8982
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Publication
30422989 | J:267722
First Author: Wang L
Year: 2018
Journal: PLoS Biol
Title: H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells.
Volume: 16
Issue: 11
Pages: e2006522
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Publication
32141651 | J:307716
First Author: Liu C
Year: 2020
Journal: Andrologia
Title: Lycium barbarum polysaccharide protects against ethanol-induced spermiotoxicity and testicular degeneration in Immp2l+/- mice.
Volume: 52
Issue: 4
Pages: e13554
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Publication
26771636 | J:289745
 
First Author: Shi Z
Year: 2016
Journal: Nutrients
Title: Protection against Oxygen-Glucose Deprivation/Reperfusion Injury in Cortical Neurons by Combining Omega-3 Polyunsaturated Acid with Lyciumbarbarum Polysaccharide.
Volume: 8
Issue: 1
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Publication
31720045 | J:286161
First Author: Hong J
Year: 2019
Journal: Immune Netw
Title: Neutrophilic Granule Protein Is a Novel Murine LPS Antagonist.
Volume: 19
Issue: 5
Pages: e34
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Publication
7608565 | J:26764
First Author: Satoh M
Year: 1995
Journal: J Immunol
Title: Inhibition of TNF-triggering activity of lipopolysaccharide by a proteinaceous factor from normal mouse liver extract.
Volume: 155
Issue: 2
Pages: 877-85
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Publication
9565687 | J:47194
First Author: Usui M
Year: 1998
Journal: Biochim Biophys Acta
Title: Molecular cloning, expression and tissue distribution of canine lipopolysaccharide (LPS)-binding protein.
Volume: 1397
Issue: 2
Pages: 202-12
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Publication
31875985 | J:304700
First Author: Qiu S
Year: 2020
Journal: J Cell Physiol
Title: Absence of VEGFR-1/Flt-1 signaling pathway in mice results in insensitivity to discogenic low back pain in an established disc injury mouse model.
Volume: 235
Issue: 6
Pages: 5305-5317
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Protein
P55065
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
Q8C186
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: false
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Protein
A2A5K2
Organism: Mus musculus/domesticus
Length: 441  
Fragment?: false
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Protein
Q3UFS5
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
Q4FJT5
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
Q3V1D7
Organism: Mus musculus/domesticus
Length: 507  
Fragment?: false
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Publication
24586312 | J:208464
First Author: Kayashima Y
Year: 2014
Journal: PLoS One
Title: Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice.
Volume: 9
Issue: 2
Pages: e88274
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Publication
15769750 | J:99925
First Author: Ferdinandusse S
Year: 2005
Journal: J Biol Chem
Title: Developmental changes of bile acid composition and conjugation in L- and D-bifunctional protein single and double knockout mice.
Volume: 280
Issue: 19
Pages: 18658-66
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Publication
23015294 | J:190951
First Author: Ge Q
Year: 2012
Journal: Endocrinology
Title: MicroRNAs regulated by adiponectin as novel targets for controlling adipose tissue inflammation.
Volume: 153
Issue: 11
Pages: 5285-96
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Publication
30977543 | J:295836
First Author: Nakawaki M
Year: 2019
Journal: J Orthop Res
Title: Changes in Nerve Growth Factor Expression and Macrophage Phenotype Following Intervertebral Disc Injury in Mice.
Volume: 37
Issue: 8
Pages: 1798-1804
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Publication
14979920 | J:355822
First Author: Stein T
Year: 2004
Journal: Breast Cancer Res
Title: Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3.
Volume: 6
Issue: 2
Pages: R75-91
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