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Search results 1 to 100 out of 751 for Bmp6

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9.569s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:5447308
Assay Type: RNA in situ
Annotation Date: 2013-01-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3262326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5447319
Age: embryonic day 18.0
Image: 2A bmp6
Note: Abundant expression in mature, early hypertrophic and hypertrophic chondrocytes.
Specimen Label: 2A bmp6
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3043220
Assay Type: RNA in situ
Annotation Date: 2004-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1914326
Stage: TS26
Assay Id: MGI:3043259
Age: embryonic day 18.5
Image: 5 -/- femur BMP6
Specimen Label: 5 -/- femur BMP6
Detected: false
Specimen Num: 3
GXD Expression
Probe: MGI:3043220
Assay Type: RNA in situ
Annotation Date: 2004-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3043259
Age: embryonic day 18.5
Image: 5 +/+ tibia BMP6
Note: Expression was detected in prehypertrophic and hypertrophic chondrocytes but was weak in terminal hypertrophic chondrocytes.
Specimen Label: 5 +/+ tibia BMP6
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3043220
Assay Type: RNA in situ
Annotation Date: 2004-06-22
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3043259
Age: embryonic day 18.5
Image: 5 -/- tibia BMP6
Note: Expression was weak in prehypertrophic and hypertrophic chondrocytes and was decreased in terminal hypertrophic chondrocytes.
Specimen Label: 5 -/- tibia BMP6
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3654028
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3654477
Age: embryonic day 17.5
Image: 2
Specimen Label: BMP6
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3654028
Assay Type: RT-PCR
Annotation Date: 2006-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737319
Stage: TS19
Assay Id: MGI:3654530
Age: embryonic day 11.5
Image: 2
Specimen Label: BMP6
Detected: true
Specimen Num: 2
Publication
First Author: Solloway MJ
Year: 1998
Journal: Dev Genet
Title: Mice lacking Bmp6 function.
Volume: 22
Issue: 4
Pages: 321-39
GXD Expression    
Probe: MGI:4938625
Assay Type: RT-PCR
Annotation Date: 2011-02-28
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:4938641
Age: embryonic day 12.5
Image: 5
Specimen Label: Bmp6 +/+
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4938625
Assay Type: RT-PCR
Annotation Date: 2011-02-28
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:4938655
Age: embryonic day 12.5
Image: 5
Specimen Label: Bmp6 +/+
Detected: true
Specimen Num: 7
Publication
First Author: Gitelman SE
Year: 1997
Journal: Mamm Genome
Title: Structure and sequence of the mouse Bmp6 gene.
Volume: 8
Issue: 3
Pages: 212-4
Publication
First Author: Zhang Z
Year: 2014
Journal: PLoS One
Title: Bmp6 expression can be regulated independently of liver iron in mice.
Volume: 9
Issue: 1
Pages: e84906
Publication
First Author: Meynard D
Year: 2009
Journal: Nat Genet
Title: Lack of the bone morphogenetic protein BMP6 induces massive iron overload.
Volume: 41
Issue: 4
Pages: 478-81
Publication  
First Author: Lu XD
Year: 2019
Journal: Biomed Pharmacother
Title: Suppression of miR-451a accelerates osteogenic differentiation and inhibits bone loss via Bmp6 signaling during osteoporosis.
Volume: 120
Pages: 109378
Publication
First Author: Hadziahmetovic M
Year: 2011
Journal: Am J Pathol
Title: Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration.
Volume: 179
Issue: 1
Pages: 335-48
Publication
First Author: Andriopoulos B Jr
Year: 2009
Journal: Nat Genet
Title: BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.
Volume: 41
Issue: 4
Pages: 482-7
Publication
First Author: Kim RY
Year: 2001
Journal: Dev Biol
Title: Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart.
Volume: 235
Issue: 2
Pages: 449-66
Publication
First Author: Kugimiya F
Year: 2005
Journal: J Biol Chem
Title: Involvement of endogenous bone morphogenetic protein (BMP) 2 and BMP6 in bone formation.
Volume: 280
Issue: 42
Pages: 35704-12
Publication
First Author: Latour C
Year: 2017
Journal: Blood
Title: Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge.
Volume: 130
Issue: 21
Pages: 2339-2343
Publication  
First Author: Radhakrishnan K
Year: 2020
Journal: Int J Mol Sci
Title: Orphan Nuclear Receptor ERRγ Is a Novel Transcriptional Regulator of IL-6 Mediated Hepatic BMP6 Gene Expression in Mice.
Volume: 21
Issue: 19
GXD Expression    
Probe: MGI:6168537
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189874
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Bmp6
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6168537
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189874
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Bmp6
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6168537
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189874
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Bmp6
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6168537
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189874
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Bmp6
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6168537
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189874
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Bmp6
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6168537
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189874
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Bmp6
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6168537
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189874
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Bmp6
Detected: true
Specimen Num: 7
Publication
First Author: Rausa M
Year: 2015
Journal: PLoS One
Title: Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?
Volume: 10
Issue: 4
Pages: e0122696
GXD Expression
Probe: MGI:9001
Assay Type: RNA in situ
Annotation Date: 1998-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:1276502
Age: embryonic day 10.5
Image: 4
Note: Expression of Bmp6 is found along both the dorsal and ventral surfaces of the developing CNS. Results are from 3-d reconstruction of multiple sections.
Specimen Label: 4
Detected: true
Specimen Num: 1
Publication
First Author: Arndt S
Year: 2019
Journal: J Invest Dermatol
Title: Bone Morphogenetic Protein-6 Inhibits Fibrogenesis in Scleroderma Offering Treatment Options for Fibrotic Skin Disease.
Volume: 139
Issue: 9
Pages: 1914-1924.e6
Publication
First Author: Stieglitz D
Year: 2019
Journal: Oncogene
Title: BMP6-induced modulation of the tumor micro-milieu.
Volume: 38
Issue: 5
Pages: 609-621
Publication
First Author: Lenoir A
Year: 2011
Journal: Blood
Title: Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.
Volume: 117
Issue: 2
Pages: 647-50
Publication
First Author: Yin H
Year: 2020
Journal: Sci Rep
Title: Inhibition of bone morphogenetic protein 6 receptors ameliorates Sjögren's syndrome in mice.
Volume: 10
Issue: 1
Pages: 2967
Publication
First Author: Shimizu M
Year: 2002
Journal: Mamm Genome
Title: A congenic mouse and candidate gene at the Chromosome 13 locus regulating bone density.
Volume: 13
Issue: 7
Pages: 335-40
Publication
First Author: Zhao L
Year: 2014
Journal: Am J Pathol
Title: A high serum iron level causes mouse retinal iron accumulation despite an intact blood-retinal barrier.
Volume: 184
Issue: 11
Pages: 2862-7
Publication
First Author: Ren R
Year: 2007
Journal: Blood
Title: Gene expression profiles identify a role for cyclooxygenase 2-dependent prostanoid generation in BMP6-induced angiogenic responses.
Volume: 109
Issue: 7
Pages: 2847-53
Publication
First Author: Simic P
Year: 2006
Journal: J Biol Chem
Title: Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption.
Volume: 281
Issue: 35
Pages: 25509-21
Publication
First Author: Zhang AS
Year: 2010
Journal: J Biol Chem
Title: The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.
Volume: 285
Issue: 22
Pages: 16416-23
Publication
First Author: Díaz-Moreno M
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology.
Volume: 115
Issue: 45
Pages: 11625-11630
Publication
First Author: Butler SJ
Year: 2003
Journal: Neuron
Title: A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons.
Volume: 38
Issue: 3
Pages: 389-401
Publication
First Author: Sugiura K
Year: 2010
Journal: Biol Reprod
Title: Does bone morphogenetic protein 6 (BMP6) affect female fertility in the mouse?
Volume: 83
Issue: 6
Pages: 997-1004
Publication
First Author: Hahn GV
Year: 1992
Journal: Genomics
Title: A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7.
Volume: 14
Issue: 3
Pages: 759-62
Publication
First Author: Wang CY
Year: 2019
Journal: Am J Hematol
Title: Iron, erythropoietin, and inflammation regulate hepcidin in Bmp2-deficient mice, but serum iron fails to induce hepcidin in Bmp6-deficient mice.
Volume: 94
Issue: 2
Pages: 240-248
Publication
First Author: Moser M
Year: 2003
Journal: Mol Cell Biol
Title: BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation.
Volume: 23
Issue: 16
Pages: 5664-79
Publication
First Author: Canali S
Year: 2017
Journal: Blood
Title: Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.
Volume: 129
Issue: 4
Pages: 405-414
Publication
First Author: Kautz L
Year: 2008
Journal: Blood
Title: Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.
Volume: 112
Issue: 4
Pages: 1503-9
Publication
First Author: Kettunen P
Year: 2006
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base.
Volume: 288
Issue: 12
Pages: 1250-8
Publication
First Author: Furuta Y
Year: 1997
Journal: Development
Title: Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development.
Volume: 124
Issue: 11
Pages: 2203-12
Publication
First Author: Inada M
Year: 1999
Journal: Dev Dyn
Title: Maturational disturbance of chondrocytes in Cbfa1-deficient mice.
Volume: 214
Issue: 4
Pages: 279-90
Publication
First Author: Wang CY
Year: 2020
Journal: Blood
Title: Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3.
Volume: 135
Issue: 6
Pages: 453-456
Publication
First Author: Iwasaki M
Year: 1997
Journal: Mech Dev
Title: Expression of indian hedgehog, bone morphogenetic protein 6 and gli during skeletal morphogenesis.
Volume: 69
Issue: 1-2
Pages: 197-202
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Gitelman SE
Year: 1994
Journal: J Cell Biol
Title: Recombinant Vgr-1/BMP-6-expressing tumors induce fibrosis and endochondral bone formation in vivo.
Volume: 126
Issue: 6
Pages: 1595-609
Publication
First Author: Lyons K
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily.
Volume: 86
Issue: 12
Pages: 4554-8
Publication
First Author: Blessing M
Year: 1996
Journal: J Cell Biol
Title: Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions.
Volume: 135
Issue: 1
Pages: 227-39
Publication
First Author: Perry MJ
Year: 2008
Journal: Bone
Title: Impaired growth plate function in bmp-6 null mice.
Volume: 42
Issue: 1
Pages: 216-25
Publication
First Author: Dendooven A
Year: 2011
Journal: Am J Pathol
Title: Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis.
Volume: 178
Issue: 3
Pages: 1069-79
Publication  
First Author: Pauk M
Year: 2021
Journal: Int J Mol Med
Title: Iron overload in aging Bmp6‑/‑ mice induces exocrine pancreatic injury and fibrosis due to acinar cell loss.
Volume: 47
Issue: 4
Publication
First Author: Drozdoff V
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Expression and growth inhibitory effect of decapentaplegic Vg-related protein 6: evidence for a regulatory role in keratinocyte differentiation.
Volume: 91
Issue: 12
Pages: 5528-32
Publication
First Author: Gitelman SE
Year: 1995
Journal: Cell Growth Differ
Title: Vgr-1/BMP-6 induces osteoblastic differentiation of pluripotential mesenchymal cells.
Volume: 6
Issue: 7
Pages: 827-36
Publication
First Author: Wall NA
Year: 1993
Journal: J Cell Biol
Title: Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6).
Volume: 120
Issue: 2
Pages: 493-502
GXD Expression      
Probe: MGI:1332074
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1332075
Age: embryonic day 7.5
Specimen Label: 1x
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1332074
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1332075
Age: embryonic day 7.5
Specimen Label: 10x
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1332074
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1332075
Age: embryonic day 7.5
Specimen Label: 100x
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1332074
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1332075
Age: embryonic day 7.5
Specimen Label: 1x
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1332074
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1332075
Age: embryonic day 7.5
Specimen Label: 10x
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1332074
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1332075
Age: embryonic day 7.5
Specimen Label: 100x
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2661351
Assay Type: Northern blot
Annotation Date: 2003-05-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661418
Age: postnatal week 2
Image: 7
Specimen Label: 2 brain
Specimen Num: 2
GXD Expression      
Probe: MGI:2661351
Assay Type: Northern blot
Annotation Date: 2003-05-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661418
Age: postnatal month 6-9
Image: 7
Specimen Label: 3 brain
Specimen Num: 3
GXD Expression      
Probe: MGI:2661351
Assay Type: Northern blot
Annotation Date: 2003-05-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2661418
Age: postnatal week 2
Image: 7
Specimen Label: 4 spleen
Specimen Num: 4
GXD Expression      
Probe: MGI:2661351
Assay Type: Northern blot
Annotation Date: 2003-05-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2661418
Age: postnatal month 6-9
Image: 7
Specimen Label: 5 spleen
Specimen Num: 5
GXD Expression    
Probe: MGI:2661351
Assay Type: Northern blot
Annotation Date: 2003-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2661418
Age: postnatal week 2
Image: 7
Specimen Label: 6 lung
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2661351
Assay Type: Northern blot
Annotation Date: 2003-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2661418
Age: postnatal month 6-9
Image: 7
Specimen Label: 7 lung
Detected: true
Specimen Num: 7