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Search results 1701 to 1800 out of 7122 for App

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Type Details Score
Publication
25599931 | J:284014
First Author: Filser S
Year: 2015
Journal: Biol Psychiatry
Title: Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions.
Volume: 77
Issue: 8
Pages: 729-39
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HT Experiment
GSE181936 | Regulation of gene expression by the APP family in the adult cerebral cortex
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
App<tm1.2Tlyp> | MGI:6111357
Name: amyloid beta precursor protein; targeted mutation 1.2, Tracy L Young-Pearse
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
19828212 | J:169998
First Author: Vogt DL
Year: 2011
Journal: Neurobiol Aging
Title: Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain.
Volume: 32
Issue: 9
Pages: 1725-9
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Publication
30456346 | J:284846
First Author: Voytyuk I
Year: 2018
Journal: Life Sci Alliance
Title: BACE2 distribution in major brain cell types and identification of novel substrates.
Volume: 1
Issue: 1
Pages: e201800026
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Publication
30232227 | J:266958
 
First Author: Ou-Yang MH
Year: 2018
Journal: Sci Transl Med
Title: Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice.
Volume: 10
Issue: 459
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Publication
11406613 | J:77414
First Author: Roberds SL
Year: 2001
Journal: Hum Mol Genet
Title: BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics.
Volume: 10
Issue: 12
Pages: 1317-24
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Publication
15080893 | J:89370
First Author: Pastorino L
Year: 2004
Journal: Mol Cell Neurosci
Title: BACE (beta-secretase) modulates the processing of APLP2 in vivo.
Volume: 25
Issue: 4
Pages: 642-9
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Publication
26923405 | J:234508
 
First Author: Jiang Y
Year: 2016
Journal: Neurobiol Aging
Title: Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF.
Volume: 39
Pages: 90-8
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HT Experiment
E-GEOD-25926 | Comparative transcriptome profiling of Amyloid Precursor Protein APP family members in the adult cortex
Series Id: GSE25926
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
16387391 | J:117963
First Author: Chiocco MJ
Year: 2007
Journal: Neurobiol Aging
Title: Spatial and temporal control of age-related APP processing in genomic-based beta-secretase transgenic mice.
Volume: 28
Issue: 1
Pages: 75-84
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Allele
Tg(Thy1-APP<SL>)28Lpr | MGI:3510606
Name: transgene insertion 28, Laurent Pradier
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
15254013 | J:101523
First Author: Krezowski J
Year: 2004
Journal: Hum Mol Genet
Title: Identification of loci determining susceptibility to the lethal effects of amyloid precursor protein transgene overexpression.
Volume: 13
Issue: 18
Pages: 1989-97
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Publication
29507146 | J:261021
First Author: Hartmann S
Year: 2018
Journal: J Neurosci
Title: β-Secretase BACE1 Promotes Surface Expression and Function of Kv3.4 at Hippocampal Mossy Fiber Synapses.
Volume: 38
Issue: 14
Pages: 3480-3494
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Publication
26280122 | J:228804
First Author: Ceglia I
Year: 2015
Journal: Nat Med
Title: APP intracellular domain-WAVE1 pathway reduces amyloid-β production.
Volume: 21
Issue: 9
Pages: 1054-9
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Publication
12742740 | J:109847
First Author: Savonenko AV
Year: 2003
Journal: Neurobiol Dis
Title: Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpressing mutant APP SWE.
Volume: 12
Issue: 3
Pages: 194-211
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Publication
20886088 | J:165103
First Author: Devi L
Year: 2010
Journal: PLoS One
Title: Phospho-eIF2α level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice.
Volume: 5
Issue: 9
Pages: e12974
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Allele
Tg(Thy1-APPSweLon)41Ema | MGI:5491622
Name: transgene insertion 41, Eliezer Masliah
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
18650431 | J:142478
First Author: Cole SL
Year: 2008
Journal: J Biol Chem
Title: The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology.
Volume: 283
Issue: 44
Pages: 29621-5
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Publication
28018172 | J:289990
 
First Author: Westmark CJ
Year: 2016
Journal: Front Mol Neurosci
Title: APP Causes Hyperexcitability in Fragile X Mice.
Volume: 9
Pages: 147
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Transgene
MGI:5559447 | Tg(Thy1-APPSweAut)A7Tiwa
Type: transgene
Organism: mouse, laboratory
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Publication
33074142 | J:299802
 
First Author: Fissel JA
Year: 2020
Journal: J Neuroimmunol
Title: Macrophage-specific deletion of BACE1 does not enhance macrophage recruitment to the injured peripheral nerve.
Volume: 349
Pages: 577423
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Publication
35394029 | J:324255
 
First Author: Koller EJ
Year: 2022
Journal: Dis Model Mech
Title: Temporal and spatially controlled APP transgene expression using Cre-dependent alleles.
Volume: 15
Issue: 5
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Publication
21542009 | J:184350
First Author: Cui S
Year: 2011
Journal: J Bone Miner Res
Title: APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner.
Volume: 26
Issue: 5
Pages: 1084-98
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Publication
31527119 | J:283677
First Author: Dierich M
Year: 2019
Journal: J Neurosci
Title: β-Secretase BACE1 Is Required for Normal Cochlear Function.
Volume: 39
Issue: 45
Pages: 9013-9027
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Publication
15312967 | J:101714
First Author: Janus C
Year: 2004
Journal: Neurobiol Aging
Title: Impaired conditioned taste aversion learning in APP transgenic mice.
Volume: 25
Issue: 9
Pages: 1213-9
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Allele
App<tm1Cwe> | MGI:2154522
Name: amyloid beta precursor protein; targeted mutation 1, Charles Weissmann
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
App<tm2.1Zhe> | MGI:4838049
 
Name: amyloid beta precursor protein; targeted mutation 2.1, Hui Zheng
Allele Type: Targeted
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Allele
App<tm2.1Ldad> | MGI:4868765
 
Name: amyloid beta precursor protein; targeted mutation 2.1, Luciano D'Adamio
Allele Type: Targeted
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Allele
App<tm1.1Ldad> | MGI:4868766
 
Name: amyloid beta precursor protein; targeted mutation 1.1, Luciano D'Adamio
Allele Type: Targeted
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Allele
App<tm1.1Ehk> | MGI:6505479
 
Name: amyloid beta precursor protein; targeted mutation 1.1, Edward H Koo
Allele Type: Targeted
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Publication
12788508 | J:83983
First Author: Lüth HJ
Year: 2003
Journal: Brain Res
Title: Degeneration of beta-amyloid-associated cholinergic structures in transgenic APP SW mice.
Volume: 977
Issue: 1
Pages: 16-22
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Publication
22014620 | J:188187
First Author: Pietropaolo S
Year: 2012
Journal: Neurobiol Aging
Title: Early development of social deficits in APP and APP-PS1 mice.
Volume: 33
Issue: 5
Pages: 1002.e17-27
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Publication
20163459 | J:169511
First Author: Sala Frigerio C
Year: 2010
Journal: FEBS J
Title: beta-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins.
Volume: 277
Issue: 6
Pages: 1503-18
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Publication
12544843 | J:89844
First Author: Shie FS
Year: 2003
Journal: Neuroreport
Title: Early intraneuronal Abeta deposition in the hippocampus of APP transgenic mice.
Volume: 14
Issue: 1
Pages: 123-9
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Publication
22692213 | J:188841
First Author: Zhou L
Year: 2012
Journal: J Biol Chem
Title: The neural cell adhesion molecules L1 and CHL1 are cleaved by BACE1 protease in vivo.
Volume: 287
Issue: 31
Pages: 25927-40
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Publication
23335052 | J:197749
First Author: Hu X
Year: 2013
Journal: FASEB J
Title: Reversing hypomyelination in BACE1-null mice with Akt-DD overexpression.
Volume: 27
Issue: 5
Pages: 1868-73
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Publication
9796810 | J:319530
First Author: Calhoun ME
Year: 1998
Journal: Nature
Title: Neuron loss in APP transgenic mice.
Volume: 395
Issue: 6704
Pages: 755-6
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Publication
24907271 | J:216006
First Author: He W
Year: 2014
Journal: J Biol Chem
Title: β-site amyloid precursor protein cleaving enzyme 1(BACE1) regulates Notch signaling by controlling the cleavage of Jagged 1 (Jag1) and Jagged 2 (Jag2) proteins.
Volume: 289
Issue: 30
Pages: 20630-7
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Publication
34500034 | J:312957
 
First Author: Dai L
Year: 2021
Journal: Brain Behav Immun
Title: Elevated β-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease.
Volume: 98
Pages: 337-348
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Publication
30647119 | J:273215
First Author: Lazic D
Year: 2019
Journal: J Exp Med
Title: 3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice.
Volume: 216
Issue: 2
Pages: 279-293
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Publication
22903875 | J:280845
First Author: Cai J
Year: 2012
Journal: EMBO Mol Med
Title: β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.
Volume: 4
Issue: 9
Pages: 980-91
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Publication
36716914 | J:347459
 
First Author: Murray HC
Year: 2023
Journal: Neuroscience
Title: Progressive Spread of Beta-amyloid Pathology in an Olfactory-driven Amyloid Precursor Protein Mouse Model.
Volume: 516
Pages: 113-124
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Publication
25224257 | J:325317
First Author: Shahani N
Year: 2015
Journal: Mol Psychiatry
Title: DISC1 regulates trafficking and processing of APP and Aβ generation.
Volume: 20
Issue: 7
Pages: 874-9
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Publication
27080468 | J:240850
 
First Author: Liu L
Year: 2016
Journal: Neurobiol Dis
Title: Increased TNFR1 expression and signaling in injured peripheral nerves of mice with reduced BACE1 activity.
Volume: 93
Pages: 21-7
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Publication
16027115 | J:102154
First Author: Rockenstein E
Year: 2005
Journal: J Biol Chem
Title: High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease.
Volume: 280
Issue: 38
Pages: 32957-67
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Publication
28733897 | J:351769
First Author: Zhang J
Year: 2018
Journal: Mol Neurobiol
Title: Alleviation of Neuropathology by Inhibition of Monoacylglycerol Lipase in APP Transgenic Mice Lacking CB2 Receptors.
Volume: 55
Issue: 6
Pages: 4802-4810
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Publication
35229730 | J:321821
 
First Author: Zheng Q
Year: 2022
Journal: J Clin Invest
Title: USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation.
Volume: 132
Issue: 5
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Publication
36142484 | J:329306
 
First Author: Oh Y
Year: 2022
Journal: Int J Mol Sci
Title: SPIN90 Deficiency Ameliorates Amyloid β Accumulation by Regulating APP Trafficking in AD Model Mice.
Volume: 23
Issue: 18
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Transgene
MGI:2448167 | Tg(THY1-APP)2Somm
Type: transgene
Organism: mouse, laboratory
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Publication
28496400 | J:312462
 
First Author: Herr UM
Year: 2017
Journal: Front Mol Neurosci
Title: LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State.
Volume: 10
Pages: 118
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Publication
28119565 | J:288902
 
First Author: Baranger K
Year: 2016
Journal: Front Mol Neurosci
Title: MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro.
Volume: 9
Pages: 163
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Publication
29955078 | J:278528
First Author: Jarvela TS
Year: 2018
Journal: Sci Rep
Title: 7B2 chaperone knockout in APP model mice results in reduced plaque burden.
Volume: 8
Issue: 1
Pages: 9813
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Publication
15642747 | J:95811
First Author: Lee EB
Year: 2005
Journal: J Cell Biol
Title: BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo.
Volume: 168
Issue: 2
Pages: 291-302
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Publication
15351437 | J:102427
First Author: Motoi Y
Year: 2004
Journal: Neurosci Lett
Title: Apolipoprotein E receptor 2 is involved in neuritic plaque formation in APP sw mice.
Volume: 368
Issue: 2
Pages: 144-7
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Publication
19931251 | J:162371
First Author: Jolivalt CG
Year: 2010
Journal: Exp Neurol
Title: Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice.
Volume: 223
Issue: 2
Pages: 422-31
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Publication
26240147 | J:225794
First Author: Wang R
Year: 2015
Journal: J Biol Chem
Title: All-trans-retinoic acid reduces BACE1 expression under inflammatory conditions via modulation of nuclear factor κB (NFκB) signaling.
Volume: 290
Issue: 37
Pages: 22532-42
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Publication
26987953 | J:235878
 
First Author: Zhang JS
Year: 2016
Journal: Neuroscience
Title: Gastrodin suppresses BACE1 expression under oxidative stress condition via inhibition of the PKR/eIF2α pathway in Alzheimer's disease.
Volume: 325
Pages: 1-9
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Publication
23754390 | J:197977
First Author: Rochin L
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells.
Volume: 110
Issue: 26
Pages: 10658-63
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Publication
15509532 | J:93635
First Author: Willem M
Year: 2004
Journal: Am J Pathol
Title: beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic mice.
Volume: 165
Issue: 5
Pages: 1621-31
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Publication
26454161 | J:251329
First Author: Agsten M
Year: 2015
Journal: J Mol Cell Cardiol
Title: BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs).
Volume: 89
Issue: Pt B
Pages: 335-48
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Publication
22399757 | J:182731
First Author: Watanabe T
Year: 2012
Journal: J Neurosci
Title: FBL2 regulates amyloid precursor protein (APP) metabolism by promoting ubiquitination-dependent APP degradation and inhibition of APP endocytosis.
Volume: 32
Issue: 10
Pages: 3352-65
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Publication
17561313 | J:145823
First Author: Amritraj A
Year: 2009
Journal: Neurobiol Aging
Title: Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains.
Volume: 30
Issue: 1
Pages: 54-70
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Publication
18554321 | J:139888
First Author: Hoe HS
Year: 2008
Journal: J Neurochem
Title: Functional interactions of APP with the apoE receptor family.
Volume: 106
Issue: 6
Pages: 2263-71
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Publication
37602729 | J:350199
First Author: Li N
Year: 2023
Journal: Aging Cell
Title: Cooperative effects of SIRT1 and SIRT2 on APP acetylation.
Volume: 22
Issue: 10
Pages: e13967
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Publication
17067805 | J:134736
First Author: Karlnoski R
Year: 2007
Journal: Neurobiol Dis
Title: Up-regulation of Bcl-2 in APP transgenic mice is associated with neuroprotection.
Volume: 25
Issue: 1
Pages: 179-88
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Publication
22052506 | J:262505
First Author: Velanac V
Year: 2012
Journal: Glia
Title: Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.
Volume: 60
Issue: 2
Pages: 203-17
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Publication
26755586 | J:229925
First Author: Lee YI
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Neuregulin1 displayed on motor axons regulates terminal Schwann cell-mediated synapse elimination at developing neuromuscular junctions.
Volume: 113
Issue: 4
Pages: E479-87
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Publication
15649699 | J:95529
First Author: Schuessel K
Year: 2005
Journal: Neurobiol Dis
Title: Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice.
Volume: 18
Issue: 1
Pages: 89-99
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Publication
25100745 | J:232465
First Author: Pascual-Lucas M
Year: 2014
Journal: EMBO Mol Med
Title: Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice.
Volume: 6
Issue: 10
Pages: 1246-62
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Publication
26079110 | J:226286
 
First Author: Li F
Year: 2015
Journal: Neuroscience
Title: Icariin decreases both APP and Aβ levels and increases neurogenesis in the brain of Tg2576 mice.
Volume: 304
Pages: 29-35
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Publication
23840754 | J:204330
First Author: Müller HP
Year: 2013
Journal: PLoS One
Title: Diffusion tensor magnetic resonance imaging of the brain in APP transgenic mice: a cohort study.
Volume: 8
Issue: 6
Pages: e67630
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Publication
29444819 | J:259749
First Author: Hu X
Year: 2018
Journal: J Exp Med
Title: BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions.
Volume: 215
Issue: 3
Pages: 927-940
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Publication
23430253 | J:336904
First Author: Stützer I
Year: 2013
Journal: J Biol Chem
Title: Systematic proteomic analysis identifies β-site amyloid precursor protein cleaving enzyme 2 and 1 (BACE2 and BACE1) substrates in pancreatic β-cells.
Volume: 288
Issue: 15
Pages: 10536-47
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Publication
23026200 | J:190305
First Author: Leroy K
Year: 2012
Journal: Am J Pathol
Title: Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice.
Volume: 181
Issue: 6
Pages: 1928-40
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Publication
23999102 | J:204530
First Author: Heilbronner G
Year: 2013
Journal: EMBO Rep
Title: Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice.
Volume: 14
Issue: 11
Pages: 1017-22
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Publication
27459671 | J:249210
First Author: Ghosal K
Year: 2016
Journal: PLoS One
Title: Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer's-Like Pathological Features in Mice.
Volume: 11
Issue: 7
Pages: e0159435
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Publication
34663454 | J:348521
First Author: Rimal S
Year: 2021
Journal: Acta Neuropathol Commun
Title: Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 169
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Publication
34824365 | J:317744
First Author: Pan JX
Year: 2021
Journal: Commun Biol
Title: Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence.
Volume: 4
Issue: 1
Pages: 1326
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Publication
31646885 | J:297597
First Author: Liu T
Year: 2019
Journal: FASEB J
Title: Dual role of cofilin in APP trafficking and amyloid-β clearance.
Volume: 33
Issue: 12
Pages: 14234-14247
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Publication
37494443 | J:338544
First Author: Im E
Year: 2023
Journal: Sci Adv
Title: Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr(682)-phosphorylated APP βCTF.
Volume: 9
Issue: 30
Pages: eadg1925
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Publication
10531052 | J:43334
First Author: Vassar R
Year: 1999
Journal: Science
Title: Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Volume: 286
Issue: 5440
Pages: 735-41
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Publication
21241773 | J:170714
First Author: Jia YL
Year: 2011
Journal: Neurosci Lett
Title: Expression and significance of DSCAM in the cerebral cortex of APP transgenic mice.
Volume: 491
Issue: 2
Pages: 153-7
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Publication
16407971 | J:105158
First Author: Crameri A
Year: 2006
Journal: EMBO J
Title: The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Abeta generation in vivo.
Volume: 25
Issue: 2
Pages: 432-43
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Publication
27013422 | J:261677
 
First Author: Löffler T
Year: 2016
Journal: Mol Cell Neurosci
Title: Brain cortical cholesterol metabolism is highly affected by human APP overexpression in mice.
Volume: 74
Pages: 34-41
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Publication
20943921 | J:238454
First Author: Wang H
Year: 2010
Journal: J Neurosci
Title: Mossy fiber long-term potentiation deficits in BACE1 knock-outs can be rescued by activation of alpha7 nicotinic acetylcholine receptors.
Volume: 30
Issue: 41
Pages: 13808-13
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Publication
21880397 | J:188191
First Author: Rönnbäck A
Year: 2012
Journal: Neurobiol Aging
Title: Amyloid neuropathology in the single Arctic APP transgenic model affects interconnected brain regions.
Volume: 33
Issue: 4
Pages: 831.e11-9
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Publication
15212842 | J:102351
First Author: Jankowsky JL
Year: 2004
Journal: Neurobiol Aging
Title: APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.
Volume: 25
Issue: 7
Pages: 885-92
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Publication
19066434 | J:154969
First Author: Ozmen L
Year: 2009
Journal: Neurodegener Dis
Title: Expression of transgenic APP mRNA is the key determinant for beta-amyloid deposition in PS2APP transgenic mice.
Volume: 6
Issue: 1-2
Pages: 29-36
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Publication
15158161 | J:90592
First Author: Dedeoglu A
Year: 2004
Journal: Brain Res
Title: Magnetic resonance spectroscopic analysis of Alzheimer's disease mouse brain that express mutant human APP shows altered neurochemical profile.
Volume: 1012
Issue: 1-2
Pages: 60-5
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Publication
30853883 | J:277418
 
First Author: Höfling C
Year: 2019
Journal: Front Neurosci
Title: Cell Type-Specific Human APP Transgene Expression by Hippocampal Interneurons in the Tg2576 Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 137
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Publication
18385378 | J:133643
First Author: Savonenko AV
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice.
Volume: 105
Issue: 14
Pages: 5585-90
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Publication
17644063 | J:123487
First Author: Miyazaki H
Year: 2007
Journal: Biochem Biophys Res Commun
Title: BACE1 modulates filopodia-like protrusions induced by sodium channel beta4 subunit.
Volume: 361
Issue: 1
Pages: 43-8
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Publication
37143090 | J:357334
First Author: Zhou J
Year: 2023
Journal: Mol Neurodegener
Title: BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides.
Volume: 18
Issue: 1
Pages: 31
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Publication
24806669 | J:211050
First Author: Kallop DY
Year: 2014
Journal: J Neurosci
Title: A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models.
Volume: 34
Issue: 19
Pages: 6425-37
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Publication
22688190 | J:278130
First Author: Santuccione AC
Year: 2013
Journal: Mol Psychiatry
Title: Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice.
Volume: 18
Issue: 3
Pages: 358-68
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Allele
App<tm2Cwe> | MGI:2154535
Name: amyloid beta precursor protein; targeted mutation 2, Charles Weissmann
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
15987683 | J:100925
First Author: Dominguez D
Year: 2005
Journal: J Biol Chem
Title: Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice.
Volume: 280
Issue: 35
Pages: 30797-806
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Publication
12544850 | J:89843
First Author: Liu L
Year: 2003
Journal: Neuroreport
Title: Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice.
Volume: 14
Issue: 1
Pages: 163-6
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Publication
20615433 | J:162999
First Author: Codita A
Year: 2010
Journal: Behav Brain Res
Title: Impaired behavior of female tg-ArcSwe APP mice in the IntelliCage: A longitudinal study.
Volume: 215
Issue: 1
Pages: 83-94
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