|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1901 to 2000 out of 7122 for App

0.038s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression    
Probe: MGI:3640767
Assay Type: Western blot
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3640776
Age: embryonic day 14.0
Image: 1
Specimen Label: 100 ug protein
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3640767
Assay Type: Western blot
Annotation Date: 2006-08-15
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3640776
Age: embryonic day 14.0
Image: 1
Specimen Label: 2 ug protein
Specimen Num: 2
GXD Expression    
Probe: MGI:3640767
Assay Type: Western blot
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3640776
Age: embryonic day 14.0
Image: 1
Specimen Label: 20 ug protein
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3640767
Assay Type: Western blot
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3640776
Age: embryonic day 14.0
Image: 1
Specimen Label: 80 ug protein
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3640779
Assay Type: Northern blot
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640781
Age: postnatal
Image: S1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3640779
Assay Type: Northern blot
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640781
Age: postnatal
Image: S1
Specimen Label: -/-
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/-
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: -/-
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/+
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/-
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: -/-
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2B
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6860351
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Note: Expression was stronger in pyramidal cells.
Specimen Label: 2B
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2362026
Assay Type: RNA in situ
Annotation Date: 2023-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7530800
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3518328
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: not shown
Detected: false
Specimen Num: 8
GXD Expression  
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Note: Expression was weaker in granular cells.
Specimen Label: 2B
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2F
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Note: Expression is in oligodendrocytes.
Specimen Label: 2D
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Note: Expression was stronger in pyramidal cells.
Specimen Label: 2B
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6860351
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3518628
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: not shown
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2B
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6860351
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
Publication  
First Author: Rustay NR
Year: 2010
Journal: Brain Res
Title: Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease.
Volume: 1311
Pages: 136-47
Publication
First Author: Zandl-Lang M
Year: 2018
Journal: Biochim Biophys Acta
Title: Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Volume: 1863
Issue: 1
Pages: 40-60
Publication
First Author: Gureviciene I
Year: 2004
Journal: Neurobiol Dis
Title: Normal induction but accelerated decay of LTP in APP + PS1 transgenic mice.
Volume: 15
Issue: 2
Pages: 188-95
Publication
First Author: Van Dorpe J
Year: 2000
Journal: Am J Pathol
Title: Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.
Volume: 157
Issue: 4
Pages: 1283-98
Publication
First Author: Rockenstein E
Year: 2001
Journal: J Neurosci Res
Title: Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).
Volume: 66
Issue: 4
Pages: 573-82
Publication  
First Author: Stanga S
Year: 2018
Journal: Front Neurol
Title: A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology.
Volume: 9
Pages: 384
Publication
First Author: Morales-Corraliza J
Year: 2012
Journal: Neurobiol Aging
Title: Calpastatin modulates APP processing in the brains of β-amyloid depositing but not wild-type mice.
Volume: 33
Issue: 6
Pages: 1125.e9-18
Publication  
First Author: Beckmann N
Year: 2016
Journal: Neurobiol Aging
Title: Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor-treated APP transgenic mice.
Volume: 45
Pages: 50-60
Publication
First Author: Schnöder L
Year: 2020
Journal: FASEB J
Title: Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models.
Volume: 34
Issue: 7
Pages: 9628-9649
Publication  
First Author: Marttinen M
Year: 2020
Journal: Cells
Title: Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ.
Volume: 9
Issue: 11
Publication  
First Author: Matthes F
Year: 2018
Journal: Cell Death Discov
Title: Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis.
Volume: 4
Pages: 4
Publication  
First Author: Tian Q
Year: 2025
Journal: J Clin Invest
Title: APP lysine 612 lactylation ameliorates amyloid pathology and memory decline in Alzheimer's disease.
Volume: 135
Issue: 1
Publication  
First Author: Sáez-Orellana F
Year: 2021
Journal: JCI Insight
Title: Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity.
Volume: 6
Issue: 16
Publication
First Author: Bianchi FT
Year: 2011
Journal: PLoS One
Title: The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.
Volume: 6
Issue: 7
Pages: e22370
Allele    
Name: beta-site APP cleaving enzyme 1; wild type
Allele  
Name: APP associated premature death 1; 129S6
Allele Type: QTL
Allele  
Name: APP associated premature death 1; FVB/NCr
Allele Type: QTL
Allele  
Name: APP associated premature death 2; 129S6
Allele Type: QTL
Allele  
Name: APP associated premature death 2; FVB/NCr
Allele Type: QTL
Publication
First Author: Sadleir KR
Year: 2014
Journal: PLoS One
Title: Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.
Volume: 9
Issue: 7
Pages: e101643
Publication  
First Author: Rojo AI
Year: 2017
Journal: Redox Biol
Title: NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology.
Volume: 13
Pages: 444-451
Publication  
First Author: Adalbert R
Year: 2018
Journal: Neurobiol Aging
Title: Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport.
Volume: 68
Pages: 68-75
Publication
First Author: Lee JY
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice.
Volume: 99
Issue: 11
Pages: 7705-10
Publication
First Author: Bard F
Year: 2012
Journal: Exp Neurol
Title: Sustained levels of antibodies against Aβ in amyloid-rich regions of the CNS following intravenous dosing in human APP transgenic mice.
Volume: 238
Issue: 1
Pages: 38-43
Publication  
First Author: Späni C
Year: 2015
Journal: Acta Neuropathol Commun
Title: Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer's disease lacking functional B and T cells.
Volume: 3
Pages: 71
Publication
First Author: Luccarini I
Year: 2012
Journal: Neurosci Lett
Title: Aβ plaque-associated glial reaction as a determinant of apoptotic neuronal death and cortical gliogenesis: a study in APP mutant mice.
Volume: 506
Issue: 1
Pages: 94-9
Publication
First Author: Hamm V
Year: 2017
Journal: Sci Adv
Title: Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimer's disease.
Volume: 3
Issue: 2
Pages: e1601068
Publication
First Author: Zhang B
Year: 2005
Journal: Am J Pathol
Title: Impaired rapid eye movement sleep in the Tg2576 APP murine model of Alzheimer's disease with injury to pedunculopontine cholinergic neurons.
Volume: 167
Issue: 5
Pages: 1361-9
Publication
First Author: Fitz NF
Year: 2015
Journal: Brain
Title: Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice.
Volume: 138
Issue: Pt 12
Pages: 3699-715
Publication
First Author: Li F
Year: 2004
Journal: J Neurochem
Title: Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice.
Volume: 89
Issue: 5
Pages: 1308-12
Publication  
First Author: Yoshikawa M
Year: 2018
Journal: Front Neurosci
Title: Tau Depletion in APP Transgenic Mice Attenuates Task-Related Hyperactivation of the Hippocampus and Differentially Influences Locomotor Activity and Spatial Memory.
Volume: 12
Pages: 124
Publication
First Author: Kim MY
Year: 2011
Journal: J Cell Sci
Title: Regulation of Notch1 signaling by the APP intracellular domain facilitates degradation of the Notch1 intracellular domain and RBP-Jk.
Volume: 124
Issue: Pt 11
Pages: 1831-43
Publication  
First Author: Zhang X
Year: 2021
Journal: J Exp Med
Title: An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo.
Volume: 218
Issue: 6
Publication
First Author: Bretou M
Year: 2024
Journal: Dev Cell
Title: Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites.
Volume: 59
Issue: 12
Pages: 1571-1592.e9
Publication
First Author: Esterházy D
Year: 2011
Journal: Cell Metab
Title: Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass.
Volume: 14
Issue: 3
Pages: 365-77
Publication  
First Author: Natunen T
Year: 2016
Journal: Neurobiol Dis
Title: Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Volume: 85
Pages: 187-205
Publication
First Author: Kim DY
Year: 2011
Journal: J Biol Chem
Title: Reduced sodium channel Na(v)1.1 levels in BACE1-null mice.
Volume: 286
Issue: 10
Pages: 8106-16