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Search results 401 to 500 out of 581 for Mpl

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Hits by Strain

Hits by Category

Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3540526
Stage: TS26
Assay Id: MGI:6400421
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3540527
Stage: TS27
Assay Id: MGI:6400421
Age: postnatal day 0
Specimen Label: P0
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3540528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3540528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 7
Note: Relatively high expression.
Specimen Label: P7
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3540528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821528
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 4
Specimen Label: P4
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1821528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1821526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6400421
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1821527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6400421
Age: postnatal day 0
Note: Relatively high expression.
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1821528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal adult
Note: Relatively high expression.
Specimen Label: Adult
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756323
Stage: TS23
Assay Id: MGI:6400353
Age: embryonic day 15.5
Image: 2C
Note: The green labelling on the blood vessels is unspecific.
Specimen Label: 2C
Detected: false
Specimen Num: 11
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6400421
Age: embryonic day 18.5
Note: r1
Specimen Label: E18.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 4
Note: r1
Specimen Label: P4
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 7
Note: r1
Specimen Label: P7
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal adult
Note: r1. Relatively high expression.
Specimen Label: Adult
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756327
Stage: TS27
Assay Id: MGI:6400353
Age: postnatal day 1
Image: 1A anti human middle -/-
Specimen Label: 1A anti human middle -/-
Detected: false
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756327
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6400353
Age: postnatal day 1
Image: 1A anti human middle +/+
Note: Expressed in ventro-caudal region.
Specimen Label: 1A anti human middle +/+
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6400353
Age: embryonic day 18.5
Image: 2G
Note: Expressed in dorsal pons.
Specimen Label: 2G
Detected: true
Specimen Num: 15
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•
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•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6400421
Age: postnatal day 0
Note: r1. Relatively high expression. Expressed as clusters of positive cells.
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3665526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6400421
Age: embryonic day 18.5
Note: Relatively high expression.
Specimen Label: E18.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3665528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400353
Age: postnatal adult
Image: 3I
Specimen Label: 3I
Detected: true
Specimen Num: 28
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3665527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6400421
Age: postnatal day 0
Note: Relatively high expression.
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3665528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3665528
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 7
Specimen Label: P7
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3665528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal adult
Note: Relatively high expression.
Specimen Label: Adult
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757720
Stage: TS20
Assay Id: MGI:6400353
Age: embryonic day 12.5
Specimen Label: not shown
Detected: false
Specimen Num: 41
•
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757723
Stage: TS23
Assay Id: MGI:6400353
Age: embryonic day 15.5
Specimen Label: not shown
Detected: false
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:6400353
Age: embryonic day 12.5
Specimen Label: not shown
Detected: false
Specimen Num: 41
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:6400353
Age: embryonic day 15.5
Specimen Label: not shown
Detected: false
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3521728
Stage: TS28
Assay Id: MGI:6400353
Age: postnatal day 7
Image: 4B right
Specimen Label: 4B right
Detected: false
Specimen Num: 37
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3704928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 7
Note: Expressed in the grey matter.
Specimen Label: P7
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3704926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6400421
Age: embryonic day 18.5
Note: Expressed in the grey matter. Relatively high expression.
Specimen Label: E18.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3704927
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6400421
Age: postnatal day 0
Note: Expressed in the grey matter. Relatively high expression.
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3704928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal day 4
Note: Expressed in the grey matter. Relatively high expression.
Specimen Label: P4
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6400235
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3704928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6400421
Age: postnatal adult
Note: Expressed in the grey matter. Relatively high expression.
Specimen Label: Adult
Detected: true
Specimen Num: 5
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Publication
10582337 | J:59863
First Author: Alexander WS
Year: 1999
Journal: Int J Biochem Cell Biol
Title: Thrombopoietin and the c-Mpl receptor: insights from gene targeting.
Volume: 31
Issue: 10
Pages: 1027-35
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Publication
17548465 | J:125094
First Author: Greig KT
Year: 2007
Journal: Mol Cell Biol
Title: Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development.
Volume: 27
Issue: 16
Pages: 5849-59
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Publication
25636339 | J:223526
First Author: Rozenova K
Year: 2015
Journal: Blood
Title: MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling.
Volume: 125
Issue: 11
Pages: 1730-8
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Publication
17347409 | J:145417
First Author: Abkowitz JL
Year: 2007
Journal: Blood
Title: Studies of c-Mpl function distinguish the replication of hematopoietic stem cells from the expansion of differentiating clones.
Volume: 109
Issue: 12
Pages: 5186-90
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Publication
8704234 | J:34532
First Author: Carver-Moore K
Year: 1996
Journal: Blood
Title: Low levels of erythroid and myeloid progenitors in thrombopoietin-and c-mpl-deficient mice.
Volume: 88
Issue: 3
Pages: 803-8
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Publication
16051888 | J:111935
First Author: Amano H
Year: 2005
Journal: Circ Res
Title: Thrombopoietin gene transfer-mediated enhancement of angiogenic responses to acute ischemia.
Volume: 97
Issue: 4
Pages: 337-45
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Publication
9345025 | J:43759
First Author: Bunting S
Year: 1997
Journal: Blood
Title: Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin.
Volume: 90
Issue: 9
Pages: 3423-9
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Publication
12393382 | J:82323
First Author: Xie X
Year: 2003
Journal: Blood
Title: Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs.
Volume: 101
Issue: 4
Pages: 1329-35
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Publication
9474742 | J:46035
First Author: Murone M
Year: 1998
Journal: Stem Cells
Title: Hematopoietic deficiencies in c-mpl and TPO knockout mice.
Volume: 16
Issue: 1
Pages: 1-6
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Publication
19880496 | J:157793
First Author: Saur SJ
Year: 2010
Journal: Blood
Title: Ubiquitination and degradation of the thrombopoietin receptor c-Mpl.
Volume: 115
Issue: 6
Pages: 1254-63
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Publication
- | J:82961
     
First Author: JAX National Heart, Lung and Blood Program for Genomic Applications (PGA)
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the JAX NHLBI ENU Mutagenesis Program
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Publication
12438747 | J:79791
First Author: Fröhlich L
Year: 2002
Journal: Cytogenet Genome Res
Title: Genomic structure and refined chromosomal localization of the mouse Ptch2 gene.
Volume: 97
Issue: 1-2
Pages: 106-10
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Publication
32954656 | J:329627
First Author: Märklin M
Year: 2020
Journal: J Cell Mol Med
Title: C-Cbl regulates c-MPL receptor trafficking and its internalization.
Volume: 24
Issue: 21
Pages: 12491-12503
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Publication
15138166 | J:92703
First Author: Antonchuk J
Year: 2004
Journal: Blood
Title: Synergistic effects on erythropoiesis, thrombopoiesis, and stem cell competitiveness in mice deficient in thrombopoietin and steel factor receptors.
Volume: 104
Issue: 5
Pages: 1306-13
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Publication
15665109 | J:98975
First Author: Metcalf D
Year: 2005
Journal: Blood
Title: Anomalous megakaryocytopoiesis in mice with mutations in the c-Myb gene.
Volume: 105
Issue: 9
Pages: 3480-7
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Publication
22836751 | J:191330
First Author: Coupland LA
Year: 2012
Journal: Cancer Res
Title: Platelets and P-selectin control tumor cell metastasis in an organ-specific manner and independently of NK cells.
Volume: 72
Issue: 18
Pages: 4662-71
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Publication
28744010 | J:257879
First Author: Zhan H
Year: 2018
Journal: Leukemia
Title: The JAK2V617F-bearing vascular niche promotes clonal expansion in myeloproliferative neoplasms.
Volume: 32
Issue: 2
Pages: 462-469
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Publication
15071178 | J:89601
First Author: Carpinelli MR
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling.
Volume: 101
Issue: 17
Pages: 6553-8
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Publication
19201855 | J:144799
First Author: Verhagen AM
Year: 2009
Journal: J Immunol
Title: A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency.
Volume: 182
Issue: 4
Pages: 2020-9
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Publication
22308484 | J:182022
First Author: Ng AP
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Characterization of thrombopoietin (TPO)-responsive progenitor cells in adult mouse bone marrow with in vivo megakaryocyte and erythroid potential.
Volume: 109
Issue: 7
Pages: 2364-9
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Publication
20298742 | J:164036
First Author: Coupland LA
Year: 2010
Journal: Exp Hematol
Title: A novel fluorescent-based assay reveals that thrombopoietin signaling and Bcl-X(L) influence, respectively, platelet and erythrocyte lifespans.
Volume: 38
Issue: 6
Pages: 453-461.e1
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Publication
23990627 | J:209544
First Author: Tan W
Year: 2013
Journal: J Leukoc Biol
Title: Requirement of TPO/c-mpl for IL-17A-induced granulopoiesis and megakaryopoiesis.
Volume: 94
Issue: 6
Pages: 1303-8
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Publication
9427697 | J:45321
First Author: Yamaguchi Y
Year: 1998
Journal: Blood
Title: Forced GATA-1 expression in the murine myeloid cell line M1: induction of c-Mpl expression and megakaryocytic/erythroid differentiation.
Volume: 91
Issue: 2
Pages: 450-7
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Publication
25468569 | J:261836
First Author: Xiao N
Year: 2015
Journal: Blood
Title: Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl.
Volume: 125
Issue: 6
Pages: 941-8
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Publication
8843393 | J:34634
First Author: Zhao GQ
Year: 1996
Journal: Mech Dev
Title: Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development.
Volume: 57
Issue: 2
Pages: 159-68
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Publication
7774011 | J:20132
First Author: Shivdasani RA
Year: 1995
Journal: Cell
Title: Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development.
Volume: 81
Issue: 5
Pages: 695-704
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Publication
18618018 | J:140879
First Author: Bersenev A
Year: 2008
Journal: J Clin Invest
Title: Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2.
Volume: 118
Issue: 8
Pages: 2832-44
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Publication
21149592 | J:169037
First Author: Hoffmann O
Year: 2011
Journal: Infect Immun
Title: Thrombopoietin contributes to neuronal damage in experimental bacterial meningitis.
Volume: 79
Issue: 2
Pages: 928-36
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Publication
20086247 | J:160795
First Author: Cordell PA
Year: 2010
Journal: Blood
Title: Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion.
Volume: 115
Issue: 13
Pages: 2674-81
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Publication
9108391 | J:40267
First Author: Roberts AW
Year: 1997
Journal: Blood
Title: Genetic influences determining progenitor cell mobilization and leukocytosis induced by granulocyte colony-stimulating factor.
Volume: 89
Issue: 8
Pages: 2736-44
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Publication
28596376 | J:264787
First Author: Beckers CML
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Cre/lox Studies Identify Resident Macrophages as the Major Source of Circulating Coagulation Factor XIII-A.
Volume: 37
Issue: 8
Pages: 1494-1502
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Publication
18684867 | J:140200
First Author: Kauppi M
Year: 2008
Journal: Blood
Title: Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice.
Volume: 112
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First Author: Hacein-Bey-Abina S
Year: 2020
Journal: Exp Hematol
Title: Erythropoietin is a major regulator of thrombopoiesis in thrombopoietin-dependent and -independent contexts.
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35192546 | J:325582
 
First Author: Valet C
Year: 2022
Journal: J Clin Invest
Title: Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression.
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First Author: Bernier G
Year: 1996
Journal: Genomics
Title: Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.
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Pages: 19-29
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Publication
23246483 | J:194947
First Author: de Laval B
Year: 2013
Journal: Cell Stem Cell
Title: Thrombopoietin-increased DNA-PK-dependent DNA repair limits hematopoietic stem and progenitor cell mutagenesis in response to DNA damage.
Volume: 12
Issue: 1
Pages: 37-48
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Publication
24184684 | J:207699
First Author: de Laval B
Year: 2014
Journal: Blood
Title: Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-κB pathways and their target, IEX-1.
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Pages: 509-19
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First Author: Bradley HL
Year: 2004
Journal: Blood
Title: Hematopoietic-repopulating defects from STAT5-deficient bone marrow are not fully accounted for by loss of thrombopoietin responsiveness.
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First Author: Majewski IJ
Year: 2008
Journal: PLoS Biol
Title: Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity.
Volume: 6
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Pages: e93
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First Author: Hyslop SR
Year: 2020
Journal: Oncogene
Title: Targeting platelets for improved outcome in KRAS-driven lung adenocarcinoma.
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First Author: Loughran SJ
Year: 2008
Journal: Nat Immunol
Title: The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells.
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First Author: Gainsford T
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Title: Cytokine production and function in c-mpl-deficient mice: no physiologic role for interleukin-3 in residual megakaryocyte and platelet production.
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First Author: Köhler A
Year: 2011
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Title: G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands.
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First Author: Kanaji T
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Title: Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia.
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First Author: Kohlscheen S
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Journal: Blood
Title: Endothelial protein C receptor supports hematopoietic stem cell engraftment and expansion in Mpl-deficient mice.
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20643340 | J:162629
First Author: Mei J
Year: 2010
Journal: Immunity
Title: CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection.
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First Author: Looney MR
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First Author: Ku H
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Title: Soluble thrombopoietin receptor (Mpl) and granulocyte colony-stimulating factor receptor directly stimulate proliferation of primitive hematopoietic progenitors of mice in synergy with steel factor or the ligand for Flt3/Flk2.
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Pages: 4124-31
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Allele
Mpl<tm1Wsa> | MGI:2660811
Name: myeloproliferative leukemia virus oncogene; targeted mutation 1, Warren S Alexander
Allele Type: Targeted
Attribute String: Null/knockout
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First Author: Wan M
Year: 1998
Journal: Genomics
Title: Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation.
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First Author: Stumpo DJ
Year: 2009
Journal: Blood
Title: Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis.
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Pages: 2401-10
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First Author: Parekh V
Year: 2004
Journal: Mol Cell Biol
Title: Defective extraembryonic angiogenesis in mice lacking LBP-1a, a member of the grainyhead family of transcription factors.
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First Author: Pang L
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Title: Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteins.
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First Author: Jin DK
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Title: Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes.
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Title: MOZ is essential for maintenance of hematopoietic stem cells.
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First Author: Ye TZ
Year: 2000
Journal: Gene
Title: Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein.
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First Author: Frankel WN
Year: 2009
Journal: Genes Brain Behav
Title: Szt2, a novel gene for seizure threshold in mice.
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Publication
8799165 | J:35594
First Author: Kieran MW
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.
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Pages: 9126-31
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Publication
8105016 | J:13597
First Author: Warden CH
Year: 1993
Journal: J Lipid Res
Title: Chromosomal localization of lipolytic enzymes in the mouse: pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase.
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First Author: Labosky PA
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Journal: Genomics
Title: The chromosomal mapping of four genes encoding winged helix proteins expressed early in mouse development.
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First Author: Hart A
Year: 2000
Journal: Immunity
Title: Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia.
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First Author: Goodwin N
Year: 1998
Journal: MGI Direct Data Submission
Title: An embryonic stem cell bank for producing deletion complexes in mice
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11567994 | J:115633
First Author: Pestina TI
Year: 2001
Journal: Blood
Title: Mpl ligand prevents lethal myelosuppression by inhibiting p53-dependent apoptosis.
Volume: 98
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First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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