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Search results 1 to 1 out of 1 for Hectd3

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
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Type Details Score
Protein Domain
IPR042469 | HECTD3
Type: Family
Description: E3 ubiquitin-protein ligase HECTD3 is an E3 ubiquitin ligase that regulates ubiquitination and degradation of Tara [], MASTL and LKB1 []. HECTD3 interacts with HSP90 and is involved in the HSP90-dependent degradation of CRAF protein []. It has been shown to interact and stabilize MALT1 (mucosa-associated lymphoid tissue 1), and may hence promote cell survival [].
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