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Search results 101 to 200 out of 951 for C9

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Type Details Score
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Rogne S
Year: 1989
Journal: Genomics
Title: The gene for human complement C9 is on chromosome 5.
Volume: 5
Issue: 1
Pages: 149-52
Protein
Organism: Mus musculus/domesticus
Length: 1095  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 548  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 561  
Fragment?: false
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
UniProt Feature
Begin: 21
Description: Complement component C9
Type: chain
End: 548
UniProt Feature
Begin: 34
Description: Complement component C9
Type: chain
End: 561
Publication
First Author: Tomlinson S
Year: 1995
Journal: J Immunol
Title: Chimeric horse/human recombinant C9 proteins identify the amino acid sequence in horse C9 responsible for restriction of hemolysis.
Volume: 155
Issue: 1
Pages: 436-44
Publication  
First Author: Dudkina NV
Year: 2016
Journal: Nat Commun
Title: Structure of the poly-C9 component of the complement membrane attack complex.
Volume: 7
Pages: 10588
Protein Domain
Type: Family
Description: This entry represents the complement component C9, which is a component of the membrane attack complex (MAC) which forms pores in the membranes of cells of invading organisms. MAC forms when C5 is cleaved into C5a and C5b, and C5b binds sequentially C6, C7, C8 andmultiple copies of the pore-forming subunit C9 []. C9 is the pore-forming subunit of the MAC [], and up to twenty subunits assemble to form a large beta barrel that forms a pore with a diameter of 100 angstroms in target membranes []. C9 is processed into a two-chain form, chains C9a and C9b, by thrombin []. The tertiary structure of C9 has been solved and shows the following domains (N- to C-terminal): TSP type-1, LDL-receptor class A, MACPF and EGF-like []. A variant of C9 is associated with macular degeneration of the eye [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Marazziti D
Year: 1988
Journal: Biochemistry
Title: Relationships between the gene and protein structure in human complement component C9.
Volume: 27
Issue: 17
Pages: 6529-34
Publication
First Author: Peitsch MC
Year: 1991
Journal: Curr Opin Cell Biol
Title: Assembly of macromolecular pores by immune defense systems.
Volume: 3
Issue: 4
Pages: 710-6
Publication
First Author: DiScipio RG
Year: 1984
Journal: Proc Natl Acad Sci U S A
Title: Nucleotide sequence of cDNA and derived amino acid sequence of human complement component C9.
Volume: 81
Issue: 23
Pages: 7298-302
Protein Domain
Type: Family
Description: Complement component C9 is a multi-domain protein that contains anN-terminal type-1 TSP domain, an LDL-receptor class A repeat, a number ofpotential transmembrane (TM) regions and a C-terminal EGF-like domain [, , ]. Hydropathy analysis of the sequence indicates the N-terminal half of C9 to be predominantly hydrophilic in character, while the C-terminal section is more hydrophobic. The amphipathic organisation of the primary structureis consistent with the known potential of polymerised C9 to penetrate lipidbilayers, causing the formation of transmembrane channels [, ]
Publication
First Author: Nguyen L
Year: 2020
Journal: Neuron
Title: Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model.
Volume: 105
Issue: 4
Pages: 645-662.e11
Publication
First Author: Spicer BA
Year: 2018
Journal: Nat Commun
Title: The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Volume: 9
Issue: 1
Pages: 3266
Protein
Organism: Mus musculus/domesticus
Length: 67  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
Strain
Attribute String: mutant stock, gene trap
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Stanley KK
Year: 1985
Journal: EMBO J
Title: The sequence and topology of human complement component C9.
Volume: 4
Issue: 2
Pages: 375-82
Gene
Type: gene
Organism: frog, African clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: complement component 9; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Murasawa H
Year: 2000
Journal: Anat Rec
Title: Comparative analysis of HOXC-9 gene expression in murine hemochorial and caprine synepitheliochorial placentae by in situ hybridization.
Volume: 259
Issue: 4
Pages: 383-94
Publication
First Author: Papenbrock T
Year: 1998
Journal: Dev Dyn
Title: Murine Hoxc-9 gene contains a structurally and functionally conserved enhancer.
Volume: 212
Issue: 4
Pages: 540-7
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 10
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 12
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 13
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 14
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 15
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 16
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 17
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: false
Specimen Num: 21
GXD Expression    
Probe: MGI:1205617
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1205619
Age: postnatal week 6-8
Image: st97_600
Specimen Label: None
Detected: true
Specimen Num: 22