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Search results 1 to 100 out of 197 for Mpl

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Category: Publication
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Type Details Score
Publication
8808921 | -
First Author: Mengin-Lecreulx D
Year: 1996
Journal: J Bacteriol
Title: Identification of the mpl gene encoding UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase in Escherichia coli and its role in recycling of cell wall peptidoglycan.
Volume: 178
Issue: 18
Pages: 5347-52
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Publication
19059699 | J:146577
First Author: Chan ER
Year: 2009
Journal: Exp Hematol
Title: An ENU-induced recessive mutation in Mpl leads to thrombocytopenia with overdominance.
Volume: 37
Issue: 2
Pages: 276-84
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Publication
32417303 | J:297135
 
First Author: Rommel MGE
Year: 2020
Journal: Exp Hematol
Title: Signaling properties of murine MPL and MPL mutants after stimulation with thrombopoietin and romiplostim.
Volume: 85
Pages: 33-46.e6
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Publication
11238104 | J:115585
First Author: Gaur M
Year: 2001
Journal: Blood
Title: Characterization of Mpl mutants using primary megakaryocyte-lineage cells from mpl(-/-) mice: a new system for Mpl structure-function studies.
Volume: 97
Issue: 6
Pages: 1653-61
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Publication
17634189 | J:124109
First Author: Petit-Cocault L
Year: 2007
Journal: Development
Title: Dual role of Mpl receptor during the establishment of definitive hematopoiesis.
Volume: 134
Issue: 16
Pages: 3031-40
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Publication
24711413 | J:208120
First Author: Ng AP
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation.
Volume: 111
Issue: 16
Pages: 5884-9
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Publication
21263445 | J:171008
First Author: Landrette SF
Year: 2011
Journal: Leukemia
Title: The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells.
Volume: 25
Issue: 4
Pages: 655-62
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Publication
7696972 | J:22351
 
First Author: Kaushansky K
Year: 1994
Journal: Stem Cells
Title: The mpl ligand: molecular and cellular biology of the critical regulator of megakaryocyte development.
Volume: 12 Suppl 1
Pages: 91-6; discussion 96-7
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Publication
18845793 | J:145447
First Author: Tiedt R
Year: 2009
Journal: Blood
Title: Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes.
Volume: 113
Issue: 8
Pages: 1768-77
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Publication
11008012 | J:64501
First Author: Scott CL
Year: 2000
Journal: Exp Hematol
Title: Granulocyte-macrophage colony-stimulating factor is not responsible for residual thrombopoiesis in mpl null mice.
Volume: 28
Issue: 9
Pages: 1001-7
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Publication
28034873 | J:238990
First Author: Favale F
Year: 2016
Journal: Blood
Title: An incomplete trafficking defect to the cell-surface leads to paradoxical thrombocytosis for human and murine MPL P106L.
Volume: 128
Issue: 26
Pages: 3146-3158
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Publication
18796624 | J:145455
First Author: Lannutti BJ
Year: 2009
Journal: Blood
Title: Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis.
Volume: 113
Issue: 8
Pages: 1778-85
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Publication
11980901 | J:77620
First Author: Drachman JG
Year: 2002
Journal: J Biol Chem
Title: Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation.
Volume: 277
Issue: 26
Pages: 23544-53
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Publication
20711984 | J:199353
First Author: Fleury M
Year: 2010
Journal: Int J Dev Biol
Title: Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis.
Volume: 54
Issue: 6-7
Pages: 1067-74
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Publication
8397366 | J:14725
First Author: Vigon I
Year: 1993
Journal: Oncogene
Title: Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor family: molecular cloning, chromosomal location and evidence for a function in cell growth.
Volume: 8
Issue: 10
Pages: 2607-15
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Publication
21791880 | J:304034
First Author: Strzalkowska A
Year: 2011
Journal: Exp Anim
Title: Quantitative trait loci analysis for peripheral blood parameters in a (BALB/cW × C57BL/6J-Mpl (hlb219)/J) F(2) mice.
Volume: 60
Issue: 4
Pages: 405-16
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Publication
29454962 | J:273723
First Author: Yorgan T
Year: 2018
Journal: Biochem Biophys Res Commun
Title: The high bone mass phenotype of Lrp5-mutant mice is not affected by megakaryocyte depletion.
Volume: 497
Issue: 2
Pages: 659-666
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26644453 | J:231636
First Author: Chen S
Year: 2016
Journal: Blood
Title: Sympathetic stimulation facilitates thrombopoiesis by promoting megakaryocyte adhesion, migration, and proplatelet formation.
Volume: 127
Issue: 8
Pages: 1024-35
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Publication
26912146 | J:251761
 
First Author: Liu HD
Year: 2016
Journal: J Hematol Oncol
Title: H2S protects against fatal myelosuppression by promoting the generation of megakaryocytes/platelets.
Volume: 9
Pages: 13
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Publication
8578519 | J:32676
First Author: Vainchenker W
Year: 1995
Journal: Thromb Haemost
Title: c-mpl, the thrombopoietin receptor.
Volume: 74
Issue: 1
Pages: 526-8
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Publication
29802222 | J:264753
First Author: Chen S
Year: 2018
Journal: Blood
Title: IGF-1 facilitates thrombopoiesis primarily through Akt activation.
Volume: 132
Issue: 2
Pages: 210-222
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Publication
11997107 | J:76502
First Author: Sabath DF
Year: 2002
Journal: Biochim Biophys Acta
Title: Identification and characterization of an isoform of murine Mpl.
Volume: 1574
Issue: 3
Pages: 383-6
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Publication
30005133 | J:268532
First Author: Zhang Y
Year: 2018
Journal: Stem Cells
Title: JAK2V617F Megakaryocytes Promote Hematopoietic Stem/Progenitor Cell Expansion in Mice Through Thrombopoietin/MPL Signaling.
Volume: 36
Issue: 11
Pages: 1676-1684
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Publication
21289307 | J:172851
First Author: Heckl D
Year: 2011
Journal: Blood
Title: Lentiviral gene transfer regenerates hematopoietic stem cells in a mouse model for Mpl-deficient aplastic anemia.
Volume: 117
Issue: 14
Pages: 3737-47
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Publication
10627458 | J:110258
First Author: Gainsford T
Year: 2000
Journal: Blood
Title: The residual megakaryocyte and platelet production in c-mpl-deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor.
Volume: 95
Issue: 2
Pages: 528-34
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Publication
29097774 | J:256934
First Author: Au AE
Year: 2017
Journal: Sci Rep
Title: Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling.
Volume: 7
Issue: 1
Pages: 14953
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Publication
11071383 | J:65793
First Author: Tonelli R
Year: 2000
Journal: Hum Genet
Title: Compound heterozygosity for two different amino-acid substitution mutations in the thrombopoietin receptor (c-mpl gene) in congenital amegakaryocytic thrombocytopenia (CAMT).
Volume: 107
Issue: 3
Pages: 225-33
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Publication
7862460 | J:23631
First Author: Alexander WS
Year: 1995
Journal: Oncogene
Title: Structure and transcription of the genomic locus encoding murine c-Mpl, a receptor for thrombopoietin.
Volume: 10
Issue: 4
Pages: 795-803
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Publication
10480432 | J:57076
First Author: Yan XQ
Year: 1999
Journal: Exp Hematol
Title: Ectopic overexpression of c-mpl by retroviral-mediated gene transfer suppressed megakaryopoiesis but enhanced erythropoiesis in mice.
Volume: 27
Issue: 9
Pages: 1409-17
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Publication
27748371 | J:241035
First Author: Du C
Year: 2017
Journal: Leukemia
Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1.
Volume: 31
Issue: 4
Pages: 945-956
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Publication
21115812 | J:167138
First Author: de Graaf CA
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Regulation of hematopoietic stem cells by their mature progeny.
Volume: 107
Issue: 50
Pages: 21689-94
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17637498 | J:126562
First Author: Tong W
Year: 2007
Journal: Exp Hematol
Title: Signals emanating from the membrane proximal region of the thrombopoietin receptor (mpl) support hematopoietic stem cell self-renewal.
Volume: 35
Issue: 9
Pages: 1447-55
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Publication
26147434 | J:238394
First Author: Kohlscheen S
Year: 2015
Journal: PLoS One
Title: Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance.
Volume: 10
Issue: 7
Pages: e0131866
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Publication
32958856 | J:327126
First Author: Xu L
Year: 2020
Journal: Nat Cell Biol
Title: Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions.
Volume: 22
Issue: 10
Pages: 1162-1169
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Publication
28622305 | J:276266
First Author: Zingariello M
Year: 2017
Journal: Blood Cancer J
Title: The thrombopoietin/MPL axis is activated in the Gata1low mouse model of myelofibrosis and is associated with a defective RPS14 signature.
Volume: 7
Issue: 6
Pages: e572
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Publication
9892696 | J:123715
First Author: Stoffel R
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Permissive role of thrombopoietin and granulocyte colony-stimulating factor receptors in hematopoietic cell fate decisions in vivo.
Volume: 96
Issue: 2
Pages: 698-702
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8334987 | J:12827
First Author: Skoda RC
Year: 1993
Journal: EMBO J
Title: Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.
Volume: 12
Issue: 7
Pages: 2645-53
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Publication
32479500 | J:289626
First Author: Spivak JL
Year: 2020
Journal: PLoS One
Title: Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia vera.
Volume: 15
Issue: 6
Pages: e0232801
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Publication
25339357 | J:220785
First Author: Sangkhae V
Year: 2014
Journal: Blood
Title: The thrombopoietin receptor, MPL, is critical for development of a JAK2V617F-induced myeloproliferative neoplasm.
Volume: 124
Issue: 26
Pages: 3956-63
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Publication
15337790 | J:93918
First Author: Tong W
Year: 2004
Journal: J Exp Med
Title: Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.
Volume: 200
Issue: 5
Pages: 569-80
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Publication
24043765 | J:219400
First Author: Takyar S
Year: 2013
Journal: J Exp Med
Title: VEGF controls lung Th2 inflammation via the miR-1-Mpl (myeloproliferative leukemia virus oncogene)-P-selectin axis.
Volume: 210
Issue: 10
Pages: 1993-2010
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Publication
14662325 | J:86968
First Author: Pestina TI
Year: 2003
Journal: Exp Hematol
Title: Differential role of Stat5 isoforms in effecting hematopoietic recovery induced by Mpl-ligand in lethally myelosuppressed mice.
Volume: 31
Issue: 12
Pages: 1198-205
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Publication
7534285 | J:23762
First Author: Drachman JG
Year: 1995
Journal: J Biol Chem
Title: The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl.
Volume: 270
Issue: 10
Pages: 4979-82
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Publication
25995324 | J:225923
First Author: Potts KS
Year: 2015
Journal: Blood
Title: Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL.
Volume: 126
Issue: 6
Pages: 807-16
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Publication
20667107 | J:163547
 
First Author: Ivanova A
Year: 2010
Journal: BMC Dev Biol
Title: Expression pattern of the thrombopoietin receptor (Mpl) in the murine central nervous system.
Volume: 10
Pages: 77
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8073287 | J:83264
First Author: Gurney AL
Year: 1994
Journal: Science
Title: Thrombocytopenia in c-mpl-deficient mice.
Volume: 265
Issue: 5177
Pages: 1445-7
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Publication
30209246 | J:266994
 
First Author: Kao YR
Year: 2018
Journal: Sci Transl Med
Title: Thrombopoietin receptor-independent stimulation of hematopoietic stem cells by eltrombopag.
Volume: 10
Issue: 458
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28329764 | J:252516
First Author: Lefrançais E
Year: 2017
Journal: Nature
Title: The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors.
Volume: 544
Issue: 7648
Pages: 105-109
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10611229 | J:87416
First Author: Luoh SM
Year: 2000
Journal: Mol Cell Biol
Title: Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo.
Volume: 20
Issue: 2
Pages: 507-15
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8630374 | J:110858
First Author: Fielder PJ
Year: 1996
Journal: Blood
Title: Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets.
Volume: 87
Issue: 6
Pages: 2154-61
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8630375 | J:32131
First Author: Alexander WS
Year: 1996
Journal: Blood
Title: Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl.
Volume: 87
Issue: 6
Pages: 2162-70
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37992231 | J:346615
First Author: Ningtyas DC
Year: 2024
Journal: Blood
Title: Platelets mediate the clearance of senescent red blood cells by forming prophagocytic platelet-cell complexes.
Volume: 143
Issue: 6
Pages: 535-547
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20538807 | J:164512
First Author: Winter O
Year: 2010
Journal: Blood
Title: Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow.
Volume: 116
Issue: 11
Pages: 1867-75
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25865259 | J:224700
First Author: Storan MJ
Year: 2015
Journal: Stem Cells
Title: Brief Report: Factors Released by Megakaryocytes Thrombin Cleave Osteopontin to Negatively Regulate Hematopoietic Stem Cells.
Volume: 33
Issue: 7
Pages: 2351-7
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Publication
19197068 | J:144465
First Author: McMorran BJ
Year: 2009
Journal: Science
Title: Platelets kill intraerythrocytic malarial parasites and mediate survival to infection.
Volume: 323
Issue: 5915
Pages: 797-800
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9448308 | J:45659
First Author: Kimura S
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin.
Volume: 95
Issue: 3
Pages: 1195-200
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11493447 | J:115603
First Author: Levin J
Year: 2001
Journal: Blood
Title: Thrombocytopenic c-mpl(-/-) mice can produce a normal level of platelets after administration of 5-fluorouracil: the effect of age on the response.
Volume: 98
Issue: 4
Pages: 1019-27
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22628264 | J:194567
First Author: Du J
Year: 2012
Journal: Stem Cells
Title: Signaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells.
Volume: 30
Issue: 7
Pages: 1447-54
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36223471 | J:330589
First Author: Roweth HG
Year: 2022
Journal: Sci Adv
Title: Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer.
Volume: 8
Issue: 41
Pages: eabo5224
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2539212 | J:9693
First Author: Wendling F
Year: 1989
Journal: Blood
Title: Factor-independent erythropoietic progenitor cells in leukemia induced by the myeloproliferative leukemia virus.
Volume: 73
Issue: 5
Pages: 1161-7
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7536928 | J:24396
First Author: Kaushansky K
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.
Volume: 92
Issue: 8
Pages: 3234-8
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7759951 | J:25765
First Author: Broudy VC
Year: 1995
Journal: J Leukoc Biol
Title: Thrombopoietin, the c-mpl ligand, is a major regulator of platelet production.
Volume: 57
Issue: 5
Pages: 719-25
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10077649 | J:54299
First Author: Ihara K
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia.
Volume: 96
Issue: 6
Pages: 3132-6
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12130527 | J:132384
First Author: Ziegler S
Year: 2002
Journal: Blood
Title: A 2-kb c-mpl promoter fragment is sufficient to direct expression to the megakaryocytic lineage and sites of embryonic hematopoiesis in transgenic mice.
Volume: 100
Issue: 3
Pages: 1072-4
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19302922 | J:147035
First Author: Fox NE
Year: 2009
Journal: Exp Hematol
Title: Compound heterozygous c-Mpl mutations in a child with congenital amegakaryocytic thrombocytopenia: functional characterization and a review of the literature.
Volume: 37
Issue: 4
Pages: 495-503
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21892137 | J:180038
First Author: Staerk J
Year: 2011
Journal: EMBO J
Title: Orientation-specific signalling by thrombopoietin receptor dimers.
Volume: 30
Issue: 21
Pages: 4398-413
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23359689 | J:194326
First Author: Defour JP
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Tryptophan at the transmembrane-cytosolic junction modulates thrombopoietin receptor dimerization and activation.
Volume: 110
Issue: 7
Pages: 2540-5
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10582337 | J:59863
First Author: Alexander WS
Year: 1999
Journal: Int J Biochem Cell Biol
Title: Thrombopoietin and the c-Mpl receptor: insights from gene targeting.
Volume: 31
Issue: 10
Pages: 1027-35
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17548465 | J:125094
First Author: Greig KT
Year: 2007
Journal: Mol Cell Biol
Title: Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development.
Volume: 27
Issue: 16
Pages: 5849-59
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25636339 | J:223526
First Author: Rozenova K
Year: 2015
Journal: Blood
Title: MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling.
Volume: 125
Issue: 11
Pages: 1730-8
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16051888 | J:111935
First Author: Amano H
Year: 2005
Journal: Circ Res
Title: Thrombopoietin gene transfer-mediated enhancement of angiogenic responses to acute ischemia.
Volume: 97
Issue: 4
Pages: 337-45
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8704234 | J:34532
First Author: Carver-Moore K
Year: 1996
Journal: Blood
Title: Low levels of erythroid and myeloid progenitors in thrombopoietin-and c-mpl-deficient mice.
Volume: 88
Issue: 3
Pages: 803-8
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9345025 | J:43759
First Author: Bunting S
Year: 1997
Journal: Blood
Title: Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin.
Volume: 90
Issue: 9
Pages: 3423-9
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17347409 | J:145417
First Author: Abkowitz JL
Year: 2007
Journal: Blood
Title: Studies of c-Mpl function distinguish the replication of hematopoietic stem cells from the expansion of differentiating clones.
Volume: 109
Issue: 12
Pages: 5186-90
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12393382 | J:82323
First Author: Xie X
Year: 2003
Journal: Blood
Title: Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs.
Volume: 101
Issue: 4
Pages: 1329-35
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9474742 | J:46035
First Author: Murone M
Year: 1998
Journal: Stem Cells
Title: Hematopoietic deficiencies in c-mpl and TPO knockout mice.
Volume: 16
Issue: 1
Pages: 1-6
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19880496 | J:157793
First Author: Saur SJ
Year: 2010
Journal: Blood
Title: Ubiquitination and degradation of the thrombopoietin receptor c-Mpl.
Volume: 115
Issue: 6
Pages: 1254-63
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Publication
- | J:82961
     
First Author: JAX National Heart, Lung and Blood Program for Genomic Applications (PGA)
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the JAX NHLBI ENU Mutagenesis Program
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12438747 | J:79791
First Author: Fröhlich L
Year: 2002
Journal: Cytogenet Genome Res
Title: Genomic structure and refined chromosomal localization of the mouse Ptch2 gene.
Volume: 97
Issue: 1-2
Pages: 106-10
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Publication
32954656 | J:329627
First Author: Märklin M
Year: 2020
Journal: J Cell Mol Med
Title: C-Cbl regulates c-MPL receptor trafficking and its internalization.
Volume: 24
Issue: 21
Pages: 12491-12503
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15138166 | J:92703
First Author: Antonchuk J
Year: 2004
Journal: Blood
Title: Synergistic effects on erythropoiesis, thrombopoiesis, and stem cell competitiveness in mice deficient in thrombopoietin and steel factor receptors.
Volume: 104
Issue: 5
Pages: 1306-13
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Publication
23990627 | J:209544
First Author: Tan W
Year: 2013
Journal: J Leukoc Biol
Title: Requirement of TPO/c-mpl for IL-17A-induced granulopoiesis and megakaryopoiesis.
Volume: 94
Issue: 6
Pages: 1303-8
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Publication
15665109 | J:98975
First Author: Metcalf D
Year: 2005
Journal: Blood
Title: Anomalous megakaryocytopoiesis in mice with mutations in the c-Myb gene.
Volume: 105
Issue: 9
Pages: 3480-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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