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Search results 101 to 141 out of 141 for Ro60

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0.019s
Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
Publication
First Author: Yoo CJ
Year: 1994
Journal: Mol Cell Biol
Title: La proteins from Drosophila melanogaster and Saccharomyces cerevisiae: a yeast homolog of the La autoantigen is dispensable for growth.
Volume: 14
Issue: 8
Pages: 5412-24
Protein Domain
Type: Domain
Description: Human Ro ribonucleoproteins (RNPs) are composed of one of the four small Y RNAs and at least two proteins, Ro60 and La. The La protein is a 47kDa polypeptide that frequently acts as an autoantigen in systemic lupus erythematosus and Sjogren's syndrome []. In the nucleus, La acts as a RNA polymerase III (RNAP III) transcription factor, while in the cytoplasm, La acts as a translation factor []. In the nucleus, La binds to the 3'UTR of nascent RNAP III transcripts to assist in folding and maturation []. In the cytoplasm, La recognises specific classes of mRNAs that contain a 5'-terminal oligopyrimidine (5'TOP) motif known to control protein synthesis []. The specific recognition is mediated by the N-terminal domain of La, which comprises a La motif and a RNA recognition motif (RRM). The La motif adopts an alpha/beta fold that comprises a winged-helix motif [].Homologous La domain-containing proteins have been identified in a wide range of organisms except Archaea, bacteria and viruses [].This domain is found at the N terminus of La RNA-binding proteins as well as other proteins [].
Protein
Organism: Mus musculus/domesticus
Length: 1072  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 335  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1072  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 335  
Fragment?: false
Publication
First Author: Izumi RE
Year: 2004
Journal: J Virol
Title: A peptide from autoantigen La blocks poliovirus and hepatitis C virus cap-independent translation and reveals a single tyrosine critical for La RNA binding and translation stimulation.
Volume: 78
Issue: 7
Pages: 3763-76
Publication
First Author: Intine RV
Year: 2003
Journal: Mol Cell
Title: Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs.
Volume: 12
Issue: 5
Pages: 1301-7
Publication
First Author: Keene JD
Year: 2003
Journal: Mol Cell
Title: Posttranscriptional generation of macromolecular complexes.
Volume: 12
Issue: 6
Pages: 1347-9
Publication
First Author: Alfano C
Year: 2004
Journal: Nat Struct Mol Biol
Title: Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein.
Volume: 11
Issue: 4
Pages: 323-9
Protein
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 718  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 610  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2629  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2629  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89