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Search results 1 to 99 out of 99 for Optn

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Category: Publication
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Type Details Score
Publication
37439113 | J:338172
   
First Author: Meyer LM
Year: 2023
Journal: Autophagy
Title: Deciphering the mitophagy receptor network identifies a crucial role for OPTN (optineurin) in acute myeloid leukemia.
Pages: 1-15
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Publication
35436991 | J:324291
First Author: Hou M
Year: 2022
Journal: Cell Death Dis
Title: Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation.
Volume: 13
Issue: 4
Pages: 362
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Publication
33143524 | J:303292
   
First Author: Liu ZZ
Year: 2020
Journal: Autophagy
Title: Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3.
Pages: 1-17
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Publication
33296728 | J:300212
 
First Author: Kurashige T
Year: 2021
Journal: Neurobiol Dis
Title: Optineurin defects cause TDP43-pathology with autophagic vacuolar formation.
Volume: 148
Pages: 105215
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Publication
32171527 | J:299932
First Author: Mizuno N
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Optineurin regulates osteoblastogenesis through STAT1.
Volume: 525
Issue: 4
Pages: 889-894
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Publication
37352136 | J:337245
First Author: Fukushi M
Year: 2023
Journal: PLoS One
Title: Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased survival of mice following viral infection.
Volume: 18
Issue: 6
Pages: e0287545
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Publication
25818176 | J:222642
First Author: Tseng HC
Year: 2015
Journal: Neurobiol Aging
Title: Visual impairment in an optineurin mouse model of primary open-angle glaucoma.
Volume: 36
Issue: 6
Pages: 2201-12
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Publication
36706179 | J:357619
First Author: Hu X
Year: 2023
Journal: Sci Adv
Title: Optineurin regulates NRF2-mediated antioxidant response in a mouse model of Paget's disease of bone.
Volume: 9
Issue: 4
Pages: eade6998
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Publication
26527009 | J:228964
First Author: Obaid R
Year: 2015
Journal: Cell Rep
Title: Optineurin Negatively Regulates Osteoclast Differentiation by Modulating NF-κB and Interferon Signaling: Implications for Paget's Disease.
Volume: 13
Issue: 6
Pages: 1096-1102
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Publication
33272572 | J:305698
 
First Author: Ramachandran G
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Optineurin modulates ER stress-induced signaling pathways and cell death.
Volume: 534
Pages: 297-302
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Publication
20388642 | J:160709
First Author: Chi ZL
Year: 2010
Journal: Hum Mol Genet
Title: Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice.
Volume: 19
Issue: 13
Pages: 2606-15
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Publication
33723228 | J:303304
First Author: Zhang S
Year: 2021
Journal: Cell Death Discov
Title: The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro.
Volume: 7
Issue: 1
Pages: 49
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Publication
23669351 | J:199188
First Author: Minegishi Y
Year: 2013
Journal: Hum Mol Genet
Title: Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma.
Volume: 22
Issue: 17
Pages: 3559-67
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Publication
31076632 | J:302744
First Author: Wong SW
Year: 2020
Journal: Cell Death Differ
Title: Global deletion of Optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget's disease.
Volume: 27
Issue: 1
Pages: 71-84
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Publication
26044960 | J:223368
First Author: Chew TS
Year: 2015
Journal: Dis Model Mech
Title: Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis.
Volume: 8
Issue: 8
Pages: 817-29
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Publication
15607428 | J:95937
First Author: Rezaie T
Year: 2005
Journal: Genomics
Title: Molecular cloning, genomic structure, and protein characterization of mouse optineurin.
Volume: 85
Issue: 1
Pages: 131-8
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Publication
34707127 | J:313672
First Author: Wang J
Year: 2021
Journal: Nat Commun
Title: Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling.
Volume: 12
Issue: 1
Pages: 6198
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Publication
25026213 | J:214231
First Author: Liu Z
Year: 2014
Journal: Cancer Cell
Title: Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression.
Volume: 26
Issue: 1
Pages: 106-20
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Publication
16442524 | J:111860
First Author: Kroeber M
Year: 2006
Journal: Exp Eye Res
Title: Transgenic studies on the role of optineurin in the mouse eye.
Volume: 82
Issue: 6
Pages: 1075-85
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Publication
21896272 | J:189367
First Author: Sippl C
Year: 2011
Journal: Exp Eye Res
Title: Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins.
Volume: 93
Issue: 5
Pages: 669-80
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Publication
26677802 | J:247255
First Author: Slowicka K
Year: 2016
Journal: Eur J Immunol
Title: Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling.
Volume: 46
Issue: 4
Pages: 971-80
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Publication
28882891 | J:246096
First Author: Tanishima M
Year: 2017
Journal: J Biol Chem
Title: Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling.
Volume: 292
Issue: 42
Pages: 17250-17257
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Publication
27493188 | J:234166
First Author: Ito Y
Year: 2016
Journal: Science
Title: RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.
Volume: 353
Issue: 6299
Pages: 603-8
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Publication
29133525 | J:255919
First Author: Bansal M
Year: 2018
Journal: J Biol Chem
Title: Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein.
Volume: 293
Issue: 1
Pages: 132-147
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Publication
35476671 | J:328227
First Author: Shi XC
Year: 2022
Journal: PLoS Biol
Title: Optineurin promotes myogenesis during muscle regeneration in mice by autophagic degradation of GSK3β.
Volume: 20
Issue: 4
Pages: e3001619
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Publication
28159912 | J:246386
First Author: Bakshi S
Year: 2017
Journal: Biochem J
Title: Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β.
Volume: 474
Issue: 7
Pages: 1163-1174
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Publication
21862579 | J:243728
First Author: Gleason CE
Year: 2011
Journal: J Biol Chem
Title: Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon β.
Volume: 286
Issue: 41
Pages: 35663-74
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Publication
33628368 | J:313864
 
First Author: Cheng Y
Year: 2021
Journal: Oxid Med Cell Longev
Title: iTRAQ-Based Quantitative Proteomics Indicated Nrf2/OPTN-Mediated Mitophagy Inhibits NLRP3 Inflammasome Activation after Intracerebral Hemorrhage.
Volume: 2021
Pages: 6630281
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Publication
30017954 | J:267043
 
First Author: Markovinovic A
Year: 2018
Journal: Neuroscience
Title: Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-β Responses.
Volume: 388
Pages: 139-151
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Publication
27086836 | J:233694
First Author: Meena NP
Year: 2016
Journal: FEBS Lett
Title: The TBK1-binding domain of optineurin promotes type I interferon responses.
Volume: 590
Issue: 10
Pages: 1498-508
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Publication
35750266 | J:326746
First Author: Moharir SC
Year: 2022
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Optineurin deficiency induces patchy hair loss but it is not sufficient to cause amyotrophic lateral sclerosis in mice.
Volume: 1868
Issue: 10
Pages: 166470
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Publication
10756201 | J:61878
First Author: Moreland RJ
Year: 2000
Journal: Nucleic Acids Res
Title: Identification of a transcription factor IIIA-interacting protein.
Volume: 28
Issue: 9
Pages: 1986-93
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Publication
16569640 | J:113736
First Author: De Marco N
Year: 2006
Journal: J Biol Chem
Title: Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus.
Volume: 281
Issue: 23
Pages: 16147-56
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Publication
21059646 | J:168623
First Author: Shen X
Year: 2011
Journal: J Biol Chem
Title: Processing of optineurin in neuronal cells.
Volume: 286
Issue: 5
Pages: 3618-29
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Publication
33627378 | J:307160
     
First Author: Du W
Year: 2021
Journal: Cancer Discov
Title: Loss of optineurin drives cancer immune evasion via palmitoylation-dependent IFNGR1 lysosomal sorting and degradation.
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Publication
33766915 | J:333360
 
First Author: Mifflin L
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis.
Volume: 118
Issue: 13
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Publication
35145029 | J:321693
 
First Author: Liu D
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation.
Volume: 119
Issue: 7
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Publication
30815534 | J:273195
 
First Author: Dermentzaki G
Year: 2019
Journal: eNeuro
Title: Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo.
Volume: 6
Issue: 1
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Publication
25859013 | J:223345
First Author: Sundaramoorthy V
Year: 2015
Journal: Hum Mol Genet
Title: Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.
Volume: 24
Issue: 13
Pages: 3830-46
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Publication
17702576 | J:128397
First Author: Zhu G
Year: 2007
Journal: Curr Biol
Title: Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP.
Volume: 17
Issue: 16
Pages: 1438-43
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Publication
18552856 | J:138625
First Author: Li X
Year: 2008
Journal: Nat Med
Title: A tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney disease.
Volume: 14
Issue: 8
Pages: 863-8
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Publication
37352355 | J:338425
First Author: Hu Z
Year: 2023
Journal: Sci Adv
Title: VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.
Volume: 9
Issue: 25
Pages: eadg2339
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Publication
24244017 | J:207113
First Author: Munitic I
Year: 2013
Journal: J Immunol
Title: Optineurin insufficiency impairs IRF3 but not NF-κB activation in immune cells.
Volume: 191
Issue: 12
Pages: 6231-40
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Publication
26833786 | J:236573
First Author: Nakajo A
Year: 2016
Journal: J Cell Biol
Title: EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.
Volume: 212
Issue: 3
Pages: 297-306
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Publication
22465952 | J:183940
First Author: Toyofuku T
Year: 2012
Journal: Genes Dev
Title: Endosomal sorting by Semaphorin 4A in retinal pigment epithelium supports photoreceptor survival.
Volume: 26
Issue: 8
Pages: 816-29
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31927188 | J:287257
 
First Author: Ingham NJ
Year: 2020
Journal: Hear Res
Title: Functional analysis of candidate genes from genome-wide association studies of hearing.
Volume: 387
Pages: 107879
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Publication
15867431 | J:98896
First Author: Miyamoto-Sato E
Year: 2005
Journal: Genome Res
Title: Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexes.
Volume: 15
Issue: 5
Pages: 710-7
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28465321 | J:356661
First Author: Esteban-Martínez L
Year: 2017
Journal: EMBO J
Title: Programmed mitophagy is essential for the glycolytic switch during cell differentiation.
Volume: 36
Issue: 12
Pages: 1688-1706
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21931791 | J:177885
First Author: Brunskill EW
Year: 2011
Journal: PLoS One
Title: Defining the molecular character of the developing and adult kidney podocyte.
Volume: 6
Issue: 9
Pages: e24640
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17953485 | J:127119
First Author: Visel A
Year: 2007
Journal: PLoS Genet
Title: Regulatory pathway analysis by high-throughput in situ hybridization.
Volume: 3
Issue: 10
Pages: 1867-83
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- | J:165965
     
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
37983563 | J:357780
First Author: Wen D
Year: 2024
Journal: FEBS J
Title: OPTN gene therapy increases autophagy and protects mitochondria in SOD1-G93A-expressing transgenic mice and cells.
Volume: 291
Issue: 4
Pages: 795-813
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Publication
34861878 | J:324799
First Author: Cao LL
Year: 2021
Journal: J Neuroinflammation
Title: Downregulating expression of OPTN elevates neuroinflammation via AIM2 inflammasome- and RIPK1-activating mechanisms in APP/PS1 transgenic mice.
Volume: 18
Issue: 1
Pages: 281
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Publication
30404831 | J:269341
 
First Author: Bussi C
Year: 2018
Journal: J Cell Sci
Title: Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells.
Volume: 131
Issue: 23
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Publication
36705529 | -
First Author: Sayyad Z
Year: 2023
Journal: FEBS J
Title: A glaucoma-associated OPTN polymorphism, M98K sensitizes retinal cells to endoplasmic reticulum stress and tumour necrosis factor α.
Volume: 290
Issue: 12
Pages: 3110-3127
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Publication
23357852 | J:211234
First Author: Sirohi K
Year: 2013
Journal: Autophagy
Title: M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells.
Volume: 9
Issue: 4
Pages: 510-27
•
•
•
•
•
Publication
29400714 | J:351845
First Author: Shi Y
Year: 2018
Journal: Nat Med
Title: Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
Volume: 24
Issue: 3
Pages: 313-325
•
•
•
•
•
Publication
35018683 | J:338505
First Author: Cai GP
Year: 2022
Journal: Cell Prolif
Title: Alkbh1-mediated DNA N6-methyladenine modification regulates bone marrow mesenchymal stem cell fate during skeletal aging.
Volume: 55
Issue: 2
Pages: e13178
•
•
•
•
•
Publication
25398946 | J:219220
First Author: Osaka M
Year: 2015
Journal: Hum Mol Genet
Title: Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis.
Volume: 24
Issue: 6
Pages: 1617-29
•
•
•
•
•
Publication
30290707 | J:310931
First Author: Xu Y
Year: 2019
Journal: Autophagy
Title: The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau).
Volume: 15
Issue: 4
Pages: 583-598
•
•
•
•
•
Publication
33685483 | J:320471
First Author: Roca-Agujetas V
Year: 2021
Journal: Mol Neurodegener
Title: Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 15
•
•
•
•
•
Publication
33590792 | J:315199
First Author: Robichaud S
Year: 2021
Journal: Autophagy
Title: Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Volume: 17
Issue: 11
Pages: 3671-3689
•
•
•
•
•




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