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Search results 101 to 187 out of 187 for Ubr2

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885785
Specimen Label: UC Davis_1885785
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885782
Specimen Label: UC Davis_1885782
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885814
Specimen Label: UC Davis_1885814
Detected: true
Specimen Num: 42
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885815
Specimen Label: UC Davis_1885815
Detected: true
Specimen Num: 43
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885767
Specimen Label: UC Davis_1885767
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885768
Specimen Label: UC Davis_1885768
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885788
Specimen Label: UC Davis_1885788
Detected: true
Specimen Num: 19
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Publication
20537150 | J:161595
 
First Author: Mulugeta Achame E
Year: 2010
Journal: BMC Genomics
Title: The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids.
Volume: 11
Pages: 367
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Publication
32868078 | J:304697
First Author: Ma Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Loss of RAD6B induces degeneration of the cochlea in mice.
Volume: 531
Issue: 3
Pages: 402-408
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Publication
11689692 | J:72859
First Author: Kwon YT
Year: 2001
Journal: Mol Cell Biol
Title: Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway.
Volume: 21
Issue: 23
Pages: 8007-21
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Publication
12098698 | J:77750
First Author: Kwon YT
Year: 2002
Journal: Science
Title: An essential role of N-terminal arginylation in cardiovascular development.
Volume: 297
Issue: 5578
Pages: 96-9
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Publication
19008229 | J:145887
First Author: Tasaki T
Year: 2009
Journal: J Biol Chem
Title: The substrate recognition domains of the N-end rule pathway.
Volume: 284
Issue: 3
Pages: 1884-95
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Publication
22670058 | J:187008
First Author: Piatkov KI
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments.
Volume: 109
Issue: 27
Pages: E1839-47
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Publication
10805755 | J:62140
First Author: Kwon YT
Year: 2000
Journal: Mol Cell Biol
Title: Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway.
Volume: 20
Issue: 11
Pages: 4135-48
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Protein
Q6WKZ8
Organism: Mus musculus/domesticus
Length: 1755  
Fragment?: false
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q6WKZ8-2
Organism: Mus musculus/domesticus
Length: 1755  
Fragment?: false
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Protein
Q6WKZ8-3
Organism: Mus musculus/domesticus
Length: 1558  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 2
Description: E3 ubiquitin-protein ligase UBR2
Type: chain
End: 1755
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GO Term
GO:1990305 | RAD6-UBR2 ubiquitin ligase complex
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Publication
15548684 | -
First Author: Kwak KS
Year: 2004
Journal: Cancer Res
Title: Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia.
Volume: 64
Issue: 22
Pages: 8193-8
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Publication
15317757 | -
First Author: Yin J
Year: 2004
Journal: Hum Mol Genet
Title: RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway.
Volume: 13
Issue: 20
Pages: 2421-30
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Publication
30872531 | -
First Author: Chui AJ
Year: 2019
Journal: Science
Title: N-terminal degradation activates the NLRP1B inflammasome.
Volume: 364
Issue: 6435
Pages: 82-85
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Publication
17462990 | J:123383
First Author: Tasaki T
Year: 2007
Journal: J Biol Chem
Title: Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems.
Volume: 282
Issue: 25
Pages: 18510-20
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HT Experiment
E-GEOD-18824 | Expression data from 17 day old testes of wild type and UBR2-/- mice
Series Id: GSE18824
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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GO Term
GO:1990304 | MUB1-RAD6-UBR2 ubiquitin ligase complex
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Publication
26383956 | -
First Author: Zanet J
Year: 2015
Journal: Science
Title: Pri sORF peptides induce selective proteasome-mediated protein processing.
Volume: 349
Issue: 6254
Pages: 1356-8
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Protein Domain
IPR039164 | UBR1-like
Type: Family
Description: This entry represents a group of E3 ubiquitin-protein ligases, including UBR1, UBR2 and UBR3. They are part of the N-end rule pathway []. They recognize and bind to proteins bearing specific N-terminal residues, leading to their ubiquitination and subsequent degradation [, ].The UBR1 protein was shown to bind specifically to proteins bearing N-terminalresidues that are destabilising according to the N-end rule, but not tootherwise identical proteins bearing stabilising N-terminal residues []. UBR1 contains an N-terminal conserved region (the UBR-type zinc finger) which is also found in various proteins implicated in N-degron recognition [].
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Publication
30705122 | J:274204
First Author: Sin TK
Year: 2019
Journal: Cancer Res
Title: p300 Mediates Muscle Wasting in Lewis Lung Carcinoma.
Volume: 79
Issue: 7
Pages: 1331-1342
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Publication
30157281 | J:265502
First Author: Kim ST
Year: 2018
Journal: PLoS One
Title: The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins.
Volume: 13
Issue: 8
Pages: e0202260
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Protein
B7ZNW2
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
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Protein
A0A286YCB2
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: false
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Protein
F6RDS0
Organism: Mus musculus/domesticus
Length: 517  
Fragment?: true
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Protein
Q8CAW0
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
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Publication
10581257 | -
First Author: Xie Y
Year: 1999
Journal: EMBO J
Title: The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.
Volume: 18
Issue: 23
Pages: 6832-44
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Publication
29362488 | J:313570
First Author: Wang H
Year: 2018
Journal: Cell Death Dis
Title: Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice.
Volume: 9
Issue: 2
Pages: 76
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Publication
27195754 | -
First Author: Li T
Year: 2016
Journal: PLoS Genet
Title: Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.
Volume: 12
Issue: 5
Pages: e1006054
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Protein
B3DFI9
Organism: Mus musculus/domesticus
Length: 950  
Fragment?: true
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Protein
A2AV05
Organism: Mus musculus/domesticus
Length: 242  
Fragment?: true
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Protein
Q5U430
Organism: Mus musculus/domesticus
Length: 1889  
Fragment?: false
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Protein
F6QC57
Organism: Mus musculus/domesticus
Length: 1892  
Fragment?: false
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Protein
Q3TKQ2
Organism: Mus musculus/domesticus
Length: 849  
Fragment?: true
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Protein
Q497M7
Organism: Mus musculus/domesticus
Length: 859  
Fragment?: true
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Protein
Q3V1R9
Organism: Mus musculus/domesticus
Length: 850  
Fragment?: true
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Protein
O70481
Organism: Mus musculus/domesticus
Length: 1757  
Fragment?: false
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Protein
Q3UHE0
Organism: Mus musculus/domesticus
Length: 1755  
Fragment?: false
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Protein
Q3UPU3
Organism: Mus musculus/domesticus
Length: 1755  
Fragment?: false
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Protein
Q2M4I1
Organism: Mus musculus/domesticus
Length: 1757  
Fragment?: false
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Publication
12693553 | J:83413
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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