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Search results 901 to 1000 out of 2570 for Kras

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Category: Publication
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Type Details Score
Publication
25664850 | J:220549
First Author: Chen Y
Year: 2015
Journal: J Clin Invest
Title: Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma.
Volume: 125
Issue: 3
Pages: 1147-62
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Publication
37494452 | J:338531
First Author: Reyes-Castro RA
Year: 2023
Journal: Sci Adv
Title: Phosphorylated nuclear DICER1 promotes open chromatin state and lineage plasticity of AT2 tumor cells in lung adenocarcinomas.
Volume: 9
Issue: 30
Pages: eadf6210
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Publication
23913633 | J:211986
First Author: Belmont L
Year: 2014
Journal: Int J Cancer
Title: Expression of TLR9 in tumor-infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer.
Volume: 134
Issue: 4
Pages: 765-77
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Publication
20086246 | J:161573
First Author: Zaslavsky A
Year: 2010
Journal: Blood
Title: Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis.
Volume: 115
Issue: 22
Pages: 4605-13
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Publication
8944028 | J:36997
First Author: Fijneman RJ
Year: 1996
Journal: Nat Genet
Title: Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse.
Volume: 14
Issue: 4
Pages: 465-7
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Publication
7813906 | J:21801
First Author: Festing MF
Year: 1994
Journal: Genet Res
Title: At least four genes and sex are associated with susceptibility to urethane-induced pulmonary adenomas in mice.
Volume: 64
Issue: 2
Pages: 99-106
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Publication
24743474 | J:215194
First Author: Dow LE
Year: 2014
Journal: PLoS One
Title: Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.
Volume: 9
Issue: 4
Pages: e95236
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Publication
25301067 | J:258859
First Author: Terry MR
Year: 2015
Journal: Cell Death Differ
Title: Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo.
Volume: 22
Issue: 5
Pages: 719-30
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Publication
20975663 | J:167639
First Author: Sjogren AK
Year: 2011
Journal: Leukemia
Title: Inactivating GGTase-I reduces disease phenotypes in a mouse model of K-RAS-induced myeloproliferative disease.
Volume: 25
Issue: 1
Pages: 186-9
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Publication
19710506 | J:153839
First Author: Cutts BA
Year: 2009
Journal: Blood
Title: Nf1 deficiency cooperates with oncogenic K-RAS to induce acute myeloid leukemia in mice.
Volume: 114
Issue: 17
Pages: 3629-32
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Publication
29792386 | J:275033
First Author: Jamalpour M
Year: 2018
Journal: Tumour Biol
Title: Disparate effects of Shb gene deficiency on disease characteristics in murine models of myeloid, B-cell, and T-cell leukemia.
Volume: 40
Issue: 4
Pages: 1010428318771472
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Publication
28691711 | J:250331
 
First Author: Huang J
Year: 2017
Journal: Nat Commun
Title: Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.
Volume: 8
Pages: 15999
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Publication
21555567 | J:171896
First Author: Shaw AT
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress.
Volume: 108
Issue: 21
Pages: 8773-8
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Publication
34644378 | J:317338
First Author: Hasebe K
Year: 2021
Journal: Carcinogenesis
Title: Trefoil factor family 2 inhibits cholangiocarcinogenesis by regulating the PTEN pathway in mice.
Volume: 42
Issue: 12
Pages: 1496-1505
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Publication
15665300 | J:95509
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes.
Volume: 65
Issue: 1
Pages: 236-45
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Publication
15805275 | J:97360
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors.
Volume: 65
Issue: 7
Pages: 2755-60
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Publication
20876733 | J:164880
First Author: Lee DY
Year: 2010
Journal: Genes Dev
Title: Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner.
Volume: 24
Issue: 20
Pages: 2317-29
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Publication
32641778 | J:295341
First Author: Beel S
Year: 2020
Journal: Nat Commun
Title: κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis.
Volume: 11
Issue: 1
Pages: 3409
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Publication
21335545 | J:170465
First Author: Symonds JM
Year: 2011
Journal: Cancer Res
Title: Protein kinase C δ is a downstream effector of oncogenic K-ras in lung tumors.
Volume: 71
Issue: 6
Pages: 2087-97
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Publication
24213573 | J:216273
First Author: Wang IC
Year: 2014
Journal: Oncogene
Title: Foxm1 transcription factor is required for the initiation of lung tumorigenesis by oncogenic Kras(G12D.).
Volume: 33
Issue: 46
Pages: 5391-6
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Publication
20081861 | J:157079
First Author: Houghton AM
Year: 2010
Journal: Nat Med
Title: Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth.
Volume: 16
Issue: 2
Pages: 219-23
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Publication
24667377 | J:259219
First Author: Sanchez-Laorden B
Year: 2014
Journal: Sci Signal
Title: BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling.
Volume: 7
Issue: 318
Pages: ra30
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Publication
26880805 | J:231612
First Author: Yan Y
Year: 2016
Journal: Cancer Res
Title: KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis.
Volume: 76
Issue: 8
Pages: 2419-31
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Publication
24148820 | J:206523
First Author: Abrigo M
Year: 2014
Journal: Carcinogenesis
Title: Impairing squamous differentiation by Klf4 deletion is sufficient to initiate tongue carcinoma development upon K-Ras activation in mice.
Volume: 35
Issue: 3
Pages: 662-9
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Publication
26113043 | J:250091
First Author: Yu T
Year: 2016
Journal: Cell Death Differ
Title: KLF4 regulates adult lung tumor-initiating cells and represses K-Ras-mediated lung cancer.
Volume: 23
Issue: 2
Pages: 207-15
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Publication
10871846 | J:62962
First Author: Ise K
Year: 2000
Journal: Oncogene
Title: Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis.
Volume: 19
Issue: 26
Pages: 2951-6
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Publication
27381829 | J:253760
 
First Author: Chiblak S
Year: 2016
Journal: Sci Rep
Title: K-Ras and cyclooxygenase-2 coactivation augments intraductal papillary mucinous neoplasm and Notch1 mimicking human pancreas lesions.
Volume: 6
Pages: 29455
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Publication
23536795 | J:200177
First Author: Tapfer A
Year: 2013
Journal: PLoS One
Title: X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model.
Volume: 8
Issue: 3
Pages: e58439
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Publication
21084261 | J:168599
First Author: Mohammed A
Year: 2010
Journal: Cancer Prev Res (Phila)
Title: The epidermal growth factor receptor inhibitor gefitinib prevents the progression of pancreatic lesions to carcinoma in a conditional LSL-KrasG12D/+ transgenic mouse model.
Volume: 3
Issue: 11
Pages: 1417-26
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Publication
31100067 | J:277221
First Author: Hao F
Year: 2019
Journal: PLoS One
Title: Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice.
Volume: 14
Issue: 5
Pages: e0216603
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Publication
31114758 | J:281850
 
First Author: Dréau D
Year: 2019
Journal: Front Oncol
Title: Combining the Specific Anti-MUC1 Antibody TAB004 and Lip-MSA-IL-2 Limits Pancreatic Cancer Progression in Immune Competent Murine Models of Pancreatic Ductal Adenocarcinoma.
Volume: 9
Pages: 330
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Publication
29121082 | J:252764
First Author: Veite-Schmahl MJ
Year: 2017
Journal: PLoS One
Title: The Mouse Model of Pancreatic Cancer Atlas (MMPCA) for classification of pancreatic cancer lesions: A large histological investigation of the Ptf1aCre/+;LSL-KrasG12D/+ transgenic mouse model of pancreatic cancer.
Volume: 12
Issue: 11
Pages: e0187552
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25923219 | J:221104
 
First Author: LaConti JJ
Year: 2015
Journal: BMC Genomics
Title: Distinct serum metabolomics profiles associated with malignant progression in the KrasG12D mouse model of pancreatic ductal adenocarcinoma.
Volume: 16 Suppl 1
Pages: S1
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21738581 | J:174427
First Author: LaConti JJ
Year: 2011
Journal: PLoS One
Title: Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer.
Volume: 6
Issue: 6
Pages: e20687
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Publication
28697176 | J:309128
First Author: Veite-Schmahl MJ
Year: 2017
Journal: Br J Cancer
Title: HMGA1 expression levels are elevated in pancreatic intraepithelial neoplasia cells in the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.
Volume: 117
Issue: 5
Pages: 639-647
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31068602 | J:279841
First Author: Leal AS
Year: 2019
Journal: Sci Rep
Title: The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice.
Volume: 9
Issue: 1
Pages: 7072
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28698299 | J:244541
First Author: Mello SS
Year: 2017
Journal: Genes Dev
Title: Neat1 is a p53-inducible lincRNA essential for transformation suppression.
Volume: 31
Issue: 11
Pages: 1095-1108
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29713060 | J:264005
First Author: Handler J
Year: 2018
Journal: Oncogene
Title: Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-β exposure.
Volume: 37
Issue: 31
Pages: 4334-4342
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Publication
28419443 | J:250518
First Author: Janakiram NB
Year: 2017
Journal: Immunology
Title: Loss of natural killer T cells promotes pancreatic cancer in LSL-KrasG12D/+ mice.
Volume: 152
Issue: 1
Pages: 36-51
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Publication
24466367 | J:264441
First Author: Mohammed A
Year: 2013
Journal: Transl Oncol
Title: Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling.
Volume: 6
Issue: 6
Pages: 649-59
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Publication
23019409 | J:232014
First Author: Rao CV
Year: 2012
Journal: Neoplasia
Title: Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice.
Volume: 14
Issue: 9
Pages: 778-87
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Publication
30016349 | J:264100
First Author: Schmahl MJ
Year: 2018
Journal: PLoS One
Title: NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.
Volume: 13
Issue: 7
Pages: e0200658
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Publication
23308056 | J:195077
First Author: Mohammed A
Year: 2012
Journal: Neoplasia
Title: Endogenous n-3 polyunsaturated fatty acids delay progression of pancreatic ductal adenocarcinoma in Fat-1-p48(Cre/+)-LSL-Kras(G12D/+) mice.
Volume: 14
Issue: 12
Pages: 1249-59
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Publication
19109152 | J:143039
First Author: Mukherjee P
Year: 2009
Journal: J Immunol
Title: Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition.
Volume: 182
Issue: 1
Pages: 216-24
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Publication
22287227 | J:187865
First Author: Mohammed A
Year: 2012
Journal: Int J Cancer
Title: Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice.
Volume: 131
Issue: 8
Pages: 1951-62
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Publication
17909062 | J:125575
First Author: Clark CE
Year: 2007
Journal: Cancer Res
Title: Dynamics of the immune reaction to pancreatic cancer from inception to invasion.
Volume: 67
Issue: 19
Pages: 9518-27
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34385181 | J:311805
First Author: Wang X
Year: 2021
Journal: Cancer Res
Title: Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11.
Volume: 81
Issue: 20
Pages: 5217-5229
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Publication
28548087 | J:249686
 
First Author: Goodwin J
Year: 2017
Journal: Nat Commun
Title: The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.
Volume: 8
Pages: 15503
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Publication
31666695 | J:287508
First Author: Momcilovic M
Year: 2019
Journal: Nature
Title: In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer.
Volume: 575
Issue: 7782
Pages: 380-384
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Publication
35941104 | J:327227
First Author: Queiroz AL
Year: 2022
Journal: Nat Commun
Title: Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer.
Volume: 13
Issue: 1
Pages: 4633
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Publication
25042806 | J:215610
First Author: Goodwin JM
Year: 2014
Journal: Mol Cell
Title: An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.
Volume: 55
Issue: 3
Pages: 436-50
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24086281 | J:207525
First Author: Nakada Y
Year: 2013
Journal: PLoS One
Title: The LKB1 tumor suppressor as a biomarker in mouse and human tissues.
Volume: 8
Issue: 9
Pages: e73449
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24174333 | J:211968
First Author: Jin Y
Year: 2014
Journal: Int J Cancer
Title: NEDD9 promotes lung cancer metastasis through epithelial-mesenchymal transition.
Volume: 134
Issue: 10
Pages: 2294-304
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25011082 | J:214235
First Author: Inge LJ
Year: 2014
Journal: Cancer Lett
Title: LKB1 inactivation sensitizes non-small cell lung cancer to pharmacological aggravation of ER stress.
Volume: 352
Issue: 2
Pages: 187-95
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28284717 | J:241935
First Author: Hou S
Year: 2017
Journal: Am J Pathol
Title: Evidence, Mechanism, and Clinical Relevance of the Transdifferentiation from Lung Adenocarcinoma to Squamous Cell Carcinoma.
Volume: 187
Issue: 5
Pages: 954-962
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27893707 | J:243057
First Author: Miller A
Year: 2017
Journal: Oncogene
Title: Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma.
Volume: 36
Issue: 21
Pages: 3059-3066
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Publication
37258742 | J:338804
First Author: Zhong H
Year: 2023
Journal: Oncogene
Title: SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity.
Volume: 42
Issue: 27
Pages: 2183-2194
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Publication
22792269 | J:189508
First Author: Sabbir MG
Year: 2012
Journal: PLoS One
Title: The role of Dlc1 isoform 2 in K-Ras2(G12D) induced thymic cancer.
Volume: 7
Issue: 7
Pages: e40302
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29632194 | J:261483
First Author: Wu Q
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.
Volume: 115
Issue: 17
Pages: E3978-E3986
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33608386 | J:307162
     
First Author: Cai H
Year: 2021
Journal: Cancer Discov
Title: A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer.
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Publication
29133460 | J:261632
 
First Author: Peng W
Year: 2018
Journal: Mol Cell Biol
Title: Elevated HuR in Pancreas Promotes a Pancreatitis-Like Inflammatory Microenvironment That Facilitates Tumor Development.
Volume: 38
Issue: 3
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23936539 | J:205769
First Author: Talluri S
Year: 2013
Journal: PLoS One
Title: Mutation of the LXCXE binding cleft of pRb facilitates transformation by ras in vitro but does not promote tumorigenesis in vivo.
Volume: 8
Issue: 8
Pages: e72236
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21628592 | J:173311
First Author: Eser S
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging.
Volume: 108
Issue: 24
Pages: 9945-50
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29758119 | J:273924
First Author: Kurosawa K
Year: 2018
Journal: Cancer Sci
Title: Loss of protein phosphatase 6 in mouse keratinocytes enhances K-rasG12D -driven tumor promotion.
Volume: 109
Issue: 7
Pages: 2178-2187
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Publication
24355609 | J:211965
First Author: Snippert HJ
Year: 2014
Journal: EMBO Rep
Title: Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion.
Volume: 15
Issue: 1
Pages: 62-9
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32908137 | J:297251
First Author: Schlesinger Y
Year: 2020
Journal: Nat Commun
Title: Single-cell transcriptomes of pancreatic preinvasive lesions and cancer reveal acinar metaplastic cells' heterogeneity.
Volume: 11
Issue: 1
Pages: 4516
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17114586 | J:116111
First Author: Pasca di Magliano M
Year: 2006
Journal: Genes Dev
Title: Hedgehog/Ras interactions regulate early stages of pancreatic cancer.
Volume: 20
Issue: 22
Pages: 3161-73
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28249896 | J:242071
First Author: Gomez-Chou SB
Year: 2017
Journal: Cancer Res
Title: Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment.
Volume: 77
Issue: 10
Pages: 2647-2660
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27670082 | J:299420
First Author: Matsuo J
Year: 2017
Journal: Gastroenterology
Title: Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice.
Volume: 152
Issue: 1
Pages: 218-231.e14
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31619584 | J:297309
 
First Author: Speth JM
Year: 2019
Journal: JCI Insight
Title: Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics.
Volume: 4
Issue: 20
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Publication
26220524 | J:224440
 
First Author: Russell R
Year: 2015
Journal: Nat Commun
Title: Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.
Volume: 6
Pages: 7677
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Publication
30451898 | J:269952
First Author: Santofimia-Castaño P
Year: 2018
Journal: Sci Rep
Title: Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis.
Volume: 8
Issue: 1
Pages: 16999
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Publication
37337025 | J:336916
First Author: Whitt AG
Year: 2023
Journal: Sci Rep
Title: Paraoxonase 2 (PON2) plays a limited role in murine lung tumorigenesis.
Volume: 13
Issue: 1
Pages: 9929
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Publication
23852374 | J:228608
First Author: Evangelou K
Year: 2013
Journal: Cell Death Differ
Title: The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis.
Volume: 20
Issue: 11
Pages: 1485-97
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Publication
22857000 | J:316957
 
First Author: Nallapalli RK
Year: 2012
Journal: Mol Cancer
Title: Targeting filamin A reduces K-RAS-induced lung adenocarcinomas and endothelial response to tumor growth in mice.
Volume: 11
Pages: 50
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20639455 | J:163466
First Author: Meyer SE
Year: 2010
Journal: Am J Pathol
Title: Kruppel-like factor 5 is not required for K-RasG12D lung tumorigenesis, but represses ABCG2 expression and is associated with better disease-specific survival.
Volume: 177
Issue: 3
Pages: 1503-13
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34302028 | J:308632
First Author: Liot S
Year: 2021
Journal: Sci Rep
Title: Development of thymic tumor in [LSL:KrasG12D; Pdx1-CRE] mice, an adverse effect associated with accelerated pancreatic carcinogenesis.
Volume: 11
Issue: 1
Pages: 15075
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17804720 | J:124883
First Author: Kissil JL
Year: 2007
Journal: Cancer Res
Title: Requirement for Rac1 in a K-ras induced lung cancer in the mouse.
Volume: 67
Issue: 17
Pages: 8089-94
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22011581 | J:180053
First Author: Gao Q
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression.
Volume: 108
Issue: 44
Pages: 18061-6
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Publication
23321669 | J:194493
First Author: Tzatsos A
Year: 2013
Journal: J Clin Invest
Title: KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs.
Volume: 123
Issue: 2
Pages: 727-39
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Publication
26294213 | J:224905
First Author: Zhong R
Year: 2015
Journal: Cancer Res
Title: Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Volume: 75
Issue: 18
Pages: 3958-3969
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Publication
23269246 | J:192593
First Author: Vernon PJ
Year: 2013
Journal: J Immunol
Title: The receptor for advanced glycation end products promotes pancreatic carcinogenesis and accumulation of myeloid-derived suppressor cells.
Volume: 190
Issue: 3
Pages: 1372-9
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Publication
35618180 | J:325602
 
First Author: Panda H
Year: 2022
Journal: Free Radic Biol Med
Title: Halofuginone micelle nanoparticles eradicate Nrf2-activated lung adenocarcinoma without systemic toxicity.
Volume: 187
Pages: 92-104
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Publication
28550040 | J:244285
First Author: Kamata T
Year: 2017
Journal: Blood
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