Type |
Details |
Score |
UniProt Feature |
Begin: |
30 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
30 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
128 |
Description: |
Phosphotyrosine; by Src |
Type: |
modified residue |
End: |
128 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
925 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
925 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
18 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
18 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
114 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
114 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
755 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
755 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
756 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
756 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
757 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
757 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
722 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
722 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
215 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
215 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
2 |
Description: |
Proto-oncogene tyrosine-protein kinase Src |
Type: |
chain |
End: |
535 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Src substrate cortactin |
Type: |
chain |
End: |
546 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
482 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
482 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
485 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
485 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Src kinase-associated phosphoprotein 2 |
Type: |
chain |
End: |
358 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Src kinase-associated phosphoprotein 1 |
Type: |
chain |
End: |
355 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
55 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
55 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
833 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
833 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
830 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
830 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
202 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
202 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
201 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
201 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
192 |
Description: |
Phosphotyrosine; by SRC |
Type: |
modified residue |
End: |
192 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Laughlin-Bunner B |
Year: |
2001 |
Journal: |
Blood |
Title: |
Lyn is required for normal stem cell factor-induced proliferation and chemotaxis of primary hematopoietic cells. |
Volume: |
98 |
Issue: |
2 |
Pages: |
343-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seykora JT |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
'Srcasm: a novel Src activating and signaling molecule. |
Volume: |
277 |
Issue: |
4 |
Pages: |
2812-22 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Kitaura J |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Dysregulation of Src family kinases in mast cells from epilepsy-resistant ASK versus epilepsy-prone EL mice. |
Volume: |
178 |
Issue: |
1 |
Pages: |
455-62 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
535
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Pathway |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu X |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate. |
Volume: |
286 |
Issue: |
35 |
Pages: |
30526-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Araujo J |
Year: |
2009 |
Journal: |
Int J Cancer |
Title: |
Targeting Src signaling in metastatic bone disease. |
Volume: |
124 |
Issue: |
1 |
Pages: |
1-6 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2005 |
Journal: |
Immunity |
Title: |
The Src family kinases Hck and Fgr negatively regulate neutrophil and dendritic cell chemokine signaling via PIR-B. |
Volume: |
22 |
Issue: |
2 |
Pages: |
235-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fumagalli L |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Class I phosphoinositide-3-kinases and SRC kinases play a nonredundant role in regulation of adhesion-independent and -dependent neutrophil reactive oxygen species generation. |
Volume: |
190 |
Issue: |
7 |
Pages: |
3648-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alexandropoulos K |
Year: |
1995 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Proline-rich sequences that bind to Src homology 3 domains with individual specificities. |
Volume: |
92 |
Issue: |
8 |
Pages: |
3110-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Y |
Year: |
2005 |
Journal: |
Immunity |
Title: |
Lyn tyrosine kinase: accentuating the positive and the negative. |
Volume: |
22 |
Issue: |
1 |
Pages: |
9-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tehrani S |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Src phosphorylation of cortactin enhances actin assembly. |
Volume: |
104 |
Issue: |
29 |
Pages: |
11933-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
541
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhan X |
Year: |
1993 |
Journal: |
J Biol Chem |
Title: |
Murine cortactin is phosphorylated in response to fibroblast growth factor-1 on tyrosine residues late in the G1 phase of the BALB/c 3T3 cell cycle. |
Volume: |
268 |
Issue: |
32 |
Pages: |
24427-31 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
126
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
97
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
165
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
126
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
78
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka M |
Year: |
2016 |
Journal: |
Cancer Res |
Title: |
SKAP2 Promotes Podosome Formation to Facilitate Tumor-Associated Macrophage Infiltration and Metastatic Progression. |
Volume: |
76 |
Issue: |
2 |
Pages: |
358-69 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thomas RM |
Year: |
2004 |
Journal: |
Immunity |
Title: |
C-terminal SRC kinase controls acute inflammation and granulocyte adhesion. |
Volume: |
20 |
Issue: |
2 |
Pages: |
181-91 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Zarbock A |
Year: |
2008 |
Journal: |
J Exp Med |
Title: |
PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling. |
Volume: |
205 |
Issue: |
10 |
Pages: |
2339-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pleiman CM |
Year: |
1993 |
Journal: |
Mol Cell Biol |
Title: |
Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase. |
Volume: |
13 |
Issue: |
9 |
Pages: |
5877-87 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Franco M |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors. |
Volume: |
26 |
Issue: |
5 |
Pages: |
1932-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khadaroo RG |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Oxidative stress reprograms lipopolysaccharide signaling via Src kinase-dependent pathway in RAW 264.7 macrophage cell line. |
Volume: |
278 |
Issue: |
48 |
Pages: |
47834-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sekimoto H |
Year: |
2003 |
Journal: |
Endocrinology |
Title: |
C-terminal Src kinase (CSK) modulates insulin-like growth factor-I signaling through Src in 3T3-L1 differentiation. |
Volume: |
144 |
Issue: |
6 |
Pages: |
2546-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Laird RM |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Unexpected role for the B cell-specific Src family kinase B lymphoid kinase in the development of IL-17-producing γδ T cells. |
Volume: |
185 |
Issue: |
11 |
Pages: |
6518-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Endele M |
Year: |
2017 |
Journal: |
Blood |
Title: |
CSF-1-induced Src signaling can instruct monocytic lineage choice. |
Volume: |
129 |
Issue: |
12 |
Pages: |
1691-1701 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishizumi H |
Year: |
1997 |
Journal: |
J Immunol |
Title: |
Impaired tyrosine phosphorylation and Ca2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells. |
Volume: |
158 |
Issue: |
5 |
Pages: |
2350-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chu CL |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
The Lyn tyrosine kinase differentially regulates dendritic cell generation and maturation. |
Volume: |
175 |
Issue: |
5 |
Pages: |
2880-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ayoub E |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Regulation of the Src kinase-associated phosphoprotein 55 homologue by the protein tyrosine phosphatase PTP-PEST in the control of cell motility. |
Volume: |
288 |
Issue: |
36 |
Pages: |
25739-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abe K |
Year: |
2006 |
Journal: |
Mamm Genome |
Title: |
New ENU-induced semidominant mutation, Ali18, causes inflammatory arthritis, dermatitis, and osteoporosis in the mouse. |
Volume: |
17 |
Issue: |
9 |
Pages: |
915-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abe K |
Year: |
2009 |
Journal: |
Mamm Genome |
Title: |
Genome-wide search for genes that modulate inflammatory arthritis caused by Ali18 mutation in mice. |
Volume: |
20 |
Issue: |
3 |
Pages: |
152-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhong X |
Year: |
2019 |
Journal: |
MGI Direct Data Submission |
Title: |
Mutagenetix entry for water. |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
542 |
Description: |
Phosphotyrosine; by SRC and autocatalysis |
Type: |
modified residue |
End: |
542 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
284 |
Description: |
Phosphotyrosine; by SRC and autocatalysis |
Type: |
modified residue |
End: |
284 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
376 |
Description: |
Phosphotyrosine; by SRC and INSR |
Type: |
modified residue |
End: |
376 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
379 |
Description: |
Phosphotyrosine; by SRC and INSR |
Type: |
modified residue |
End: |
379 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
9 |
Description: |
Phosphotyrosine; by SRC and INSR |
Type: |
modified residue |
End: |
9 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
604 |
Description: |
Interaction with SRC and ESR1 |
Type: |
short sequence motif |
End: |
607 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
25 |
Description: |
Phosphotyrosine; by SRC and HCK |
Type: |
modified residue |
End: |
25 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
740 |
Description: |
Phosphotyrosine; by SRC and autocatalysis |
Type: |
modified residue |
End: |
740 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
739 |
Description: |
Phosphotyrosine; by SRC and autocatalysis |
Type: |
modified residue |
End: |
739 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
735 |
Description: |
Phosphotyrosine; by SRC and autocatalysis |
Type: |
modified residue |
End: |
735 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
471 |
Description: |
Phosphotyrosine; by SRC and autocatalysis |
Type: |
modified residue |
End: |
471 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
577 |
Description: |
Phosphotyrosine; by RET and SRC |
Type: |
modified residue |
End: |
577 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
576 |
Description: |
Phosphotyrosine; by RET and SRC |
Type: |
modified residue |
End: |
576 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
SRC kinase signaling inhibitor 1 |
Type: |
chain |
End: |
1250 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
452 |
Description: |
Phosphotyrosine; by ABL1 and SRC |
Type: |
modified residue |
End: |
452 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1063 |
Description: |
Phosphotyrosine; by autocatalysis and SRC |
Type: |
modified residue |
End: |
1063 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1333 |
Description: |
Phosphotyrosine; by autocatalysis and SRC |
Type: |
modified residue |
End: |
1333 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1337 |
Description: |
Phosphotyrosine; by autocatalysis and SRC |
Type: |
modified residue |
End: |
1337 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frame MC |
Year: |
2002 |
Journal: |
Biochim Biophys Acta |
Title: |
Src in cancer: deregulation and consequences for cell behaviour. |
Volume: |
1602 |
Issue: |
2 |
Pages: |
114-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Groveman BR |
Year: |
2012 |
Journal: |
FEBS J |
Title: |
The regulation of N-methyl-D-aspartate receptors by Src kinase. |
Volume: |
279 |
Issue: |
1 |
Pages: |
20-8 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsuda M |
Year: |
2008 |
Journal: |
Glia |
Title: |
Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury. |
Volume: |
56 |
Issue: |
1 |
Pages: |
50-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishizumi H |
Year: |
1995 |
Journal: |
Immunity |
Title: |
Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice. |
Volume: |
3 |
Issue: |
5 |
Pages: |
549-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li X |
Year: |
2014 |
Journal: |
Eur J Immunol |
Title: |
Lyn regulates inflammatory responses in Klebsiella pneumoniae infection via the p38/NF-κB pathway. |
Volume: |
44 |
Issue: |
3 |
Pages: |
763-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han J |
Year: |
2013 |
Journal: |
Blood |
Title: |
A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. |
Volume: |
122 |
Issue: |
25 |
Pages: |
4140-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Du C |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Increased severity of experimental allergic encephalomyelitis in lyn-/- mice in the absence of elevated proinflammatory cytokine response in the central nervous system. |
Volume: |
168 |
Issue: |
6 |
Pages: |
3105-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gibb SL |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Lyn kinase regulates mesolimbic dopamine release: implication for alcohol reward. |
Volume: |
31 |
Issue: |
6 |
Pages: |
2180-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miki S |
Year: |
2001 |
Journal: |
Genes Cells |
Title: |
Reduction of atherosclerosis despite hypercholesterolemia in lyn-deficient mice fed a high-fat diet. |
Volume: |
6 |
Issue: |
1 |
Pages: |
37-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Umemori H |
Year: |
2003 |
Journal: |
Neuroscience |
Title: |
Impairment of N-methyl-D-aspartate receptor-controlled motor activity in LYN-deficient mice. |
Volume: |
118 |
Issue: |
3 |
Pages: |
709-13 |
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Publication |
First Author: |
Schneider H |
Year: |
2008 |
Journal: |
PLoS One |
Title: |
Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells. |
Volume: |
3 |
Issue: |
3 |
Pages: |
e1718 |
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Publication |
First Author: |
Fiedler A |
Year: |
2014 |
Journal: |
Behav Brain Res |
Title: |
Hippocampus-dependent learning in SKAP-HOM deficient mice. |
Volume: |
270 |
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Pages: |
125-30 |
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Publication |
First Author: |
Nguyen GT |
Year: |
2021 |
Journal: |
iScience |
Title: |
Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation. |
Volume: |
24 |
Issue: |
8 |
Pages: |
102871 |
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Publication |
First Author: |
Chan VW |
Year: |
1998 |
Journal: |
Curr Biol |
Title: |
Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes. |
Volume: |
8 |
Issue: |
10 |
Pages: |
545-53 |
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Publication |
First Author: |
Subramanian A |
Year: |
2006 |
Journal: |
Leuk Res |
Title: |
Mutation of the Lyn tyrosine kinase delays the progression of Friend virus induced erythroleukemia without affecting susceptibility. |
Volume: |
30 |
Issue: |
9 |
Pages: |
1141-9 |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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