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Search results 1501 to 1600 out of 7122 for App

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Type Details Score
Publication
24916066 | J:310292
 
First Author: Niedowicz DM
Year: 2014
Journal: Acta Neuropathol Commun
Title: Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia.
Volume: 2
Pages: 64
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Publication
31034991 | J:277797
First Author: Zhang L
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: The db mutation improves memory in younger mice in a model of Alzheimer's disease.
Volume: 1865
Issue: 9
Pages: 2157-2167
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Publication
22514046 | J:188080
First Author: Drummond ES
Year: 2012
Journal: Endocrinology
Title: Altered expression of Alzheimer's disease-related proteins in male hypogonadal mice.
Volume: 153
Issue: 6
Pages: 2789-99
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Publication
24865997 | J:328489
First Author: Muradashvili N
Year: 2014
Journal: J Cereb Blood Flow Metab
Title: Ablation of MMP9 gene ameliorates paracellular permeability and fibrinogen-amyloid beta complex formation during hyperhomocysteinemia.
Volume: 34
Issue: 9
Pages: 1472-82
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Publication
30127003 | J:265540
First Author: Tzeng TC
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.
Volume: 115
Issue: 36
Pages: 9002-9007
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Publication
22383525 | J:241474
First Author: Basak JM
Year: 2012
Journal: J Biol Chem
Title: Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes.
Volume: 287
Issue: 17
Pages: 13959-71
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Publication
17626125 | J:124699
First Author: Bearden SE
Year: 2007
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Advancing age produces sex differences in vasomotor kinetics during and after skeletal muscle contraction.
Volume: 293
Issue: 3
Pages: R1274-9
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Publication
27563063 | J:237291
First Author: Beraldo FH
Year: 2016
Journal: J Biol Chem
Title: Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex.
Volume: 291
Issue: 42
Pages: 21945-21955
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Publication
16377636 | J:108326
First Author: Tanemura K
Year: 2006
Journal: J Biol Chem
Title: Formation of tau inclusions in knock-in mice with familial Alzheimer disease (FAD) mutation of presenilin 1 (PS1).
Volume: 281
Issue: 8
Pages: 5037-41
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Publication
15778722 | J:97539
First Author: Saito T
Year: 2005
Journal: Nat Med
Title: Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation.
Volume: 11
Issue: 4
Pages: 434-9
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Publication
33239400 | J:300750
First Author: George AA
Year: 2021
Journal: J Neurosci
Title: Implications of Oligomeric Amyloid-Beta (oAβ42) Signaling through α7β2-Nicotinic Acetylcholine Receptors (nAChRs) on Basal Forebrain Cholinergic Neuronal Intrinsic Excitability and Cognitive Decline.
Volume: 41
Issue: 3
Pages: 555-575
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Publication
- | J:322668
     
First Author: De Schepper S
Year: 2022
Journal: bioRxiv
Title: Perivascular SPP1 Mediates Microglial Engulfment of Synapses in Alzheimer's Disease Models
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Publication
28384478 | J:256145
First Author: Temkin P
Year: 2017
Journal: Neuron
Title: The Retromer Supports AMPA Receptor Trafficking During LTP.
Volume: 94
Issue: 1
Pages: 74-82.e5
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Publication
28877993 | J:245230
First Author: Qu X
Year: 2017
Journal: J Cell Biol
Title: Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity.
Volume: 216
Issue: 10
Pages: 3161-3178
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Publication
37585286 | J:342467
First Author: Shiraki Y
Year: 2023
Journal: Mol Biol Cell
Title: Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1.
Volume: 34
Issue: 11
Pages: ar110
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Publication
15345711 | J:94484
First Author: Beglopoulos V
Year: 2004
Journal: J Biol Chem
Title: Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice.
Volume: 279
Issue: 45
Pages: 46907-14
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Publication
28500862 | J:243583
First Author: Bennett RE
Year: 2017
Journal: Am J Pathol
Title: Enhanced Tau Aggregation in the Presence of Amyloid β.
Volume: 187
Issue: 7
Pages: 1601-1612
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Publication
36990365 | J:346892
 
First Author: Pedersen TJ
Year: 2023
Journal: Neurobiol Dis
Title: The effect of aquaporin-4 mis-localization on Aβ deposition in mice.
Volume: 181
Pages: 106100
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Publication
23831373 | J:327393
First Author: Wu Z
Year: 2013
Journal: Neurobiol Aging
Title: Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia.
Volume: 34
Issue: 12
Pages: 2715-25
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Publication
33296651 | J:299265
First Author: Zou C
Year: 2020
Journal: Cell Rep
Title: Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer's Disease.
Volume: 33
Issue: 10
Pages: 108447
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Publication
29274751 | J:271785
 
First Author: Moriguchi S
Year: 2018
Journal: Neuropharmacology
Title: Reduced expression of Na+/Ca2+ exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice.
Volume: 131
Pages: 291-303
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Publication
31160584 | J:278451
First Author: Hashimoto S
Year: 2019
Journal: Nat Commun
Title: Tau binding protein CAPON induces tau aggregation and neurodegeneration.
Volume: 10
Issue: 1
Pages: 2394
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Publication
12514215 | J:81203
First Author: Brich J
Year: 2003
Journal: J Neurosci
Title: Genetic modulation of tau phosphorylation in the mouse.
Volume: 23
Issue: 1
Pages: 187-92
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Publication
39639016 | J:361232
First Author: Baligács N
Year: 2024
Journal: Nat Commun
Title: Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer's Disease.
Volume: 15
Issue: 1
Pages: 10634
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Publication
25851535 | J:233407
First Author: Li C
Year: 2015
Journal: EMBO Mol Med
Title: ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy.
Volume: 7
Issue: 6
Pages: 754-69
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Publication
16549802 | J:107636
First Author: Monsonego A
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease.
Volume: 103
Issue: 13
Pages: 5048-53
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Publication
21113149 | J:167228
First Author: Cissé M
Year: 2011
Journal: Nature
Title: Reversing EphB2 depletion rescues cognitive functions in Alzheimer model.
Volume: 469
Issue: 7328
Pages: 47-52
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Publication
28205565 | J:272769
 
First Author: Criscuolo C
Year: 2017
Journal: Sci Rep
Title: Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer's disease mouse model.
Volume: 7
Pages: 42370
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Publication
37575021 | J:351099
First Author: Rueda-Carrasco J
Year: 2023
Journal: EMBO J
Title: Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.
Volume: 42
Issue: 19
Pages: e113246
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Publication
36670138 | J:333385
First Author: Hashimoto S
Year: 2023
Journal: Sci Rep
Title: Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation.
Volume: 13
Issue: 1
Pages: 1109
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Publication
29222348 | J:272127
 
First Author: Li H
Year: 2018
Journal: Biosci Rep
Title: Insulin degrading enzyme contributes to the pathology in a mixed model of Type 2 diabetes and Alzheimer's disease: possible mechanisms of IDE in T2D and AD.
Volume: 38
Issue: 1
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Publication
32392471 | J:301449
First Author: Sauerbeck AD
Year: 2020
Journal: Neuron
Title: SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury.
Volume: 107
Issue: 2
Pages: 257-273.e5
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Publication
29946028 | J:263855
First Author: Prasad H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH.
Volume: 115
Issue: 28
Pages: E6640-E6649
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Publication
38789405 | J:350542
First Author: Hashim KNB
Year: 2024
Journal: FEBS Lett
Title: Neuronal glutathione depletion elevates the Aβ42/Aβ40 ratio and tau aggregation in Alzheimer's disease mice.
Volume: 598
Issue: 13
Pages: 1576-1590
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Publication
8922407 | J:36884
First Author: Lee MK
Year: 1996
Journal: J Neurosci
Title: Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues.
Volume: 16
Issue: 23
Pages: 7513-25
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Publication
17727637 | J:126870
First Author: Mameza MG
Year: 2007
Journal: J Neurochem
Title: Characterization of the adaptor protein ARH expression in the brain and ARH molecular interactions.
Volume: 103
Issue: 3
Pages: 927-41
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Publication
27460146 | J:235288
 
First Author: Wang C
Year: 2016
Journal: Neurobiol Aging
Title: VPS35 regulates cell surface recycling and signaling of dopamine receptor D1.
Volume: 46
Pages: 22-31
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Publication
20876579 | J:268009
First Author: Tamboli IY
Year: 2010
Journal: J Biol Chem
Title: Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
Volume: 285
Issue: 48
Pages: 37405-14
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7736788 | J:26602
First Author: Habets GG
Year: 1995
Journal: Cytogenet Cell Genet
Title: The invasion-inducing TIAM1 gene maps to human chromosome band 21q22 and mouse chromosome 16.
Volume: 70
Issue: 1-2
Pages: 48-51
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Publication
8757628 | J:36436
First Author: Meda L
Year: 1996
Journal: J Immunol
Title: Beta-amyloid (25-35) peptide and IFN-gamma synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells.
Volume: 157
Issue: 3
Pages: 1213-8
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10353238 | J:55035
First Author: Haass C
Year: 1999
Journal: Nature
Title: Apoptosis. Dead end for neurodegeneration?
Volume: 399
Issue: 6733
Pages: 204-5, 207
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Publication
10356989 | J:57211
First Author: Sturchler-Pierrat C
Year: 1999
Journal: Rev Neurosci
Title: Transgenic animals in Alzheimer's disease research.
Volume: 10
Issue: 1
Pages: 15-24
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12070348 | J:77374
First Author: Xia X
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms.
Volume: 99
Issue: 13
Pages: 8760-5
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Publication
17130235 | J:118294
First Author: Bao J
Year: 2007
Journal: Mol Cell Biol
Title: Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65.
Volume: 27
Issue: 4
Pages: 1321-33
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Publication
19617540 | J:150950
First Author: Wang H
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility.
Volume: 106
Issue: 30
Pages: 12436-41
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Publication
26168040 | J:238377
First Author: Potter AS
Year: 2015
Journal: PLoS One
Title: Molecular Anatomy of Palate Development.
Volume: 10
Issue: 7
Pages: e0132662
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Publication
31551514 | J:298206
First Author: Guan PP
Year: 2019
Journal: Cell Mol Immunol
Title: Cyclooxygenase-2 is critical for the propagation of β-amyloid protein and reducing the glycosylation of tau in Alzheimer's disease.
Volume: 16
Issue: 11
Pages: 892-894
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Publication
33087587 | J:325261
First Author: Li J
Year: 2020
Journal: Aging (Albany NY)
Title: MicroRNA-338-5p alleviates neuronal apoptosis via directly targeting BCL2L11 in APP/PS1 mice.
Volume: 12
Issue: 20
Pages: 20728-20742
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Publication
- | J:14135
 
First Author: Guenet JL
Year: 1988
Journal: Mouse News Lett
Title: Changed gene symbols: Adap changed to App; Acetylcholine receptor symbol changes
Volume: 80
Pages: 5
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Publication
19005074 | J:142399
First Author: Tamboli IY
Year: 2008
Journal: J Neurosci
Title: Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Volume: 28
Issue: 46
Pages: 12097-106
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Publication
15944124 | J:100260
First Author: Pardossi-Piquard R
Year: 2005
Journal: Neuron
Title: Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP.
Volume: 46
Issue: 4
Pages: 541-54
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7542371 | J:25487
First Author: Lorent K
Year: 1995
Journal: Neuroscience
Title: Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein.
Volume: 65
Issue: 4
Pages: 1009-25
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Publication
19907078 | J:155100
First Author: Varvel NH
Year: 2009
Journal: J Clin Invest
Title: NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.
Volume: 119
Issue: 12
Pages: 3692-702
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Publication
11224536 | J:79847
First Author: Cai H
Year: 2001
Journal: Nat Neurosci
Title: BACE1 is the major beta-secretase for generation of Abeta peptides by neurons.
Volume: 4
Issue: 3
Pages: 233-4
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23831026 | J:200998
First Author: Hu X
Year: 2013
Journal: Cell Rep
Title: BACE1 regulates hippocampal astrogenesis via the Jagged1-Notch pathway.
Volume: 4
Issue: 1
Pages: 40-9
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Publication
22728825 | J:186413
First Author: Kuhn PH
Year: 2012
Journal: EMBO J
Title: Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons.
Volume: 31
Issue: 14
Pages: 3157-68
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18413858 | J:137970
First Author: Hu X
Year: 2008
Journal: FASEB J
Title: Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves.
Volume: 22
Issue: 8
Pages: 2970-80
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Publication
29716987 | J:325843
First Author: Herber J
Year: 2018
Journal: Mol Cell Proteomics
Title: Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome.
Volume: 17
Issue: 8
Pages: 1487-1501
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Publication
36810097 | J:335690
First Author: Müller SA
Year: 2023
Journal: Mol Neurodegener
Title: The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130.
Volume: 18
Issue: 1
Pages: 13
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Publication
17099708 | J:116162
First Author: Hu X
Year: 2006
Journal: Nat Neurosci
Title: Bace1 modulates myelination in the central and peripheral nervous system.
Volume: 9
Issue: 12
Pages: 1520-5
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Publication
25961820 | J:235334
First Author: Heindl M
Year: 2015
Journal: PLoS One
Title: Loss of Bace1 in mice does not alter the severity of caerulein induced pancreatitis.
Volume: 10
Issue: 5
Pages: e0125556
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Publication
28191691 | J:241878
First Author: Hu X
Year: 2017
Journal: Glia
Title: BACE1 regulates the proliferation and cellular functions of Schwann cells.
Volume: 65
Issue: 5
Pages: 712-726
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Publication
33548223 | J:305239
   
First Author: Kim W
Year: 2021
Journal: J Biol Chem
Title: Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo.
Pages: 100372
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Publication
24637500 | J:215109
First Author: Wang H
Year: 2014
Journal: PLoS One
Title: Postsynaptic target specific synaptic dysfunctions in the CA3 area of BACE1 knockout mice.
Volume: 9
Issue: 3
Pages: e92279
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Publication
18753368 | J:138795
First Author: Wang H
Year: 2008
Journal: J Neurosci
Title: BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus.
Volume: 28
Issue: 35
Pages: 8677-81
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Publication
28669600 | J:311971
First Author: Hou H
Year: 2017
Journal: Stem Cell Reports
Title: BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus.
Volume: 9
Issue: 1
Pages: 217-230
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Publication
28004339 | J:325881
First Author: Stertz L
Year: 2018
Journal: Mol Neurobiol
Title: BACE1-Deficient Mice Exhibit Alterations in Immune System Pathways.
Volume: 55
Issue: 1
Pages: 709-717
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Publication
25912880 | J:235920
First Author: Paredes RM
Year: 2015
Journal: Genes Brain Behav
Title: Physiological and behavioral effects of amphetamine in BACE1(-/-) mice.
Volume: 14
Issue: 5
Pages: 411-8
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Publication
30079376 | J:266883
 
First Author: Chatila ZK
Year: 2018
Journal: eNeuro
Title: BACE1 Regulates Proliferation and Neuronal Differentiation of Newborn Cells in the Adult Hippocampus in Mice.
Volume: 5
Issue: 4
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Publication
20731874 | J:163907
 
First Author: Hitt BD
Year: 2010
Journal: Mol Neurodegener
Title: BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization.
Volume: 5
Pages: 31
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Publication
20592204 | J:161845
First Author: Hu X
Year: 2010
Journal: J Neurosci
Title: BACE1 deficiency causes altered neuronal activity and neurodegeneration.
Volume: 30
Issue: 26
Pages: 8819-29
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Publication
36370042 | J:341140
First Author: Benoit MR
Year: 2023
Journal: Hum Mol Genet
Title: Postnatal neuronal Bace1 deletion impairs neuroblast and oligodendrocyte maturation.
Volume: 32
Issue: 7
Pages: 1193-1207
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Publication
16223892 | J:104122
First Author: Ferrer I
Year: 2005
Journal: Hum Mol Genet
Title: Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage.
Volume: 14
Issue: 23
Pages: 3565-77
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Publication
22685302 | J:269564
First Author: Purohit AA
Year: 2012
Journal: J Biol Chem
Title: Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
Volume: 287
Issue: 32
Pages: 27126-38
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Publication
7558004 | J:26193
First Author: Mock BA
Year: 1995
Journal: Genomics
Title: CHUK, a conserved helix-loop-helix ubiquitous kinase, maps to human chromosome 10 and mouse chromosome 19.
Volume: 27
Issue: 2
Pages: 348-51
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2575584 | J:22777
First Author: Reeves RH
Year: 1989
Journal: Genomics
Title: The mouse neurological mutant weaver maps within the region of chromosome 16 that is homologous to human chromosome 21.
Volume: 5
Issue: 3
Pages: 522-6
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10939329 | J:107720
First Author: Dulabon L
Year: 2000
Journal: Neuron
Title: Reelin binds alpha3beta1 integrin and inhibits neuronal migration.
Volume: 27
Issue: 1
Pages: 33-44
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Publication
19033669 | J:144730
First Author: Deane R
Year: 2008
Journal: J Clin Invest
Title: apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.
Volume: 118
Issue: 12
Pages: 4002-13
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Publication
22820466 | J:190064
First Author: Um JW
Year: 2012
Journal: Nat Neurosci
Title: Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons.
Volume: 15
Issue: 9
Pages: 1227-35
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Publication
12239221 | J:80658
First Author: Moore KJ
Year: 2002
Journal: J Biol Chem
Title: A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.
Volume: 277
Issue: 49
Pages: 47373-9
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Publication
29577585 | J:261918
First Author: Zhang Y
Year: 2018
Journal: Aging Cell
Title: nNOS-CAPON interaction mediates amyloid-β-induced neurotoxicity, especially in the early stages.
Volume: 17
Issue: 3
Pages: e12754
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Publication
15009636 | J:107993
First Author: Yang Y
Year: 2004
Journal: J Neurochem
Title: Presenilin-1 and intracellular calcium stores regulate neuronal glutamate uptake.
Volume: 88
Issue: 6
Pages: 1361-72
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Publication
26589795 | J:336700
First Author: Miyamoto T
Year: 2016
Journal: J Biol Chem
Title: Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity.
Volume: 291
Issue: 4
Pages: 1719-1734
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Publication
36747024 | J:333044
First Author: De Schepper S
Year: 2023
Journal: Nat Neurosci
Title: Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
Volume: 26
Issue: 3
Pages: 406-415
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Publication
16912050 | J:117188
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