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Search results 3401 to 3500 out of 7122 for App

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Type Details Score
Publication
35813949 | J:349609
 
First Author: Wu H
Year: 2022
Journal: Front Aging Neurosci
Title: The Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer's Pathogenesis via Specific Pathways.
Volume: 14
Pages: 912709
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Publication
33122702 | J:298930
First Author: Kantarci A
Year: 2020
Journal: Sci Rep
Title: Microglial response to experimental periodontitis in a murine model of Alzheimer's disease.
Volume: 10
Issue: 1
Pages: 18561
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Publication
38215888 | J:347904
 
First Author: Yang S
Year: 2024
Journal: Brain Behav Immun
Title: Multi-omics analysis reveals GAPDH posttranscriptional regulation of IFN-γ and PHGDH as a metabolic checkpoint of microglia polarization.
Volume: 117
Pages: 155-166
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Publication
36611911 | J:332601
 
First Author: Elangovan S
Year: 2022
Journal: Cells
Title: Fecal Microbiota Transplantation Reduces Pathology and Improves Cognition in a Mouse Model of Alzheimer's Disease.
Volume: 12
Issue: 1
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Publication
36620768 | J:332605
 
First Author: Smith DC
Year: 2022
Journal: Front Aging Neurosci
Title: Deletion of the Alzheimer's disease risk gene Abi3 locus results in obesity and systemic metabolic disruption in mice.
Volume: 14
Pages: 1035572
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Publication
33830999 | J:304862
First Author: Nackenoff AG
Year: 2021
Journal: PLoS Genet
Title: PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease.
Volume: 17
Issue: 4
Pages: e1009406
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Publication
39596222 | J:361431
 
First Author: Nairuz T
Year: 2024
Journal: Int J Mol Sci
Title: Differential Glial Response and Neurodegenerative Patterns in CA1, CA3, and DG Hippocampal Regions of 5XFAD Mice.
Volume: 25
Issue: 22
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Publication
26102198 | J:237887
First Author: Modi KK
Year: 2015
Journal: PLoS One
Title: Cinnamon and Its Metabolite Sodium Benzoate Attenuate the Activation of p21rac and Protect Memory and Learning in an Animal Model of Alzheimer's Disease.
Volume: 10
Issue: 6
Pages: e0130398
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Publication
35645763 | J:350958
 
First Author: Mackenzie-Gray Scott CA
Year: 2022
Journal: Front Synaptic Neurosci
Title: Resilient Hippocampal Gamma Rhythmogenesis and Parvalbumin-Expressing Interneuron Function Before and After Plaque Burden in 5xFAD Alzheimer's Disease Model.
Volume: 14
Pages: 857608
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Publication
35984475 | J:330857
 
First Author: Mishra R
Year: 2022
Journal: J Exp Med
Title: Augmenting neurogenesis rescues memory impairments in Alzheimer's disease by restoring the memory-storing neurons.
Volume: 219
Issue: 9
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Publication
31474828 | J:284351
 
First Author: Nam Y
Year: 2019
Journal: Front Mol Neurosci
Title: ALWPs Improve Cognitive Function and Regulate Aβ Plaque and Tau Hyperphosphorylation in a Mouse Model of Alzheimer's Disease.
Volume: 12
Pages: 192
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Publication
36939283 | J:350959
First Author: Kumro J
Year: 2023
Journal: Cereb Cortex
Title: Chronic basal forebrain activation improves spatial memory, boosts neurotrophin receptor expression, and lowers BACE1 and Aβ42 levels in the cerebral cortex in mice.
Volume: 33
Issue: 12
Pages: 7627-7641
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Publication
32958021 | J:327387
First Author: Shippy DC
Year: 2020
Journal: J Neuroinflammation
Title: β-Hydroxybutyrate inhibits inflammasome activation to attenuate Alzheimer's disease pathology.
Volume: 17
Issue: 1
Pages: 280
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Publication
39542183 | J:361433
First Author: Lee Y
Year: 2024
Journal: Biochem Pharmacol
Title: 3,4,5-trimethoxycinnamic acid methyl ester isolated from Polygala tenuifolia enhances hippocampal LTP through PKA and calcium-permeable AMPA receptor.
Volume: 230
Issue: Pt 3
Pages: 116622
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Publication
39026249 | J:359157
First Author: Wang Z
Year: 2024
Journal: J Neuroinflammation
Title: Herpes simplex virus 1 accelerates the progression of Alzheimer's disease by modulating microglial phagocytosis and activating NLRP3 pathway.
Volume: 21
Issue: 1
Pages: 176
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Publication
37774676 | J:341730
First Author: Lu Z
Year: 2023
Journal: Cell
Title: Tracking cell-type-specific temporal dynamics in human and mouse brains.
Volume: 186
Issue: 20
Pages: 4345-4364.e24
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Publication
36462718 | J:332229
 
First Author: Zhang H
Year: 2023
Journal: Neurobiol Dis
Title: Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease.
Volume: 176
Pages: 105939
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Publication
38496847 | J:359158
First Author: Gao S
Year: 2024
Journal: Heliyon
Title: Dynamics of N6-methyladenosine modification during Alzheimer's disease development.
Volume: 10
Issue: 6
Pages: e26911
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Publication
37164302 | J:341772
 
First Author: Yao J
Year: 2023
Journal: Neuroscience
Title: A Gain-of-function Mutation in the Gating Domain of ITPR1 Impairs Motor Movement and Increases Thermal and Mechanical Sensitivity.
Volume: 522
Pages: 11-22
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Publication
32619873 | J:298312
 
First Author: Wang S
Year: 2020
Journal: Neurobiol Aging
Title: Early-stage dysfunction of hippocampal theta and gamma oscillations and its modulation of neural network in a transgenic 5xFAD mouse model.
Volume: 94
Pages: 121-129
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Publication
34856990 | J:327391
First Author: Rui W
Year: 2021
Journal: J Neuroinflammation
Title: Systemic inflammasome activation and pyroptosis associate with the progression of amnestic mild cognitive impairment and Alzheimer's disease.
Volume: 18
Issue: 1
Pages: 280
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Publication
33422057 | J:327388
First Author: Fassler M
Year: 2021
Journal: J Neuroinflammation
Title: Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer's disease models.
Volume: 18
Issue: 1
Pages: 19
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Publication
35717259 | J:347605
First Author: Zhao P
Year: 2022
Journal: Mol Neurodegener
Title: LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions.
Volume: 17
Issue: 1
Pages: 44
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Publication
33758244 | J:304922
First Author: Rosales Jubal E
Year: 2021
Journal: Sci Rep
Title: Acitretin reverses early functional network degradation in a mouse model of familial Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 6649
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Publication
39392753 | J:358119
First Author: Osborne OM
Year: 2024
Journal: Cell Rep
Title: Post-stroke hippocampal neurogenesis is impaired by microvascular dysfunction and PI3K signaling in cerebral amyloid angiopathy.
Volume: 43
Issue: 10
Pages: 114848
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Publication
32599514 | J:298313
 
First Author: Weible AP
Year: 2020
Journal: Neurobiol Aging
Title: 5XFAD mice show early-onset gap encoding deficits in the auditory cortex.
Volume: 94
Pages: 101-110
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Publication
31929163 | J:355624
First Author: Ano Y
Year: 2020
Journal: J Alzheimers Dis
Title: β-Lactolin, a Whey-Derived Lacto-Tetrapeptide, Prevents Alzheimer's Disease Pathologies and Cognitive Decline.
Volume: 73
Issue: 4
Pages: 1331-1342
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Publication
22503002 | J:191369
First Author: Kim C
Year: 2013
Journal: Neurobiol Aging
Title: O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment.
Volume: 34
Issue: 1
Pages: 275-85
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Publication
32791516 | J:294346
First Author: Jeong J
Year: 2020
Journal: PLoS One
Title: JBPOS0101 regulates amyloid beta, tau, and glial cells in an Alzheimer's disease model.
Volume: 15
Issue: 8
Pages: e0237153
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Publication
36653878 | J:334413
First Author: Vasciaveo V
Year: 2023
Journal: Acta Neuropathol Commun
Title: Sleep fragmentation affects glymphatic system through the different expression of AQP4 in wild type and 5xFAD mouse models.
Volume: 11
Issue: 1
Pages: 16
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Publication
36494892 | J:334412
First Author: Liang X
Year: 2023
Journal: Aging Cell
Title: Exosomal miR-532-5p induced by long-term exercise rescues blood-brain barrier function in 5XFAD mice via downregulation of EPHA4.
Volume: 22
Issue: 1
Pages: e13748
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Publication
25008761 | J:215635
 
First Author: Fragkouli A
Year: 2014
Journal: Neurobiol Dis
Title: Neuroprotective role of MMP-9 overexpression in the brain of Alzheimer's 5xFAD mice.
Volume: 70
Pages: 179-89
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Publication
35046767 | J:349770
 
First Author: Viola KL
Year: 2021
Journal: Front Neurosci
Title: The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease.
Volume: 15
Pages: 768646
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Publication
35496999 | J:324605
First Author: Dong Q
Year: 2022
Journal: iScience
Title: Familial natural short sleep mutations reduce Alzheimer pathology in mice.
Volume: 25
Issue: 4
Pages: 103964
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Publication
36254682 | J:330956
 
First Author: Monzón-Sandoval J
Year: 2022
Journal: Dis Model Mech
Title: Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models.
Volume: 15
Issue: 10
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Publication
36219197 | J:350035
 
First Author: Jain N
Year: 2023
Journal: J Exp Med
Title: Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading.
Volume: 220
Issue: 1
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Publication
34745215 | J:319460
 
First Author: Lim KH
Year: 2021
Journal: Front Genet
Title: Identifying New COVID-19 Receptor Neuropilin-1 in Severe Alzheimer's Disease Patients Group Brain Using Genome-Wide Association Study Approach.
Volume: 12
Pages: 741175
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Publication
31618637 | J:284703
First Author: Carrillo-Jimenez A
Year: 2019
Journal: Cell Rep
Title: TET2 Regulates the Neuroinflammatory Response in Microglia.
Volume: 29
Issue: 3
Pages: 697-713.e8
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Publication
37407605 | J:337946
First Author: Lee D
Year: 2023
Journal: Sci Rep
Title: Carprofen alleviates Alzheimer-like phenotypes of 5XFAD transgenic mice by targeting the pathological hallmarks induced by amyloid-β aggregation.
Volume: 13
Issue: 1
Pages: 10889
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Publication
30224067 | J:272467
First Author: Kim DH
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Effect of growth differentiation factor-15 secreted by human umbilical cord blood-derived mesenchymal stem cells on amyloid beta levels in in vitro and in vivo models of Alzheimer's disease.
Volume: 504
Issue: 4
Pages: 933-940
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Publication
34312845 | J:319467
First Author: Choi C
Year: 2021
Journal: J Pathol
Title: DSCR1 upregulation enhances dural meningeal lymphatic drainage to attenuate amyloid pathology of Alzheimer's disease.
Volume: 255
Issue: 3
Pages: 296-310
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Publication
33139698 | J:297772
First Author: Trzeciakiewicz H
Year: 2020
Journal: Nat Commun
Title: An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline.
Volume: 11
Issue: 1
Pages: 5522
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Publication
27265785 | J:249653
First Author: Neuner SM
Year: 2017
Journal: Behav Brain Res
Title: Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models.
Volume: 322
Issue: Pt B
Pages: 288-298
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Publication
39316084 | J:359168
 
First Author: Cao Q
Year: 2024
Journal: J Exp Med
Title: Transport of β-amyloid from brain to eye causes retinal degeneration in Alzheimer's disease.
Volume: 221
Issue: 11
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Publication
33397809 | J:300753
 
First Author: Kim SH
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Prediction of Alzheimer's disease-specific phospholipase c gamma-1 SNV by deep learning-based approach for high-throughput screening.
Volume: 118
Issue: 3
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Publication
37620442 | J:350080
First Author: Jorfi M
Year: 2023
Journal: Nat Neurosci
Title: Infiltrating CD8(+) T cells exacerbate Alzheimer's disease pathology in a 3D human neuroimmune axis model.
Volume: 26
Issue: 9
Pages: 1489-1504
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Publication
39490772 | J:360709
 
First Author: He K
Year: 2024
Journal: Free Radic Biol Med
Title: Sevoflurane exposure accelerates the onset of cognitive impairment via promoting p-Drp1(S616)-mediated mitochondrial fission in a mouse model of Alzheimer's disease.
Volume: 225
Pages: 699-710
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Publication
34776451 | J:359233
First Author: Chum PP
Year: 2022
Journal: J Alzheimers Dis
Title: Cerebrovascular microRNA Expression Profile During Early Development of Alzheimer's Disease in a Mouse Model.
Volume: 85
Issue: 1
Pages: 91-113
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Publication
38884283 | J:360714
First Author: Yao Y
Year: 2024
Journal: Alzheimers Dement
Title: A small-molecule microtubule-stabilizing agent safely reduces Aβ plaque and tau pathology in transgenic mouse models of Alzheimer's disease.
Volume: 20
Issue: 7
Pages: 4540-4558
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Publication
39394148 | J:359171
First Author: Xiong X
Year: 2024
Journal: Cell Death Dis
Title: NAD(+)-boosting agent nicotinamide mononucleotide potently improves mitochondria stress response in Alzheimer's disease via ATF4-dependent mitochondrial UPR.
Volume: 15
Issue: 10
Pages: 744
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Publication
37847596 | J:359232
First Author: Kandi S
Year: 2023
Journal: J Proteome Res
Title: Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer's Disease.
Volume: 22
Issue: 11
Pages: 3475-3488
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Publication
39434878 | J:359173
 
First Author: Lee HJ
Year: 2024
Journal: Front Immunol
Title: Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD.
Volume: 15
Pages: 1421455
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Publication
34170616 | J:359229
First Author: Su SH
Year: 2021
Journal: Small
Title: Ultrasensitive Multiparameter Phenotyping of Rare Cells Using an Integrated Digital-Molecular-Counting Microfluidic Well Plate.
Volume: 17
Issue: 31
Pages: e2101743
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Publication
39431020 | J:359174
First Author: Shojaei M
Year: 2024
Journal: Theranostics
Title: PET imaging of microglia in Alzheimer's disease using copper-64 labeled TREM2 antibodies.
Volume: 14
Issue: 16
Pages: 6319-6336
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Publication
31932797 | J:284722
First Author: Zhou Y
Year: 2020
Journal: Nat Med
Title: Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Volume: 26
Issue: 1
Pages: 131-142
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Publication
39205389 | J:360712
First Author: Fonseca-Gomes J
Year: 2024
Journal: Mol Ther
Title: A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease.
Volume: 32
Issue: 10
Pages: 3372-3401
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Publication
25637807 | J:221806
 
First Author: Sethi M
Year: 2015
Journal: Neuroscience
Title: Increased fragmentation of sleep-wake cycles in the 5XFAD mouse model of Alzheimer's disease.
Volume: 290
Pages: 80-9
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Publication
23402900 | J:211692
First Author: Rojas S
Year: 2013
Journal: Neurobiol Aging
Title: In vivo evaluation of amyloid deposition and brain glucose metabolism of 5XFAD mice using positron emission tomography.
Volume: 34
Issue: 7
Pages: 1790-8
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Publication
39268577 | J:355470
First Author: Campoy-Campos G
Year: 2024
Journal: Nucleic Acids Res
Title: RTP801 interacts with the tRNA ligase complex and dysregulates its RNA ligase activity in Alzheimer's disease.
Volume: 52
Issue: 18
Pages: 11158-11176
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Publication
37984409 | J:358193
First Author: Na D
Year: 2023
Journal: Mol Syst Biol
Title: A multi-layered network model identifies Akt1 as a common modulator of neurodegeneration.
Volume: 19
Issue: 12
Pages: e11801
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Publication
33737550 | J:305021
First Author: Lim JKH
Year: 2021
Journal: Sci Rep
Title: Retinal hyperspectral imaging in the 5xFAD mouse model of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 6387
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Publication
37333676 | J:351093
 
First Author: Smith S
Year: 2023
Journal: Aging Brain
Title: The 5XFAD mouse model of Alzheimer's disease displays age-dependent deficits in habituation to a novel environment.
Volume: 3
Pages: 100078
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Publication
39522980 | J:360722
First Author: Matsuoka Y
Year: 2024
Journal: Biol Pharm Bull
Title: Expression Profiles of Brain-Derived Neurotrophic Factor Splice Variants in the Hippocampus of Alzheimer's Disease Model Mouse.
Volume: 47
Issue: 11
Pages: 1858-1867
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Publication
39557828 | J:360720
First Author: Wang X
Year: 2024
Journal: Cell Discov
Title: Sodium oligomannate disrupts the adherence of Rib(high) bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice.
Volume: 10
Issue: 1
Pages: 115
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Publication
29321225 | J:259750
First Author: Song WM
Year: 2018
Journal: J Exp Med
Title: Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
Volume: 215
Issue: 3
Pages: 745-760
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Publication
39044270 | J:360704
First Author: Chen M
Year: 2024
Journal: Transl Neurodegener
Title: Dorsal raphe nucleus-hippocampus serotonergic circuit underlies the depressive and cognitive impairments in 5×FAD male mice.
Volume: 13
Issue: 1
Pages: 34
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Publication
38032015 | J:350118
First Author: Chumin EJ
Year: 2024
Journal: Alzheimers Dement
Title: Brain metabolic network covariance and aging in a mouse model of Alzheimer's disease.
Volume: 20
Issue: 3
Pages: 1538-1549
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Publication
38965625 | J:360733
First Author: Lee S
Year: 2024
Journal: Chin Med
Title: Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse.
Volume: 19
Issue: 1
Pages: 95
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Publication
37961834 | J:350115
First Author: Odfalk KF
Year: 2024
Journal: Hippocampus
Title: Hippocampal TMEM55B overexpression in the 5XFAD mouse model of Alzheimer's disease.
Volume: 34
Issue: 1
Pages: 29-35
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Genotype
Genotype
Symbol: Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
Background: B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
Background: B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(Thy1-APP)28Lpr/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Publication
17314294 | J:118376
First Author: Rockenstein E
Year: 2007
Journal: J Neurosci
Title: Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation.
Volume: 27
Issue: 8
Pages: 1981-91
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Publication
37547981 | J:343749
First Author: He T
Year: 2023
Journal: J Neurochem
Title: BACE2 deficiency impairs expression and function of endothelial nitric oxide synthase in brain endothelial cells.
Volume: 166
Issue: 6
Pages: 928-942
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Publication
11744223 | J:108752
First Author: Wirths O
Year: 2001
Journal: Neurosci Lett
Title: Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice.
Volume: 316
Issue: 3
Pages: 145-8
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Publication
19643098 | J:157207
 
First Author: Filali M
Year: 2009
Journal: Brain Res
Title: Age-related cognitive decline and nesting behavior in an APPswe/PS1 bigenic model of Alzheimer's disease.
Volume: 1292
Pages: 93-9
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Allele
Tg(Eno2-APP*751)10Cord | MGI:3784388
Name: transgene insertion 10, Barbara Cordell
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(ACTB-APP)1Colm | MGI:4438113
Name: transgene insertion 1, Colin L Masters
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Thy1-APPSwDutLon)101Lpr | MGI:5003456
Name: transgene insertion 101, Laurent Pradier
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-APPSweOsa)#Luk | MGI:6378818
Name: transgene insertion, Luka Kulic
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:7382406 | C57BL/6JGpt-Tg(Thy-APPSweInd,-PSEN1*M146V*L286V)5Gpt/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7577214 | C57BL/6JGpt-Tg(Thy1-APP*Swe,-PSEN1*)24Gpt/Gpt
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:7577201 | C57BL/6JGpt-Tg(Thy1-APPSwe,-MAPT*P301L,-PSEN1*M146V)17Gpt/Gpt
Attribute String: coisogenic, mutant strain, transgenic
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Allele
App<em7Msasn> | MGI:7703876
Name: amyloid beta precursor protein; endonuclease-mediated mutation 7, Michael Sasner
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Allele
App<em8Msasn> | MGI:7703878
Name: amyloid beta precursor protein; endonuclease-mediated mutation 7, Michael Sasner
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Genotype
Genotype
Symbol: Tg(APPSWE)2576Kha/? Tg(Prnp-MAPT*P301L)JNPL3Hlmc/?
Background: involves: C57BL/6 * DBA/2 * SJL * SW
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ldlr/Ldlr Tg(APPSWE)2576Kha/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APPSweArc)BLngn/?
Background: B6J.Cg-Tg(Thy1-APPSweArc)BLngn
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APP*Swe*Ind)fAccu/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Publication
16733088 | J:111313
First Author: Ethell DW
Year: 2006
Journal: Neurobiol Dis
Title: Abeta-specific T-cells reverse cognitive decline and synaptic loss in Alzheimer's mice.
Volume: 23
Issue: 2
Pages: 351-61
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Publication
9168112 | J:80639
First Author: Nalbantoglu J
Year: 1997
Journal: Nature
Title: Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein.
Volume: 387
Issue: 6632
Pages: 500-5
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Publication
16307858 | J:128243
First Author: Wirths O
Year: 2006
Journal: Exp Gerontol
Title: Decreased plasma cholesterol levels during aging in transgenic mouse models of Alzheimer's disease.
Volume: 41
Issue: 2
Pages: 220-4
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Publication
17192425 | J:144657
First Author: Saganich MJ
Year: 2006
Journal: J Neurosci
Title: Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP.
Volume: 26
Issue: 52
Pages: 13428-36
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Publication
27681803 | J:254081
 
First Author: Do Carmo S
Year: 2016
Journal: Sci Rep
Title: Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model.
Volume: 6
Pages: 34051
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Allele
Tg(PDGFB-APP)5Lms | MGI:3057135
Name: transgene insertion 5, Lennart Mucke
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Ide<Gt(OST132429)Lex> | MGI:3530576
Name: insulin degrading enzyme; gene trap OST132429, Lexicon Genetics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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Transgene
MGI:3603940 | Tg(PDGFB-APPSweIndArc)48Lms
Type: transgene
Organism: mouse, laboratory
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Allele
Flot1<tm1.1Arte> | MGI:4868388
Name: flotillin 1; targeted mutation 1.1, TaconicArtemis
Allele Type: Targeted
Attribute String: Null/knockout
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Transgene
MGI:5052115 | Tg(Eno2-PSEN2)2348Ykk
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5052117 | Tg(Eno2-PSEN2*)1480Ykk
Type: transgene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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