Type |
Details |
Score |
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents a domain found in DNA methyltransferase 1-associated protein 1 (DMAP1). DNA methylation can contribute to transcriptional silencing through several transcriptionally repressive complexes, which include methyl-CpG binding domain proteins (MBDs) and histone deacetylases (HDACs). The chief enzyme that maintains mammalian DNA methylation, DNMT1, can also establish a repressive transcription complex. The non-catalytic N terminus of DNMT1 binds to HDAC2 and DMAP1, and can mediate transcriptional repression. DMAP1 has intrinsic transcription repressive activity, and binds to the transcriptional co-repressor TSG101. DMAP1 is targeted to replication foci through interaction with the far N terminus of DNMT1 throughout S phase, whereas HDAC2 joins DNMT1 and DMAP1 only during late S phase, providing a platform for how histones may become deacetylated in heterochromatin following replication []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Corona M |
Year: |
1991 |
Journal: |
Anat Histol Embryol |
Title: |
[The sensitive nerve endings of the clitoris of the sow (Sus scrofa domesticus)]. |
Volume: |
20 |
Issue: |
4 |
Pages: |
369-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Syeda F |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1. |
Volume: |
286 |
Issue: |
17 |
Pages: |
15344-51 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This domain is part of a cytosine specific DNA methyltransferase enzyme (DNMT). It functions non-catalytically to target the protein towards replication foci. This allows the DNMT1 protein to methylate the correct residues. This domain targets DMAP1 and HDAC2 to the replication foci during the S phase of mitosis. They are thought to have some importance in conversion of critical histone lysine moieties [].A structure exists for the human cytosine specific DNA methyltransferase replication foci domain []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents DNA (cytosine-5)-methyltransferase 1 (Dnmt1; ), which methylates CpG residues, with a preference for hemimethylated DNA. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Dnmt1 mediates transcriptional repression (silencing) by establishing a repressive transcription complex where the N terminus of Dnmt1 binds to HDAC2 (histone deacetylase-2) as well as to DMAP1 (Dnmt1-associated protein) []. LSH, which is related to the SNF2 chromatin-remodelling ATPases, is also required for efficient DNA methylation []. |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Kolos JM |
Year: |
2018 |
Journal: |
Front Pharmacol |
Title: |
FKBP Ligands-Where We Are and Where to Go? |
Volume: |
9 |
|
Pages: |
1425 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang WM |
Year: |
2001 |
Journal: |
EMBO J |
Title: |
The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1. |
Volume: |
20 |
Issue: |
17 |
Pages: |
4814-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu W |
Year: |
2017 |
Journal: |
Theranostics |
Title: |
FKBP3 Promotes Proliferation of Non-Small Cell Lung Cancer Cells through Regulating Sp1/HDAC2/p27. |
Volume: |
7 |
Issue: |
12 |
Pages: |
3078-3089 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dilworth D |
Year: |
2017 |
Journal: |
Nucleic Acids Res |
Title: |
The basic tilted helix bundle domain of the prolyl isomerase FKBP25 is a novel double-stranded RNA binding module. |
Volume: |
45 |
Issue: |
20 |
Pages: |
11989-12004 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
FKBP3, also known as FKBP25, contains the N-terminal basic tilted helix bundle (BTHB) domain and the C-terminal PPIase domain. It is a nuclear prolyl isomerase that interacts directlywith nucleic acids []. It interacts with the histone deacetylases HDAC1 and HDAC2 as well as with their transcriptional regulator Yin Yang 1 (YY1) []. It is also a microtubule-associated protein that shuttles between nucleus and cytoplasm and stabilizes the microtubule network by direct binding of the C-terminal PPIase domain []. It plays a role in the proliferation of non-small cell type lung cancer cells (NSCLC) by modulating Sp1/HDAC2/p27 []. |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE35432 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
468
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
162
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
76
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
88
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang SH |
Year: |
2005 |
Journal: |
EMBO J |
Title: |
PIASx acts as an Elk-1 coactivator by facilitating derepression. |
Volume: |
24 |
Issue: |
12 |
Pages: |
2161-71 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
SUMO proteins are ubiquitin like proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMO is first activated in an ATP-dependent reaction by formation of a thioester bond with an E1 (SUMO-activating) enzyme and then transferred to the SUMO conjugating (E2) enzyme Ubc9. Ubc9 catalyses the formation of an isopeptide bond between the C-terminal of SUMO and the amino group of lysine in the target protein. Sumoylated proteins can be targeted for different cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability []. PIAS2 is an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilising the interaction between Ubc9 and the substrate, and is a SUMO-tethering factor. It plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing may vary depending upon the biological context and PIAS2 isoform studied. However, it seems to be mostly involved in gene silencing. It binds to sumoylated ELK1 and enhances its transcriptional activity by preventing recruitment of HDAC2 by ELK1, thus reversing SUMO-mediated repression of ELK1 transactivation activity [, ]. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang T |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes. |
Volume: |
9 |
Issue: |
1 |
Pages: |
3798 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang C |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers. |
Volume: |
8 |
Issue: |
5 |
Pages: |
1497-508 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsui K |
Year: |
2013 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter. |
Volume: |
440 |
Issue: |
1 |
Pages: |
184-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka S |
Year: |
2020 |
Journal: |
Nat Immunol |
Title: |
Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity. |
Volume: |
21 |
Issue: |
8 |
Pages: |
950-961 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kennedy AJ |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function. |
Volume: |
16 |
Issue: |
10 |
Pages: |
2666-2685 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fukumoto T |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer. |
Volume: |
22 |
Issue: |
13 |
Pages: |
3393-3400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jin X |
Year: |
2017 |
Journal: |
Front Cell Neurosci |
Title: |
Neuronal Nitric Oxide Synthase in Neural Stem Cells Induces Neuronal Fate Commitment via the Inhibition of Histone Deacetylase 2. |
Volume: |
11 |
|
Pages: |
66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosenberg LH |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State. |
Volume: |
25 |
Issue: |
10 |
Pages: |
2755-2765.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hosokawa H |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells. |
Volume: |
7 |
|
Pages: |
11289 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rei D |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway. |
Volume: |
112 |
Issue: |
23 |
Pages: |
7291-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baumann C |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
4486 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu R |
Year: |
2009 |
Journal: |
Cancer Res |
Title: |
FOXP3 up-regulates p21 expression by site-specific inhibition of histone deacetylase 2/histone deacetylase 4 association to the locus. |
Volume: |
69 |
Issue: |
6 |
Pages: |
2252-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao Z |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Epigenetic alterations regulate estradiol-induced enhancement of memory consolidation. |
Volume: |
107 |
Issue: |
12 |
Pages: |
5605-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qin L |
Year: |
2018 |
Journal: |
Nat Neurosci |
Title: |
Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. |
Volume: |
21 |
Issue: |
4 |
Pages: |
564-575 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
1999 |
Journal: |
Genes Dev |
Title: |
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. |
Volume: |
13 |
Issue: |
15 |
Pages: |
1924-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cong L |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
SUMOylation and SUMO-interacting motif (SIM) of metastasis tumor antigen 1 (MTA1) synergistically regulate its transcriptional repressor function. |
Volume: |
286 |
Issue: |
51 |
Pages: |
43793-808 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marinho D |
Year: |
2023 |
Journal: |
Aging Cell |
Title: |
Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease. |
Volume: |
22 |
Issue: |
8 |
Pages: |
e13895 |
|
•
•
•
•
•
|
Publication |
First Author: |
Forzati F |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
CBX7 is a tumor suppressor in mice and humans. |
Volume: |
122 |
Issue: |
2 |
Pages: |
612-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hendrickx A |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease. |
Volume: |
9 |
Issue: |
6 |
Pages: |
e99467 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vengoji R |
Year: |
2021 |
Journal: |
J Exp Clin Cancer Res |
Title: |
Differential gene expression-based connectivity mapping identified novel drug candidate and improved Temozolomide efficacy for Glioblastoma. |
Volume: |
40 |
Issue: |
1 |
Pages: |
335 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shapson-Coe A |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Aicardi-Goutières Syndrome associated mutations of RNase H2B impair its interaction with ZMYM3 and the CoREST histone-modifying complex. |
Volume: |
14 |
Issue: |
3 |
Pages: |
e0213553 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sada N |
Year: |
2020 |
Journal: |
Cell Death Dis |
Title: |
Inhibition of HDAC increases BDNF expression and promotes neuronal rewiring and functional recovery after brain injury. |
Volume: |
11 |
Issue: |
8 |
Pages: |
655 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2021 |
Journal: |
Sci Transl Med |
Title: |
Targeting epigenetically maladapted vascular niche alleviates liver fibrosis in nonalcoholic steatohepatitis. |
Volume: |
13 |
Issue: |
614 |
Pages: |
eabd1206 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen-Tran DH |
Year: |
2014 |
Journal: |
Dis Model Mech |
Title: |
Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy. |
Volume: |
7 |
Issue: |
1 |
Pages: |
41-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hsiao YH |
Year: |
2017 |
Journal: |
Neurobiol Learn Mem |
Title: |
Co-housing reverses memory decline by epigenetic regulation of brain-derived neurotrophic factor expression in an animal model of Alzheimer's disease. |
Volume: |
141 |
|
Pages: |
1-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Santoro F |
Year: |
2013 |
Journal: |
Blood |
Title: |
A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance. |
Volume: |
121 |
Issue: |
17 |
Pages: |
3459-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar V |
Year: |
2019 |
Journal: |
Front Mol Neurosci |
Title: |
Simvastatin Restores HDAC1/2 Activity and Improves Behavioral Deficits in Angelman Syndrome Model Mouse. |
Volume: |
12 |
|
Pages: |
289 |
|
•
•
•
•
•
|
Publication |
First Author: |
Backlund MG |
Year: |
2008 |
Journal: |
Cancer Res |
Title: |
Repression of 15-hydroxyprostaglandin dehydrogenase involves histone deacetylase 2 and snail in colorectal cancer. |
Volume: |
68 |
Issue: |
22 |
Pages: |
9331-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar P |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Histone deacetylase inhibitors modulate the transcriptional regulation of guanylyl cyclase/natriuretic peptide receptor-a gene: interactive roles of modified histones, histone acetyltransferase, p300, AND Sp1. |
Volume: |
289 |
Issue: |
10 |
Pages: |
6991-7002 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eom GH |
Year: |
2014 |
Journal: |
Circ Res |
Title: |
Regulation of acetylation of histone deacetylase 2 by p300/CBP-associated factor/histone deacetylase 5 in the development of cardiac hypertrophy. |
Volume: |
114 |
Issue: |
7 |
Pages: |
1133-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng B |
Year: |
2014 |
Journal: |
Diabetes |
Title: |
Mitogen-activated protein kinase phosphatase 3 (MKP-3)-deficient mice are resistant to diet-induced obesity. |
Volume: |
63 |
Issue: |
9 |
Pages: |
2924-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmidt D |
Year: |
2008 |
Journal: |
Exp Cell Res |
Title: |
Blimp-1Deltaexon7: a naturally occurring Blimp-1 deletion mutant with auto-regulatory potential. |
Volume: |
314 |
Issue: |
20 |
Pages: |
3614-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khier H |
Year: |
1999 |
Journal: |
Biochim Biophys Acta |
Title: |
Molecular cloning and characterization of the mouse histone deacetylase 1 gene: integration of a retrovirus in 129SV mice. |
Volume: |
1489 |
Issue: |
2-3 |
Pages: |
365-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Grozinger CM |
Year: |
1999 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Three proteins define a class of human histone deacetylases related to yeast Hda1p. |
Volume: |
96 |
Issue: |
9 |
Pages: |
4868-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zupkovitz G |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
Negative and positive regulation of gene expression by mouse histone deacetylase 1. |
Volume: |
26 |
Issue: |
21 |
Pages: |
7913-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Z |
Year: |
2006 |
Journal: |
Biochem J |
Title: |
Recruitment of the SWI/SNF protein Brg1 by a multiprotein complex effects transcriptional repression in murine erythroid progenitors. |
Volume: |
399 |
Issue: |
2 |
Pages: |
297-304 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2005 |
Journal: |
Nucleic Acids Res |
Title: |
The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription. |
Volume: |
33 |
Issue: |
18 |
Pages: |
6024-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2011 |
Journal: |
Genes Dev |
Title: |
Mule determines the apoptotic response to HDAC inhibitors by targeted ubiquitination and destruction of HDAC2. |
Volume: |
25 |
Issue: |
24 |
Pages: |
2610-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ihlefeld K |
Year: |
2012 |
Journal: |
Biochem J |
Title: |
Evidence for a link between histone deacetylation and Ca²+ homoeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts. |
Volume: |
447 |
Issue: |
3 |
Pages: |
457-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hwang-Verslues WW |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy. |
Volume: |
110 |
Issue: |
30 |
Pages: |
12331-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Desai MA |
Year: |
2015 |
Journal: |
Nucleic Acids Res |
Title: |
An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex. |
Volume: |
43 |
Issue: |
6 |
Pages: |
3100-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sleiman SF |
Year: |
2016 |
Journal: |
Elife |
Title: |
Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Vilhais-Neto GC |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry. |
Volume: |
8 |
Issue: |
1 |
Pages: |
728 |
|
•
•
•
•
•
|
Publication |
First Author: |
Srivas S |
Year: |
2018 |
Journal: |
J Neurochem |
Title: |
Transcriptional co-repressor SIN3A silencing rescues decline in memory consolidation during scopolamine-induced amnesia. |
Volume: |
145 |
Issue: |
3 |
Pages: |
204-216 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nieto-Estevez V |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
HDAC1 Regulates Neuronal Differentiation. |
Volume: |
14 |
|
Pages: |
815808 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng X |
Year: |
2023 |
Journal: |
Cancer Res |
Title: |
The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization. |
Volume: |
83 |
Issue: |
14 |
Pages: |
2345-2357 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ravanelli F |
Year: |
2023 |
Journal: |
Int J Mol Sci |
Title: |
Differential Epigenetic Changes in the Dorsal Hippocampus of Male and Female SAMP8 Mice: A Preliminary Study. |
Volume: |
24 |
Issue: |
17 |
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
224
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
224
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
149
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
188
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Shinbo Y |
Year: |
2006 |
Journal: |
Cell Death Differ |
Title: |
Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities. |
Volume: |
13 |
Issue: |
1 |
Pages: |
96-108 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Singh VP |
Year: |
2019 |
Journal: |
Reproduction |
Title: |
Oocyte-specific deletion of Hdac8 in mice reveals stage-specific effects on fertility. |
Volume: |
157 |
Issue: |
3 |
Pages: |
305-316 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang M |
Year: |
2020 |
Journal: |
J Mol Cell Cardiol |
Title: |
CaMKII exacerbates heart failure progression by activating class I HDACs. |
Volume: |
149 |
|
Pages: |
73-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bai S |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2. |
Volume: |
25 |
Issue: |
2 |
Pages: |
751-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robertson ED |
Year: |
2012 |
Journal: |
J Cell Sci |
Title: |
ARNT controls the expression of epidermal differentiation genes through HDAC- and EGFR-dependent pathways. |
Volume: |
125 |
Issue: |
Pt 14 |
Pages: |
3320-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panikker P |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Restoring Tip60 HAT/HDAC2 Balance in the Neurodegenerative Brain Relieves Epigenetic Transcriptional Repression and Reinstates Cognition. |
Volume: |
38 |
Issue: |
19 |
Pages: |
4569-4583 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
742
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1501
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1620
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1619
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1627
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
252
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Su HL |
Year: |
2002 |
Journal: |
Gene |
Title: |
Molecular features of human ubiquitin-like SUMO genes and their encoded proteins. |
Volume: |
296 |
Issue: |
1-2 |
Pages: |
65-73 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
621
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
565
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
614
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|