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Search results 101 to 121 out of 121 for Smg9

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0.023s
Type Details Score
Allele  
Name: SMG9 nonsense mediated mRNA decay factor; gene trap IST14109C6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Strain
Attribute String: coisogenic, targeted mutation
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Allele  
Name: SMG9 nonsense mediated mRNA decay factor; gene trap IST13177D9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: SMG9 nonsense mediated mRNA decay factor; gene trap IST13206E11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: SMG9 nonsense mediated mRNA decay factor; gene trap IST14250B10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: SMG9 nonsense mediated mRNA decay factor; gene trap IST14862H4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: SMG9 nonsense mediated mRNA decay factor; gene trap IST14906B1, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: SMG9 nonsense mediated mRNA decay factor; gene trap IST12381H7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Genotype
Symbol: Smg9/Smg9
Background: C57BL/6N-Smg9/Wtsi
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Smg9/Smg9
Background: C57BL/6-Smg9
Zygosity: hm
Has Mutant Allele: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Genotype
Symbol: Smg9/Smg9<+>
Background: C57BL/6NJ-Smg9/J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Smg9/Smg9<+>
Background: C57BL/6-Smg9
Zygosity: ht
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 991  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: true
Protein Domain
Type: Family
Description: SMG8 is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. In humans, it is a component of the SMG1C complex composed of SMG1, SMG8 and SMG9 []. SMG-8 can recruit SMG-1 to the mRNA surveillance complex and can regulate the kinase activity of SMG-1 [].
Protein Domain
Type: Family
Description: SMG8 and SMG9 are two subunits of the Smg-1 complex. They suppress Smg-1 kinase activity in the isolated Smg-1 complex, and are involved in nonsense-mediated mRNA decay (NMD) in both mammals and nematodes []. NMD is a surveillance mechanism that detects and degrades mRNAs containing premature translation termination codons.
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112