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Search results 101 to 200 out of 2795 for Egfr

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Type Details Score
Publication
18487371 | J:141686
First Author: Jin C
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development.
Volume: 49
Issue: 10
Pages: 4245-53
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Publication
32150794 | J:297736
First Author: Kim MJ
Year: 2020
Journal: Mol Cells
Title: Reduced EGFR Level in eIF2α PhosphorylationDeficient Hepatocytes Is Responsible for Susceptibility to Oxidative Stress.
Volume: 43
Issue: 3
Pages: 264-275
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Publication
27881077 | J:316735
First Author: Liu F
Year: 2016
Journal: BMC Genet
Title: Sex difference in EGFR pathways in mouse kidney-potential impact on the immune system.
Volume: 17
Issue: 1
Pages: 146
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Publication
29093447 | J:256217
First Author: Rübsam M
Year: 2017
Journal: Nat Commun
Title: E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning.
Volume: 8
Issue: 1
Pages: 1250
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Publication
27586651 | J:240432
First Author: Scheving LA
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte ERBB3 and EGFR are required for maximal CCl4-induced liver fibrosis.
Volume: 311
Issue: 5
Pages: G807-G816
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Publication
22565824 | J:189051
First Author: Franzke CW
Year: 2012
Journal: J Exp Med
Title: Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.
Volume: 209
Issue: 6
Pages: 1105-19
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Publication
29992578 | J:301655
First Author: Song H
Year: 2019
Journal: Int J Cancer
Title: GPRC5A deficiency leads to dysregulated MDM2 via activated EGFR signaling for lung tumor development.
Volume: 144
Issue: 4
Pages: 777-787
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Publication
23913923 | J:199357
First Author: Kitade M
Year: 2013
Journal: Genes Dev
Title: Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling.
Volume: 27
Issue: 15
Pages: 1706-17
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Publication
27105606 | J:317368
First Author: Falodah FA
Year: 2016
Journal: Tissue Cell
Title: Immuno- and gene expression analysis of EGFR and Nestin during mice skin development.
Volume: 48
Issue: 3
Pages: 274-81
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Publication
23015591 | J:225082
First Author: Zhang LJ
Year: 2012
Journal: J Cell Sci
Title: Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling.
Volume: 125
Issue: Pt 23
Pages: 5733-44
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Publication
22371560 | J:182242
First Author: Sousa LP
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane.
Volume: 109
Issue: 12
Pages: 4419-24
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Publication
25918388 | J:221411
First Author: Li X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Volume: 112
Issue: 19
Pages: 6080-5
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Publication
22785133 | J:191692
First Author: Liu W
Year: 2012
Journal: J Invest Dermatol
Title: Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration.
Volume: 132
Issue: 12
Pages: 2828-37
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Publication
31122699 | J:291195
First Author: Zhang SJ
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific PTEN and EGFR dysfunctions affect neuromuscular junction development by impairing Agrin signaling and autophagy.
Volume: 515
Issue: 1
Pages: 50-56
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Publication
23638043 | J:200550
First Author: Le Pichon CE
Year: 2013
Journal: PLoS One
Title: EGFR inhibitor erlotinib delays disease progression but does not extend survival in the SOD1 mouse model of ALS.
Volume: 8
Issue: 4
Pages: e62342
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Publication
29058721 | J:246200
First Author: Löf-Öhlin ZM
Year: 2017
Journal: Nat Cell Biol
Title: EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity.
Volume: 19
Issue: 11
Pages: 1313-1325
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Publication
36915679 | J:334091
First Author: Zhang X
Year: 2023
Journal: iScience
Title: Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain.
Volume: 26
Issue: 3
Pages: 106242
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Publication
20628198 | J:163773
First Author: Murthy A
Year: 2010
Journal: J Clin Invest
Title: Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice.
Volume: 120
Issue: 8
Pages: 2731-44
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Publication
15020428 | J:88776
First Author: Du X
Year: 2004
Journal: Genetics
Title: Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice.
Volume: 166
Issue: 1
Pages: 331-40
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Publication
25623042 | J:309411
First Author: Chen NM
Year: 2015
Journal: Gastroenterology
Title: NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.
Volume: 148
Issue: 5
Pages: 1024-1034.e9
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Publication
23966299 | J:213463
First Author: Mascia F
Year: 2013
Journal: Sci Transl Med
Title: Genetic ablation of epidermal EGFR reveals the dynamic origin of adverse effects of anti-EGFR therapy.
Volume: 5
Issue: 199
Pages: 199ra110
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Publication
17822758 | J:141339
First Author: Dackor J
Year: 2007
Journal: Placenta
Title: Altered trophoblast proliferation is insufficient to account for placental dysfunction in Egfr null embryos.
Volume: 28
Issue: 11-12
Pages: 1211-8
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Publication
33322301 | J:310557
 
First Author: Zhang X
Year: 2020
Journal: Cells
Title: Clonal Analysis of Gliogenesis in the Cerebral Cortex Reveals Stochastic Expansion of Glia and Cell Autonomous Responses to Egfr Dosage.
Volume: 9
Issue: 12
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Publication
27152417 | J:246760
First Author: Currier MG
Year: 2016
Journal: PLoS Pathog
Title: EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression.
Volume: 12
Issue: 5
Pages: e1005622
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Publication
11161793 | J:66986
First Author: Reiter JL
Year: 2001
Journal: Genomics
Title: Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms.
Volume: 71
Issue: 1
Pages: 1-20
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Publication
34168192 | J:311669
First Author: Stroedecke K
Year: 2021
Journal: Sci Rep
Title: The mineralocorticoid receptor leads to increased expression of EGFR and T-type calcium channels that support HL-1 cell hypertrophy.
Volume: 11
Issue: 1
Pages: 13229
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Publication
14697673 | J:87199
First Author: Boockvar JA
Year: 2003
Journal: Mol Cell Neurosci
Title: Constitutive EGFR signaling confers a motile phenotype to neural stem cells.
Volume: 24
Issue: 4
Pages: 1116-30
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Publication
28790147 | J:321789
First Author: Traxl A
Year: 2017
Journal: Drug Metab Dispos
Title: Hepatocyte-Specific Deletion of EGFR in Mice Reduces Hepatic Abcg2 Transport Activity Measured by [11C]erlotinib and Positron Emission Tomography.
Volume: 45
Issue: 10
Pages: 1093-1100
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Publication
21653642 | J:205224
First Author: Zhu H
Year: 2011
Journal: Mol Cancer Res
Title: EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators.
Volume: 9
Issue: 7
Pages: 960-75
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Publication
32931498 | J:296037
First Author: Onufer EJ
Year: 2020
Journal: PLoS One
Title: EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis.
Volume: 15
Issue: 9
Pages: e0236964
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Publication
26204818 | J:226273
 
First Author: Tang Y
Year: 2015
Journal: Neuroscience
Title: EGFR signaling upregulates surface expression of the GluN2B-containing NMDA receptor and contributes to long-term potentiation in the hippocampus.
Volume: 304
Pages: 109-21
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Publication
22891338 | J:188574
First Author: Zhu W
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection.
Volume: 109
Issue: 35
Pages: 14194-9
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Publication
15294912 | J:94014
First Author: Moran AE
Year: 2004
Journal: J Biol Chem
Title: Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.
Volume: 279
Issue: 41
Pages: 43261-72
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Publication
32251323 | J:298940
First Author: Meyers N
Year: 2020
Journal: Sci Rep
Title: Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma.
Volume: 10
Issue: 1
Pages: 5241
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Publication
37858681 | J:357762
 
First Author: Wang Y
Year: 2023
Journal: Brain Res Bull
Title: Researches of calcium-activated chloride channel ANO1 intervening amyotrophic lateral sclerosis progression by activating EGFR and CaMKII signaling.
Volume: 204
Pages: 110792
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Publication
24337738 | J:207327
First Author: Zhang Z
Year: 2014
Journal: J Immunol
Title: EGFR signaling blunts allergen-induced IL-6 production and Th17 responses in the skin and attenuates development and relapse of atopic dermatitis.
Volume: 192
Issue: 3
Pages: 859-66
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Publication
33989815 | J:312883
First Author: Niitsu H
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Cell-Autonomous Role of EGFR in Spontaneous Duodenal Tumors in LRIG1 Null Mice.
Volume: 12
Issue: 3
Pages: 1159-1162.e4
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Publication
24496615 | J:221296
First Author: Carrillo-García C
Year: 2014
Journal: Development
Title: Growth/differentiation factor 15 promotes EGFR signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice.
Volume: 141
Issue: 4
Pages: 773-83
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Publication
32179676 | J:290061
First Author: Knoop KA
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Maternal activation of the EGFR prevents translocation of gut-residing pathogenic Escherichia coli in a model of late-onset neonatal sepsis.
Volume: 117
Issue: 14
Pages: 7941-7949
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Publication
26341921 | J:320861
First Author: Pirazzoli V
Year: 2016
Journal: Clin Cancer Res
Title: Afatinib plus Cetuximab Delays Resistance Compared to Single-Agent Erlotinib or Afatinib in Mouse Models of TKI-Naïve EGFR L858R-Induced Lung Adenocarcinoma.
Volume: 22
Issue: 2
Pages: 426-35
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Publication
27267807 | J:232848
First Author: Gore J
Year: 2016
Journal: Cancer Lett
Title: Combined targeting of TGF-β, EGFR and HER2 suppresses lymphangiogenesis and metastasis in a pancreatic cancer model.
Volume: 379
Issue: 1
Pages: 143-53
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Publication
20308550 | J:159321
First Author: Vivanco I
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation.
Volume: 107
Issue: 14
Pages: 6459-64
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Publication
21540290 | J:174898
First Author: Zerrad-Saadi A
Year: 2011
Journal: Endocrinology
Title: GH receptor plays a major role in liver regeneration through the control of EGFR and ERK1/2 activation.
Volume: 152
Issue: 7
Pages: 2731-41
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Publication
23255615 | J:193168
First Author: He S
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: EGFR activity is required for renal tubular cell dedifferentiation and proliferation in a murine model of folic acid-induced acute kidney injury.
Volume: 304
Issue: 4
Pages: F356-66
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Publication
29028997 | J:251906
First Author: Kyohara M
Year: 2017
Journal: Endocrinology
Title: Serum Quantitative Proteomic Analysis Reveals Soluble EGFR To Be a Marker of Insulin Resistance in Male Mice and Humans.
Volume: 158
Issue: 12
Pages: 4152-4164
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Publication
19448146 | J:151100
First Author: Barrick CJ
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice.
Volume: 297
Issue: 1
Pages: H65-75
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Publication
25414100 | J:223876
First Author: Scheving LA
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Loss of hepatocyte EGFR has no effect alone but exacerbates carbon tetrachloride-induced liver injury and impairs regeneration in hepatocyte Met-deficient mice.
Volume: 308
Issue: 5
Pages: G364-77
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Publication
30354220 | J:285069
First Author: Carnevale D
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of EMILIN-1 Enhances Arteriolar Myogenic Tone Through TGF-β (Transforming Growth Factor-β)-Dependent Transactivation of EGFR (Epidermal Growth Factor Receptor) and Is Relevant for Hypertension in Mice and Humans.
Volume: 38
Issue: 10
Pages: 2484-2497
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Publication
9030684 | J:38321
First Author: Wang DZ
Year: 1997
Journal: Genes Dev
Title: Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development.
Volume: 11
Issue: 3
Pages: 309-20
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Publication
33826887 | J:317399
First Author: van der Post S
Year: 2021
Journal: Cell Rep
Title: NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation.
Volume: 35
Issue: 1
Pages: 108949
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Protein Domain
IPR021633 | Argos
Type: Family
Description: Argos is a natural secreted antagonist of EGFR signalling which functions by binding growth factor ligands that activate EGFR by forming a clamp like structure using three disulphide-bonded β-sheet domains [].
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Publication
1426645 | J:32190
First Author: Dardik A
Year: 1992
Journal: Dev Biol
Title: Colocalization of transforming growth factor-alpha and a functional epidermal growth factor receptor (EGFR) to the inner cell mass and preferential localization of the EGFR on the basolateral surface of the trophectoderm in the mouse blastocyst.
Volume: 154
Issue: 2
Pages: 396-409
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Publication
25375038 | J:219654
First Author: Liu X
Year: 2015
Journal: Endocrinology
Title: ErbB receptor-driven prolactinomas respond to targeted lapatinib treatment in female transgenic mice.
Volume: 156
Issue: 1
Pages: 71-9
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Publication
36868238 | J:334507
First Author: Ji ML
Year: 2023
Journal: Am J Hum Genet
Title: Dynamic chromatin accessibility tuning by the long noncoding RNA ELDR accelerates chondrocyte senescence and osteoarthritis.
Volume: 110
Issue: 4
Pages: 606-624
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Publication
21987724 | J:178765
First Author: Acquaviva J
Year: 2011
Journal: Cancer Res
Title: Chronic activation of wild-type epidermal growth factor receptor and loss of Cdkn2a cause mouse glioblastoma formation.
Volume: 71
Issue: 23
Pages: 7198-206
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Publication
27507810 | J:318695
First Author: Zhao G
Year: 2016
Journal: J Biol Chem
Title: Activation of Epidermal Growth Factor Receptor in Macrophages Mediates Feedback Inhibition of M2 Polarization and Gastrointestinal Tumor Cell Growth.
Volume: 291
Issue: 39
Pages: 20462-72
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Publication
20060271 | J:161737
First Author: Sugawara K
Year: 2010
Journal: J Dermatol Sci
Title: Cutaneous consequences of inhibiting EGF receptor signaling in vivo: normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in Egfr(Wa5) mice.
Volume: 57
Issue: 3
Pages: 155-61
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Publication
23899604 | J:204096
First Author: Dahlhoff M
Year: 2013
Journal: Biochim Biophys Acta
Title: Increased activation of the epidermal growth factor receptor in transgenic mice overexpressing epigen causes peripheral neuropathy.
Volume: 1832
Issue: 12
Pages: 2068-76
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Publication
21914800 | J:178165
First Author: Dahlhoff M
Year: 2011
Journal: J Biol Chem
Title: In vivo evidence for epidermal growth factor receptor (EGFR)-mediated release of prolactin from the pituitary gland.
Volume: 286
Issue: 45
Pages: 39297-306
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ncRNA Gene
MGI:1919985 | Eldr
Type: lncRNA_gene
Organism: mouse, laboratory
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Publication
31671073 | J:295396
First Author: Bousquet Mur E
Year: 2020
Journal: J Clin Invest
Title: Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma.
Volume: 130
Issue: 2
Pages: 612-624
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Publication
24891618 | J:223674
First Author: Dahlhoff M
Year: 2014
Journal: Mol Cell Biol
Title: Overexpression of epigen during embryonic development induces reversible, epidermal growth factor receptor-dependent sebaceous gland hyperplasia.
Volume: 34
Issue: 16
Pages: 3086-95
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Publication
22056328 | J:180190
First Author: Schneider MR
Year: 2012
Journal: Bone
Title: Normal epidermal growth factor receptor signaling is dispensable for bone anabolic effects of parathyroid hormone.
Volume: 50
Issue: 1
Pages: 237-44
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Publication
15366372 | J:92308
First Author: Lee D
Year: 2004
Journal: Mamm Genome
Title: Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor.
Volume: 15
Issue: 7
Pages: 525-36
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Publication
21887704 | J:233288
First Author: Zhang X
Year: 2011
Journal: J Bone Miner Res
Title: The critical role of the epidermal growth factor receptor in endochondral ossification.
Volume: 26
Issue: 11
Pages: 2622-33
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Publication
7489711 | J:65031
First Author: Murillas R
Year: 1995
Journal: EMBO J
Title: Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure.
Volume: 14
Issue: 21
Pages: 5216-23
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Publication
12925580 | J:84870
First Author: Sibilia M
Year: 2003
Journal: Development
Title: Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart.
Volume: 130
Issue: 19
Pages: 4515-25
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Publication
36657561 | J:333112
 
First Author: Kleczko EK
Year: 2023
Journal: Cancer Lett
Title: Novel EGFR-mutant mouse models of lung adenocarcinoma reveal adaptive immunity requirement for durable osimertinib response.
Volume: 556
Pages: 216062
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Publication
31456099 | J:352848
First Author: Hedegger K
Year: 2020
Journal: J Gastroenterol
Title: The protective effect of betacellulin against acute pancreatitis is ERBB4 dependent.
Volume: 55
Issue: 3
Pages: 317-329
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Publication
22579588 | J:185126
First Author: Dahlhoff M
Year: 2012
Journal: Biochim Biophys Acta
Title: A new mouse model for studying EGFR-dependent gastric polyps.
Volume: 1822
Issue: 8
Pages: 1293-9
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Publication
24047892 | J:204897
First Author: Zhang X
Year: 2013
Journal: J Biol Chem
Title: Epidermal growth factor receptor (EGFR) signaling regulates epiphyseal cartilage development through β-catenin-dependent and -independent pathways.
Volume: 288
Issue: 45
Pages: 32229-40
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Publication
25735773 | J:224241
First Author: Maity TK
Year: 2015
Journal: Cancer Discov
Title: Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma.
Volume: 5
Issue: 5
Pages: 534-49
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Publication
21542005 | J:184353
First Author: Zhang X
Year: 2011
Journal: J Bone Miner Res
Title: Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo.
Volume: 26
Issue: 5
Pages: 1022-34
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Publication
19564486 | J:153156
First Author: Dackor J
Year: 2009
Journal: Genetics
Title: Placental and embryonic growth restriction in mice with reduced function epidermal growth factor receptor alleles.
Volume: 183
Issue: 1
Pages: 207-18
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Publication
18556782 | J:137366
First Author: Schneider MR
Year: 2008
Journal: Am J Pathol
Title: Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology.
Volume: 173
Issue: 1
Pages: 14-24
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Publication
27251290 | J:235747
First Author: Jia Y
Year: 2016
Journal: Nature
Title: Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors.
Volume: 534
Issue: 7605
Pages: 129-32
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Publication
- | J:231805
     
First Author: SoRelle J
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for set
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Publication
29024567 | J:272171
First Author: Jia H
Year: 2018
Journal: Arthritis Rheumatol
Title: Loading-Induced Reduction in Sclerostin as a Mechanism of Subchondral Bone Plate Sclerosis in Mouse Knee Joints During Late-Stage Osteoarthritis.
Volume: 70
Issue: 2
Pages: 230-241
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Publication
23019586 | J:190314
First Author: Wang L
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Epidermal growth factor receptor is a preferred target for treating amyloid-β-induced memory loss.
Volume: 109
Issue: 41
Pages: 16743-8
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Publication
18656477 | J:138998
First Author: Dahlhoff M
Year: 2008
Journal: FEBS Lett
Title: Betacellulin stimulates growth of the mouse intestinal epithelium and increases adenoma multiplicity in Apc+/Min mice.
Volume: 582
Issue: 19
Pages: 2911-5
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Publication
11929848 | J:75964
First Author: Thaung C
Year: 2002
Journal: Hum Mol Genet
Title: Novel ENU-induced eye mutations in the mouse: models for human eye disease.
Volume: 11
Issue: 7
Pages: 755-67
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Publication
10943841 | J:63426
First Author: Sibilia M
Year: 2000
Journal: Cell
Title: The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development.
Volume: 102
Issue: 2
Pages: 211-20
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Publication
24079739 | J:220416
First Author: Dahlhoff M
Year: 2013
Journal: Exp Dermatol
Title: Ligand-independent epidermal growth factor receptor hyperactivation increases sebaceous gland size and sebum secretion in mice.
Volume: 22
Issue: 10
Pages: 667-9
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Publication
38896614 | J:349902
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Gene
312812 | Eps8
Type: gene
Organism: rat
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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