Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The TRPM subfamily of mammalian TRP channels includes TRPM8, which is a cold- and menthol-activated ion channel expressed in peripheral sensory neurons, where it plays a critical role in cold temperature detection []. TRPM8 is also found in the prostate and is up-regulated in prostate cancer and other malignancies []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388611 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-12-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7388631 |
Age: |
postnatal day 30 |
Image: |
4D TRPM8 Control |
|
Specimen Label: |
4D TRPM8 Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388611 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-12-02 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7388631 |
Age: |
postnatal day 30 |
Image: |
4D TRPM8 Tlx3 CKO |
Note: |
Expression reduced by 45% compared to control. |
Specimen Label: |
4D TRPM8 Tlx3 CKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388611 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-12-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667824 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:7388631 |
Age: |
embryonic day 16.5 |
Image: |
5A TRPM8 E16.5 Control |
|
Specimen Label: |
5A TRPM8 E16.5 Control |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388611 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-12-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667824 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:7388631 |
Age: |
embryonic day 16.5 |
Image: |
5A TRPM8 E16.5 Tlx3-/- |
Note: |
Expression still detected at E16.5. |
Specimen Label: |
5A TRPM8 E16.5 Tlx3-/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388611 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-12-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667827 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7388631 |
Age: |
postnatal day 0 |
Image: |
5A TRPM8 P0 Control |
|
Specimen Label: |
5A TRPM8 P0 Control |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388611 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-12-02 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:3667827 |
Pattern: |
Single cells |
Stage: |
TS27 |
Assay Id: |
MGI:7388631 |
Age: |
postnatal day 0 |
Image: |
5A TRPM8 P0 Tlx3-/- |
Note: |
Expression greatly reduced at P0. Weak expression in neurons |
Specimen Label: |
5A TRPM8 P0 Tlx3-/- |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484578 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7484630 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5d TRPM8 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Almaraz L |
Year: |
2014 |
Journal: |
Handb Exp Pharmacol |
Title: |
TRPM8. |
Volume: |
222 |
|
Pages: |
547-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsavaler L |
Year: |
2001 |
Journal: |
Cancer Res |
Title: |
Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. |
Volume: |
61 |
Issue: |
9 |
Pages: |
3760-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Colburn RW |
Year: |
2007 |
Journal: |
Neuron |
Title: |
Attenuated cold sensitivity in TRPM8 null mice. |
Volume: |
54 |
Issue: |
3 |
Pages: |
379-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morenilla-Palao C |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Lipid raft segregation modulates TRPM8 channel activity. |
Volume: |
284 |
Issue: |
14 |
Pages: |
9215-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramachandran R |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
TRPM8 activation attenuates inflammatory responses in mouse models of colitis. |
Volume: |
110 |
Issue: |
18 |
Pages: |
7476-81 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1104
![FASTA](model/images/fasta.gif;jsessionid=62AE358E860C85A92D7FA049DDD1F1FD) |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Dhaka A |
Year: |
2007 |
Journal: |
Neuron |
Title: |
TRPM8 is required for cold sensation in mice. |
Volume: |
54 |
Issue: |
3 |
Pages: |
371-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramos-Filho AC |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Menthol inhibits detrusor contractility independently of TRPM8 activation. |
Volume: |
9 |
Issue: |
11 |
Pages: |
e111616 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gkika D |
Year: |
2015 |
Journal: |
J Cell Biol |
Title: |
TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity. |
Volume: |
208 |
Issue: |
1 |
Pages: |
89-107 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484578 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7484630 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5a TRPM8 Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484578 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-26 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7484630 |
Age: |
postnatal adult |
|
Note: |
Number of expressing neurons unaffected but expression level reduced compared with control |
Specimen Label: |
5a TRPM8 PN-ZB20KO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484587 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-05-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7484643 |
Age: |
postnatal adult |
|
|
Specimen Label: |
4 TRPM8 Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484587 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-05-26 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7484643 |
Age: |
postnatal adult |
|
Note: |
Percentage of expressing neurons not significantly changed, but expression intensity weaker than control. |
Specimen Label: |
4 TRPM8 PN-ZB20KO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arcas JM |
Year: |
2019 |
Journal: |
J Neurosci |
Title: |
The Immunosuppressant Macrolide Tacrolimus Activates Cold-Sensing TRPM8 Channels. |
Volume: |
39 |
Issue: |
6 |
Pages: |
949-969 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCoy DD |
Year: |
2013 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Enhanced insulin clearance in mice lacking TRPM8 channels. |
Volume: |
305 |
Issue: |
1 |
Pages: |
E78-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klasen K |
Year: |
2012 |
Journal: |
Pflugers Arch |
Title: |
The TRPM8 ion channel comprises direct Gq protein-activating capacity. |
Volume: |
463 |
Issue: |
6 |
Pages: |
779-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tajino K |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Cooling-sensitive TRPM8 is thermostat of skin temperature against cooling. |
Volume: |
6 |
Issue: |
3 |
Pages: |
e17504 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2012 |
Journal: |
Nat Cell Biol |
Title: |
Direct inhibition of the cold-activated TRPM8 ion channel by Gαq. |
Volume: |
14 |
Issue: |
8 |
Pages: |
851-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quallo T |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
TRPM8 is a neuronal osmosensor that regulates eye blinking in mice. |
Volume: |
6 |
|
Pages: |
7150 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cornejo VH |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Non-conventional Axonal Organelles Control TRPM8 Ion Channel Trafficking and Peripheral Cold Sensing. |
Volume: |
30 |
Issue: |
13 |
Pages: |
4505-4517.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bautista DM |
Year: |
2007 |
Journal: |
Nature |
Title: |
The menthol receptor TRPM8 is the principal detector of environmental cold. |
Volume: |
448 |
Issue: |
7150 |
Pages: |
204-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ordás P |
Year: |
2021 |
Journal: |
J Comp Neurol |
Title: |
Expression of the cold thermoreceptor TRPM8 in rodent brain thermoregulatory circuits. |
Volume: |
529 |
Issue: |
1 |
Pages: |
234-256 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takashima Y |
Year: |
2010 |
Journal: |
Neuroscience |
Title: |
The development of peripheral cold neural circuits based on TRPM8 expression. |
Volume: |
169 |
Issue: |
2 |
Pages: |
828-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chan H |
Year: |
2018 |
Journal: |
Oncotarget |
Title: |
TRPM8 and RAAS-mediated hypertension is critical for cold-induced immunosuppression in mice. |
Volume: |
9 |
Issue: |
16 |
Pages: |
12781-12795 |
|
•
•
•
•
•
|
Publication |
First Author: |
Michot B |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
TRPM8 and TRPA1 do not contribute to dental pulp sensitivity to cold. |
Volume: |
8 |
Issue: |
1 |
Pages: |
13198 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moraes MN |
Year: |
2017 |
Journal: |
Biochim Biophys Acta |
Title: |
Cold-sensing TRPM8 channel participates in circadian control of the brown adipose tissue. |
Volume: |
1864 |
Issue: |
12 |
Pages: |
2415-2427 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ran L |
Year: |
2023 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice. |
Volume: |
64 |
Issue: |
1 |
Pages: |
19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lelis Carvalho A |
Year: |
2021 |
Journal: |
PLoS One |
Title: |
TRPM8 modulates temperature regulation in a sex-dependent manner without affecting cold-induced bone loss. |
Volume: |
16 |
Issue: |
6 |
Pages: |
e0231060 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hernández-Ortego P |
Year: |
2022 |
Journal: |
Int J Mol Sci |
Title: |
Validation of Six Commercial Antibodies for the Detection of Heterologous and Endogenous TRPM8 Ion Channel Expression. |
Volume: |
23 |
Issue: |
24 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dragoni I |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
The cold and menthol receptor TRPM8 contains a functionally important double cysteine motif. |
Volume: |
281 |
Issue: |
49 |
Pages: |
37353-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ota W |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Involvement of TRPM2 and TRPM8 in temperature-dependent masking behavior. |
Volume: |
9 |
Issue: |
1 |
Pages: |
3706 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma S |
Year: |
2012 |
Journal: |
J Mol Cell Biol |
Title: |
Activation of the cold-sensing TRPM8 channel triggers UCP1-dependent thermogenesis and prevents obesity. |
Volume: |
4 |
Issue: |
2 |
Pages: |
88-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brenner DS |
Year: |
2014 |
Journal: |
Pain |
Title: |
A dynamic set point for thermal adaptation requires phospholipase C-mediated regulation of TRPM8 in vivo. |
Volume: |
155 |
Issue: |
10 |
Pages: |
2124-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morenilla-Palao C |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
Ion channel profile of TRPM8 cold receptors reveals a role of TASK-3 potassium channels in thermosensation. |
Volume: |
8 |
Issue: |
5 |
Pages: |
1571-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
Direct Gαq Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation. |
Volume: |
27 |
Issue: |
12 |
Pages: |
3672-3683.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mueller-Tribbensee SM |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice. |
Volume: |
10 |
Issue: |
7 |
Pages: |
e0128242 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bidaux G |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Epidermal TRPM8 channel isoform controls the balance between keratinocyte proliferation and differentiation in a cold-dependent manner. |
Volume: |
112 |
Issue: |
26 |
Pages: |
E3345-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Almeida MC |
Year: |
2012 |
Journal: |
J Neurosci |
Title: |
Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature. |
Volume: |
32 |
Issue: |
6 |
Pages: |
2086-99 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujita T |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins. |
Volume: |
495 |
Issue: |
1 |
Pages: |
935-940 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mohandass A |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
TRPM8 as the rapid testosterone signaling receptor: Implications in the regulation of dimorphic sexual and social behaviors. |
Volume: |
34 |
Issue: |
8 |
Pages: |
10887-10906 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Jong PR |
Year: |
2015 |
Journal: |
Mucosal Immunol |
Title: |
TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP. |
Volume: |
8 |
Issue: |
3 |
Pages: |
491-504 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borowiec AS |
Year: |
2016 |
Journal: |
FASEB J |
Title: |
Cold/menthol TRPM8 receptors initiate the cold-shock response and protect germ cells from cold-shock-induced oxidation. |
Volume: |
30 |
Issue: |
9 |
Pages: |
3155-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Madrid R |
Year: |
2009 |
Journal: |
J Neurosci |
Title: |
Variable threshold of trigeminal cold-thermosensitive neurons is determined by a balance between TRPM8 and Kv1 potassium channels. |
Volume: |
29 |
Issue: |
10 |
Pages: |
3120-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vanden Abeele F |
Year: |
2013 |
Journal: |
J Cell Sci |
Title: |
Complex modulation of the cold receptor TRPM8 by volatile anaesthetics and its role in complications of general anaesthesia. |
Volume: |
126 |
Issue: |
Pt 19 |
Pages: |
4479-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang D |
Year: |
2012 |
Journal: |
Mol Pain |
Title: |
Expression of the transient receptor potential channels TRPV1, TRPA1 and TRPM8 in mouse trigeminal primary afferent neurons innervating the dura. |
Volume: |
8 |
|
Pages: |
66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feketa VV |
Year: |
2013 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibition. |
Volume: |
305 |
Issue: |
9 |
Pages: |
R1040-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reimúndez A |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Deletion of the Cold Thermoreceptor TRPM8 Increases Heat Loss and Food Intake Leading to Reduced Body Temperature and Obesity in Mice. |
Volume: |
38 |
Issue: |
15 |
Pages: |
3643-3656 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schecterson LC |
Year: |
2020 |
Journal: |
Mol Vis |
Title: |
TRPV1, TRPA1, and TRPM8 are expressed in axon terminals in the cornea: TRPV1 axons contain CGRP and secretogranin II; TRPA1 axons contain secretogranin 3. |
Volume: |
26 |
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Pages: |
576-587 |
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Gene |
Type: |
gene |
Organism: |
human |
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Gene |
Type: |
gene |
Organism: |
human |
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Publication |
First Author: |
Bouvier V |
Year: |
2018 |
Journal: |
J Invest Dermatol |
Title: |
Merkel Cells Sense Cooling with TRPM8Â Channels. |
Volume: |
138 |
Issue: |
4 |
Pages: |
946-956 |
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Publication |
First Author: |
Kim YS |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Central connectivity of transient receptor potential melastatin 8-expressing axons in the brain stem and spinal dorsal horn. |
Volume: |
9 |
Issue: |
4 |
Pages: |
e94080 |
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Publication |
First Author: |
Kim YS |
Year: |
2015 |
Journal: |
Neuroscience |
Title: |
Expression of vesicular glutamate transporters in transient receptor potential melastatin 8 (TRPM8)-positive dental afferents in the mouse. |
Volume: |
303 |
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Pages: |
378-88 |
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Publication |
First Author: |
Knowlton WM |
Year: |
2013 |
Journal: |
J Neurosci |
Title: |
A sensory-labeled line for cold: TRPM8-expressing sensory neurons define the cellular basis for cold, cold pain, and cooling-mediated analgesia. |
Volume: |
33 |
Issue: |
7 |
Pages: |
2837-48 |
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Publication |
First Author: |
Matos-Cruz V |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters. |
Volume: |
21 |
Issue: |
12 |
Pages: |
3329-3337 |
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Publication |
First Author: |
Ongun S |
Year: |
2018 |
Journal: |
Commun Biol |
Title: |
Selective cold pain inhibition by targeted block of TRPM8-expressing neurons with quaternary lidocaine derivative QX-314. |
Volume: |
1 |
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Pages: |
53 |
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Publication |
First Author: |
Shapovalov G |
Year: |
2013 |
Journal: |
Cell Rep |
Title: |
Opiates modulate thermosensation by internalizing cold receptor TRPM8. |
Volume: |
4 |
Issue: |
3 |
Pages: |
504-15 |
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Publication |
First Author: |
Horikawa R |
Year: |
2022 |
Journal: |
Neurosci Lett |
Title: |
Effects of peripheral administration of lipopolysaccharide on chronic sickness responses in TRPM8-deficient mice. |
Volume: |
790 |
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Pages: |
136895 |
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Publication |
First Author: |
Gong K |
Year: |
2017 |
Journal: |
J Pain |
Title: |
Sustained Morphine Administration Induces TRPM8-Dependent Cold Hyperalgesia. |
Volume: |
18 |
Issue: |
2 |
Pages: |
212-221 |
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Publication |
First Author: |
Khalil M |
Year: |
2016 |
Journal: |
Mucosal Immunol |
Title: |
Transient receptor potential melastatin 8 ion channel in macrophages modulates colitis through a balance-shift in TNF-alpha and interleukin-10 production. |
Volume: |
9 |
Issue: |
6 |
Pages: |
1500-1513 |
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Publication |
First Author: |
Robbins A |
Year: |
2012 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Menthol activation of corneal cool cells induces TRPM8-mediated lacrimation but not nociceptive responses in rodents. |
Volume: |
53 |
Issue: |
11 |
Pages: |
7034-42 |
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Publication |
First Author: |
Tsuneoka Y |
Year: |
2023 |
Journal: |
Neurosci Lett |
Title: |
Characterization of TRPM8-expressing neurons in the adult mouse hypothalamus. |
Volume: |
814 |
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Pages: |
137463 |
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Publication |
First Author: |
Moriyama H |
Year: |
2021 |
Journal: |
Front Pharmacol |
Title: |
Suppressive Effects of Transient Receptor Potential Melastatin 8 Agonist on Epileptiform Discharges and Epileptic Seizures. |
Volume: |
12 |
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Pages: |
766782 |
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Publication |
First Author: |
Dhaka A |
Year: |
2008 |
Journal: |
J Neurosci |
Title: |
Visualizing cold spots: TRPM8-expressing sensory neurons and their projections. |
Volume: |
28 |
Issue: |
3 |
Pages: |
566-75 |
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Publication |
First Author: |
Pezzoli M |
Year: |
2014 |
Journal: |
Sci Rep |
Title: |
Dampened neural activity and abolition of epileptic-like activity in cortical slices by active ingredients of spices. |
Volume: |
4 |
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Pages: |
6825 |
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Publication |
First Author: |
Beukema P |
Year: |
2018 |
Journal: |
J Comp Neurol |
Title: |
TrpM8-mediated somatosensation in mouse neocortex. |
Volume: |
526 |
Issue: |
9 |
Pages: |
1444-1456 |
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Publication |
First Author: |
Moriyama H |
Year: |
2023 |
Journal: |
Front Pharmacol |
Title: |
Suppressive effects of a transient receptor potential melastatin 8 (TRPM8) agonist on hyperthermia-induced febrile seizures in infant mice. |
Volume: |
14 |
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Pages: |
1138673 |
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Publication |
First Author: |
Caudle RM |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Sex differences in mouse Transient Receptor Potential Cation Channel, Subfamily M, Member 8 expressing trigeminal ganglion neurons. |
Volume: |
12 |
Issue: |
5 |
Pages: |
e0176753 |
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Publication |
First Author: |
Tang Z |
Year: |
2013 |
Journal: |
Nat Commun |
Title: |
Pirt functions as an endogenous regulator of TRPM8. |
Volume: |
4 |
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Pages: |
2179 |
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Publication |
First Author: |
Ghosh D |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
VAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8. |
Volume: |
7 |
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Pages: |
10489 |
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Publication |
First Author: |
Gkika D |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
Testosterone-androgen receptor: The steroid link inhibiting TRPM8-mediated cold sensitivity. |
Volume: |
34 |
Issue: |
6 |
Pages: |
7483-7499 |
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Publication |
First Author: |
Janssens A |
Year: |
2016 |
Journal: |
Elife |
Title: |
Definition of two agonist types at the mammalian cold-activated channel TRPM8. |
Volume: |
5 |
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Publication |
First Author: |
Mandadi S |
Year: |
2009 |
Journal: |
Neuroscience |
Title: |
Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels. |
Volume: |
162 |
Issue: |
4 |
Pages: |
1377-97 |
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Publication |
First Author: |
Vetter I |
Year: |
2013 |
Journal: |
J Neurosci |
Title: |
Amplified cold transduction in native nociceptors by M-channel inhibition. |
Volume: |
33 |
Issue: |
42 |
Pages: |
16627-41 |
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Publication |
First Author: |
Memon T |
Year: |
2017 |
Journal: |
Neuroscience |
Title: |
TRPA1 expression levels and excitability brake by KV channels influence cold sensitivity of TRPA1-expressing neurons. |
Volume: |
353 |
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Pages: |
76-86 |
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Publication |
First Author: |
Lemon CH |
Year: |
2019 |
Journal: |
eNeuro |
Title: |
The TRPA1 Ion Channel Contributes to Sensory-Guided Avoidance of Menthol in Mice. |
Volume: |
6 |
Issue: |
6 |
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Publication |
First Author: |
Wang S |
Year: |
2017 |
Journal: |
EMBO Mol Med |
Title: |
A clinical and mechanistic study of topical borneol-induced analgesia. |
Volume: |
9 |
Issue: |
6 |
Pages: |
802-815 |
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Publication |
First Author: |
Gibbs GM |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Cysteine-rich secretory protein 4 is an inhibitor of transient receptor potential M8 with a role in establishing sperm function. |
Volume: |
108 |
Issue: |
17 |
Pages: |
7034-9 |
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Publication |
First Author: |
McCoy ES |
Year: |
2014 |
Journal: |
Mol Pain |
Title: |
Enhanced behavioral responses to cold stimuli following CGRPα sensory neuron ablation are dependent on TRPM8. |
Volume: |
10 |
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Pages: |
69 |
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Publication |
First Author: |
Peier AM |
Year: |
2002 |
Journal: |
Cell |
Title: |
A TRP channel that senses cold stimuli and menthol. |
Volume: |
108 |
Issue: |
5 |
Pages: |
705-15 |
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