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Search results 1301 to 1349 out of 1349 for Aqp1

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0.019s

Type

Details

Score

GXD Expression

Probe:	MGI:4868277
Assay Type:	RNA in situ
Annotation Date:	2014-02-07
Strength:	Present
Sex:	Female
Emaps:	EMAPS:2804923
Pattern:	Regionally restricted
Stage:	TS23
Assay Id:	MGI:5540919
Age:	embryonic day 15.5
Image:	GUDMAP:10913
Note:	distal expression; expression likely restricted to the distal portion of the immature loop of Henle representative of early thin ascending loop of Henle as there is no overlap in expression with Aqp1 which is thin descending loop.
Specimen Label:	GUDMAP:10913
Detected:	true
Specimen Num:	5

•

GXD Expression

Probe:	MGI:1371571
Assay Type:	RNA in situ
Annotation Date:	2014-02-07
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:2804923
Pattern:	Regionally restricted
Stage:	TS23
Assay Id:	MGI:5538830
Age:	embryonic day 15.5
Image:	GUDMAP:10916
Note:	expression in a subset of immature loop of Henle some with overlapping expression with Aqp1, some not overlapping with Aqp1 and some loop of Henle absent for both Aqp1 and Spp1.
Specimen Label:	GUDMAP:10916
Detected:	true
Specimen Num:	3

•

GXD Expression

Probe:	MGI:5001058
Assay Type:	RNA in situ
Annotation Date:	2014-02-07
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:2800323
Pattern:	Regionally restricted
Stage:	TS23
Assay Id:	MGI:5541615
Age:	embryonic day 15.5
Image:	GUDMAP:10917
Note:	distal expression; strong Napsa mRNA expression in subset of early proximal tubules of maturing nephron stage IV only which overlap with Aqp1 early proximal tubule expression. Napsa expression in the early S2 and S3 segments of the early proximal tubule ie. regional expression adjacent to the immature loop of Henle or most distal early proximal tubules.
Specimen Label:	GUDMAP:10917
Detected:	true
Specimen Num:	1

•

Publication

18606867 | J:140244

First Author:	Okada S
Year:	2008
Journal:	FASEB J
Title:	Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation.
Volume:	22
Issue:	10
Pages:	3672-84

•

Protein Domain

IPR023266 | Aquaporin_11

Type:

Family

Description:

The aquaporins (AQPs) are a family of integral membrane proteins composed of two subfamilies: the orthodox aquaporins, which transport only water, and the aquaglyceroporins, which transport glycerol, urea, or other small solutes []. AQP1 in pleural mesothelial cells participate in the formation of pleural fluid [], renal AQP2 is involved in levels of solutes []and changes in AQP9 in the hippocampus are related to delayed neuronal death []. Aquaporins contain two tandem repeats, each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).Aquaporin-11 (AQP11) and aquaporin-12 belong to a new aquaporin subfamily termed superaquaporins []. AQP11 is found in the endoplasmic reticulum and has been connected to policystic kidney disease through knock-out experiments []. It has also been shown that although the characteristic NPA motif may not be fully conserved in both tandem repeats, the molecule nevertheless preserves its water-transport function [].

•

Publication

17178102 | J:188552

First Author:	Yakata K
Year:	2007
Journal:	Biochim Biophys Acta
Title:	Aquaporin-11 containing a divergent NPA motif has normal water channel activity.
Volume:	1768
Issue:	3
Pages:	688-93

•

Publication

19096782 | -

First Author:	Ishibashi K
Year:	2009
Journal:	Handb Exp Pharmacol
Title:	New members of mammalian aquaporins: AQP10-AQP12.

Issue:	190
Pages:	251-62

•

Publication

18067818 | -

First Author:	Zhang W
Year:	2007
Journal:	Zhonghua Yi Xue Za Zhi
Title:	[Effect of hypertonic medium on expression of aquaporin-1 in pleural mesothelial cells: experiment with rats].
Volume:	87
Issue:	35
Pages:	2508-11

•

Publication

18419953 | -

First Author:	Wang Y
Year:	2008
Journal:	Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
Title:	[Expression of renal aquaporin 2 after circulatory arrest].
Volume:	20
Issue:	4
Pages:	210-3

•

Publication

17526024 | -

First Author:	Hwang IK
Year:	2007
Journal:	J Neurosci Res
Title:	Aquaporin 9 changes in pyramidal cells before and is expressed in astrocytes after delayed neuronal death in the ischemic hippocampal CA1 region of the gerbil.
Volume:	85
Issue:	11
Pages:	2470-9

•

Publication

15809071 | J:97446

First Author:	Itoh T
Year:	2005
Journal:	Biochem Biophys Res Commun
Title:	Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells.
Volume:	330
Issue:	3
Pages:	832-8

•

Protein Domain

IPR016697 | Aquaporin_11/12

Type:

Family

Description:

The aquaporins (AQPs) are a family of integral membrane proteins composed of two subfamilies: the orthodox aquaporins, which transport only water, and the aquaglyceroporins, which transport glycerol, urea, or other small solutes []. AQP1 in pleural mesothelial cells participate in the formation of pleural fluid [], renal AQP2 is involved in levels of solutes []and changes in AQP9 in the hippocampus are related to delayed neuronal death []. Aquaporins contain two tandem repeats, each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).Aquaporins 11 and 12 are classified as members of a new AQP subfamily: the subcellular AQPs []. AQP 11 and 12 appear to be more distantly related to the other mammalian aquaporins and aquaglyceroporins. AQP11 is functionally distinct from other proteins of the aquaporin superfamily and could represent a new aquaporin subfamily []. In members of the subcellular AQPs, one of the two asparagine-proline-alanine (NPA) motifs are not completely conserved. They play a crucial role in selective water conduction and function as water channels []. This group represents an aquaporin types 11 and 12.

•

Protein Domain

IPR023265 | Aquaporin_12

Type:

Family

Description:

The aquaporins (AQPs) are a family of integral membrane proteins composed of two subfamilies: the orthodox aquaporins, which transport only water, and the aquaglyceroporins, which transport glycerol, urea, or other small solutes []. AQP1 in pleural mesothelial cells participate in the formation of pleural fluid [], renal AQP2 is involved in levels of solutes []and changes in AQP9 in the hippocampus are related to delayed neuronal death []. Aquaporins contain two tandem repeats, each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).Aquaporin-11 and aquaporin-12 (AQP12) belong to a new aquaporin subfamily termed superaquaporins []. AQP12 is exclusively found in pancreatic acinar cells [], and is not localised in the plasma membrane. No specific localisation has yet been established for this subfamily, but its presence in the pancreas implies some role in the secretion of digestive enzymes []and fluids in the pancreatic cells []. A structural characteristic of AQP12 is the lack of a cytoplasmic N-terminal region, by contrast with all other known aquaporins.

•

Publication

19660138 | J:323127

First Author:	Li L
Year:	2009
Journal:	BMC Neurosci
Title:	Greatly attenuated experimental autoimmune encephalomyelitis in aquaporin-4 knockout mice.
Volume:	10

Pages:	94

•

Publication

11705786 | J:73267

First Author:	Virkki LV
Year:	2001
Journal:	Am J Physiol Regul Integr Comp Physiol
Title:	Cloning and functional expression of an MIP (AQP0) homolog from killifish (Fundulus heteroclitus) lens.
Volume:	281
Issue:	6
Pages:	R1994-2003

•

Protein

Q8BYF0

Organism:	Mus musculus/domesticus
Length:	225
Fragment?:	true

•

Protein

A0A0X1KG63

Organism:	Mus musculus/domesticus
Length:	216
Fragment?:	true

•

Publication

10619865 | J:110737

First Author:	Ma T
Year:	2000
Journal:	J Clin Invest
Title:	Lung fluid transport in aquaporin-5 knockout mice.
Volume:	105
Issue:	1
Pages:	93-100

•

Publication

21251984 | J:279944

First Author:	Yakata K
Year:	2011
Journal:	J Struct Biol
Title:	Water permeability and characterization of aquaporin-11.
Volume:	174
Issue:	2
Pages:	315-20

•

Publication

17077387 | J:147631

First Author:	Skowronski MT
Year:	2007
Journal:	Am J Physiol Renal Physiol
Title:	AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolism.
Volume:	292
Issue:	3
Pages:	F956-65

•

Publication

23813972 | J:202267

First Author:	Vilas GL
Year:	2013
Journal:	Hum Mol Genet
Title:	Transmembrane water-flux through SLC4A11: a route defective in genetic corneal diseases.
Volume:	22
Issue:	22
Pages:	4579-90

•

Publication

19332547 | J:150508

First Author:	Tewari N
Year:	2009
Journal:	J Biol Chem
Title:	The water channel aquaporin 1 is a novel molecular target of polychlorinated biphenyls for in utero anomalies.
Volume:	284
Issue:	22
Pages:	15224-32

•

Publication

26822858 | J:323080

First Author:	Madonna R
Year:	2016
Journal:	Cardiovasc Diabetol
Title:	High glucose-induced hyperosmolarity contributes to COX-2 expression and angiogenesis: implications for diabetic retinopathy.
Volume:	15

Pages:	18

•

Publication

20522648 | J:163414

First Author:	Yao C
Year:	2010
Journal:	Am J Pathol
Title:	Potential down-regulation of salivary gland AQP5 by LPS via cross-coupling of NF-kappaB and p-c-Jun/c-Fos.
Volume:	177
Issue:	2
Pages:	724-34

•

Publication

10737773 | J:61675

First Author:	Ma T
Year:	2000
Journal:	Proc Natl Acad Sci U S A
Title:	Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels.
Volume:	97
Issue:	8
Pages:	4386-91

•

Publication

16224116 | J:106039

First Author:	van Erpecum KJ
Year:	2006
Journal:	J Lipid Res
Title:	Gallbladder histopathology during murine gallstone formation: relation to motility and concentrating function.
Volume:	47
Issue:	1
Pages:	32-41

•

Publication

27138166 | J:315579

First Author:	Lim JH
Year:	2016
Journal:	Pflugers Arch
Title:	The effect of AQP3 deficiency on fuel selection during a single bout of exhausting exercise.
Volume:	468
Issue:	7
Pages:	1283-1293

•

Publication

12167603 | J:113545

First Author:	Klein JD
Year:	2002
Journal:	Am J Physiol Renal Physiol
Title:	Impaired urine concentration and absence of tissue ACE: involvement of medullary transport proteins.
Volume:	283
Issue:	3
Pages:	F517-24

•

Publication

11773623 | J:130418

First Author:	Nejsum LN
Year:	2002
Journal:	Proc Natl Acad Sci U S A
Title:	Functional requirement of aquaporin-5 in plasma membranes of sweat glands.
Volume:	99
Issue:	1
Pages:	511-6

•

Publication

22279059 | J:182533

First Author:	Hasegawa A
Year:	2012
Journal:	Blood
Title:	Mature erythrocyte membrane homeostasis is compromised by loss of the GATA1-FOG1 interaction.
Volume:	119
Issue:	11
Pages:	2615-23

•

Publication

34680152 | J:323066

First Author:	Verta R
Year:	2021
Journal:	Biomolecules
Title:	The Interplay between Histamine H₄ Receptor and the Kidney Function: The Lesson from H₄ Receptor Knockout Mice.
Volume:	11
Issue:	10

•

Publication

29251736 | J:277522

First Author:	Nasrallah R
Year:	2018
Journal:	Lab Invest
Title:	PGE₂ EP₁ receptor inhibits vasopressin-dependent water reabsorption and sodium transport in mouse collecting duct.
Volume:	98
Issue:	3
Pages:	360-370

•

Publication

22777185 | J:323030

First Author:	Rutkovskiy A
Year:	2012
Journal:	Basic Res Cardiol
Title:	Aquaporin-4 in the heart: expression, regulation and functional role in ischemia.
Volume:	107
Issue:	5
Pages:	280

•

Publication

16860289 | J:116513

First Author:	Sohara E
Year:	2006
Journal:	Biochim Biophys Acta
Title:	Physiological roles of AQP7 in the kidney: Lessons from AQP7 knockout mice.
Volume:	1758
Issue:	8
Pages:	1106-10

•

Publication

20588253 | J:163386

First Author:	Maruyama T
Year:	2010
Journal:	EMBO J
Title:	CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.
Volume:	29
Issue:	15
Pages:	2501-14

•

Publication

20573687 | J:182857

First Author:	Francone VP
Year:	2010
Journal:	Mol Endocrinol
Title:	Signaling from the secretory granule to the nucleus: Uhmk1 and PAM.
Volume:	24
Issue:	8
Pages:	1543-58

•

Protein

Q8BHH1

Organism:	Mus musculus/domesticus
Length:	271
Fragment?:	false

•

Protein

Q8CHJ2

Organism:	Mus musculus/domesticus
Length:	290
Fragment?:	false

•

Protein

Q3V2I1

Organism:	Mus musculus/domesticus
Length:	289
Fragment?:	false

•

Publication

15033928 | J:118506

First Author:	Frigeri A
Year:	2004
Journal:	FASEB J
Title:	Aquaporins in skeletal muscle: reassessment of the functional role of aquaporin-4.
Volume:	18
Issue:	7
Pages:	905-7

•

Publication

33529207 | J:302275

First Author:	Kimball E
Year:	2021
Journal:	PLoS One
Title:	The role of aquaporin-4 in optic nerve head astrocytes in experimental glaucoma.
Volume:	16
Issue:	2
Pages:	e0244123

•

Publication

31033226 | J:304483

First Author:	Wang H
Year:	2019
Journal:	Physiol Rep
Title:	Sickle cell disease up-regulates vasopressin, aquaporin 2, urea transporter A1, Na-K-Cl cotransporter 2, and epithelial Na channels in the mouse kidney medulla despite compromising urinary concentration ability.
Volume:	7
Issue:	8
Pages:	e14066

•

Publication

29354070 | J:276261

First Author:	Krishnan D
Year:	2017
Journal:	Front Physiol
Title:	Deficiency of Carbonic Anhydrase II Results in a Urinary Concentrating Defect.
Volume:	8

Pages:	1108

•

Publication

11249852 | J:114240

First Author:	Downey P
Year:	2001
Journal:	Am J Physiol Renal Physiol
Title:	Renal concentrating defect in mice lacking group IV cytosolic phospholipase A(2).
Volume:	280
Issue:	4
Pages:	F607-18

•

Publication

22550388 | J:323078

First Author:	Kumari SS
Year:	2012
Journal:	Mol Vis
Title:	Spatial expression of aquaporin 5 in mammalian cornea and lens, and regulation of its localization by phosphokinase A.
Volume:	18

Pages:	957-67

•

Publication

9651190 | J:49365

First Author:	Ma T
Year:	1998
Journal:	Am J Respir Cell Mol Biol
Title:	Evidence against a role of mouse, rat, and two cloned human t1alpha isoforms as a water channel or a regulator of aquaporin-type water channels.
Volume:	19
Issue:	1
Pages:	143-9

•

Publication

19857466 | J:155604

First Author:	Kumari SS
Year:	2009
Journal:	Biochem Biophys Res Commun
Title:	Intact AQP0 performs cell-to-cell adhesion.
Volume:	390
Issue:	3
Pages:	1034-9

•

Publication

39868227 | J:361196

First Author:	Chung E
Year:	2025
Journal:	bioRxiv
Title:	The thin descending limb of the loop of Henle originates from proximal tubule cells during mouse kidney development.

•

Publication

16650285 | -

First Author:	Gorelick DA
Year:	2006
Journal:	BMC Biochem
Title:	Aquaporin-11: a channel protein lacking apparent transport function expressed in brain.
Volume:	7

Pages:	14

•

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Search results 1301 to 1349 out of 1349 for Aqp1

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