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Search results 201 to 298 out of 298 for Mta1

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Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 627  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 686  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 730  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 698  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 702  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 715  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
Publication
First Author: Oehring SC
Year: 2012
Journal: Genome Biol
Title: Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum.
Volume: 13
Issue: 11
Pages: R108
Publication
First Author: Pakala SB
Year: 2017
Journal: J Biol Chem
Title: Regulation of NF-κB circuitry by a component of the nucleosome remodeling and deacetylase complex controls inflammatory response homeostasis.
Volume: 292
Issue: 11
Pages: 4764
Interaction Experiment
Description: Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3.
Interaction Experiment
Description: MTA1 coregulation of transglutaminase 2 expression and function during inflammatory response.
Publication
First Author: Zhou J
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expression.
Volume: 99
Issue: 21
Pages: 13693-8
Publication
First Author: Mishra SK
Year: 2004
Journal: Oncogene
Title: Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-gamma2, an estrogen-responsive kinase.
Volume: 23
Issue: 25
Pages: 4422-9
Publication
First Author: Ghanta KS
Year: 2011
Journal: J Biol Chem
Title: MTA1 coregulation of transglutaminase 2 expression and function during inflammatory response.
Volume: 286
Issue: 9
Pages: 7132-8
Protein
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 55  
Fragment?: true
Publication
First Author: Solari F
Year: 1999
Journal: Development
Title: The Caenorhabditis elegans genes egl-27 and egr-1 are similar to MTA1, a member of a chromatin regulatory complex, and are redundantly required for embryonic patterning.
Volume: 126
Issue: 11
Pages: 2483-94
Protein Domain
Type: Domain
Description: The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown function. It is found in the MTA1 protein that is part of the NuRD complex []. The domain is usually found to the N terminus of a myb-like DNA binding domain and a GATA binding domain. ELM2, in some instances, is also found associated with the ARID DNA binding domain . This suggests that ELM2 may also be involved in DNA binding, or perhaps is a protein-protein interaction domain.
Publication
First Author: Yaguchi M
Year: 2005
Journal: Biochim Biophys Acta
Title: Identification and characterization of the variants of metastasis-associated protein 1 generated following alternative splicing.
Volume: 1732
Issue: 1-3
Pages: 8-14
Publication  
First Author: Millard CJ
Year: 2016
Journal: Elife
Title: The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Volume: 5
Pages: e13941
Protein Domain
Type: Domain
Description: The R1 domain is found in the MTA1 protein and its homologues. The domain is composed of 4 alpha helices. It has been shown to bind to the RBBP4 protein []. The MTA proteins contain a second partial copy of this domain called R2. The R2 domain is matched by this model for some proteins.
Publication
First Author: Toh Y
Year: 2009
Journal: Clin Exp Metastasis
Title: The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications.
Volume: 26
Issue: 3
Pages: 215-27
Publication
First Author: Zhang Y
Year: 1999
Journal: Genes Dev
Title: Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.
Volume: 13
Issue: 15
Pages: 1924-35
Protein
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 97  
Fragment?: true
Protein Domain
Type: Family
Description: MTA (metastasis-associated) proteins, including MTA1-3, are transcriptional co-repressors that function in histone deacetylation and are involved in the NuRD complex. Nevertheless, MTA1 and MTA2 have been shown to deacetylate non-histone proteins, such as p53. The expression of MTA proteins have been linked to human cancers [].Mesoderm induction early response proteins (MIER1-3) are ELM2-SANT domain-containing proteins. MIER1 functions as a transcriptional repressor through its ability to recruit HDAC1/2 activity[]. The function of MIER2 and MIER3 is not clear [].
Protein Domain
Type: Family
Description: Metastasis-associated protein MTA2 is a component of the nucleosome-remodeling and histone-deacetylase multiprotein complex (NuRD) []. It is a member of the MTA family.MTA (metastasis-associated) family members, including MTA1-3, are transcriptional co-repressors that function in histone deacetylation and are involved in the NuRD complex. Nevertheless, MTA1 and MTA2 have been shown to deacetylate non-histone proteins, such as p53. The expression of the MTA family members have been linked to human cancers [].
Publication
First Author: Chen WY
Year: 2005
Journal: Cell
Title: Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses.
Volume: 123
Issue: 3
Pages: 437-48
Publication
First Author: Zhang W
Year: 2010
Journal: Oncogene
Title: A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1.
Volume: 29
Issue: 17
Pages: 2467-76
Publication
First Author: Van Rechem C
Year: 2009
Journal: J Biol Chem
Title: Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1).
Volume: 284
Issue: 31
Pages: 20927-35
Publication
First Author: Pinte S
Year: 2004
Journal: J Biol Chem
Title: The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties.
Volume: 279
Issue: 37
Pages: 38313-24
Publication
First Author: Van Rechem C
Year: 2010
Journal: Mol Cell Biol
Title: Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells.
Volume: 30
Issue: 16
Pages: 4045-59
Protein Domain
Type: Family
Description: Hypermethylated in cancer 1 (HIC1) is a transcriptional repressor that modulates P53-dependent and E2F1-dependent cell growth control and is epigenetically inactivated in various human cancers []. It recognises and binds to the consensus sequence '5-[CG]NG[CG]GGGCA[CA]CC-3' []. It is a direct transcriptional repressor of ephrin-A1 and CXCR7, which are implicated in the pathogenesis of different cancers [, ]. HIC1 is also involved in down-regulation of SIRT1 and thereby is involved in regulation of p53/TP53-dependent apoptotic DNA-damage responses []. HIC1 interacts with several different corepressors such as CTBP1, CTBP2 and MTA1 (a subunit of the NuRD complex) [].
Publication
First Author: Dhar S
Year: 2017
Journal: FEBS Lett
Title: MTA1-activated Epi-microRNA-22 regulates E-cadherin and prostate cancer invasiveness.
Volume: 591
Issue: 6
Pages: 924-933
Publication
First Author: Korfanty J
Year: 2018
Journal: Reproduction
Title: SPEN protein expression and interactions with chromatin in mouse testicular cells.
Volume: 156
Issue: 3
Pages: 195-206
Protein
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
Publication
First Author: Bagheri-Yarmand R
Year: 2007
Journal: Cancer Res
Title: Metastasis-associated protein 1 transgenic mice: a new model of spontaneous B-cell lymphomas.
Volume: 67
Issue: 15
Pages: 7062-7
Publication
First Author: Liang J
Year: 2008
Journal: Nat Cell Biol
Title: Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.
Volume: 10
Issue: 6
Pages: 731-9
Publication
First Author: Li DQ
Year: 2012
Journal: Cancer Res
Title: Metastasis-associated protein 1/nucleosome remodeling and histone deacetylase complex in cancer.
Volume: 72
Issue: 2
Pages: 387-94
Protein
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: true
Publication
First Author: Cuello-Carrión FD
Year: 2013
Journal: Cell Stress Chaperones
Title: In MMTV-Her-2/neu transgenic mammary tumors the absence of caveolin-1-/- alters PTEN and NHERF1 but not β-catenin expression.
Volume: 18
Issue: 5
Pages: 559-67
Publication
First Author: Bagheri-Yarmand R
Year: 2004
Journal: Development
Title: Metastasis-associated protein 1 deregulation causes inappropriate mammary gland development and tumorigenesis.
Volume: 131
Issue: 14
Pages: 3469-79
Protein
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: false
Publication
First Author: Derwish R
Year: 2017
Journal: PLoS One
Title: Differential HDAC1 and 2 Recruitment by Members of the MIER Family.
Volume: 12
Issue: 1
Pages: e0169338
Protein
Organism: Mus musculus/domesticus
Length: 668  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 668  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 521  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 513  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 580  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 514  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 513  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 514  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 522  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 586  
Fragment?: false
Publication
First Author: Ding Z
Year: 2003
Journal: Mol Cell Biol
Title: Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain.
Volume: 23
Issue: 1
Pages: 250-8
Protein
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 511  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 511  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: true
Publication
First Author: Zhang H
Year: 2006
Journal: Clin Cancer Res
Title: Metastasis tumor antigen family proteins during breast cancer progression and metastasis in a reliable mouse model for human breast cancer.
Volume: 12
Issue: 5
Pages: 1479-86
Protein
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 523  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 451  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 479  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 382  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1010  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1011  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1558  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1290  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1071  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1089  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1205  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1363  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 733  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 714  
Fragment?: false
Publication
First Author: Villén J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Large-scale phosphorylation analysis of mouse liver.
Volume: 104
Issue: 5
Pages: 1488-93
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112