Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
GLI1 (glioma-associated oncogene homologue 1) is a central effector of the Hedgehog (HH) pathway, a pathway that governs many developmental processes []. It is a member of the GLI family of transcription factors, which also includes GLI2 and GLI3 []. GLI1 is an obligatory activator, whereas GLI2 and GLI3 carry activator and repressor functions []. GLI1 is amplified in a subset of human tumours []. It contains five repeats of a zinc finger DNA-binding motif and binds DNA in a sequence-specific fashion [, ]. |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
142
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1111
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
980
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
93
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Lo HW |
Year: |
2009 |
Journal: |
Cancer Res |
Title: |
A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion. |
Volume: |
69 |
Issue: |
17 |
Pages: |
6790-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
93
|
Fragment?: |
true |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5447303 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-01-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1742720 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:5447313 |
Age: |
embryonic day 12.0 |
Image: |
1A gli1 |
|
Specimen Label: |
1A gli1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5447303 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-01-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3262820 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:5447313 |
Age: |
embryonic day 12.0 |
Image: |
1A gli1 |
Note: |
Expression in posterior mesenchyme. |
Specimen Label: |
1A gli1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pavletich NP |
Year: |
1993 |
Journal: |
Science |
Title: |
Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers. |
Volume: |
261 |
Issue: |
5129 |
Pages: |
1701-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kinzler KW |
Year: |
1990 |
Journal: |
Mol Cell Biol |
Title: |
The GLI gene encodes a nuclear protein which binds specific sequences in the human genome. |
Volume: |
10 |
Issue: |
2 |
Pages: |
634-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang J |
Year: |
2008 |
Journal: |
Dev Cell |
Title: |
Hedgehog signaling in development and cancer. |
Volume: |
15 |
Issue: |
6 |
Pages: |
801-12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689517 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 10.5 |
Image: |
1D Gli1 Control |
Note: |
Expression in rostral ventral neuroepithelium |
Specimen Label: |
1D Gli1 Control |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689517 |
|
Stage: |
TS17 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 10.5 |
Image: |
1D Gli1 Gas1-/- |
Note: |
Expression in rostral ventral neuroepithelium completely lost. |
Specimen Label: |
1D Gli1 Gas1-/- |
Detected: |
false |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3264521 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:5446473 |
Age: |
embryonic day 13.5 |
Image: |
2 Gli1 13.5 spdh/spdh |
Note: |
Expression is delayed compared with wild type. Continuous expression through phalangeal anlagen, including future joint space, with the exception of the distal interphalangeal joint. |
Specimen Label: |
2 Gli1 13.5 spdh/spdh |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5810995 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640617 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:5823625 |
Age: |
embryonic day 10.5 |
Image: |
1C - Gli1 |
Note: |
This gene exhibits category 1 expression: staining is observed in the posterior/posterior-distal limb bud. |
Specimen Label: |
1C - Gli1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7576845 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640616 |
Pattern: |
Not Specified |
Stage: |
TS16 |
Assay Id: |
MGI:7576873 |
Age: |
embryonic day 10.0 |
Image: |
S3B Gli1 E10.0 delta/deltac |
Note: |
No significant alteration in spatial distribution of expression compared to control. |
Specimen Label: |
S3B Gli1 E10.0 delta/deltac |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7576845 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7576873 |
Age: |
embryonic day 10.5 |
Image: |
S3B Gli1 E10.5 WT |
|
Specimen Label: |
S3B Gli1 E10.5 WT |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1745721 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:5446509 |
Age: |
embryonic day 13.5 |
Image: |
5 Gli1 13.5 spdh/spdh |
Note: |
Expression surrounds entire metacarpophalangeal anlage, with exception only in interspace between middle and distal phalanges. |
Specimen Label: |
5 Gli1 13.5 spdh/spdh |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1742821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5446509 |
Age: |
embryonic day 13.5 |
Image: |
5 Gli1 13.5 wt |
|
Specimen Label: |
5 Gli1 13.5 wt |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1742822 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:5446509 |
Age: |
embryonic day 14.5 |
Image: |
5 Gli1 14.5 wt |
|
Specimen Label: |
5 Gli1 14.5 wt |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1742822 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:5446509 |
Age: |
embryonic day 14.5 |
Image: |
5 Gli1 14.5 spdh/spdh |
|
Specimen Label: |
5 Gli1 14.5 spdh/spdh |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614413 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 8.5 |
Image: |
1A Gli1 Control |
Note: |
Expression in prechordal plate (PrCP) and overlying rostral diencephalon ventral midline (RDVM). |
Specimen Label: |
1A Gli1 Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614413 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 8.5 |
Image: |
1A Gli1 Gas1-/- |
Note: |
No difference in expression compared to control |
Specimen Label: |
1A Gli1 Gas1-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614413 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 8.5 |
Image: |
1B Gli1 Control |
Note: |
Expression in prechordal plate (PrCP) and overlying rostral diencephalon ventral midline (RDVM). |
Specimen Label: |
1B Gli1 Control |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614413 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 8.5 |
Image: |
1B Gli1 Gas1-/- |
Note: |
No difference in expression compared to control. |
Specimen Label: |
1B Gli1 Gas1-/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1664015 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 9.5 |
Image: |
1C Gli1 Gas1-/- |
Note: |
Expression in rostral ventral neuroepithelium decreased compared to controls. |
Specimen Label: |
1C Gli1 Gas1-/- |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1664015 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 9.5 |
Image: |
1C Gli1 Control |
Note: |
Expression in rostral ventral neuroepithelium. |
Specimen Label: |
1C Gli1 Control |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3263921 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:5446473 |
Age: |
embryonic day 13.5 |
Image: |
2 Gli1 13.5 wt |
Note: |
Strong expression in cartilaginous anlagen. No expression in future joint space. |
Specimen Label: |
2 Gli1 13.5 wt |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3262920 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:5446473 |
Age: |
embryonic day 12.5 |
Image: |
2 Gli1 12.5 wt |
Note: |
Strong expression in cartilaginous anlagen. |
Specimen Label: |
2 Gli1 12.5 wt |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3262920 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:5446473 |
Age: |
embryonic day 12.5 |
Image: |
2 Gli1 12.5 spdh/spdh |
Note: |
Expression is delayed compared with wild type. Drastically reduced expression in digit primordia. |
Specimen Label: |
2 Gli1 12.5 spdh/spdh |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1724819 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5446473 |
Age: |
embryonic day 11.5 |
Image: |
2 Gli1 11.5 wt |
Note: |
Strong expression in cartilaginous anlagen. No expression in developing joint/interzone region. |
Specimen Label: |
2 Gli1 11.5 wt |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5446224 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-12-19 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1724819 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5446473 |
Age: |
embryonic day 11.5 |
Image: |
2 Gli1 11.5 spdh/spdh |
Note: |
Expression is delayed compared with wild type. Drastically reduced expression in digit primordia. |
Specimen Label: |
2 Gli1 11.5 spdh/spdh |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6191646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752526 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6191649 |
Age: |
embryonic day 18.5 |
Image: |
9A Gli1 WT |
Note: |
Authors report no differences in expression levels between wild-type and null animals. |
Specimen Label: |
9A Gli1 WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6191646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752526 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6191649 |
Age: |
embryonic day 18.5 |
Image: |
9A Gli1 NULL |
Note: |
Authors report no differences in expression levels between wild-type and null animals. |
Specimen Label: |
9A Gli1 NULL |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7576845 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640616 |
Pattern: |
Not Specified |
Stage: |
TS16 |
Assay Id: |
MGI:7576873 |
Age: |
embryonic day 10.0 |
Image: |
S3B Gli1 E10.0 WT |
|
Specimen Label: |
S3B Gli1 E10.0 WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7576845 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7576873 |
Age: |
embryonic day 10.5 |
Image: |
S3B Gli1 E10.5 delta/deltac |
Note: |
No significant alteration in spatial distribution of expression compared to control. |
Specimen Label: |
S3B Gli1 E10.5 delta/deltac |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5810995 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640617 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:5823625 |
Age: |
embryonic day 10.5 |
Image: |
S1A - Gli1 - E10.5 |
Note: |
This gene exhibits category 1 expression: staining is observed in the posterior/posterior-distal limb bud. |
Specimen Label: |
S1A - Gli1 - E10.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5810995 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640619 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5823625 |
Age: |
embryonic day 11.5 |
Image: |
S1A - Gli1 - E11.5 |
Note: |
This gene exhibits category 1 expression: staining is observed in the posterior/posterior-distal limb bud. |
Specimen Label: |
S1A - Gli1 - E11.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614413 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 8.5 |
Image: |
S1A 8-9 somites Gli1 Gas1-/- |
Note: |
No difference in expression compared to control. |
Specimen Label: |
S1A 8-9 somites Gli1 Gas1-/- |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614413 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 8.5 |
Image: |
S1A 10-11 somites Gli1 Control |
Note: |
Expression in prechordal plate (PrCP) and overlying rostral diencephalon ventral midline (RDVM). Co-expression with Shh. |
Specimen Label: |
S1A 10-11 somites Gli1 Control |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388586 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1614413 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:6866989 |
Age: |
embryonic day 8.5 |
Image: |
S1A 10-11 somites Gli1 Gas1-/- |
Note: |
No difference in expression compared to control. |
Specimen Label: |
S1A 10-11 somites Gli1 Gas1-/- |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hui CC |
Year: |
2011 |
Journal: |
Annu Rev Cell Dev Biol |
Title: |
Gli proteins in development and disease. |
Volume: |
27 |
|
Pages: |
513-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen V |
Year: |
2005 |
Journal: |
Development |
Title: |
Cooperative requirement of the Gli proteins in neurogenesis. |
Volume: |
132 |
Issue: |
14 |
Pages: |
3267-79 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1277646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3594416 |
Pattern: |
Not Specified |
Stage: |
TS16 |
Assay Id: |
MGI:7572390 |
Age: |
embryonic day 10.0 |
|
Note: |
Expression enriched in notochord, limb buds and head region. |
Specimen Label: |
3E Gli1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1277646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3185816 |
Pattern: |
Not Specified |
Stage: |
TS16 |
Assay Id: |
MGI:7572390 |
Age: |
embryonic day 10.0 |
|
Note: |
Expression enriched in notochord, limb buds and head region. |
Specimen Label: |
3E Gli1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1277646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-01-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619116 |
Pattern: |
Not Specified |
Stage: |
TS16 |
Assay Id: |
MGI:7572390 |
Age: |
embryonic day 10.0 |
|
Note: |
Expression enriched in notochord, limb buds and head region. |
Specimen Label: |
3E Gli1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu CZ |
Year: |
1998 |
Journal: |
Gene |
Title: |
Characterization of the promoter region and genomic organization of GLI, a member of the Sonic hedgehog-Patched signaling pathway. |
Volume: |
209 |
Issue: |
1-2 |
Pages: |
1-11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1320893 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-04 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1792121 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:1320902 |
Age: |
embryonic day 13.5 |
Image: |
8F |
Note: |
Gli1 was significantly upregulated. |
Specimen Label: |
8F |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1320893 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-04 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1794221 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:1320902 |
Age: |
embryonic day 13.5 |
Image: |
8F |
Note: |
Gli1 was significantly upregulated. |
Specimen Label: |
8F |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kugler MC |
Year: |
2019 |
Journal: |
Exp Lung Res |
Title: |
The Hedgehog target Gli1 is not required for bleomycin-induced lung fibrosis. |
Volume: |
45 |
Issue: |
1-2 |
Pages: |
22-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Merchant A |
Year: |
2010 |
Journal: |
Blood |
Title: |
Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors. |
Volume: |
115 |
Issue: |
12 |
Pages: |
2391-6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1277646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-11-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3594417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7380682 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
S1F Gli1 WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1277646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-11-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3594417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7380682 |
Age: |
embryonic day 10.5 |
|
Note: |
Normal expression pattern compared to wild type. |
Specimen Label: |
S1F Gli1 bromi |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kimura H |
Year: |
2005 |
Journal: |
Oncogene |
Title: |
Gli1 is important for medulloblastoma formation in Ptc1+/- mice. |
Volume: |
24 |
Issue: |
25 |
Pages: |
4026-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Walterhouse D |
Year: |
1993 |
Journal: |
Dev Dyn |
Title: |
gli, a zinc finger transcription factor and oncogene, is expressed during normal mouse development. |
Volume: |
196 |
Issue: |
2 |
Pages: |
91-102 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kitaura Y |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Gli1 haploinsufficiency leads to decreased bone mass with an uncoupling of bone metabolism in adult mice. |
Volume: |
9 |
Issue: |
10 |
Pages: |
e109597 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fiaschi M |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
Targeted expression of GLI1 in the mammary gland disrupts pregnancy-induced maturation and causes lactation failure. |
Volume: |
282 |
Issue: |
49 |
Pages: |
36090-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fiaschi M |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Targeted expression of GLI1 in the salivary glands results in an altered differentiation program and hyperplasia. |
Volume: |
179 |
Issue: |
5 |
Pages: |
2569-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mathew E |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
The transcription factor GLI1 modulates the inflammatory response during pancreatic tissue remodeling. |
Volume: |
289 |
Issue: |
40 |
Pages: |
27727-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lees CW |
Year: |
2008 |
Journal: |
PLoS Med |
Title: |
Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways. |
Volume: |
5 |
Issue: |
12 |
Pages: |
e239 |
|
•
•
•
•
•
|
Publication |
First Author: |
Samanta J |
Year: |
2015 |
Journal: |
Nature |
Title: |
Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination. |
Volume: |
526 |
Issue: |
7573 |
Pages: |
448-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kroft TL |
Year: |
2001 |
Journal: |
Biol Reprod |
Title: |
GLI1 localization in the germinal epithelial cells alternates between cytoplasm and nucleus: upregulation in transgenic mice blocks spermatogenesis in pachytene. |
Volume: |
65 |
Issue: |
6 |
Pages: |
1663-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zotter B |
Year: |
2022 |
Journal: |
J Neurosci |
Title: |
Gli1 Regulates the Postnatal Acquisition of Peripheral Nerve Architecture. |
Volume: |
42 |
Issue: |
2 |
Pages: |
183-201 |
|
•
•
•
•
•
|
Publication |
First Author: |
El-Zaatari M |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. |
Volume: |
8 |
Issue: |
3 |
Pages: |
e58935 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morita K |
Year: |
2006 |
Journal: |
J Dermatol Sci |
Title: |
HAN11 binds mDia1 and controls GLI1 transcriptional activity. |
Volume: |
44 |
Issue: |
1 |
Pages: |
11-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mills LD |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression. |
Volume: |
289 |
Issue: |
23 |
Pages: |
16516-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi Y |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Gli1 identifies osteogenic progenitors for bone formation and fracture repair. |
Volume: |
8 |
Issue: |
1 |
Pages: |
2043 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mirza AN |
Year: |
2019 |
Journal: |
Cell |
Title: |
LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription. |
Volume: |
176 |
Issue: |
1-2 |
Pages: |
198-212.e15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bai CB |
Year: |
2001 |
Journal: |
Development |
Title: |
Gli1 can rescue the in vivo function of Gli2. |
Volume: |
128 |
Issue: |
24 |
Pages: |
5161-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
He P |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
Deficiency of patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice. |
Volume: |
23 |
Issue: |
24 |
Pages: |
6512-27 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1277646 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1741220 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:1327344 |
Age: |
embryonic day 12.5 |
Image: |
12.5 p.c. fore limb |
Note: |
Gli1 is restricted to the condensing mesenchyme. |
Specimen Label: |
12.5 p.c. fore limb |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
FOXS1 is regulated by GLI1 and miR-125a-5p and promotes cell proliferation and EMT in gastric cancer. |
Volume: |
9 |
Issue: |
1 |
Pages: |
5281 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173582 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190405 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Gli1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173582 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190405 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Gli1 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173582 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190405 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Gli1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173582 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190405 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Gli1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173582 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190405 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Gli1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173582 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190405 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Gli1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6173582 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190405 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Gli1 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coni S |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma. |
Volume: |
7 |
|
Pages: |
44079 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peng J |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Gli1 marks a sentinel muscle stem cell population for muscle regeneration. |
Volume: |
14 |
Issue: |
1 |
Pages: |
6993 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dai P |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. |
Volume: |
274 |
Issue: |
12 |
Pages: |
8143-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee J |
Year: |
1997 |
Journal: |
Development |
Title: |
Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. |
Volume: |
124 |
Issue: |
13 |
Pages: |
2537-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Di Marcotullio L |
Year: |
2006 |
Journal: |
Nat Cell Biol |
Title: |
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination. |
Volume: |
8 |
Issue: |
12 |
Pages: |
1415-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barnfield PC |
Year: |
2005 |
Journal: |
Differentiation |
Title: |
Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms. |
Volume: |
73 |
Issue: |
8 |
Pages: |
397-405 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1320893 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1735519 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:1320902 |
Age: |
embryonic day 11.5 |
Image: |
1D |
Note: |
The expression of Gli1 was similar to Ptc expression. |
Specimen Label: |
1D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1320893 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1735919 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:1320902 |
Age: |
embryonic day 11.5 |
Image: |
1D |
Note: |
The expression of Gli1 was similar to Ptc expression. |
Specimen Label: |
1D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1320893 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-04 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1794321 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:1320902 |
Age: |
embryonic day 13.5 |
Image: |
8H |
Note: |
Gli1 was slightly weaker in the epithelial component. |
Specimen Label: |
8H |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1320893 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-01-04 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1792221 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:1320902 |
Age: |
embryonic day 13.5 |
Image: |
8H |
Note: |
Gli1 was slightly weaker in the epithelial component. |
Specimen Label: |
8H |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
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