Type |
Details |
Score |
Genotype |
Symbol: |
Ccdc59/Ccdc59 |
Background: |
C57BL/6NJ-Ccdc59/J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Trpm3/Trpm3 |
Background: |
involves: C57BL/6J * CBA |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Trpm3/Trpm3 |
Background: |
involves: 129S5/SvEvBrd * C57BL/6J * CBA |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pkm/Pkm |
Background: |
C57BL/6N-Pkm/Mmmh |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
905
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
905
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
667
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1024
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1769
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
666
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
667
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
900
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
690
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
676
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
564
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
905
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1761
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
905
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
905
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
580
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
666
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
620
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
666
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gunawardane RN |
Year: |
2000 |
Journal: |
J Cell Biol |
Title: |
Characterization and reconstitution of Drosophila gamma-tubulin ring complex subunits. |
Volume: |
151 |
Issue: |
7 |
Pages: |
1513-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou L |
Year: |
2017 |
Journal: |
FASEB J |
Title: |
Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development. |
Volume: |
31 |
Issue: |
1 |
Pages: |
132-147 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Parmacek MS |
Year: |
1989 |
Journal: |
Nucleic Acids Res |
Title: |
Structure, expression and regulation of the murine 4F2 heavy chain. |
Volume: |
17 |
Issue: |
5 |
Pages: |
1915-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alkuraya FS |
Year: |
2011 |
Journal: |
Am J Hum Genet |
Title: |
Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected]. |
Volume: |
88 |
Issue: |
5 |
Pages: |
536-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Z |
Year: |
2012 |
Journal: |
Transplantation |
Title: |
Deletion of CD98 heavy chain in T cells results in cardiac allograft acceptance by increasing regulatory T cells. |
Volume: |
93 |
Issue: |
11 |
Pages: |
1116-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cybulska-Klosowicz A |
Year: |
2004 |
Journal: |
Neurobiol Dis |
Title: |
Impaired learning-dependent cortical plasticity in Huntington's disease transgenic mice. |
Volume: |
17 |
Issue: |
3 |
Pages: |
427-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen HT |
Year: |
2011 |
Journal: |
J Clin Invest |
Title: |
CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice. |
Volume: |
121 |
Issue: |
5 |
Pages: |
1733-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cantor J |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity. |
Volume: |
187 |
Issue: |
2 |
Pages: |
851-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsumura H |
Year: |
2003 |
Journal: |
Biochem Biophys Res Commun |
Title: |
The targeted disruption of the CD98 gene results in embryonic lethality. |
Volume: |
308 |
Issue: |
4 |
Pages: |
847-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bajaj J |
Year: |
2016 |
Journal: |
Cancer Cell |
Title: |
CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia. |
Volume: |
30 |
Issue: |
5 |
Pages: |
792-805 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tissot FS |
Year: |
2018 |
Journal: |
J Invest Dermatol |
Title: |
Dermal Fibroblast SLC3A2 Deficiency Leads to Premature Aging and Loss of Epithelial Homeostasis. |
Volume: |
138 |
Issue: |
12 |
Pages: |
2511-2521 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boulter E |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway. |
Volume: |
9 |
Issue: |
1 |
Pages: |
4862 |
|
•
•
•
•
•
|
Publication |
First Author: |
Breuer M |
Year: |
2010 |
Journal: |
J Cell Biol |
Title: |
HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells. |
Volume: |
191 |
Issue: |
7 |
Pages: |
1251-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boulter E |
Year: |
2013 |
Journal: |
J Exp Med |
Title: |
CD98hc (SLC3A2) regulation of skin homeostasis wanes with age. |
Volume: |
210 |
Issue: |
1 |
Pages: |
173-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liao Z |
Year: |
2016 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Endothelial Cells Require CD98 for Efficient Angiogenesis-Brief Report. |
Volume: |
36 |
Issue: |
11 |
Pages: |
2163-2166 |
|
•
•
•
•
•
|
Publication |
First Author: |
Charania MA |
Year: |
2012 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Intestinal epithelial CD98 synthesis specifically modulates expression of colonic microRNAs during colitis. |
Volume: |
302 |
Issue: |
11 |
Pages: |
G1282-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhuyan ZA |
Year: |
2014 |
Journal: |
Biochem Biophys Res Commun |
Title: |
CD98hc regulates the development of experimental colitis by controlling effector and regulatory CD4(+) T cells. |
Volume: |
444 |
Issue: |
4 |
Pages: |
628-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quackenbush E |
Year: |
1987 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth. |
Volume: |
84 |
Issue: |
18 |
Pages: |
6526-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bröer S |
Year: |
1995 |
Journal: |
Biochem J |
Title: |
The 4F2hc surface antigen is necessary for expression of system L-like neutral amino acid-transport activity in C6-BU-1 rat glioma cells: evidence from expression studies in Xenopus laevis oocytes. |
Volume: |
312 ( Pt 3) |
|
Pages: |
863-70 |
|
•
•
•
•
•
|