Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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|
|
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•
•
•
•
•
|
Allele |
Name: |
cytoskeleton associated protein 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Publication |
First Author: |
Reber SB |
Year: |
2013 |
Journal: |
Nat Cell Biol |
Title: |
XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules. |
Volume: |
15 |
Issue: |
9 |
Pages: |
1116-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Widlund PO |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region. |
Volume: |
108 |
Issue: |
7 |
Pages: |
2741-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Podolski M |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Stu2, the budding yeast XMAP215/Dis1 homolog, promotes assembly of yeast microtubules by increasing growth rate and decreasing catastrophe frequency. |
Volume: |
289 |
Issue: |
41 |
Pages: |
28087-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nabeshima K |
Year: |
1995 |
Journal: |
Genes Dev |
Title: |
p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites. |
Volume: |
9 |
Issue: |
13 |
Pages: |
1572-85 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
XMAP215 proteins, such as Alp14 and XMAP215 (also known as CKAP5), increase microtubules dynamic polymerization rates by recruiting soluble alpha/beta-tubulin via their conserved TOG domains to polymerizing microtubule plus ends [, , ]. The TOG domain contains HEAT repeats, forming a oblong paddle-like structure. CKAP5 plays a major role in organizing spindle poles and acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibres of the mitotic spindle by acting as inter-microtubule bridge [].Proteins in this family also includes the XMAP215 homologue, Stu2 from budding yeasts []and Alp14/Dis1 from fission yeasts []. |
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•
•
•
•
•
|
Publication |
First Author: |
Al-Bassam J |
Year: |
2011 |
Journal: |
Trends Cell Biol |
Title: |
Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP. |
Volume: |
21 |
Issue: |
10 |
Pages: |
604-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Al-Bassam J |
Year: |
2014 |
Journal: |
Methods Enzymol |
Title: |
Reconstituting dynamic microtubule polymerization regulation by TOG domain proteins. |
Volume: |
540 |
|
Pages: |
131-48 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2032
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2032
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1972
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1711
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2011
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
•
•
•
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