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Search results 1001 to 1100 out of 1150 for Ptf1a

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Type Details Score
Publication
First Author: Magenheim J
Year: 2011
Journal: Dev Biol
Title: Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium.
Volume: 359
Issue: 1
Pages: 26-36
Publication
First Author: Pan FC
Year: 2015
Journal: Development
Title: Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells.
Volume: 142
Issue: 21
Pages: 3637-48
Publication  
First Author: Kuzelova A
Year: 2023
Journal: Cells
Title: Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance.
Volume: 12
Issue: 7
Publication  
First Author: Dupacova N
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Meis homeobox genes control progenitor competence in the retina.
Volume: 118
Issue: 12
Publication
First Author: Medina CF
Year: 2009
Journal: Hum Mol Genet
Title: Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome.
Volume: 18
Issue: 5
Pages: 966-77
Publication
First Author: Nakatani T
Year: 2014
Journal: Dev Biol
Title: The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells.
Volume: 388
Issue: 1
Pages: 68-80
Publication
First Author: Sand FW
Year: 2011
Journal: Dev Biol
Title: Growth-limiting role of endothelial cells in endoderm development.
Volume: 352
Issue: 2
Pages: 267-77
Publication
First Author: Ait-Lounis A
Year: 2010
Journal: Diabetes
Title: The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression.
Volume: 59
Issue: 7
Pages: 1674-85
Publication
First Author: Westmoreland JJ
Year: 2012
Journal: Gastroenterology
Title: Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreas.
Volume: 142
Issue: 4
Pages: 999-1009.e6
Publication
First Author: Arnes L
Year: 2016
Journal: Genes Dev
Title: βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function.
Volume: 30
Issue: 5
Pages: 502-7
Publication
First Author: Afelik S
Year: 2015
Journal: Dev Biol
Title: Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development.
Volume: 399
Issue: 2
Pages: 204-17
Publication
First Author: Asayesh A
Year: 2006
Journal: Genes Dev
Title: Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice.
Volume: 20
Issue: 16
Pages: 2208-13
Publication
First Author: Rodríguez-Seguel E
Year: 2020
Journal: J Pathol
Title: Loss of GATA4 causes ectopic pancreas in the stomach.
Volume: 250
Issue: 4
Pages: 362-373
Publication
First Author: George NM
Year: 2012
Journal: Mol Cell Biol
Title: Hippo signaling regulates pancreas development through inactivation of Yap.
Volume: 32
Issue: 24
Pages: 5116-28
Publication  
First Author: Cerdá-Esteban N
Year: 2017
Journal: Nat Commun
Title: Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Volume: 8
Pages: 14127
Publication
First Author: Qiu F
Year: 2008
Journal: J Neurosci
Title: A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors.
Volume: 28
Issue: 13
Pages: 3392-403
Publication
First Author: Sugiyama T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.
Volume: 110
Issue: 31
Pages: 12691-6
Publication
First Author: Svensson P
Year: 2009
Journal: Mol Cell Biol
Title: MFng is dispensable for mouse pancreas development and function.
Volume: 29
Issue: 8
Pages: 2129-38
Publication
First Author: Poché RA
Year: 2007
Journal: J Neurosci
Title: Lim1 is essential for the correct laminar positioning of retinal horizontal cells.
Volume: 27
Issue: 51
Pages: 14099-107
Publication
First Author: Oliver-Krasinski JM
Year: 2009
Journal: J Clin Invest
Title: The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.
Volume: 119
Issue: 7
Pages: 1888-98
Publication  
First Author: Das G
Year: 2009
Journal: Neural Dev
Title: Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells.
Volume: 4
Pages: 15
Publication
First Author: Norgaard GA
Year: 2003
Journal: Dev Biol
Title: FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development.
Volume: 264
Issue: 2
Pages: 323-38
Publication
First Author: Liu ZR
Year: 2010
Journal: Brain Res Bull
Title: A refined map of early gene expression in the dorsal rhombomere 1 of mouse embryos.
Volume: 82
Issue: 1-2
Pages: 74-82
Publication
First Author: Seymour PA
Year: 2020
Journal: Dev Cell
Title: Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors.
Volume: 52
Issue: 6
Pages: 731-747.e8
Publication
First Author: Wu M
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype.
Volume: 62
Issue: 7
Pages: 1
Publication
First Author: Heymans C
Year: 2021
Journal: Sci Rep
Title: Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function.
Volume: 11
Issue: 1
Pages: 14519
Publication    
First Author: Ramirez M
Year: 2022
Journal: Elife
Title: Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions.
Volume: 11
Publication
First Author: Hwang I
Year: 2022
Journal: Mol Psychiatry
Title: Cerebellar dysfunction and schizophrenia-like behavior in Ebp1-deficient mice.
Volume: 27
Issue: 4
Pages: 2030-2041
Publication  
First Author: Zheng MH
Year: 2009
Journal: Mol Brain
Title: The transcription factor RBP-J is essential for retinal cell differentiation and lamination.
Volume: 2
Pages: 38
Publication
First Author: Hägglund AC
Year: 2013
Journal: PLoS One
Title: Canonical Wnt/β-catenin signalling is essential for optic cup formation.
Volume: 8
Issue: 12
Pages: e81158
Publication
First Author: Scavuzzo MA
Year: 2018
Journal: Cell Rep
Title: Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.
Volume: 25
Issue: 13
Pages: 3811-3827.e7
Publication
First Author: Hu J
Year: 2012
Journal: J Neurosci
Title: c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections.
Volume: 32
Issue: 16
Pages: 5362-73
Publication
First Author: Muñoz-Bravo JL
Year: 2016
Journal: PLoS One
Title: Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity.
Volume: 11
Issue: 10
Pages: e0164714
Publication  
First Author: Pujadas G
Year: 2016
Journal: Sci Rep
Title: Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas.
Volume: 6
Pages: 19223
Publication
First Author: Roome RB
Year: 2020
Journal: Cell Rep
Title: Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans.
Volume: 33
Issue: 8
Pages: 108425
Publication  
First Author: Norlin S
Year: 2018
Journal: Development
Title: The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival.
Volume: 145
Issue: 1
Publication
First Author: Prévot PP
Year: 2013
Journal: Gastroenterology
Title: Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6.
Volume: 145
Issue: 3
Pages: 668-78.e3
Publication
First Author: Farhy C
Year: 2013
Journal: PLoS One
Title: Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells.
Volume: 8
Issue: 9
Pages: e76489
Publication
First Author: Davis N
Year: 2011
Journal: Development
Title: Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium.
Volume: 138
Issue: 1
Pages: 127-38
Publication
First Author: Cobo I
Year: 2023
Journal: Nat Commun
Title: NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation.
Volume: 14
Issue: 1
Pages: 3761
Publication
First Author: Petzold KM
Year: 2013
Journal: Development
Title: Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas.
Volume: 140
Issue: 1
Pages: 126-35
Publication
First Author: Scavuzzo MA
Year: 2018
Journal: Nat Commun
Title: Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis.
Volume: 9
Issue: 1
Pages: 3356
Publication
First Author: Fujimura N
Year: 2018
Journal: Dev Biol
Title: Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation.
Volume: 433
Issue: 1
Pages: 47-60
Publication
First Author: Ikuta K
Year: 2019
Journal: Gut
Title: Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice.
Volume: 68
Issue: 5
Pages: 882-892
Publication      
First Author: Luo L
Year: 2020
Journal: Neuron
Title: Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.
Publication
First Author: Hald J
Year: 2012
Journal: Diabetologia
Title: Pancreatic islet and progenitor cell surface markers with cell sorting potential.
Volume: 55
Issue: 1
Pages: 154-65
Publication
First Author: Zhou Q
Year: 2007
Journal: Dev Cell
Title: A multipotent progenitor domain guides pancreatic organogenesis.
Volume: 13
Issue: 1
Pages: 103-14
Publication
First Author: Stevens JD
Year: 2008
Journal: Differentiation
Title: Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.
Volume: 76
Issue: 9
Pages: 1006-22
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Campos ML
Year: 2013
Journal: Biochem J
Title: ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours.
Volume: 451
Issue: 3
Pages: 395-405
Publication
First Author: Guo Z
Year: 2012
Journal: J Neurosci
Title: Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.
Volume: 32
Issue: 25
Pages: 8509-20
Interaction Experiment
Description: Ptf1a and RBP-J cooperate in activating Pdx1 gene expression through binding to Area III.
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
HT Experiment
Series Id: GSE26816
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Allele
Name: pancreas specific transcription factor, 1a; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194375
Age: embryonic day 12.5
Image: 3I
Note: Some Olig2-positive cells express Ptf1a (marker for GABAergic neuron progenitors).
Specimen Label: 3I
Detected: true
Specimen Num: 5
Allele
Name: atonal bHLH transcription factor 1; targeted mutation 2, Mikio Hoshino
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
GXD Expression  
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1758520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7580782
Age: embryonic day 12.5
Note: Reduced expression compared with the wild-type, specifically in the Ptf1a domain region.
Specimen Label: S2B"
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7580782
Age: embryonic day 10.5
Note: Reduced expression compared with the wild-type, specifically in the Ptf1a domain region.
Specimen Label: S2A"
Detected: true
Specimen Num: 12
GXD Expression
Probe: MGI:6194268
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194384
Age: embryonic day 12.5
Image: 3C
Note: Expression was detected in postmitotic GABAergic neurons. There was no overlap with Ptf1a expression.
Specimen Label: 3C
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6194268
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194386
Age: embryonic day 12.5
Image: 3C
Note: Expression was detected in postmitotic GABAergic neurons. There was no overlap with Ptf1a expression.
Specimen Label: 3C
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1725617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6695727
Age: embryonic day 10.5
Image: 5A Pdx-1 (lower)
Note: Expression coincident with Ptf1a throughout ventral pancreatic epithelium, except for first wave endocrine cells.
Specimen Label: 5A Pdx-1 (lower)
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6695727
Age: embryonic day 10.5
Image: 5A Pdx-1 (upper)
Note: Expression coincident with Ptf1a throughout dorsal pancreatic epithelium, except for first wave endocrine cells.
Specimen Label: 5A Pdx-1 (upper)
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6695356
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6695727
Age: embryonic day 11.5
Note: Expression still coincides with that of Ptf1a in almost all pancreatic epithelial cells.
Specimen Label: E11.5 +/+ not shown
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1715219
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7580782
Age: embryonic day 11.5
Note: Reduced expression compared with the wild-type, specifically in the Ptf1a domain region.
Specimen Label: 2I"
Detected: true
Specimen Num: 8
MP Term
HT Experiment
Series Id: E-GEOD-55831
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
GXD Expression  
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1758520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7580782
Age: embryonic day 12.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2B'
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:7580780
Assay Type: RNA in situ
Annotation Date: 2024-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7580782
Age: embryonic day 10.5
Note: Expressed in the ventricular zone in the dorsal spinal cord, with enrichment in regions lateral to the Ptf1a domain.
Specimen Label: S2A'
Detected: true
Specimen Num: 11