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Search results 301 to 364 out of 364 for Esx1

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Type Details Score
GXD Expression  
Probe: MGI:4427161
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824626
Age: embryonic day 14.5
Image: euxassay_016592_10
Specimen Label: euxassay_016592_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4427161
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824626
Age: embryonic day 14.5
Image: euxassay_016592_11
Specimen Label: euxassay_016592_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4427161
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824626
Age: embryonic day 14.5
Image: euxassay_016592_12
Specimen Label: euxassay_016592_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4427161
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824626
Age: embryonic day 14.5
Image: euxassay_016592_13
Specimen Label: euxassay_016592_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4427161
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824626
Age: embryonic day 14.5
Image: euxassay_016592_14
Specimen Label: euxassay_016592_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4427161
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824626
Age: embryonic day 14.5
Image: euxassay_016592_15
Specimen Label: euxassay_016592_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4427161
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824626
Age: embryonic day 14.5
Image: euxassay_016592_16
Specimen Label: euxassay_016592_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4427161
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824626
Age: embryonic day 14.5
Image: euxassay_016592_17
Specimen Label: euxassay_016592_17
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:3506067
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539139
Age: embryonic day 15.5
Image: GUDMAP:5335
Specimen Label: GUDMAP:5335
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506067
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539139
Age: embryonic day 15.5
Image: GUDMAP:5335
Specimen Label: GUDMAP:5335
Detected: true
Specimen Num: 1
Publication
First Author: Stanley SA
Year: 2007
Journal: J Immunol
Title: The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis.
Volume: 178
Issue: 5
Pages: 3143-52
Publication
First Author: Rantakari P
Year: 2008
Journal: Mol Endocrinol
Title: Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene.
Volume: 22
Issue: 3
Pages: 665-75
Publication
First Author: Nobs E
Year: 2024
Journal: mBio
Title: Cytosolic serpins act in a cytoprotective feedback loop that limits ESX-1-dependent death of Mycobacterium marinum-infected macrophages.
Volume: 15
Issue: 9
Pages: e0038424
Publication
First Author: Voss AK
Year: 2000
Journal: Development
Title: Mice lacking HSP90beta fail to develop a placental labyrinth.
Volume: 127
Issue: 1
Pages: 1-11
Publication
First Author: Mudgett JS
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis.
Volume: 97
Issue: 19
Pages: 10454-9
Publication
First Author: Pitman JL
Year: 1998
Journal: Dev Biol
Title: Normal reproductive and macrophage function in Pem homeobox gene-deficient mice.
Volume: 202
Issue: 2
Pages: 196-214
Publication
First Author: Simmons DG
Year: 2008
Journal: Development
Title: Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth.
Volume: 135
Issue: 12
Pages: 2083-91
Publication
First Author: Dupressoir A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene.
Volume: 106
Issue: 29
Pages: 12127-32
Publication
First Author: Dupressoir A
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast.
Volume: 108
Issue: 46
Pages: E1164-73
Publication
First Author: Biggs WH 3rd
Year: 2001
Journal: Mamm Genome
Title: Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse.
Volume: 12
Issue: 6
Pages: 416-25
Publication
First Author: Parr BA
Year: 2001
Journal: Dev Biol
Title: Wnt7b regulates placental development in mice.
Volume: 237
Issue: 2
Pages: 324-32
Publication
First Author: Kashif M
Year: 2011
Journal: Development
Title: p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth.
Volume: 138
Issue: 11
Pages: 2235-47
Publication
First Author: Lee EY
Year: 2009
Journal: Dev Biol
Title: E2F4 cooperates with pRB in the development of extra-embryonic tissues.
Volume: 332
Issue: 1
Pages: 104-15
Publication  
First Author: Sarkar AA
Year: 2016
Journal: Placenta
Title: Abnormal labyrinthine zone in the Hectd1-null placenta.
Volume: 38
Pages: 16-23
Publication
First Author: Pan Z
Year: 2008
Journal: Dev Dyn
Title: Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice.
Volume: 237
Issue: 2
Pages: 316-27
Publication  
First Author: Shafiei S
Year: 2021
Journal: Placenta
Title: Maternal Cripto is critical for proper development of the mouse placenta and the placental vasculature.
Volume: 107
Pages: 13-23
Publication  
First Author: Chou AM
Year: 2017
Journal: Sci Rep
Title: Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development.
Volume: 7
Pages: 40485
Publication
First Author: Solmonson A
Year: 2022
Journal: Nature
Title: Compartmentalized metabolism supports midgestation mammalian development.
Volume: 604
Issue: 7905
Pages: 349-353
Publication
First Author: Chen CY
Year: 2016
Journal: Hum Mol Genet
Title: Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis.
Volume: 25
Issue: 14
Pages: 2905-2922
Publication
First Author: Ouseph MM
Year: 2012
Journal: Dev Cell
Title: Atypical E2F repressors and activators coordinate placental development.
Volume: 22
Issue: 4
Pages: 849-62
Publication
First Author: Oda M
Year: 2006
Journal: Genes Dev
Title: DNA methylation regulates long-range gene silencing of an X-linked homeobox gene cluster in a lineage-specific manner.
Volume: 20
Issue: 24
Pages: 3382-94
Publication
First Author: Rhee C
Year: 2017
Journal: Dev Biol
Title: ARID3A is required for mammalian placenta development.
Volume: 422
Issue: 2
Pages: 83-91
Publication  
First Author: Fiorenzano A
Year: 2016
Journal: Nat Commun
Title: Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency.
Volume: 7
Pages: 12589
Publication
First Author: You L
Year: 2015
Journal: J Biol Chem
Title: The chromatin regulator Brpf1 regulates embryo development and cell proliferation.
Volume: 290
Issue: 18
Pages: 11349-64
Publication
First Author: Nishiyama A
Year: 2009
Journal: Cell Stem Cell
Title: Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors.
Volume: 5
Issue: 4
Pages: 420-33
Publication
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
Publication
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Yan YT
Year: 2000
Journal: Mol Cell Biol
Title: A novel PF/PN motif inhibits nuclear localization and DNA binding activity of the ESX1 homeoprotein.
Volume: 20
Issue: 2
Pages: 661-71
Publication
First Author: Fortune SM
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Mutually dependent secretion of proteins required for mycobacterial virulence.
Volume: 102
Issue: 30
Pages: 10676-81
Publication
First Author: Sala C
Year: 2018
Journal: PLoS Pathog
Title: EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis.
Volume: 14
Issue: 12
Pages: e1007491
Publication
First Author: van der Wel N
Year: 2007
Journal: Cell
Title: M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells.
Volume: 129
Issue: 7
Pages: 1287-98
Publication
First Author: Chen JM
Year: 2013
Journal: J Bacteriol
Title: Phenotypic profiling of Mycobacterium tuberculosis EspA point mutants reveals that blockage of ESAT-6 and CFP-10 secretion in vitro does not always correlate with attenuation of virulence.
Volume: 195
Issue: 24
Pages: 5421-30
Protein Domain
Type: Domain
Description: This entry represents a domain found in actinobacterial proteins, including EspA and EspE from Mycobacteria.The ESX-1 operon is present in a number of Mycobacteria strains []. In Mycobacterium tuberculosis (Mtb) the type VII ESX-1 secretion apparatus is used to translocate the key virulence factors EsxA (ESAT-6) and EsxB (CFP-10). In Mtb, the EspA protein is encoded by the unlinked espACD operon []. The EspA protein of Mycobacterium tuberculosis is essential for the type VII ESX-1 protein secretion apparatus []. EspA, ESAT-6, and CFP-10 are each critical for virulence of pathogenic mycobacteria and secretion of these three proteins, is mutually dependent [, ]. EspA undergoes Cys138-mediated homodimerization, although the process is not required for EspA or ESAT-6 secretion []. EspE is encoded by the ESX-1 operon []. In M. smegmatis it has been shown to colocalise with SaeC at, or near, the cell pole []. In M. smegmatis secretion of the heterodimer of EsxAB (ESAT-6/CFP-10) is dependent on the co-secretion of proteins encoded from both esx1 (eg., EspE) and non-esx1 genes (eg., EspA) [].
Publication
First Author: Zechner U
Year: 2002
Journal: Dev Dyn
Title: Proliferation and growth factor expression in abnormally enlarged placentas of mouse interspecific hybrids.
Volume: 224
Issue: 2
Pages: 125-34
Publication
First Author: Loschiavo M
Year: 2007
Journal: Mamm Genome
Title: Mapping and identification of candidate loci responsible for Peromyscus hybrid overgrowth.
Volume: 18
Issue: 1
Pages: 75-85
Publication
First Author: Singh U
Year: 2005
Journal: Dev Dyn
Title: Expression and functional analysis of genes deregulated in mouse placental overgrowth models: Car2 and Ncam1.
Volume: 234
Issue: 4
Pages: 1034-45