Type |
Details |
Score |
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
92
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
487
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
147
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
656
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
430
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
835
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
147
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
232
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
368
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
453
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
184
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
493
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
893
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Israel L |
Year: |
2017 |
Journal: |
Cell |
Title: |
Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity. |
Volume: |
168 |
Issue: |
5 |
Pages: |
789-800.e10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mansell A |
Year: |
2006 |
Journal: |
Nat Immunol |
Title: |
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. |
Volume: |
7 |
Issue: |
2 |
Pages: |
148-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Horng T |
Year: |
2002 |
Journal: |
Nature |
Title: |
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. |
Volume: |
420 |
Issue: |
6913 |
Pages: |
329-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andreakos E |
Year: |
2004 |
Journal: |
Blood |
Title: |
Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP. |
Volume: |
103 |
Issue: |
6 |
Pages: |
2229-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brown GT |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1β-rich microparticles. |
Volume: |
186 |
Issue: |
9 |
Pages: |
5489-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin SC |
Year: |
2010 |
Journal: |
Nature |
Title: |
Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. |
Volume: |
465 |
Issue: |
7300 |
Pages: |
885-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawagoe T |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2. |
Volume: |
9 |
Issue: |
6 |
Pages: |
684-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kenny EF |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3. |
Volume: |
183 |
Issue: |
6 |
Pages: |
3642-51 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
359
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
386
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
740
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
364
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
579
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
384
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
733
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
724
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
710
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
542
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
480
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
327
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
334
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
806
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
716
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
502
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
693
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
770
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
147
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
539
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
899
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Reynolds KE |
Year: |
2021 |
Journal: |
J Neuroimmunol |
Title: |
Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3. |
Volume: |
361 |
|
Pages: |
577745 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kinjyo I |
Year: |
2002 |
Journal: |
Immunity |
Title: |
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. |
Volume: |
17 |
Issue: |
5 |
Pages: |
583-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skokos D |
Year: |
2007 |
Journal: |
J Exp Med |
Title: |
CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS. |
Volume: |
204 |
Issue: |
7 |
Pages: |
1525-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maher K |
Year: |
2014 |
Journal: |
FEBS Lett |
Title: |
Decreased IL-10 expression in stefin B-deficient macrophages is regulated by the MAP kinase and STAT-3 signaling pathways. |
Volume: |
588 |
Issue: |
5 |
Pages: |
720-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Packiriswamy N |
Year: |
2012 |
Journal: |
Cell Immunol |
Title: |
Overlapping and distinct roles of GRK5 in TLR2-, and TLR3-induced inflammatory response in vivo. |
Volume: |
272 |
Issue: |
2 |
Pages: |
107-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hara H |
Year: |
2003 |
Journal: |
Immunity |
Title: |
The MAGUK family protein CARD11 is essential for lymphocyte activation. |
Volume: |
18 |
Issue: |
6 |
Pages: |
763-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quinn EM |
Year: |
2012 |
Journal: |
J Leukoc Biol |
Title: |
The emerging role of microRNA in regulation of endotoxin tolerance. |
Volume: |
91 |
Issue: |
5 |
Pages: |
721-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen L |
Year: |
2008 |
Journal: |
FEBS Lett |
Title: |
Protein phosphatase 4 negatively regulates LPS cascade by inhibiting ubiquitination of TRAF6. |
Volume: |
582 |
Issue: |
19 |
Pages: |
2843-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao W |
Year: |
2012 |
Journal: |
FEBS Lett |
Title: |
LY294002 inhibits TLR3/4-mediated IFN-β production via inhibition of IRF3 activation with a PI3K-independent mechanism. |
Volume: |
586 |
Issue: |
6 |
Pages: |
705-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qi J |
Year: |
2012 |
Journal: |
FEBS Lett |
Title: |
microRNA-210 negatively regulates LPS-induced production of proinflammatory cytokines by targeting NF-κB1 in murine macrophages. |
Volume: |
586 |
Issue: |
8 |
Pages: |
1201-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Straub T |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells. |
Volume: |
9 |
Issue: |
1 |
Pages: |
4117 |
|
•
•
•
•
•
|
Publication |
First Author: |
Greenhill CJ |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3. |
Volume: |
186 |
Issue: |
2 |
Pages: |
1199-208 |
|
•
•
•
•
•
|
Publication |
First Author: |
Layoun A |
Year: |
2012 |
Journal: |
Am J Pathol |
Title: |
Toll-like receptor signal adaptor protein MyD88 is required for sustained endotoxin-induced acute hypoferremic response in mice. |
Volume: |
180 |
Issue: |
6 |
Pages: |
2340-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kennedy CL |
Year: |
2014 |
Journal: |
Oncogene |
Title: |
Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis. |
Volume: |
33 |
Issue: |
19 |
Pages: |
2540-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ou XM |
Year: |
2003 |
Journal: |
J Neurosci |
Title: |
Freud-1: A neuronal calcium-regulated repressor of the 5-HT1A receptor gene. |
Volume: |
23 |
Issue: |
19 |
Pages: |
7415-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Basel-Vanagaite L |
Year: |
2006 |
Journal: |
J Med Genet |
Title: |
The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardation. |
Volume: |
43 |
Issue: |
3 |
Pages: |
203-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rogaeva A |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
Differential repression by freud-1/CC2D1A at a polymorphic site in the dopamine-D2 receptor gene. |
Volume: |
282 |
Issue: |
29 |
Pages: |
20897-905 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rogaeva A |
Year: |
2007 |
Journal: |
J Neurosci Res |
Title: |
The Freud-1/CC2D1A family: transcriptional regulators implicated in mental retardation. |
Volume: |
85 |
Issue: |
13 |
Pages: |
2833-8 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
inbred strain |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Vil1-cre)997Gum/? Tlr4/Tlr4 Tlr5/Tlr5 |
Background: |
involves: C57BL/6J * C57BL/6NTac * C57BL/10ScN * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
360
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
757
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
314
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
745
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
549
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
593
 |
Fragment?: |
false |
|
•
•
•
•
•
|