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Search results 101 to 185 out of 185 for Stub1

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Type Details Score
Publication
First Author: Dickey CA
Year: 2006
Journal: J Neurosci
Title: Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species.
Volume: 26
Issue: 26
Pages: 6985-96
Publication
First Author: Sane S
Year: 2018
Journal: Mol Oncol
Title: UBXN2A enhances CHIP-mediated proteasomal degradation of oncoprotein mortalin-2 in cancer cells.
Volume: 12
Issue: 10
Pages: 1753-1777
Publication
First Author: Ko HS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity.
Volume: 106
Issue: 8
Pages: 2897-902
Publication
First Author: Fukunishi Y
Year: 1999
Journal: FEBS Lett
Title: Prediction of human cDNA from its homologous mouse full-length cDNA and human shotgun database.
Volume: 464
Issue: 3
Pages: 129-32
Publication
First Author: Jiang J
Year: 2003
Journal: J Biol Chem
Title: Chaperone-dependent regulation of endothelial nitric-oxide synthase intracellular trafficking by the co-chaperone/ubiquitin ligase CHIP.
Volume: 278
Issue: 49
Pages: 49332-41
Publication
First Author: Li X
Year: 2008
Journal: J Cell Biol
Title: CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation.
Volume: 181
Issue: 6
Pages: 959-72
Publication
First Author: Su CH
Year: 2013
Journal: Arch Biochem Biophys
Title: Phosphorylation accelerates geldanamycin-induced Akt degradation.
Volume: 536
Issue: 1
Pages: 6-11
Publication
First Author: Yoo L
Year: 2018
Journal: J Biol Chem
Title: The ubiquitin E3 ligase CHIP promotes proteasomal degradation of the serine/threonine protein kinase PINK1 during staurosporine-induced cell death.
Volume: 293
Issue: 4
Pages: 1286-1297
Publication
First Author: Hu Z
Year: 2021
Journal: Aging (Albany NY)
Title: CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
Volume: 13
Issue: 1
Pages: 1458-1472
Publication
First Author: Choi YN
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Regulation of fragile X mental retardation 1 protein by C-terminus of Hsc70-interacting protein depends on its phosphorylation status.
Volume: 453
Issue: 1
Pages: 192-7
Publication
First Author: Dickey CA
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Akt and CHIP coregulate tau degradation through coordinated interactions.
Volume: 105
Issue: 9
Pages: 3622-7
Publication
First Author: Dai Q
Year: 2003
Journal: EMBO J
Title: CHIP activates HSF1 and confers protection against apoptosis and cellular stress.
Volume: 22
Issue: 20
Pages: 5446-58
Publication  
First Author: Nucifora FC Jr
Year: 2016
Journal: Nat Commun
Title: Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.
Volume: 7
Pages: 11792
Publication
First Author: Petrucelli L
Year: 2004
Journal: Hum Mol Genet
Title: CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation.
Volume: 13
Issue: 7
Pages: 703-14
Publication
First Author: Maruyama T
Year: 2010
Journal: EMBO J
Title: CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.
Volume: 29
Issue: 15
Pages: 2501-14
Publication
First Author: Cook C
Year: 2012
Journal: Hum Mol Genet
Title: Loss of HDAC6, a novel CHIP substrate, alleviates abnormal tau accumulation.
Volume: 21
Issue: 13
Pages: 2936-45
Publication
First Author: Jeong DH
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Ubiquitin-proteasome dependent regulation of Profilin2 (Pfn2) by a cellular inhibitor of apoptotic protein 1 (cIAP1).
Volume: 506
Issue: 3
Pages: 423-428
Publication
First Author: Hatakeyama S
Year: 2001
Journal: J Biol Chem
Title: U box proteins as a new family of ubiquitin-protein ligases.
Volume: 276
Issue: 35
Pages: 33111-20
Publication
First Author: Wang H
Year: 2013
Journal: J Immunol
Title: Enhanced endoplasmic reticulum entry of tumor antigen is crucial for cross-presentation induced by dendritic cell-targeted vaccination.
Volume: 191
Issue: 12
Pages: 6010-21
Publication
First Author: Arndt V
Year: 2010
Journal: Curr Biol
Title: Chaperone-assisted selective autophagy is essential for muscle maintenance.
Volume: 20
Issue: 2
Pages: 143-8
Publication  
First Author: Ko HR
Year: 2014
Journal: Cell Death Dis
Title: P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP.
Volume: 5
Pages: e1131
Publication
First Author: Teng Y
Year: 2015
Journal: Biochem Pharmacol
Title: UBXN2A regulates nicotinic receptor degradation by modulating the E3 ligase activity of CHIP.
Volume: 97
Issue: 4
Pages: 518-530
Publication
First Author: Reventun P
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: iNOS-Derived Nitric Oxide Induces Integrin-Linked Kinase Endocytic Lysosome-Mediated Degradation in the Vascular Endothelium.
Volume: 37
Issue: 7
Pages: 1272-1281
Publication  
First Author: Zheng H
Year: 2023
Journal: Development
Title: CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation.
Volume: 150
Issue: 10
Publication
First Author: Beilina A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Volume: 111
Issue: 7
Pages: 2626-31
Publication
First Author: Radovanac K
Year: 2013
Journal: EMBO J
Title: Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response.
Volume: 32
Issue: 10
Pages: 1409-24
Publication
First Author: Huang Z
Year: 2004
Journal: Mol Cell Biol
Title: Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination.
Volume: 24
Issue: 20
Pages: 8951-62
Publication
First Author: Yang M
Year: 2011
Journal: J Exp Med
Title: E3 ubiquitin ligase CHIP facilitates Toll-like receptor signaling by recruiting and polyubiquitinating Src and atypical PKC{zeta}.
Volume: 208
Issue: 10
Pages: 2099-112
Publication
First Author: Lim ST
Year: 2012
Journal: J Cell Biol
Title: Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.
Volume: 197
Issue: 7
Pages: 907-19
Publication      
First Author: Lexicon Genetics Inc
Year: 2005
Journal: MGI Direct Data Submission
Title: NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories
Publication      
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Del Prete D
Year: 2016
Journal: J Biol Chem
Title: Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.
Volume: 291
Issue: 33
Pages: 17209-27
Interaction Experiment
Description: Regulation of IL-4 Receptor Signaling by STUB1 in Lung Inflammation.
GXD Expression
Probe: MGI:7531826
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3288127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7532785
Age: postnatal day 1
Image: 5C left
Note: Proximity ligation assay indicated that Stub1 interacted with Dlx3 in undifferentiated dental mesenchymal cells.
Specimen Label: 5C left
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7531826
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3289727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7532785
Age: postnatal day 1
Image: 5C right
Note: Proximity ligation assay indicated that Stub1 interacted with Dlx3 in preodontoblasts of P1 molars.
Specimen Label: 5C right
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7531826
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3289428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7532785
Age: postnatal day 14
Image: 7Fa
Note: Proximity ligation assay indicated that Stub1 interacted with Dlx3 in undifferentiated dental mesenchymal cells.
Specimen Label: 7Fa
Detected: true
Specimen Num: 5
Interaction Experiment
Description: The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.
Allele
Name: transgene insertion 1, Gen Sobue
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Interaction Experiment
Description: A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common ? chain (CSF2RB) protein stability.
Publication
First Author: Koochaki SHJ
Year: 2022
Journal: J Biol Chem
Title: A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability.
Volume: 298
Issue: 10
Pages: 102484
Allele
Name: STIP1 homology and U-Box containing protein 1; targeted mutation 1, Cam Patterson
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Tg(CAG-STUB1)1Sobue/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-STUB1)1Sobue/Tg(CAG-STUB1)1Sobue
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
DO Term
Interaction Experiment
Description: Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.
Genotype
Symbol: Stub1/Stub1
Background: involves: 129S/SvEv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
DO Term
Genotype
Symbol: Tg(CAG-AR*97Q)7-8Sobue/? Tg(CAG-STUB1)1Sobue/Tg(CAG-STUB1)1Sobue
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-AR*97Q)7-8Sobue/? Tg(CAG-STUB1)1Sobue/?
Background: involves: C57BL/6 * C57BL/6J * DBA/2
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Fleskens V
Year: 2019
Journal: Cell Rep
Title: Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells.
Volume: 26
Issue: 13
Pages: 3600-3612.e6
Publication
First Author: Schiattarella GG
Year: 2021
Journal: Nat Commun
Title: Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction.
Volume: 12
Issue: 1
Pages: 1684
Publication
First Author: Shi Y
Year: 2020
Journal: J Biol Chem
Title: PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells.
Volume: 295
Issue: 40
Pages: 13798-13811
Publication  
First Author: Tang Z
Year: 2023
Journal: Free Radic Biol Med
Title: KDM1A-mediated upregulation of METTL3 ameliorates Alzheimer's disease via enhancing autophagic clearance of p-Tau through m6A-dependent regulation of STUB1.
Volume: 195
Pages: 343-358