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Search results 1 to 100 out of 188 for Sun1

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Hits by Strain

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Type Details Score
Gene
23353 | SUN1
Type: gene
Organism: human
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Gene
708786 | SUN1
Type: gene
Organism: macaque, rhesus
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Gene
100137098 | sun1
Type: gene
Organism: frog, western clawed
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Gene
360773 | Sun1
Type: gene
Organism: rat
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Gene
480806 | SUN1
Type: gene
Organism: dog, domestic
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Gene
472263 | SUN1
Type: gene
Organism: chimpanzee
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Gene
100847692 | SUN1
Type: gene
Organism: cattle
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Gene
416449 | SUN1
Type: gene
Organism: chicken
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Protein Domain
IPR018539 | SUN1
Type: Family
Description: SUN domain-containing protein 1 is a nuclear inner membrane protein and a component of the linker of the nucleoskeleton and cytoskeleton (LINC) complex, which plays critical roles in nuclear positioning, cell polarisation and cellular stiffness [].SUN1 contains a conserved Sad1p/UNC-84 (SUN)-domain at its C terminus that can associate with Klarsicht/ANC-1/Syne homology (KASH)-domain proteins []. The structure of the LINC complex has been solved []. In mammals, SUN1 is widely expressed and can bind to all four Nesprins (KASH-domain containing proteins) []. Sun1 and KASH5 are essential factors which mediate meiotic resumption and spindle formation [].
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Protein Coding Gene
MGI:1924303 | Sun1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26842404 | J:231308
 
First Author: Luo Y
Year: 2016
Journal: Sci Rep
Title: Depletion of the LINC complex disrupts cytoskeleton dynamics and meiotic resumption in mouse oocytes.
Volume: 6
Pages: 20408
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Publication
17543860 | J:122602
First Author: Ding X
Year: 2007
Journal: Dev Cell
Title: SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice.
Volume: 12
Issue: 6
Pages: 863-72
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Publication
22863315 | J:199760
First Author: Lei K
Year: 2012
Journal: Curr Biol
Title: Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response.
Volume: 22
Issue: 17
Pages: 1609-15
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Publication
18845190 | J:143409
First Author: Lu W
Year: 2008
Journal: Biochim Biophys Acta
Title: Sun1 forms immobile macromolecular assemblies at the nuclear envelope.
Volume: 1783
Issue: 12
Pages: 2415-26
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Publication
26035387 | J:224769
First Author: Wang JY
Year: 2015
Journal: Dis Model Mech
Title: Sun1 deficiency leads to cerebellar ataxia in mice.
Volume: 8
Issue: 8
Pages: 957-67
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Publication
16648470 | J:109072
First Author: Haque F
Year: 2006
Journal: Mol Cell Biol
Title: SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.
Volume: 26
Issue: 10
Pages: 3738-51
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Publication
19211677 | J:146636
First Author: Chi YH
Year: 2009
Journal: Development
Title: Requirement for Sun1 in the expression of meiotic reproductive genes and piRNA.
Volume: 136
Issue: 6
Pages: 965-73
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Publication
36989130 | J:337848
   
First Author: Buglak DB
Year: 2023
Journal: Elife
Title: Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation.
Volume: 12
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Publication
31686651 | J:291058
   
First Author: Loo TH
Year: 2019
Journal: Elife
Title: The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity.
Volume: 8
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Publication
19509342 | J:150047
First Author: Lei K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice.
Volume: 106
Issue: 25
Pages: 10207-12
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Publication
22541428 | J:186197
First Author: Chen CY
Year: 2012
Journal: Cell
Title: Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies.
Volume: 149
Issue: 3
Pages: 565-77
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Publication
16079285 | J:100177
First Author: Padmakumar VC
Year: 2005
Journal: J Cell Sci
Title: The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.
Volume: 118
Issue: Pt 15
Pages: 3419-30
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Publication
24586178 | J:211008
First Author: Link J
Year: 2014
Journal: PLoS Genet
Title: Analysis of meiosis in SUN1 deficient mice reveals a distinct role of SUN2 in mammalian meiotic LINC complex formation and function.
Volume: 10
Issue: 2
Pages: e1004099
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Protein
Q3TSM1
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
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Protein
E9LV88
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: true
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Protein
E9LV94
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Protein
F6XYA0
Organism: Mus musculus/domesticus
Length: 256  
Fragment?: true
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Protein
F7BX07
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: true
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Protein
D3Z1X3
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Protein
D3Z5Q2
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: true
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Protein
D3YUW9
Organism: Mus musculus/domesticus
Length: 175  
Fragment?: true
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Protein
D3Z3N5
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: true
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Protein
E9LV95
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
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Protein
E9LV85
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: true
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Protein
E9LV82
Organism: Mus musculus/domesticus
Length: 206  
Fragment?: true
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Protein
E9LV91
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Protein
D3Z0L7
Organism: Mus musculus/domesticus
Length: 53  
Fragment?: true
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Publication
22632968 | -
First Author: Sosa BA
Year: 2012
Journal: Cell
Title: LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.
Volume: 149
Issue: 5
Pages: 1035-47
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Protein
Q9D666
Organism: Mus musculus/domesticus
Length: 913  
Fragment?: false
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Publication
33686165 | J:305243
First Author: Hieda M
Year: 2021
Journal: Sci Rep
Title: The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.
Volume: 11
Issue: 1
Pages: 5358
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Protein
F7AJ01
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
F6RMJ1
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: true
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Publication
22945352 | -
First Author: Wang W
Year: 2012
Journal: Cell Res
Title: Structural insights into SUN-KASH complexes across the nuclear envelope.
Volume: 22
Issue: 10
Pages: 1440-52
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Publication
17158909 | -
First Author: Wilhelmsen K
Year: 2006
Journal: J Cell Sci
Title: KASH-domain proteins in nuclear migration, anchorage and other processes.
Volume: 119
Issue: Pt 24
Pages: 5021-9
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Publication
24797635 | J:214761
First Author: Liu W
Year: 2014
Journal: Dev Biol
Title: Phosphorylation of CDK2 at threonine 160 regulates meiotic pachytene and diplotene progression in mice.
Volume: 392
Issue: 1
Pages: 108-16
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Publication
23348741 | J:194486
First Author: Horn HF
Year: 2013
Journal: J Clin Invest
Title: The LINC complex is essential for hearing.
Volume: 123
Issue: 2
Pages: 740-50
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Publication
24589552 | J:209347
First Author: Ishiguro K
Year: 2014
Journal: Genes Dev
Title: Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes.
Volume: 28
Issue: 6
Pages: 594-607
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Publication
30373893 | J:266790
 
First Author: Feng Q
Year: 2018
Journal: J Cell Sci
Title: Mechanical forces on cellular organelles.
Volume: 131
Issue: 21
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Publication
25963820 | J:274648
First Author: Stewart RM
Year: 2015
Journal: J Cell Biol
Title: Nuclear-cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions.
Volume: 209
Issue: 3
Pages: 403-18
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Publication
21177258 | J:168852
First Author: Yu J
Year: 2011
Journal: Hum Mol Genet
Title: KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.
Volume: 20
Issue: 6
Pages: 1061-73
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Publication
19874786 | J:155113
First Author: Zhang X
Year: 2009
Journal: Neuron
Title: SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.
Volume: 64
Issue: 2
Pages: 173-87
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Publication
33779546 | J:304350
   
First Author: Carley E
Year: 2021
Journal: Elife
Title: The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation.
Volume: 10
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Publication
34039995 | J:340384
First Author: Chen Y
Year: 2021
Journal: Nat Commun
Title: The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Volume: 12
Issue: 1
Pages: 3176
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Publication
34354059 | J:341821
First Author: Chai RJ
Year: 2021
Journal: Nat Commun
Title: Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy.
Volume: 12
Issue: 1
Pages: 4722
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Publication
31935926 | J:315932
 
First Author: Porter L
Year: 2020
Journal: Cells
Title: SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells.
Volume: 9
Issue: 1
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Publication
23071752 | J:192230
First Author: Razafsky D
Year: 2012
Journal: PLoS One
Title: LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.
Volume: 7
Issue: 10
Pages: e47180
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Publication
25380821 | J:218218
First Author: Viera A
Year: 2015
Journal: J Cell Sci
Title: CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase.
Volume: 128
Issue: 1
Pages: 88-99
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Publication
19843581 | J:154595
First Author: Ostlund C
Year: 2009
Journal: J Cell Sci
Title: Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins.
Volume: 122
Issue: Pt 22
Pages: 4099-108
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Publication
20711465 | J:163755
First Author: Göb E
Year: 2010
Journal: PLoS One
Title: Mammalian sperm head formation involves different polarization of two novel LINC complexes.
Volume: 5
Issue: 8
Pages: e12072
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Publication
22826121 | J:190404
First Author: Morimoto A
Year: 2012
Journal: J Cell Biol
Title: A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.
Volume: 198
Issue: 2
Pages: 165-72
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Publication
30718482 | J:270644
First Author: Wang Y
Year: 2019
Journal: Nat Commun
Title: The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Volume: 10
Issue: 1
Pages: 564
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Publication
16380439 | J:104409
First Author: Crisp M
Year: 2006
Journal: J Cell Biol
Title: Coupling of the nucleus and cytoplasm: role of the LINC complex.
Volume: 172
Issue: 1
Pages: 41-53
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Publication
19933576 | J:159127
First Author: Haque F
Year: 2010
Journal: J Biol Chem
Title: Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.
Volume: 285
Issue: 5
Pages: 3487-98
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Publication
26548954 | J:228033
First Author: Shibuya H
Year: 2015
Journal: Cell
Title: MAJIN Links Telomeric DNA to the Nuclear Membrane by Exchanging Telomere Cap.
Volume: 163
Issue: 5
Pages: 1252-1266
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Publication
24885367 | J:242462
 
First Author: Daniel K
Year: 2014
Journal: BMC Cell Biol
Title: Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein.
Volume: 15
Pages: 17
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Publication
24413433 | J:205574
First Author: Shibuya H
Year: 2014
Journal: Nat Cell Biol
Title: The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosis.
Volume: 16
Issue: 2
Pages: 145-56
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Publication
29141207 | J:315957
First Author: Zhang J
Year: 2017
Journal: Cell Rep
Title: Distinct TERB1 Domains Regulate Different Protein Interactions in Meiotic Telomere Movement.
Volume: 21
Issue: 7
Pages: 1715-1726
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Publication
31350280 | J:279248
First Author: Palmer N
Year: 2019
Journal: J Cell Biol
Title: CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I.
Volume: 218
Issue: 9
Pages: 2896-2918
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Protein Coding Gene
MGP_CAROLIEiJ_G0027926 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030277 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030246 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030178 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030263 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029974 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1924303 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029379 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029944 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030049 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030080 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029453 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024498 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028930 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
Probe: MGI:5636863
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1852126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5637335
Age: embryonic day 18.5
Image: S4A
Note: Expression is localized in the nuclear envelope.
Specimen Label: S4A
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5636863
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1852126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5637335
Age: embryonic day 18.5
Image: S4B
Note: Expression is localized in the nuclear envelope; no differences in localization between these mice and wild type were observed.
Specimen Label: S4B
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5636863
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1852126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5637335
Age: embryonic day 18.5
Image: S4C
Note: Expression is localized in the nuclear envelope; no differences in localization between these mice and wild type were observed.
Specimen Label: S4C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5636863
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1852126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5637335
Age: embryonic day 18.5
Image: S4D
Note: Expression is localized in the nuclear envelope; no differences in localization between these mice and wild type were observed.
Specimen Label: S4D
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5636863
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1852126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5637335
Age: embryonic day 18.5
Image: S4E
Note: Expression is localized in the nuclear envelope; no differences in localization between these mice and wild type were observed.
Specimen Label: S4E
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:5636863
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-26
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5637335
Age: postnatal
Image: S2A
Specimen Label: S2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7580393
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7580401
Age: embryonic day 15.5
Image: S3 Figure 1A WT
Note: Expression is at the nuclear envelope in all cellular layers.
Specimen Label: S3 Figure 1A WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5636863
Assay Type: Immunohistochemistry
Annotation Date: 2015-05-26
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5637335
Age: postnatal
Image: S2A
Specimen Label: S2A
Detected: true
Specimen Num: 1
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Publication
37828059 | J:341625
First Author: Jiao S
Year: 2023
Journal: Nat Commun
Title: SUN1/2 controls macrophage polarization via modulating nuclear size and stiffness.
Volume: 14
Issue: 1
Pages: 6416
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Publication
29878215 | J:287130
First Author: Kozono T
Year: 2018
Journal: J Biochem
Title: Jaw1/LRMP has a role in maintaining nuclear shape via interaction with SUN proteins.
Volume: 164
Issue: 4
Pages: 303-311
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Publication
24062341 | J:201813
First Author: Horn HF
Year: 2013
Journal: J Cell Biol
Title: A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton.
Volume: 202
Issue: 7
Pages: 1023-39
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Publication
28966089 | J:277369
First Author: Gimpel P
Year: 2017
Journal: Curr Biol
Title: Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells.
Volume: 27
Issue: 19
Pages: 2999-3009.e9
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Publication
25892231 | J:228378
First Author: Lee CY
Year: 2015
Journal: Cell Rep
Title: Mechanism and regulation of rapid telomere prophase movements in mouse meiotic chromosomes.
Volume: 11
Issue: 4
Pages: 551-63
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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