Type |
Details |
Score |
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1450
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1450
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1429
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1144
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1437
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
84
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1450
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Yao CJ |
Year: |
2013 |
Journal: |
Pharmazie |
Title: |
Fanconi anemia pathway--the way of DNA interstrand cross-link repair. |
Volume: |
68 |
Issue: |
1 |
Pages: |
5-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamashita T |
Year: |
2001 |
Journal: |
Int J Hematol |
Title: |
Current knowledge on the pathophysiology of Fanconi anemia: from genes to phenotypes. |
Volume: |
74 |
Issue: |
1 |
Pages: |
33-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smogorzewska A |
Year: |
2010 |
Journal: |
Mol Cell |
Title: |
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. |
Volume: |
39 |
Issue: |
1 |
Pages: |
36-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kratz K |
Year: |
2010 |
Journal: |
Cell |
Title: |
Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents. |
Volume: |
142 |
Issue: |
1 |
Pages: |
77-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
MacKay C |
Year: |
2010 |
Journal: |
Cell |
Title: |
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. |
Volume: |
142 |
Issue: |
1 |
Pages: |
65-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamoto KN |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway. |
Volume: |
108 |
Issue: |
16 |
Pages: |
6492-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yeo JE |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
CtIP mediates replication fork recovery in a FANCD2-regulated manner. |
Volume: |
23 |
Issue: |
14 |
Pages: |
3695-705 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The Fanconi Anemia (FA) pathway is responsible for interstrand crosslink DNA repair []. The name originates the recessive syndrome known as Fanconi anemia, which causes developmental problems and cancer predisposition []. In this pathway, the FANCI-FANCD2 (ID) complex is ubiquitinated by the FA core complex and then travels to sites of damage to coordinate repair [, ]. FA pathway activation seems to trigger dissociation of FANCD2 from FANCI, coinciding with FANCD2 monoubiquitination which precedes monoubiquitination of FANCI []. This suggests a functional separation for FANCD2 from FANCI [].Monoubiquitinated FANCD2 functions to recruit DNA repair factors FAN1 (Fanconi-associated nuclease 1) []and SLX4 [], suggesting that chromatin-bound FANCD2Ub is a docking platform for certain DNA repair nucleases. FANCD2 has also a role in replication fork recovery []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
591
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
660
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
169
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
229
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
412
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
212
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
43
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
461
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
117
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
216
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
283
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
558
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [, ].This entry represents FANCC []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [, ].This entry represents FANCA []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
258
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson JB |
Year: |
2008 |
Journal: |
Oncogene |
Title: |
FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3. |
Volume: |
27 |
Issue: |
26 |
Pages: |
3641-52 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [, ].This entry represents the N-terminal domain of FANCA. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. This entry represents FANCG, which is part of the FA core complex required for the monoubiquitylation of FANCD2 and the FANCI heterodimer. The FA complex coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination []. Besides being part of the FA complex, FANCG also promotes formation of a protein complex containing BRCA2, FANCD2 and XRCC3 []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [, ].The FA group E protein (FANCE) has an important role in DNA repair, functioning as the FANCD2-binding protein in the FA core complex []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Blazek D |
Year: |
2011 |
Journal: |
Genes Dev |
Title: |
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes. |
Volume: |
25 |
Issue: |
20 |
Pages: |
2158-72 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1439
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1439
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
481
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
246
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
771
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhattacharjee S |
Year: |
2017 |
Journal: |
Cell Commun Signal |
Title: |
DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway. |
Volume: |
15 |
Issue: |
1 |
Pages: |
41 |
|
•
•
•
•
•
|
Publication |
First Author: |
van de Vrugt HJ |
Year: |
2011 |
Journal: |
DNA Repair (Amst) |
Title: |
Evidence for complete epistasis of null mutations in murine Fanconi anemia genes Fanca and Fancg. |
Volume: |
10 |
Issue: |
12 |
Pages: |
1252-61 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
879
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
421
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Alpi A |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination. |
Volume: |
27 |
Issue: |
24 |
Pages: |
8421-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meetei AR |
Year: |
2003 |
Journal: |
Nat Genet |
Title: |
A novel ubiquitin ligase is deficient in Fanconi anemia. |
Volume: |
35 |
Issue: |
2 |
Pages: |
165-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meetei AR |
Year: |
2004 |
Journal: |
Nat Genet |
Title: |
X-linked inheritance of Fanconi anemia complementation group B. |
Volume: |
36 |
Issue: |
11 |
Pages: |
1219-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato K |
Year: |
2012 |
Journal: |
Nucleic Acids Res |
Title: |
DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI. |
Volume: |
40 |
Issue: |
10 |
Pages: |
4553-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ling C |
Year: |
2007 |
Journal: |
EMBO J |
Title: |
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway. |
Volume: |
26 |
Issue: |
8 |
Pages: |
2104-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang TT |
Year: |
2006 |
Journal: |
Nat Rev Mol Cell Biol |
Title: |
Regulation of DNA repair by ubiquitylation. |
Volume: |
7 |
Issue: |
5 |
Pages: |
323-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang TT |
Year: |
2006 |
Journal: |
Nat Cell Biol |
Title: |
Regulation of monoubiquitinated PCNA by DUB autocleavage. |
Volume: |
8 |
Issue: |
4 |
Pages: |
339-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nijman SM |
Year: |
2005 |
Journal: |
Mol Cell |
Title: |
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. |
Volume: |
17 |
Issue: |
3 |
Pages: |
331-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moldovan GL |
Year: |
2009 |
Journal: |
Annu Rev Genet |
Title: |
How the fanconi anemia pathway guards the genome. |
Volume: |
43 |
|
Pages: |
223-49 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Fanconi anemia-associated protein of 24kDa (FAAP24) plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. It regulates FANCD2 monoubiquitination upon DNA damage. When repressed, it induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents. It targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA [].Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [, ]. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [, ].FANCL is an ubiquitin ligase that mediates monoubiquitination of FANCD2, a key step in the repair of interstrand DNA crosslinks (ICLs) in the Fanconi anemia (FA) pathway [, ]. In humans, defects in FANCL are the cause of Fanconi anemia complementation group L (FANCL). FANCL is a disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair [, ]. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Fanconi anemia-associated protein of 100kDa (FAAP100) is component of the Fanconi anemia (FA) core complex, which plays a central role in FA-associated DNA damage response. FAAP100 is essential for the stability and function of the complex [].Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [, ]. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Peptidase C19 contains ubiquitin hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquitinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl group of the C-terminal Gly residue of ubiquitin. The purpose of the de-ubiquitination is thought to be editing of the ubiquitin conjugates, which could rescue them from degradation, as well as recycling of the ubiquitin. The ubiquitin/proteasome system is responsible for most protein turnover in the mammalian cell, and with over 50 members, family C19 is one of the largest families of peptidases in the human genome [, ].This entry encompasses ubiquitin-specific hydrolase 1 (MEROPS identifier C19.019). It is required for deubiquitination of monoubiquitinated proteins involved in various DNA repair pathways and is a key regulator of DNA repair mechanisms []. Substrates include monoubiquitinated PCNA [], and components FANCD2 []and FANCI []of the Fanconi anemia pathway, a genetic disorder that resultsin the inability to monoubiquitinate these components []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [, ].Fanconi anemia group F protein (FANCF) is a component of the FA core complex [, ]. FANCF regulates its own expression by methylation at both mRNA and protein levels. Methylation-induced inactivation of FANCF has an important role on the occurrence of ovarian cancers by disrupting the FA-BRCA pathway [].This entry also includes homologues from plants. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Pennell S |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain. |
Volume: |
8 |
Issue: |
1 |
Pages: |
84-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Airik R |
Year: |
2016 |
Journal: |
J Am Soc Nephrol |
Title: |
A FANCD2/FANCI-Associated Nuclease 1-Knockout Model Develops Karyomegalic Interstitial Nephritis. |
Volume: |
27 |
Issue: |
12 |
Pages: |
3552-3559 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1868128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692889 |
Age: |
postnatal adult |
Image: |
UC Davis_1859386 |
Note: |
vas deferens |
Specimen Label: |
UC Davis_1859386 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692889 |
Age: |
postnatal adult |
Image: |
UC Davis_1859383 |
|
Specimen Label: |
UC Davis_1859383 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692889 |
Age: |
postnatal adult |
Image: |
UC Davis_1859384 |
|
Specimen Label: |
UC Davis_1859384 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692889 |
Age: |
postnatal adult |
Image: |
UC Davis_1859385 |
|
Specimen Label: |
UC Davis_1859385 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan Z |
Year: |
2010 |
Journal: |
Mol Cell |
Title: |
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. |
Volume: |
37 |
Issue: |
6 |
Pages: |
865-78 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
384
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
462
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
71
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
484
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
151
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
406
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
412
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
526
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
355
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
154
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
171
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Nookala RK |
Year: |
2007 |
Journal: |
Nucleic Acids Res |
Title: |
Insights into Fanconi Anaemia from the structure of human FANCE. |
Volume: |
35 |
Issue: |
5 |
Pages: |
1638-48 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
343
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Ciccia A |
Year: |
2007 |
Journal: |
Mol Cell |
Title: |
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. |
Volume: |
25 |
Issue: |
3 |
Pages: |
331-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2007 |
Journal: |
Nat Rev Genet |
Title: |
Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins. |
Volume: |
8 |
Issue: |
10 |
Pages: |
735-48 |
|
•
•
•
•
•
|