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Search results 301 to 400 out of 478 for Ranbp2

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Hits by Pathway

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Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869766
Specimen Label: UC Davis_1869766
Detected: true
Specimen Num: 81
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869747
Specimen Label: UC Davis_1869747
Detected: true
Specimen Num: 67
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869748
Specimen Label: UC Davis_1869748
Detected: true
Specimen Num: 68
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:360409
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6362890
Age: embryonic day 6.5
Image: E6.5
Specimen Label: E6.5
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:360409
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6362890
Age: embryonic day 6.5
Image: E6.5 - section a
Specimen Label: E6.5 - section a
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:360409
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:6362890
Age: embryonic day 6.5
Image: E6.5 - section b
Specimen Label: E6.5 - section b
Detected: true
Specimen Num: 3
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•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3604011
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6362890
Age: embryonic day 7.5
Image: E7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3604011
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6362890
Age: embryonic day 7.5
Image: E7.5 - section a
Specimen Label: E7.5 - section a
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3604011
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6362890
Age: embryonic day 7.5
Image: E7.5 - section b
Specimen Label: E7.5 - section b
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3604013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6362890
Age: embryonic day 8.5
Image: E8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 7
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869743
Specimen Label: UC Davis_1869743
Detected: true
Specimen Num: 63
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869744
Specimen Label: UC Davis_1869744
Detected: true
Specimen Num: 64
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869847
Specimen Label: UC Davis_1869847
Detected: true
Specimen Num: 156
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869848
Specimen Label: UC Davis_1869848
Detected: true
Specimen Num: 157
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869671
Specimen Label: UC Davis_1869671
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869672
Specimen Label: UC Davis_1869672
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869754
Specimen Label: UC Davis_1869754
Detected: true
Specimen Num: 72
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693029
Age: postnatal adult
Image: UC Davis_1869755
Specimen Label: UC Davis_1869755
Detected: true
Specimen Num: 73
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Publication
- | J:64933
   
First Author: Fauser S
Year: 2000
Journal: GenBank Submission
Title: Mus musculus Ran-binding protein 2 gene, complete cds
Pages: AF279458
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Publication
22262462 | J:197006
First Author: Saitoh N
Year: 2012
Journal: Mol Biol Cell
Title: The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.
Volume: 23
Issue: 6
Pages: 1115-28
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Publication
35771867 | J:331499
First Author: Kragness S
Year: 2022
Journal: PLoS One
Title: An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.
Volume: 17
Issue: 6
Pages: e0269404
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Publication
14697343 | J:87860
First Author: Olsson M
Year: 2004
Journal: Exp Cell Res
Title: Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.
Volume: 292
Issue: 2
Pages: 359-70
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Publication
31427429 | J:283037
 
First Author: Khalaf B
Year: 2019
Journal: J Cell Sci
Title: Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.
Volume: 132
Issue: 18
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Publication
12791264 | J:320054
First Author: Suntharalingam M
Year: 2003
Journal: Dev Cell
Title: Peering through the pore: nuclear pore complex structure, assembly, and function.
Volume: 4
Issue: 6
Pages: 775-89
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Publication
27717094 | J:315590
First Author: Fujiwara K
Year: 2016
Journal: Genes Cells
Title: Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.
Volume: 21
Issue: 11
Pages: 1176-1194
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Publication
- | J:279207
     
First Author: Mager J
Year: 2019
Journal: MGI Direct Data Submission
Title: A Catalog of Early Lethal KOMP Phenotypes
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Publication
- | J:72400
       
First Author: Mouse Genome Sequence and Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Mouse Genome Sequence Project Annotation
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•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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UniProt Feature
UniProt Feature
Begin: 1
Description: E3 SUMO-protein ligase RanBP2
Type: chain
End: 3053
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UniProt Feature
UniProt Feature
Begin: 57
Description: Interaction with RANBP2
Type: site
End: 57
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UniProt Feature
UniProt Feature
Begin: 25
Description: Interaction with RANBP2
Type: site
End: 25
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UniProt Feature
UniProt Feature
Begin: 4
Description: Interaction with RANBP2
Type: site
End: 4
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Gene
749339 | RGPD8
Type: gene
Organism: chimpanzee
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Publication
30333138 | J:266974
 
First Author: Wu K
Year: 2018
Journal: J Cell Sci
Title: GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking.
Volume: 131
Issue: 22
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Interaction Experiment
Pichler A (2002)
Description: The nucleoporin RanBP2 has SUMO1 E3 ligase activity.
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Publication
11792325 | -
First Author: Pichler A
Year: 2002
Journal: Cell
Title: The nucleoporin RanBP2 has SUMO1 E3 ligase activity.
Volume: 108
Issue: 1
Pages: 109-20
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Allele
Ranbp2<tm1Smoc> | MGI:7291970
Name: RAN binding protein 2; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
23641069 | -
First Author: Yoshimura SH
Year: 2013
Journal: J Cell Sci
Title: Intermolecular disulfide bonds between nucleoporins regulate karyopherin-dependent nuclear transport.
Volume: 126
Issue: Pt 14
Pages: 3141-50
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Publication
15037602 | -
First Author: Swaminathan S
Year: 2004
Journal: J Cell Biol
Title: RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly.
Volume: 164
Issue: 7
Pages: 965-71
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Publication
12032081 | -
First Author: Kirsh O
Year: 2002
Journal: EMBO J
Title: The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase.
Volume: 21
Issue: 11
Pages: 2682-91
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Publication
12874105 | -
First Author: Castagnet P
Year: 2003
Journal: Hum Mol Genet
Title: RPGRIP1s with distinct neuronal localization and biochemical properties associate selectively with RanBP2 in amacrine neurons.
Volume: 12
Issue: 15
Pages: 1847-63
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Publication
18946085 | -
First Author: Klein UR
Year: 2009
Journal: Mol Biol Cell
Title: RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin.
Volume: 20
Issue: 1
Pages: 410-8
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Strain
MGI:6429461 | C57BL/6J-Ranbp2<tm1Smoc>/Smoc
Attribute String: targeted mutation, mutant stock
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Publication
9019411 | J:38226
First Author: Mahajan R
Year: 1997
Journal: Cell
Title: A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2.
Volume: 88
Issue: 1
Pages: 97-107
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Publication
26321253 | J:228091
First Author: Liu H
Year: 2015
Journal: Mol Cell
Title: The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells.
Volume: 59
Issue: 5
Pages: 840-9
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Protein
Q9R020
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
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Protein
Q9D9Z2
Organism: Mus musculus/domesticus
Length: 185  
Fragment?: false
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Protein
A2AFS9
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
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Protein
A0A0G2JGA3
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
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Protein
A0A0G2JGE3
Organism: Mus musculus/domesticus
Length: 38  
Fragment?: false
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Protein
B2RRT9
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
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Protein
A0A1D5RLI7
Organism: Mus musculus/domesticus
Length: 502  
Fragment?: false
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Protein
D3Z4U0
Organism: Mus musculus/domesticus
Length: 320  
Fragment?: false
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Protein
Q3USF2
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: true
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Protein
Q3TQH3
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: true
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Protein
V9GX51
Organism: Mus musculus/domesticus
Length: 40  
Fragment?: false
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Protein
E9PUD0
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: false
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Publication
10318915 | -
First Author: Yaseen NR
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Two distinct classes of Ran-binding sites on the nucleoporin Nup-358.
Volume: 96
Issue: 10
Pages: 5516-21
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Protein Domain
IPR001876 | Znf_RanBP2
Type: Domain
Description: Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. Some of these domains bind zinc, but many do not; instead binding other metals such as iron, or no metal at all. For example, some family members form salt bridges to stabilise the finger-like folds. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis (African clawed frog), however they are now recognised to bind DNA, RNA, protein and/or lipid substrates [, , , , ]. Their binding properties depend on the amino acid sequence of the finger domains and of the linker between fingers, as well as on the higher-order structures and the number of fingers. Znf domains are often found in clusters, where fingers can have different binding specificities. There are many superfamilies of Znf motifs, varying in both sequence and structure. They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. For example, Znf-containing proteins function in gene transcription, translation, mRNA trafficking, cytoskeleton organisation, epithelial development, cell adhesion, protein folding, chromatin remodelling and zinc sensing, to name but a few []. Zinc-binding motifs are stable structures, and they rarely undergo conformational changes upon binding their target. This entry representsthe zinc finger domain found in RanBP2 proteins. Ran is an evolutionary conserved member of the Ras superfamily that regulates all receptor-mediated transport between the nucleus and the cytoplasm. Ran binding protein 2 (RanBP2) is a 358kDa nucleoporin located on the cytoplasmic side of the nuclear pore complex which plays a role in nuclear protein import []. RanBP2 contains multiple zinc fingers which mediate binding to RanGDP [].
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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