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Search results 201 to 214 out of 214 for Tiam2

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0.016s

Type

Details

Score

Publication

12912917 | -

First Author:	Kawauchi T
Year:	2003
Journal:	EMBO J
Title:	The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration.
Volume:	22
Issue:	16
Pages:	4190-201

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Protein Domain

IPR040655 | TIAM1_CC-Ex

Type:

Domain

Description:

Tiam1 is a guanine exchange factor (GEF) for CDC42 and the Rho-family GTPase Rac1, which plays an important role in cell-matrix adhesion and in cell migration [, ]. Tiam1 is involved in multiple steps of tumorigenesis [].This entry represents the CC and Ex subdomain found in the PH-CC-Ex globular domain of the Tiam1 and Tiam2 proteins (T-lymphoma invasion and metastasis). The CC subdomain forms an antiparallel coiled coil with two long α-helices, together with the C-terminal Ex subdomain they form a small globular domain comprising three α-helices. The CC subdomain of the Tiam2 PHCCEx domain follows the C-terminal alpha1 helix of the PH subdomain through a four-residue linker [].

•

Publication

17320046 | -

First Author:	Takefuji M
Year:	2007
Journal:	Biochem Biophys Res Commun
Title:	Rho-kinase modulates the function of STEF, a Rac GEF, through its phosphorylation.
Volume:	355
Issue:	3
Pages:	788-94

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Publication

20361982 | -

First Author:	Shepherd TR
Year:	2010
Journal:	J Mol Biol
Title:	The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
Volume:	398
Issue:	5
Pages:	730-46

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Publication

26887924 | J:234739

First Author:	Marei H
Year:	2016
Journal:	Nat Commun
Title:	Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration.
Volume:	7

Pages:	10664

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Publication

24308970 | -

First Author:	Boissier P
Year:	2014
Journal:	Cell Signal
Title:	The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
Volume:	26
Issue:	3
Pages:	483-91

•

Publication

24470589 | J:332276

First Author:	Boespflug ND
Year:	2014
Journal:	Blood
Title:	ATF3 is a novel regulator of mouse neutrophil migration.
Volume:	123
Issue:	13
Pages:	2084-93

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Protein

Q6P1D6

Organism:	Mus musculus/domesticus
Length:	900
Fragment?:	false

•

Protein

Q60610

Organism:	Mus musculus/domesticus
Length:	1591
Fragment?:	false

•

Protein

G3UWG2

Organism:	Mus musculus/domesticus
Length:	1591
Fragment?:	false

•

Protein

Q3UHH6

Organism:	Mus musculus/domesticus
Length:	1496
Fragment?:	false

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

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Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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