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Search results 1201 to 1210 out of 1210 for Epha5

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0.018s

Type

Details

Score

Publication

9321687 | -

First Author:	Caras IW
Year:	1997
Journal:	Cell Tissue Res
Title:	A link between axon guidance and axon fasciculation suggested by studies of the tyrosine kinase receptor EphA5/REK7 and its ligand ephrin-A5/AL-1.
Volume:	290
Issue:	2
Pages:	261-4

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Protein Domain

IPR034277 | EphA5_rcpt_lig-bd

Type:

Domain

Description:

This entry represents the ligand-binding domain found in ephrin type-A receptor 5 (EphA5), also known as brain-specific kinase (Bsk). EphA5 is almost exclusively expressed in the nervous system, and is thought to play a role in synaptogenesis, and in dorsoventral organization of the spinal cord [, , ].Class EphA receptors bind GPI-anchored ephrin-A ligands. There are ten vertebrate EphA receptors (EphA1-10), which display promiscuous interactions with six ephrin-A ligands [, ]. Ephrin receptors (EphRs) comprise the largest subfamily of receptor tyrosine kinases (RTKs). EphRs contain a ligand binding domain and two fibronectin repeats extracellularly, a transmembrane segment, and a cytoplasmic tyrosine kinase domain. Binding of the ephrin ligand to EphR requires cell-cell contact since both are anchored to the plasma membrane. The resulting downstream signals occur bidirectionally in both EphR-expressing cells (forward signaling) and ephrin-expressing cells (reverse signaling) [].

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Publication

17129788 | J:144662

First Author:	Serizawa S
Year:	2006
Journal:	Cell
Title:	A neuronal identity code for the odorant receptor-specific and activity-dependent axon sorting.
Volume:	127
Issue:	5
Pages:	1057-69

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HT Experiment

GSE207853 | Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

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Publication

24956127 | J:217005

First Author:	Liu S
Year:	2014
Journal:	Endocrinology
Title:	Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects β-cell function.
Volume:	155
Issue:	9
Pages:	3329-38

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Publication

18619851 | J:141860

First Author:	Peuckert C
Year:	2008
Journal:	Mol Cell Neurosci
Title:	Adaptive changes in gene expression patterns in the somatosensory cortex after deletion of ephrinA5.
Volume:	39
Issue:	1
Pages:	21-31

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Publication

15924339 | J:99706

First Author:	Ellsworth CA
Year:	2005
Journal:	J Comp Neurol
Title:	Ephrin-A2 and -A5 influence patterning of normal and novel retinal projections to the thalamus: conserved mapping mechanisms in visual and auditory thalamic targets.
Volume:	488
Issue:	2
Pages:	140-51

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Publication

24814534 | J:214335

First Author:	Pattabiraman K
Year:	2014
Journal:	Neuron
Title:	Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex.
Volume:	82
Issue:	5
Pages:	989-1003

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Publication

18413883 | -

First Author:	Lackmann M
Year:	2008
Journal:	Sci Signal
Title:	Eph, a protein family coming of age: more confusion, insight, or complexity?
Volume:	1
Issue:	15
Pages:	re2

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Publication

12495863 | -

First Author:	Himanen JP
Year:	2003
Journal:	Trends Neurosci
Title:	Eph signaling: a structural view.
Volume:	26
Issue:	1
Pages:	46-51

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