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Search results 4001 to 4100 out of 7122 for App

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Type Details Score
Publication
33446720 | J:300672
First Author: Kang S
Year: 2021
Journal: Sci Rep
Title: Spatial memory deficiency early in 6xTg Alzheimer's disease mouse model.
Volume: 11
Issue: 1
Pages: 1334
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Publication
38309272 | J:346654
First Author: Lan Y
Year: 2024
Journal: Immunity
Title: Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury.
Volume: 57
Issue: 2
Pages: 349-363.e9
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Publication
34148071 | J:311242
First Author: Ries M
Year: 2021
Journal: Brain
Title: Annexin A1 restores cerebrovascular integrity concomitant with reduced amyloid-β and tau pathology.
Volume: 144
Issue: 5
Pages: 1526-1541
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Publication
34133945 | J:311292
First Author: Lall D
Year: 2021
Journal: Neuron
Title: C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation.
Volume: 109
Issue: 14
Pages: 2275-2291.e8
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Publication
38961225 | J:359458
First Author: Rosenzweig N
Year: 2024
Journal: Nat Med
Title: Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease.
Volume: 30
Issue: 10
Pages: 2990-3003
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Publication
31967645 | J:289881
 
First Author: Reed-Geaghan EG
Year: 2020
Journal: J Exp Med
Title: Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model.
Volume: 217
Issue: 4
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Publication
38418876 | J:349898
First Author: Murdock MH
Year: 2024
Journal: Nature
Title: Multisensory gamma stimulation promotes glymphatic clearance of amyloid.
Volume: 627
Issue: 8002
Pages: 149-156
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Publication
38821054 | J:349784
First Author: Barclay KM
Year: 2024
Journal: Immunity
Title: An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination.
Volume: 57
Issue: 6
Pages: 1394-1412.e8
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Publication
17451844 | J:140912
First Author: Golub MS
Year: 2008
Journal: Neurobiol Aging
Title: Behavioral consequences of ovarian atrophy and estrogen replacement in the APPswe mouse.
Volume: 29
Issue: 10
Pages: 1512-23
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Publication
18762354 | J:161991
First Author: Cheng H
Year: 2010
Journal: Neurobiol Aging
Title: Apolipoprotein E mediates sulfatide depletion in animal models of Alzheimer's disease.
Volume: 31
Issue: 7
Pages: 1188-96
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Publication
28455100 | J:252258
 
First Author: Piiponniemi TO
Year: 2017
Journal: Neurosci Lett
Title: Acquisition and reversal of visual discrimination learning in APPSwDI/Nos2-/- (CVN) mice.
Volume: 650
Pages: 126-133
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Publication
19553436 | J:150418
First Author: Wilcock DM
Year: 2009
Journal: J Neurosci
Title: Amyloid reduction by amyloid-beta vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease.
Volume: 29
Issue: 25
Pages: 7957-65
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Publication
18272675 | J:132221
First Author: Wilcock DM
Year: 2008
Journal: J Neurosci
Title: Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2.
Volume: 28
Issue: 7
Pages: 1537-45
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Publication
27466341 | J:234626
First Author: Spencer B
Year: 2016
Journal: J Neurosci
Title: Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model.
Volume: 36
Issue: 30
Pages: 7971-84
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Publication
19587288 | J:151080
First Author: Dziewczapolski G
Year: 2009
Journal: J Neurosci
Title: Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease.
Volume: 29
Issue: 27
Pages: 8805-15
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Publication
16103124 | J:128865
First Author: Hass MR
Year: 2005
Journal: J Biol Chem
Title: A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein.
Volume: 280
Issue: 44
Pages: 36895-904
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Publication
33519806 | J:311569
 
First Author: Ma C
Year: 2020
Journal: Front Immunol
Title: Arginase 1 Insufficiency Precipitates Amyloid-β Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis.
Volume: 11
Pages: 582998
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Publication
31878336 | J:346775
 
First Author: Leparulo A
Year: 2019
Journal: Cells
Title: Dampened Slow Oscillation Connectivity Anticipates Amyloid Deposition in the PS2APP Mouse Model of Alzheimer's Disease.
Volume: 9
Issue: 1
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Publication
26885753 | J:255079
First Author: Chaput D
Year: 2016
Journal: Oncotarget
Title: Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology.
Volume: 7
Issue: 8
Pages: 8481-97
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Publication
24899710 | J:244396
First Author: Fowler SW
Year: 2014
Journal: J Neurosci
Title: Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease.
Volume: 34
Issue: 23
Pages: 7871-85
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Publication
23447589 | J:195259
First Author: Melnikova T
Year: 2013
Journal: J Neurosci
Title: Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis.
Volume: 33
Issue: 9
Pages: 3765-79
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Publication
14980807 | J:100955
First Author: Hwang DY
Year: 2004
Journal: Exp Neurol
Title: Aberrant expressions of pathogenic phenotype in Alzheimer's diseased transgenic mice carrying NSE-controlled APPsw.
Volume: 186
Issue: 1
Pages: 20-32
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Publication
20817351 | J:188228
First Author: Lagadec S
Year: 2012
Journal: Neurobiol Aging
Title: Early temporal short-term memory deficits in double transgenic APP/PS1 mice.
Volume: 33
Issue: 1
Pages: 203.e1-11
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Publication
24990930 | J:212536
First Author: Ishii M
Year: 2014
Journal: J Neurosci
Title: Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons.
Volume: 34
Issue: 27
Pages: 9096-106
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Publication
18509040 | J:136387
First Author: Richard KL
Year: 2008
Journal: J Neurosci
Title: Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease.
Volume: 28
Issue: 22
Pages: 5784-93
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Publication
12831872 | J:100957
First Author: van Groen T
Year: 2003
Journal: Neuroscience
Title: Diffuse amyloid deposition, but not plaque number, is reduced in amyloid precursor protein/presenilin 1 double-transgenic mice by pathway lesions.
Volume: 119
Issue: 4
Pages: 1185-97
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Publication
12559106 | J:128594
First Author: Wang J
Year: 2003
Journal: Neuroscience
Title: Altered auditory-evoked potentials in mice carrying mutated human amyloid precursor protein and presenilin-1 transgenes.
Volume: 116
Issue: 2
Pages: 511-7
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Publication
12742257 | J:130974
First Author: Iivonen H
Year: 2003
Journal: Behav Brain Res
Title: Hypothermia in mice tested in Morris water maze.
Volume: 141
Issue: 2
Pages: 207-13
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Publication
18354008 | J:133211
First Author: Rohn TT
Year: 2008
Journal: J Neurosci
Title: Lack of pathology in a triple transgenic mouse model of Alzheimer's disease after overexpression of the anti-apoptotic protein Bcl-2.
Volume: 28
Issue: 12
Pages: 3051-9
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Publication
21266456 | J:170123
First Author: Trazzi S
Year: 2011
Journal: Hum Mol Genet
Title: APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
Volume: 20
Issue: 8
Pages: 1560-73
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Publication
15869949 | J:99662
First Author: Seo H
Year: 2005
Journal: Exp Neurol
Title: Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice.
Volume: 193
Issue: 2
Pages: 469-80
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Publication
18180075 | J:152960
First Author: Chen Y
Year: 2009
Journal: Neurobiol Aging
Title: In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model.
Volume: 30
Issue: 9
Pages: 1453-65
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Publication
24636797 | J:211994
 
First Author: Trazzi S
Year: 2014
Journal: Neurobiol Dis
Title: APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome.
Volume: 67
Pages: 24-36
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Publication
12657457 | J:95710
First Author: Hunter CL
Year: 2003
Journal: Neurosci Res
Title: Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome.
Volume: 45
Issue: 4
Pages: 437-45
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Publication
18840503 | J:143417
First Author: Van Broeck B
Year: 2008
Journal: Neurosci Lett
Title: Reduced brain volumes in mice expressing APP-Austrian mutation but not in mice expressing APP-Swedish-Austrian mutations.
Volume: 447
Issue: 2-3
Pages: 143-7
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Publication
27427974 | J:317872
First Author: Pajares M
Year: 2016
Journal: Autophagy
Title: Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.
Volume: 12
Issue: 10
Pages: 1902-1916
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Publication
26235435 | J:226267
 
First Author: Lonskaya I
Year: 2015
Journal: Neuroscience
Title: Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models.
Volume: 304
Pages: 316-27
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Publication
25557380 | J:350948
First Author: Kniewallner KM
Year: 2015
Journal: Curr Neurovasc Res
Title: Platelets in the Alzheimer's disease brain: do they play a role in cerebral amyloid angiopathy?
Volume: 12
Issue: 1
Pages: 4-14
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Publication
30341392 | J:270046
First Author: Kniewallner KM
Year: 2018
Journal: Sci Rep
Title: Platelets isolated from an Alzheimer mouse damage healthy cortical vessels and cause inflammation in an organotypic ex vivo brain slice model.
Volume: 8
Issue: 1
Pages: 15483
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Publication
15311281 | J:92796
First Author: Herzig MC
Year: 2004
Journal: Nat Neurosci
Title: Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.
Volume: 7
Issue: 9
Pages: 954-60
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Publication
25231903 | J:217304
First Author: Tagawa K
Year: 2015
Journal: Hum Mol Genet
Title: Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain.
Volume: 24
Issue: 2
Pages: 540-58
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Publication
9574821 | J:45852
First Author: Panegyres PK
Year: 1997
Journal: Neuropeptides
Title: The amyloid precursor protein gene: a neuropeptide gene with diverse functions in the central nervous system.
Volume: 31
Issue: 6
Pages: 523-35
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Publication
31186474 | J:281479
First Author: Shin MK
Year: 2019
Journal: Sci Rep
Title: Ganglioside GQ1b ameliorates cognitive impairments in an Alzheimer's disease mouse model, and causes reduction of amyloid precursor protein.
Volume: 9
Issue: 1
Pages: 8512
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Publication
23034916 | J:315904
First Author: Chu J
Year: 2012
Journal: Ann Neurol
Title: 5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of Alzheimer disease.
Volume: 72
Issue: 3
Pages: 442-54
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Publication
29847796 | J:270730
First Author: Flamier A
Year: 2018
Journal: Cell Rep
Title: Modeling Late-Onset Sporadic Alzheimer's Disease through BMI1 Deficiency.
Volume: 23
Issue: 9
Pages: 2653-2666
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Publication
16504943 | J:107582
First Author: Caccamo A
Year: 2006
Journal: Neuron
Title: M1 receptors play a central role in modulating AD-like pathology in transgenic mice.
Volume: 49
Issue: 5
Pages: 671-82
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Publication
16039562 | J:101023
First Author: McGowan E
Year: 2005
Journal: Neuron
Title: Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.
Volume: 47
Issue: 2
Pages: 191-199
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Publication
17596450 | J:122975
First Author: Lazarov O
Year: 2007
Journal: J Neurosci
Title: Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1.
Volume: 27
Issue: 26
Pages: 7011-20
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Publication
11709540 | J:72987
First Author: Lesuisse C
Year: 2001
Journal: Hum Mol Genet
Title: Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice.
Volume: 10
Issue: 22
Pages: 2525-37
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Publication
9450754 | J:71037
First Author: De Strooper B
Year: 1998
Journal: Nature
Title: Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein.
Volume: 391
Issue: 6665
Pages: 387-90
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Protein Domain
IPR009119 | BACE
Type: Family
Description: One of the major neuropathological hallmarks of Alzheimer's disease (AD)is the progressive formation in the brain of insoluble amyloid plaques and vascular deposits consisting of beta-amyloid protein (beta-APP) [].Production of beta-APP requires proteolytic cleavage of the large type-1 transmembrane (TM) protein amyloid precursor protein (APP) []. This processis performed by a variety of enzymes known as secretases. To initiate beta-APP formation, beta-secretase cleaves APP to release a soluble N-terminal fragment (APPsBeta) and a C-terminal fragment that remains membrane bound. This fragment is subsequently cleaved by gamma-secretase to liberate beta-APP.Several independent studies identified a novel TM aspartic protease as themajor beta-secretase [, , ]. This protein, termed beta-site APP cleavingenzyme 1 (BACE1), shares 64% amino acid sequence similarity with a secondenzyme, termed BACE2. Together, BACE1 and BACE2 define a novel family of aspartyl proteases []. Both enzymes share significant sequence similaritywith other members of the pepsin family of aspartyl proteases and contain the two characteristic D(T/S)G(T/S) motifs that form the catalytic site.However, by contrast with other aspartyl proteases, BACE1 and BACE2 aretype I TM proteins. Each protein comprises a large lumenal domain containingthe active centre, a single TM domain and a small cytoplasmic tail.
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Publication
23382922 | J:195915
First Author: Maulik M
Year: 2013
Journal: PLoS One
Title: Alterations in gene expression in mutant amyloid precursor protein transgenic mice lacking Niemann-Pick type C1 protein.
Volume: 8
Issue: 1
Pages: e54605
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Publication
20679486 | J:164904
First Author: Eroglu B
Year: 2010
Journal: Mol Cell Biol
Title: Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta.
Volume: 30
Issue: 19
Pages: 4626-43
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Publication
25946042 | J:235351
First Author: Liu P
Year: 2015
Journal: PLoS One
Title: Characterization of a Novel Mouse Model of Alzheimer's Disease--Amyloid Pathology and Unique β-Amyloid Oligomer Profile.
Volume: 10
Issue: 5
Pages: e0126317
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Publication
27466343 | J:234625
First Author: Huang TY
Year: 2016
Journal: J Neurosci
Title: SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein.
Volume: 36
Issue: 30
Pages: 7996-8011
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Publication
38104129 | J:348471
First Author: Chen J
Year: 2023
Journal: Transl Psychiatry
Title: Amyloid precursor protein facilitates SARS-CoV-2 virus entry into cells and enhances amyloid-β-associated pathology in APP/PS1 mouse model of Alzheimer's disease.
Volume: 13
Issue: 1
Pages: 396
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Publication
11978821 | J:87229
First Author: Dewachter I
Year: 2002
Journal: J Neurosci
Title: Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
Volume: 22
Issue: 9
Pages: 3445-53
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Publication
33516914 | J:322056
 
First Author: Lanzillotta C
Year: 2021
Journal: Free Radic Biol Med
Title: Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndrome.
Volume: 165
Pages: 152-170
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Publication
25474204 | J:225685
First Author: Lysenko LV
Year: 2014
Journal: PLoS One
Title: Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome.
Volume: 9
Issue: 12
Pages: e114521
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Publication
33161213 | J:305383
 
First Author: Hendrix RD
Year: 2021
Journal: Neurobiol Aging
Title: Alzheimer amyloid-β- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood.
Volume: 97
Pages: 73-88
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Publication
25830951 | J:233423
First Author: Hohsfield LA
Year: 2015
Journal: PLoS One
Title: Intravenous infusion of monocytes isolated from 2-week-old mice enhances clearance of Beta-amyloid plaques in an Alzheimer mouse model.
Volume: 10
Issue: 4
Pages: e0121930
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Publication
23747948 | J:199082
First Author: Frost JL
Year: 2013
Journal: Am J Pathol
Title: Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models.
Volume: 183
Issue: 2
Pages: 369-81
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Publication
28690498 | J:288833
 
First Author: Han K
Year: 2017
Journal: Front Mol Neurosci
Title: Amyloid-precursor Like Proteins APLP1 and APLP2 Are Dispensable for Normal Development of the Neonatal Respiratory Network.
Volume: 10
Pages: 189
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Transgene
MGI:5550545 | Tg(NEFL-APP)#Nalb
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:2448606 | Tg(APP695)3Dbo
Type: transgene
Organism: mouse, laboratory
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Allele
App<tm1Ini> | MGI:3044176
Name: amyloid beta precursor protein; targeted mutation 1, Ikuo Nishimoto
Allele Type: Targeted
Attribute String: Humanized sequence
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Transgene
MGI:3696074 | Tg(tetO-APPSwInd)885Dbo
Type: transgene
Organism: mouse, laboratory
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Allele
Tg(Prnp-App/APPswe)E1-2Dbo | MGI:3696473
Name: transgene insertion E1-2, David R Borchelt
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Transgene
MGI:3710685 | Tg(Prnp-ITM2B/APP695*42)A12Emcg
Type: transgene
Organism: mouse, laboratory
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Allele
Tg(CAG-APP)0304Shoj | MGI:3720041
Name: transgene insertion 0304, Mikio Shoji
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Transgene
MGI:3765348 | Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4412049 | Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5463434 | Tg(Thy1-APPArc)M8Cagr
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5634328 | Tg(Eno2-APP*Ind)#Kakiz
Type: transgene
Organism: mouse, laboratory
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Allele
Tg(tetO/Prnp-APP*Swe*Lon)9191Krz | MGI:5803807
Name: transgene insertion 9191, Kathleen R Zahs
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Tg(Myh6*/tetO-Hspb8*K141N)#Atsa | MGI:6294491
Name: transgene insertion, Atsushi Sanbe
Allele Type: Transgenic
Attribute String: Epitope tag, Inducible, Inserted expressed sequence
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Genotype
Genotype
Symbol: Ide/Ide
Background: involves: 129S5/SvEvBrd * C57BL/6-Tyr
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Tg(tetO-APPSwInd)885Dbo/?
Background: involves: C3H/HeJ * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mapt/Mapt<+> Zbtb20/?
Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mapt/Mapt Zbtb20/?
Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Camk2a-IDE)1Selk/? Zbtb20/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Camk2a-MME)3Selk/? Zbtb20/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(Thy1-cre)1Vln/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(Camk2a-cre)1Shn/?
Background: involves: 129S4/SvJae * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(Camk2a-cre)1Shn/?
Background: involves: 129S4/SvJae * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APPSw)10Jiri/? Tg(Thy1-PSEN1*M146V)#Jiri/?
Background: involves: C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/?
Background: D2.Cg-Tg(APPswe,PSEN1dE9)85Dbo
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Publication
22674275 | J:278371
First Author: William CM
Year: 2012
Journal: J Neurosci
Title: Synaptic plasticity defect following visual deprivation in Alzheimer's disease model transgenic mice.
Volume: 32
Issue: 23
Pages: 8004-11
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Publication
18304698 | J:152955
First Author: Oh ES
Year: 2009
Journal: Neurobiol Aging
Title: Amyloid precursor protein increases cortical neuron size in transgenic mice.
Volume: 30
Issue: 8
Pages: 1238-44
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Publication
27267879 | J:316712
First Author: Dinet V
Year: 2016
Journal: Mol Brain
Title: Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics.
Volume: 9
Issue: 1
Pages: 64
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Publication
23201095 | J:196979
 
First Author: Kida E
Year: 2013
Journal: Exp Neurol
Title: Long-term running alleviates some behavioral and molecular abnormalities in Down syndrome mouse model Ts65Dn.
Volume: 240
Pages: 178-89
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Publication
16574645 | J:113453
First Author: Wang R
Year: 2006
Journal: J Biol Chem
Title: Wild-type presenilin 1 protects against Alzheimer disease mutation-induced amyloid pathology.
Volume: 281
Issue: 22
Pages: 15330-6
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Publication
16400027 | J:104442
First Author: Van Dooren T
Year: 2006
Journal: Am J Pathol
Title: Neuronal or glial expression of human apolipoprotein e4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgenic mice.
Volume: 168
Issue: 1
Pages: 245-60
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Publication
10077666 | J:100974
First Author: Hsia AY
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models.
Volume: 96
Issue: 6
Pages: 3228-33
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Publication
18586097 | J:138611
First Author: Zhou XW
Year: 2008
Journal: Neurobiol Dis
Title: Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A.
Volume: 31
Issue: 3
Pages: 386-94
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Publication
24599465 | J:209619
First Author: Veeraraghavalu K
Year: 2014
Journal: J Neurosci
Title: Age-dependent, non-cell-autonomous deposition of amyloid from synthesis of β-amyloid by cells other than excitatory neurons.
Volume: 34
Issue: 10
Pages: 3668-73
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Publication
21411653 | J:308682
First Author: Wang A
Year: 2011
Journal: J Neurosci
Title: Robust amyloid clearance in a mouse model of Alzheimer's disease provides novel insights into the mechanism of amyloid-beta immunotherapy.
Volume: 31
Issue: 11
Pages: 4124-36
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Publication
21957232 | J:176127
First Author: Cheng N
Year: 2011
Journal: J Neurosci
Title: In vivo olfactory model of APP-induced neurodegeneration reveals a reversible cell-autonomous function.
Volume: 31
Issue: 39
Pages: 13699-704
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Publication
24174666 | J:204201
First Author: Yetman MJ
Year: 2013
Journal: J Neurosci
Title: Wild-type neural progenitors divide and differentiate normally in an amyloid-rich environment.
Volume: 33
Issue: 44
Pages: 17335-41
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