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Search results 2801 to 2867 out of 2867 for Kdr

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Type Details Score
Publication
19253403 | J:151276
First Author: Poché RA
Year: 2009
Journal: Dev Dyn
Title: The Flk1-myr::mCherry mouse as a useful reporter to characterize multiple aspects of ocular blood vessel development and disease.
Volume: 238
Issue: 9
Pages: 2318-26
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Publication
24713391 | J:210963
First Author: San Martin R
Year: 2014
Journal: Am J Pathol
Title: Recruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis.
Volume: 184
Issue: 6
Pages: 1860-70
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Publication
19248165 | J:155859
First Author: Larina IV
Year: 2009
Journal: Anat Rec (Hoboken)
Title: A membrane associated mCherry fluorescent reporter line for studying vascular remodeling and cardiac function during murine embryonic development.
Volume: 292
Issue: 3
Pages: 333-41
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Strain
MGI:7718107 | C57BL/6JSmoc-Rag2<em1Smoc> Kdr<tm2(KDR)Smoc> Il2rg<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Tg(Kdr-mCherry)1Medi/?
Background: involves: 129S/SvEv * FVB
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Kdr-mCherry)1Medi/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
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Allele
Tg(Kdr-cre)15962Brei | MGI:3038968
Name: transgene insertion 15962, George Breier
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Kdr-cre)15964Brei | MGI:3038972
Name: transgene insertion 15964, George Breier
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
37695302 | J:358185
First Author: Hunter R
Year: 2023
Journal: Toxicol Sci
Title: Gestational ozone inhalation elicits maternal cardiac dysfunction and transcriptional changes to placental pericytes and endothelial cells.
Volume: 196
Issue: 2
Pages: 238-249
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Publication
17251488 | J:123331
First Author: Kaji Y
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: Inhibition of diabetic leukostasis and blood-retinal barrier breakdown with a soluble form of a receptor for advanced glycation end products.
Volume: 48
Issue: 2
Pages: 858-65
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Publication
30452882 | J:287995
First Author: Miyoshi A
Year: 2019
Journal: FASEB J
Title: JNK and ATF4 as two important platforms for tumor necrosis factor-α-stimulated shedding of receptor for advanced glycation end products.
Volume: 33
Issue: 3
Pages: 3575-3589
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Allele
Tg(tetO-Kdr*)4377.5Rwng | MGI:3810550
Name: transgene insertion 4377.5, Rong Wang
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Allele
Tg(Kdr-cre)#Brei | MGI:5428039
Name: transgene insertion, George Breier
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
34273271 | J:335929
First Author: Bertoglio F
Year: 2021
Journal: Cell Rep
Title: A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations.
Volume: 36
Issue: 4
Pages: 109433
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Publication
24004946 | J:204523
First Author: Udan RS
Year: 2013
Journal: Development
Title: Dynamic responses of endothelial cells to changes in blood flow during vascular remodeling of the mouse yolk sac.
Volume: 140
Issue: 19
Pages: 4041-50
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Publication
30820471 | J:278025
 
First Author: Yamamoto Y
Year: 2019
Journal: Commun Biol
Title: Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice.
Volume: 2
Pages: 76
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Allele
Tg(Kdr-TVA)1026Ebp | MGI:5296521
Name: transgene insertion 1026, Elena Pasquale
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Plxnd1/Plxnd1 Tg(Kdr-mCherry)1Medi/?
Background: involves: 129S/SvEv * FVB
Zygosity: cx
Has Mutant Allele: true
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Publication
11457879 | J:70495
First Author: Yamamoto Y
Year: 2001
Journal: J Clin Invest
Title: Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice.
Volume: 108
Issue: 2
Pages: 261-8
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Strain
MGI:3810931 | FVB-Tg(tetO-Kdr*)4377.5Rwng/J
Attribute String: coisogenic, transgenic
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Publication
25688651 | J:237324
First Author: Zhu J
Year: 2015
Journal: FEBS J
Title: Simultaneous in vivo imaging of blood and lymphatic vessel growth in Prox1-GFP/Flk1::myr-mCherry mice.
Volume: 282
Issue: 8
Pages: 1458-1467
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Publication
21173261 | J:169003
First Author: Cool J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning.
Volume: 108
Issue: 1
Pages: 167-72
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Strain
MGI:5296522 | FVB/N-Tg(Kdr-TVA)1026Ebp/J
Attribute String: coisogenic, mutant strain, transgenic
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Publication
30126991 | J:265539
First Author: Naveh GRS
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Nonuniformity in ligaments is a structural strategy for optimizing functionality.
Volume: 115
Issue: 36
Pages: 9008-9013
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Genotype
Genotype
Symbol: Tg(Ins2-Nos2)40Okam/? Tg(Kdr-AGER)102Hyam/?
Background: involves: C57BL/6J * CBA/J * CD-1 * DBA/2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(tetO-Kdr*)4377.5Rwng/? Tg(Cebpb-tTA)5Bjd/?
Background: involves: FVB/N * NMRI
Zygosity: cx
Has Mutant Allele: true
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Publication
1656371 | J:14650
First Author: Terman BI
Year: 1991
Journal: Oncogene
Title: Identification of a new endothelial cell growth factor receptor tyrosine kinase.
Volume: 6
Issue: 9
Pages: 1677-83
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Publication
12887919 | -
First Author: Seo DW
Year: 2003
Journal: Cell
Title: TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism.
Volume: 114
Issue: 2
Pages: 171-80
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Publication
11710594 | -
First Author: Chattopadhyay N
Year: 2001
Journal: J Cancer Res Clin Oncol
Title: Human cervical tumor cell (SiHa) surface alphavbeta3 integrin receptor has associated matrix metalloproteinase (MMP-2) activity.
Volume: 127
Issue: 11
Pages: 653-8
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Protein Domain
IPR015613 | TIMP2
Type: Family
Description: TIMP-2 is a serine protease inhibitor that inhibits MMPs. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19 []. As opposed to other TIMPs, TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. These effects require alpha 3 beta 1 integrin-mediated binding of TIMP-2 to endothelial cells. Further, TIMP-2 induces a decrease in total protein tyrosine phosphatase (PTP) activity associated with beta1 integrin subunits as well as dissociation of the phosphatase SHP-1 from beta1. TIMP-2 treatment also results in a concomitant increase in PTP activity associated with tyrosine kinase receptors FGFR-1 and KDR [].Tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of matrix metalloproteinases (MMPs) found in most tissues and body fluids. By inhibiting MMPs activities, they participate in tissue remodeling of the extracellular matrix (ECM). The balance between MMPs and TIMPs activities is involved in both normal and pathological events such as wound healing, tissue remodeling, angiogenesis, invasion, tumourigenesis and metastasis []. TIMPs also exhibit functions that appear to be independent of their metalloproteinase inhibitory capacity []. There are four mammalian TIMPs (TIMP-1 to -4), and each TIMP has its own profile of metalloproteinase inhibition.
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Publication
22438826 | J:183476
First Author: Jameson SA
Year: 2012
Journal: PLoS Genet
Title: Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad.
Volume: 8
Issue: 3
Pages: e1002575
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Allele
Gt(ROSA)26Sor<tm4(CAG-EYFP*,-tdTomato*,-KDR*,-mEYFP*,-Kdr*,-mKate2*)Ben> | MGI:6759810
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Rui Benedito
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
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Genotype
Genotype
Symbol: Aplnr/Aplnr Tg(Kdr-cre)#Brei/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
28757617 | J:249411
First Author: Hadzijusufovic E
Year: 2017
Journal: Leukemia
Title: Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site.
Volume: 31
Issue: 11
Pages: 2388-2397
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Publication
35314385 | J:322829
 
First Author: Taylor EL
Year: 2022
Journal: Bone
Title: GIRK3 deletion facilitates kappa opioid signaling in chondrocytes, delays vascularization and promotes bone lengthening in mice.
Volume: 159
Pages: 116391
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Publication
12107087 | J:77978
First Author: Shih SC
Year: 2002
Journal: Am J Pathol
Title: Molecular profiling of angiogenesis markers.
Volume: 161
Issue: 1
Pages: 35-41
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Publication
24048574 | J:204009
First Author: Winterhager E
Year: 2013
Journal: Biol Reprod
Title: Decidual angiogenesis and placental orientation are altered in mice heterozygous for a dominant loss-of-function Gja1 (connexin43) mutation.
Volume: 89
Issue: 5
Pages: 111
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Publication
34475534 | J:325307
First Author: Choi J
Year: 2021
Journal: Nat Cell Biol
Title: Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration.
Volume: 23
Issue: 9
Pages: 953-966
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Publication
35027734 | J:321043
First Author: Das A
Year: 2022
Journal: Nat Cell Biol
Title: Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis.
Volume: 24
Issue: 1
Pages: 35-50
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Publication
36512424 | J:336135
 
First Author: Tang X
Year: 2023
Journal: J Clin Invest
Title: Long noncoding RNA LEENE promotes angiogenesis and ischemic recovery in diabetes models.
Volume: 133
Issue: 3
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Publication
17462595 | J:121775
First Author: Narumiya H
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Endocardiogenesis in embryoid bodies: novel markers identified by gene expression profiling.
Volume: 357
Issue: 4
Pages: 896-902
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Publication
30024304 | J:265831
First Author: Good RJ
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: MicroRNA dysregulation in lung injury: the role of the miR-26a/EphA2 axis in regulation of endothelial permeability.
Volume: 315
Issue: 4
Pages: L584-L594
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Publication
30601675 | J:289121
First Author: Wang Y
Year: 2019
Journal: FASEB J
Title: High levels of HtrA4 detected in preeclamptic circulation may disrupt endothelial cell function by cleaving the main VEGFA receptor KDR.
Volume: 33
Issue: 4
Pages: 5058-5066
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Publication
30258227 | J:266626
First Author: Lorenz L
Year: 2018
Journal: Nature
Title: Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival.
Volume: 562
Issue: 7725
Pages: 128-132
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Publication
29026147 | J:256372
First Author: Nagao M
Year: 2017
Journal: Sci Rep
Title: Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis.
Volume: 7
Issue: 1
Pages: 13027
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Publication
36240771 | J:330969
     
First Author: Martins LF
Year: 2022
Journal: Neuron
Title: Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.
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Publication
25062690 | J:227456
First Author: Lathen C
Year: 2014
Journal: Circulation
Title: ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease.
Volume: 130
Issue: 14
Pages: 1179-91
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Allele
TgTn(pb-Gt(ROSA)26Sor/CAG-EYFP*,-tdTomato*,-KDR*,-mEYFP*,-Kdr*,-mKate2*)#Ben | MGI:6761550
Name: transgenic transposon concatemer, Rui Benedito
Allele Type: Transgenic
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence, Reporter, Transposon concatemer
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Genotype
Genotype
Symbol: Kdr/Kdr<+> Tg(tetO-Kdr*)4377.5Rwng/? Tg(Cebpb-tTA)5Bjd/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * NMRI
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Kdr-cre)15962Brei/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Kdr-cre)15964Brei/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
11221852 | J:68578
First Author: Hiratsuka S
Year: 2001
Journal: Cancer Res
Title: Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis.
Volume: 61
Issue: 3
Pages: 1207-13
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Publication
29342188 | J:258235
First Author: Deveza L
Year: 2018
Journal: PLoS One
Title: Comparative analysis of gene expression identifies distinct molecular signatures of bone marrow- and periosteal-skeletal stem/progenitor cells.
Volume: 13
Issue: 1
Pages: e0190909
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Publication
14745955 | J:88924
First Author: Licht AH
Year: 2004
Journal: Dev Dyn
Title: Endothelium-specific Cre recombinase activity in flk-1-Cre transgenic mice.
Volume: 229
Issue: 2
Pages: 312-8
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Publication
25912686 | J:239280
First Author: Poché RA
Year: 2015
Journal: Dev Biol
Title: Macrophages engulf endothelial cell membrane particles preceding pupillary membrane capillary regression.
Volume: 403
Issue: 1
Pages: 30-42
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Publication
22865640 | J:202652
First Author: Yang J
Year: 2012
Journal: Cardiovasc Res
Title: Inhibition of Notch2 by Numb/Numblike controls myocardial compaction in the heart.
Volume: 96
Issue: 2
Pages: 276-85
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Publication
27981571 | J:241898
First Author: Van Welden S
Year: 2017
Journal: J Pathol
Title: Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Volume: 241
Issue: 4
Pages: 547-558
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Protein
P25785
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Protein
Q8BSJ3
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Protein
Q6GXA8
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
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Protein
B1AQJ3
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: true
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Protein
Q6PI17
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Publication
15036259 | -
First Author: Lambert E
Year: 2004
Journal: Crit Rev Oncol Hematol
Title: TIMPs as multifacial proteins.
Volume: 49
Issue: 3
Pages: 187-98
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Publication
27031698 | J:249149
First Author: Huang W
Year: 2016
Journal: PLoS One
Title: Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.
Volume: 11
Issue: 3
Pages: e0152833
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Publication
24912173 | J:211622
First Author: DeFalco T
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis.
Volume: 111
Issue: 23
Pages: E2384-93
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Publication
37972594 | J:344401
First Author: Bhat GP
Year: 2024
Journal: Neuron
Title: Structured wound angiogenesis instructs mesenchymal barrier compartments in the regenerating nerve.
Volume: 112
Issue: 2
Pages: 209-229.e11
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Publication
28802047 | J:252386
First Author: Pontes-Quero S
Year: 2017
Journal: Cell
Title: Dual ifgMosaic: A Versatile Method for Multispectral and Combinatorial Mosaic Gene-Function Analysis.
Volume: 170
Issue: 4
Pages: 800-814.e18
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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