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Search results 1 to 100 out of 1779 for Dcc

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Type Details Score
Gene
1630 | DCC
Type: gene
Organism: human
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Gene
569360 | dcc
Type: gene
Organism: zebrafish
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Gene
693352 | DCC
Type: gene
Organism: macaque, rhesus
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Gene
100486082 | dcc
Type: gene
Organism: frog, western clawed
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Gene
25311 | Dcc
Type: gene
Organism: rat
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Gene
483976 | DCC
Type: gene
Organism: dog, domestic
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Gene
455425 | DCC
Type: gene
Organism: chimpanzee
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Gene
537176 | DCC
Type: gene
Organism: cattle
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Protein Domain
IPR033012 | DCC
Type: Family
Description: DCC (deleted in colorectal cancer) is a receptor for netrin required for axon guidance [, ]. It also binds a second axon guidance protein, Draxin []. The interactions between these guidance cues and DCC play a key role in the development of the nervous system.DCC belongs to the immunoglobulin superfamily. The protein consists of four N-terminal Ig-like domains []followed by six fibronectin type III domains (FN), a transmembrane segment and the cytosolic portion []. The deletion of DCC has been linked to the propensity of cancerous cells to metastasise [, ]. DCC indeed functions as a tumour suppressor through its ability to trigger tumour cell apoptosis [].
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Protein Coding Gene
MGI:94869 | Dcc
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22158121 | J:181517
First Author: Castets M
Year: 2011
Journal: Nature
Title: DCC constrains tumour progression via its dependence receptor activity.
Volume: 482
Issue: 7386
Pages: 534-7
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Publication
21957262 | J:176120
First Author: Ahmed G
Year: 2011
Journal: J Neurosci
Title: Draxin inhibits axonal outgrowth through the netrin receptor DCC.
Volume: 31
Issue: 39
Pages: 14018-23
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Publication
22358843 | J:181090
First Author: Krimpenfort P
Year: 2012
Journal: Nature
Title: Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours.
Volume: 482
Issue: 7386
Pages: 538-41
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Protein
P70211
Organism: Mus musculus/domesticus
Length: 1447  
Fragment?: false
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GXD Expression
GXD Expression
Probe: MGI:2670856
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7481908
Age: embryonic day 14.5
Image: 2B DCC
Note: Expression overlapping with CTIP2 (Bcl11b) expression.
Specimen Label: 2B DCC
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2670856
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7481908
Age: embryonic day 14.5
Image: 2B DCC
Note: Expression overlapping with CTIP2 (Bcl11b) expression.
Specimen Label: 2B DCC
Detected: true
Specimen Num: 1
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Publication
11239160 | -
First Author: Stein E
Year: 2001
Journal: Science
Title: Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation.
Volume: 291
Issue: 5510
Pages: 1976-82
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Publication
23038776 | -
First Author: Chen Q
Year: 2013
Journal: J Cell Sci
Title: N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors.
Volume: 126
Issue: Pt 1
Pages: 186-95
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Publication
8187090 | -
First Author: Miyake S
Year: 1994
Journal: Cancer Res
Title: Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis.
Volume: 54
Issue: 11
Pages: 3007-10
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GXD Expression
GXD Expression
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-05-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6158893
Age: embryonic day 15.5
Image: Dcc - E15.5
Note: There is particularly highly expression at early stages in developing neurons of the cortical plate and brainstem nuclei; expression subsequently tapers off with age.
Specimen Label: Dcc - E15.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3821385
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:3825941
Age: embryonic day 14.5
Image: Additional file 4 Dcc
Specimen Label: Additional file 4 Dcc
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-05-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6158893
Age: embryonic day 11.5
Image: Dcc - E11.5
Note: There is particularly highly expression at early stages in developing neurons of the cortical plate and brainstem nuclei; expression subsequently tapers off with age.
Specimen Label: Dcc - E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-05-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6158893
Age: embryonic day 13.5
Image: Dcc - E13.5
Note: There is particularly highly expression at early stages in developing neurons of the cortical plate and brainstem nuclei; expression subsequently tapers off with age.
Specimen Label: Dcc - E13.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-05-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6158893
Age: embryonic day 18.5
Image: Dcc - E18.5
Note: There is particularly highly expression at early stages in developing neurons of the cortical plate and brainstem nuclei; expression subsequently tapers off with age.
Specimen Label: Dcc - E18.5
Detected: true
Specimen Num: 4
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Publication
8861902 | -
First Author: Keino-Masu K
Year: 1996
Journal: Cell
Title: Deleted in Colorectal Cancer (DCC) encodes a netrin receptor.
Volume: 87
Issue: 2
Pages: 175-85
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Publication
26005129 | J:223929
First Author: Reynolds LM
Year: 2016
Journal: Behav Brain Res
Title: dcc Haploinsufficiency results in blunted sensitivity to cocaine enhancement of reward seeking.
Volume: 298
Issue: Pt A
Pages: 27-31
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Publication
21653843 | J:173458
First Author: Manitt C
Year: 2011
Journal: J Neurosci
Title: The netrin receptor DCC is required in the pubertal organization of mesocortical dopamine circuitry.
Volume: 31
Issue: 23
Pages: 8381-94
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Publication
28250456 | J:261685
First Author: Jamuar SS
Year: 2017
Journal: Nat Genet
Title: Biallelic mutations in human DCC cause developmental split-brain syndrome.
Volume: 49
Issue: 4
Pages: 606-612
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Publication
28108253 | J:243144
 
First Author: Pokinko M
Year: 2017
Journal: Neuroscience
Title: Dcc haploinsufficiency regulates dopamine receptor expression across postnatal lifespan.
Volume: 346
Pages: 182-189
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Publication
23291093 | J:196327
First Author: Horn KE
Year: 2013
Journal: Cell Rep
Title: DCC expression by neurons regulates synaptic plasticity in the adult brain.
Volume: 3
Issue: 1
Pages: 173-85
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Publication
24884839 | J:214366
 
First Author: Liang DY
Year: 2014
Journal: BMC Genomics
Title: The Netrin-1 receptor DCC is a regulator of maladaptive responses to chronic morphine administration.
Volume: 15
Pages: 345
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Publication
18585357 | J:143806
First Author: Ly A
Year: 2008
Journal: Cell
Title: DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1.
Volume: 133
Issue: 7
Pages: 1241-54
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Publication
28720317 | J:274512
First Author: Reynolds LM
Year: 2018
Journal: Biol Psychiatry
Title: DCC Receptors Drive Prefrontal Cortex Maturation by Determining Dopamine Axon Targeting in Adolescence.
Volume: 83
Issue: 2
Pages: 181-192
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Publication
27040640 | J:251343
 
First Author: Kim YJ
Year: 2016
Journal: Sci Rep
Title: Dcc Mediates Functional Assembly of Peripheral Auditory Circuits.
Volume: 6
Pages: 23799
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Publication
32264905 | J:316209
First Author: Glasgow SD
Year: 2020
Journal: Mol Brain
Title: Pre- and post-synaptic roles for DCC in memory consolidation in the adult mouse hippocampus.
Volume: 13
Issue: 1
Pages: 56
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Publication
24346136 | J:204130
 
First Author: Manitt C
Year: 2013
Journal: Transl Psychiatry
Title: dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.
Volume: 3
Pages: e338
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Publication
25031414 | J:215389
First Author: Bull SJ
Year: 2014
Journal: J Neurosci
Title: Progressive disorganization of paranodal junctions and compact myelin due to loss of DCC expression by oligodendrocytes.
Volume: 34
Issue: 29
Pages: 9768-78
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Publication
19788579 | J:155438
First Author: Grant A
Year: 2009
Journal: Eur J Neurosci
Title: Post-pubertal emergence of a dopamine phenotype in netrin-1 receptor-deficient mice.
Volume: 30
Issue: 7
Pages: 1318-28
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Publication
20345916 | J:160946
First Author: Yetnikoff L
Year: 2010
Journal: Eur J Neurosci
Title: Netrin-1 receptor in the ventral tegmental area is required for sensitization to amphetamine.
Volume: 31
Issue: 7
Pages: 1292-302
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Publication
25947198 | J:250817
First Author: Castillo-Paterna M
Year: 2015
Journal: EMBO Rep
Title: DCC functions as an accelerator of thalamocortical axonal growth downstream of spontaneous thalamic activity.
Volume: 16
Issue: 7
Pages: 851-62
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Publication
22521513 | J:185428
First Author: Rabe Bernhardt N
Year: 2012
Journal: Dev Biol
Title: DCC mediated axon guidance of spinal interneurons is essential for normal locomotor central pattern generator function.
Volume: 366
Issue: 2
Pages: 279-89
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Protein
Q3TZP5
Organism: Mus musculus/domesticus
Length: 1140  
Fragment?: true
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Publication
31806640 | J:285658
First Author: Boussouar A
Year: 2020
Journal: Cancer Res
Title: Netrin-1 and Its Receptor DCC Are Causally Implicated in Melanoma Progression.
Volume: 80
Issue: 4
Pages: 747-756
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Publication
35115383 | J:321810
 
First Author: Thiry L
Year: 2022
Journal: eNeuro
Title: Heterozygous Dcc Mutant Mice Have a Subtle Locomotor Phenotype.
Volume: 9
Issue: 2
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Publication
12451134 | J:80430
First Author: Finger JH
Year: 2002
Journal: J Neurosci
Title: The netrin 1 receptors Unc5h3 and Dcc are necessary at multiple choice points for the guidance of corticospinal tract axons.
Volume: 22
Issue: 23
Pages: 10346-56
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Publication
20875817 | J:166950
First Author: Shi M
Year: 2010
Journal: Dev Biol
Title: DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina.
Volume: 348
Issue: 1
Pages: 87-96
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Publication
29590626 | J:271537
First Author: Zhang JH
Year: 2018
Journal: Cell Rep
Title: DCC-Mediated Dab1 Phosphorylation Participates in the Multipolar-to-Bipolar Transition of Migrating Neurons.
Volume: 22
Issue: 13
Pages: 3598-3611
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Publication
12798294 | J:131673
First Author: Jiang Y
Year: 2003
Journal: Dev Biol
Title: Netrins and DCC in the guidance of migrating neural crest-derived cells in the developing bowel and pancreas.
Volume: 258
Issue: 2
Pages: 364-84
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Publication
18771734 | J:142435
First Author: Shi M
Year: 2008
Journal: Mol Cell Neurosci
Title: DCC is required for the tangential migration of noradrenergic neurons in locus coeruleus of mouse brain.
Volume: 39
Issue: 4
Pages: 529-38
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Publication
29712788 | J:265701
First Author: Vosberg DE
Year: 2018
Journal: J Neurosci
Title: Mesocorticolimbic Connectivity and Volumetric Alterations in DCC Mutation Carriers.
Volume: 38
Issue: 20
Pages: 4655-4665
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Publication
28341853 | J:271763
First Author: Welniarz Q
Year: 2017
Journal: Sci Rep
Title: Non cell-autonomous role of DCC in the guidance of the corticospinal tract at the midline.
Volume: 7
Issue: 1
Pages: 410
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Publication
33871356 | J:304719
   
First Author: Morcom L
Year: 2021
Journal: Elife
Title: DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation.
Volume: 10
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Publication
19409494 | J:154253
First Author: Marcos S
Year: 2009
Journal: Mol Cell Neurosci
Title: Differential roles of Netrin-1 and its receptor DCC in inferior olivary neuron migration.
Volume: 41
Issue: 4
Pages: 429-39
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Publication
9331350 | J:43652
First Author: Deiner MS
Year: 1997
Journal: Neuron
Title: Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia.
Volume: 19
Issue: 3
Pages: 575-89
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Publication
19141671 | J:144192
First Author: Rajasekharan S
Year: 2009
Journal: Development
Title: Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA.
Volume: 136
Issue: 3
Pages: 415-26
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Publication
18945908 | J:143795
First Author: Jarjour AA
Year: 2008
Journal: J Neurosci
Title: Maintenance of axo-oligodendroglial paranodal junctions requires DCC and netrin-1.
Volume: 28
Issue: 43
Pages: 11003-14
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Publication
32096760 | J:290253
   
First Author: Vigouroux RJ
Year: 2020
Journal: Elife
Title: Revisiting the role of Dcc in visual system development with a novel eye clearing method.
Volume: 9
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Publication
23738838 | J:227890
First Author: Auger ML
Year: 2013
Journal: Eur J Neurosci
Title: unc5c haploinsufficient phenotype: striking similarities with the dcc haploinsufficiency model.
Volume: 38
Issue: 6
Pages: 2853-63
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Publication
18691385 | J:142138
First Author: Bouchard JF
Year: 2008
Journal: J Neurochem
Title: Depolarization recruits DCC to the plasma membrane of embryonic cortical neurons and enhances axon extension in response to netrin-1.
Volume: 107
Issue: 2
Pages: 398-417
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GXD Expression
GXD Expression
   
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190099
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Dcc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190099
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Dcc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190099
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Dcc
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190099
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Dcc
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190099
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Dcc
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190099
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Dcc
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6170971
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190099
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Dcc
Detected: true
Specimen Num: 7
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Publication
28691197 | J:259672
First Author: Peng J
Year: 2018
Journal: Dev Dyn
Title: Loss of Dcc in the spinal cord is sufficient to cause a deficit in lateralized motor control and the switch to a hopping gait.
Volume: 247
Issue: 4
Pages: 620-629
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Publication
35118677 | J:340042
First Author: Lo PS
Year: 2022
Journal: J Neurochem
Title: The netrin-1 receptor DCC promotes the survival of a subpopulation of midbrain dopaminergic neurons: Relevance for ageing and Parkinson's disease.
Volume: 161
Issue: 3
Pages: 254-265
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Publication
28701345 | J:251090
First Author: Plooster M
Year: 2017
Journal: Mol Biol Cell
Title: TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching.
Volume: 28
Issue: 18
Pages: 2374-2385
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Publication
29386099 | J:271200
First Author: da Silva RV
Year: 2018
Journal: Cell Rep
Title: DCC Is Required for the Development of Nociceptive Topognosis in Mice and Humans.
Volume: 22
Issue: 5
Pages: 1105-1114
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Publication
15788454 | J:98501
First Author: Ding YQ
Year: 2005
Journal: Development
Title: Ventral migration of early-born neurons requires Dcc and is essential for the projections of primary afferents in the spinal cord.
Volume: 132
Issue: 9
Pages: 2047-56
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Publication
8570174 | J:30261
First Author: Cooper HM
Year: 1995
Journal: Oncogene
Title: Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo.
Volume: 11
Issue: 11
Pages: 2243-54
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Publication
22349703 | J:197279
First Author: Liu Y
Year: 2012
Journal: J Cell Sci
Title: Differential regulation of myosin X movements by its cargos, DCC and neogenin.
Volume: 125
Issue: Pt 3
Pages: 751-62
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Publication
24449837 | J:208339
First Author: Laumonnerie C
Year: 2014
Journal: Development
Title: Netrin 1 and Dcc signalling are required for confinement of central axons within the central nervous system.
Volume: 141
Issue: 3
Pages: 594-603
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Publication
27223328 | J:234106
   
First Author: Leggere JC
Year: 2016
Journal: Elife
Title: NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord.
Volume: 5
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Publication
32701653 | J:317467
First Author: Bourojeni FB
Year: 2021
Journal: Pain
Title: Netrin-1 receptor DCC is required for the contralateral topography of lamina I anterolateral system neurons.
Volume: 162
Issue: 1
Pages: 161-175
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Publication
12799072 | J:84360
First Author: Dalvin S
Year: 2003
Journal: Gene Expr Patterns
Title: Expression of Netrin-1 and its two receptors DCC and UNC5H2 in the developing mouse lung.
Volume: 3
Issue: 3
Pages: 279-83
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Publication
20434207 | J:167951
First Author: Tcherkezian J
Year: 2010
Journal: Cell
Title: Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation.
Volume: 141
Issue: 4
Pages: 632-44
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Publication
10843775 | J:62806
First Author: Gad JM
Year: 2000
Journal: Exp Eye Res
Title: The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina.
Volume: 70
Issue: 6
Pages: 711-22
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Publication
18005074 | J:130146
First Author: Grant A
Year: 2007
Journal: Eur J Neurosci
Title: Netrin-1 receptor-deficient mice show enhanced mesocortical dopamine transmission and blunted behavioural responses to amphetamine.
Volume: 26
Issue: 11
Pages: 3215-28
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Publication
23820928 | J:312040
First Author: Kim JH
Year: 2013
Journal: Psychopharmacology (Berl)
Title: Netrin-1 receptor-deficient mice show age-specific impairment in drug-induced locomotor hyperactivity but still self-administer methamphetamine.
Volume: 230
Issue: 4
Pages: 607-16
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Publication
15534618 | J:110129
First Author: Flores C
Year: 2005
Journal: Mol Psychiatry
Title: Netrin receptor deficient mice exhibit functional reorganization of dopaminergic systems and do not sensitize to amphetamine.
Volume: 10
Issue: 6
Pages: 606-12
•
•
•
•
•
Publication
16244667 | J:166022
First Author: Xie Y
Year: 2005
Journal: Nat Cell Biol
Title: Phosphatidylinositol transfer protein-alpha in netrin-1-induced PLC signalling and neurite outgrowth.
Volume: 7
Issue: 11
Pages: 1124-32
•
•
•
•
•
Publication
37149867 | J:336857
First Author: Dailey-Krempel B
Year: 2023
Journal: Cell Rep
Title: A tug of war between DCC and ROBO1 signaling during commissural axon guidance.
Volume: 42
Issue: 5
Pages: 112455
•
•
•
•
•
Publication
9441666 | J:45336
First Author: Gad JM
Year: 1997
Journal: Dev Biol
Title: The expression patterns of guidance receptors, DCC and Neogenin, are spatially and temporally distinct throughout mouse embryogenesis.
Volume: 192
Issue: 2
Pages: 258-73
•
•
•
•
•
Publication
24739528 | J:213245
 
First Author: Srivatsa S
Year: 2014
Journal: Nat Commun
Title: Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation.
Volume: 5
Pages: 3708
•
•
•
•
•
Publication
27539716 | J:311495
First Author: Salehi P
Year: 2016
Journal: J Assoc Res Otolaryngol
Title: Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice.
Volume: 17
Issue: 5
Pages: 417-31
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:27063
Assay Type: RNA in situ
Annotation Date: 2024-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915524
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7647248
Age: embryonic day 16.5
Note: Two distinct layers of DCC mRNA expressing E16.5 cells were observed in the central retina. The first in the retinal ganglion cell layer and presumptive amacrine cell layer.
Specimen Label: 3C/D
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:27063
Assay Type: RNA in situ
Annotation Date: 2024-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915724
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7647248
Age: embryonic day 16.5
Note: Two distinct layers of DCC mRNA expressing E16.5 cells were observed in the central retina. The second in the outer region of the outer nuclear layer.
Specimen Label: 3C/D
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:27063
Assay Type: RNA in situ
Annotation Date: 2024-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573924
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7647248
Age: embryonic day 16.5
Note: Two distinct layers of DCC mRNA expressing E16.5 cells were observed in the central retina. The first in the retinal ganglion cell layer and presumptive amacrine cell layer.
Specimen Label: 3C/D
Detected: true
Specimen Num: 5
•
•
•
•
•
Publication
17701984 | J:132524
First Author: Howell DM
Year: 2007
Journal: J Comp Neurol
Title: Molecular guidance cues necessary for axon pathfinding from the ventral cochlear nucleus.
Volume: 504
Issue: 5
Pages: 533-49
•
•
•
•
•
Publication
24928309 | J:234225
First Author: Bouhidel JO
Year: 2015
Journal: Biochim Biophys Acta
Title: Netrin-1 improves post-injury cardiac function in vivo via DCC/NO-dependent preservation of mitochondrial integrity, while attenuating autophagy.
Volume: 1852
Issue: 2
Pages: 277-89
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•
•
•
•
Publication
18033315 | J:130189
First Author: Shide K
Year: 2008
Journal: Leukemia
Title: Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F.
Volume: 22
Issue: 1
Pages: 87-95
•
•
•
•
•
Gene
9543 | IGDCC3
Type: gene
Organism: human
•
•
•
•
•
Gene
57722 | IGDCC4
Type: gene
Organism: human
•
•
•
•
•
Gene
343052 | LOC343052
Type: gene
Organism: human
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7647247
Assay Type: Immunohistochemistry
Annotation Date: 2024-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7647258
Age: embryonic day 15.5
Note: At the outer edge of the outer nuclear layer, cell bodies expressing significant levels of DCC protein were distributed sparsely. Overall, the level of DCC protein detected in the E15.5 outer nuclear layer was low.
Specimen Label: 5A
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
18796601 | J:142573
First Author: Furne C
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Netrin-1 is a survival factor during commissural neuron navigation.
Volume: 105
Issue: 38
Pages: 14465-70
•
•
•
•
•
Publication
34063230 | J:322061
 
First Author: Liu L
Year: 2021
Journal: Int J Mol Sci
Title: A Novel Netrin-1-Derived Peptide Enhances Protection against Neuronal Death and Mitigates of Intracerebral Hemorrhage in Mice.
Volume: 22
Issue: 9
•
•
•
•
•
Publication
15494733 | J:94375
First Author: Ren XR
Year: 2004
Journal: Nat Neurosci
Title: Focal adhesion kinase in netrin-1 signaling.
Volume: 7
Issue: 11
Pages: 1204-12
•
•
•
•
•




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