Type |
Details |
Score |
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
248
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
200
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
86
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
581
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
641
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
516
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Leidich SD |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis. |
Volume: |
271 |
Issue: |
44 |
Pages: |
27829-37 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Glycosylphosphatidylinositol (GPI) represents an important anchoring molecule for cell surface proteins. The first step in its synthesis is the transfer of N-acetylglucosamine (GlcNAc) from UDP-N-acetylglucosamine to phosphatidylinositol (PI). This chemically simple step is genetically complex because three or four genes are required in both Saccharomyces cerevisiae (GPI1, GPI2 and GPI3) and mammals (GPI1, PIG A, PIG H and PIG C), respectively [].This entry includes the mammalian Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (PigQ), its homologue Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1 (Gpi1) from yeast, and similar eukaryotic proteins. PigQ stabilises the complex of PIG-A, PIG-H, and PIG-C. It is important for the activity of this protein complex but not essential []. A similar function has been suggested for the yeast Gpi1 []. |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, translocation, chromosome aberration, radiation induced mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Fellmann N |
Year: |
1982 |
Journal: |
J Reprod Fertil |
Title: |
Pituitary-gonadal axis in sterile male mice heterozygous for autosomal reciprocal translocation T145H. |
Volume: |
66 |
Issue: |
2 |
Pages: |
723-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tiede A |
Year: |
1998 |
Journal: |
Biochem J |
Title: |
Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. |
Volume: |
334 ( Pt 3) |
|
Pages: |
609-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Finelli MJ |
Year: |
2019 |
Journal: |
Mol Neurobiol |
Title: |
Oxidation Resistance 1 Modulates Glycolytic Pathways in the Cerebellum via an Interaction with Glucose-6-Phosphate Isomerase. |
Volume: |
56 |
Issue: |
3 |
Pages: |
1558-1577 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lyon MF |
Year: |
1966 |
Journal: |
Cytogenetics |
Title: |
Autosomal translocations causing male sterility and viable aneuploidy in the mouse. |
Volume: |
5 |
Issue: |
5 |
Pages: |
335-54 |
|
•
•
•
•
•
|