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Search results 101 to 168 out of 168 for Ggh

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1624622
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Note: Expression was not detected in the digestive system.
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1646922
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736222
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1683322
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1700022
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1832122
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
•
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
•
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5310323
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423647
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EN387; Specimen N280
Detected: false
Specimen Num: 1
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Publication
24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Author
van den Akker GGH
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Allele
Ggh<em1Smoc> | MGI:7289865
Name: gamma-glutamyl hydrolase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7718070 | C57BL/6JSmoc-Ggh<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
30010080 | J:268703
 
First Author: de Kroon LMG
Year: 2018
Journal: Bone
Title: Identification of TGFβ-related genes regulated in murine osteoarthritis and chondrocyte hypertrophy by comparison of multiple microarray datasets.
Volume: 116
Pages: 67-77
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Publication
25775999 | J:222979
First Author: Hsieh YH
Year: 2015
Journal: J Pathol
Title: Hepatitis B virus pre-S2 mutant large surface protein inhibits DNA double-strand break repair and leads to genome instability in hepatocarcinogenesis.
Volume: 236
Issue: 3
Pages: 337-47
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Publication
10739875 | -
First Author: Galivan J
Year: 2000
Journal: Pharmacol Ther
Title: Glutamyl hydrolase. pharmacological role and enzymatic characterization.
Volume: 85
Issue: 3
Pages: 207-15
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Protein Domain
IPR015527 | Pept_C26_g-glut_hydrolase
Type: Family
Description: Gamma-glutamyl hydrolase (GH) is a lysosomal and secreted glycoprotein that hydrolyses the gamma-glutamyl tail of antifolate and folate polyglutamates. Tumour cells that have high levels of GH are inherently resistant to classical antifolates, and further resistance can be acquired by elevations in GH following exposure to this class of anti-tumour agents. The highest level of expression in normal tissues occurs in the liver and kidney in humans. GH is a low-affinity (micromolar), high-turnover enzyme that has a cysteine at the active site. GH is being evaluated as an intracellular target for inhibition in order to enhance the therapeutic activity of antifolates and fluorouracil [].The 3-dimensional structure of GH shows a central eight-stranded β-sheet, which is sandwiched by three and five α-helices on each side (see []. The fold resembles that of glutamine amidotransferases (GATase) of class I, which are characterised by a conserved Cys-His-Glu active site. The major differences consist of extensions in four loops and at the C terminus of GGH. The active site residues are well conserved and the catalytically essential cysteine, positioned at a nucleophile elbow, suggests that GGH is a cysteine peptidase.
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Protein
Q9Z0L8
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Protein
Q91XH7
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Protein
B9EKG3
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Publication
11953431 | -
First Author: Li H
Year: 2002
Journal: J Biol Chem
Title: Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate.
Volume: 277
Issue: 27
Pages: 24522-9
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