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Search results 1 to 100 out of 419 for Mus81

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Type Details Score
Gene
80198 | MUS81
Type: gene
Organism: human
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Gene
406839 | mus81
Type: gene
Organism: zebrafish
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Gene
715558 | MUS81
Type: gene
Organism: macaque, rhesus
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Gene
496413 | mus81
Type: gene
Organism: frog, western clawed
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Gene
293678 | Mus81
Type: gene
Organism: rat
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Gene
466667 | MUS81
Type: gene
Organism: chimpanzee
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Gene
476021 | MUS81
Type: gene
Organism: dog, domestic
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Gene
528432 | MUS81
Type: gene
Organism: cattle
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Protein Domain
IPR033309 | Mus81
Type: Family
Description: Budding yeast Mus81 complexes with Mms4 (EME1 or EME2 in humans) to form a structure-specific endonuclease that targets branched DNA structures with a 5'-end at the branch nick [, ]. Its typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions [, ].Similar to MUS81-EME1, human MUS81-EME2 cleaves 3'-flaps, replication forks and nicked Holliday junctions, and exhibits limited endonuclease activity with intact Holliday junctions. However, MUS81-EME2 can also cleave a variety of DNA structures including D-loop recombination intermediates and nicked duplex [, ].
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Protein Coding Gene
MGI:1918961 | Mus81
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15205536 | J:91570
First Author: McPherson JP
Year: 2004
Journal: Science
Title: Involvement of mammalian Mus81 in genome integrity and tumor suppression.
Volume: 304
Issue: 5678
Pages: 1822-6
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Publication
16107704 | J:100407
First Author: Dendouga N
Year: 2005
Journal: Mol Cell Biol
Title: Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis.
Volume: 25
Issue: 17
Pages: 7569-79
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Protein
A0A494BB15
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
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Publication
22551069 | -
First Author: Shin YK
Year: 2012
Journal: FEBS J
Title: Human MUS81 complexes stimulate flap endonuclease 1.
Volume: 279
Issue: 13
Pages: 2412-30
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Publication
11741546 | J:72909
First Author: Chen XB
Year: 2001
Journal: Mol Cell
Title: Human Mus81-associated endonuclease cleaves Holliday junctions in vitro.
Volume: 8
Issue: 5
Pages: 1117-27
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Protein
Q91ZJ0
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
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Protein
F8WIN9
Organism: Mus musculus/domesticus
Length: 502  
Fragment?: false
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Protein
F6VIY4
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: true
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Publication
26876210 | J:230810
First Author: Ghamrasni SE
Year: 2016
Journal: Oncogene
Title: Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation.
Volume: 35
Issue: 37
Pages: 4836-45
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Publication
17875692 | J:124877
First Author: Pamidi A
Year: 2007
Journal: Cancer Res
Title: Functional interplay of p53 and Mus81 in DNA damage responses and cancer.
Volume: 67
Issue: 18
Pages: 8527-35
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Publication
19026666 | J:144039
First Author: Tamblyn L
Year: 2009
Journal: Mutat Res
Title: A role for Mus81 in the repair of chromium-induced DNA damage.
Volume: 660
Issue: 1-2
Pages: 57-65
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Publication
24858046 | J:221273
First Author: El Ghamrasni S
Year: 2015
Journal: Oncogene
Title: Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression.
Volume: 34
Issue: 14
Pages: 1780-9
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Publication
25056314 | J:218118
First Author: Larin M
Year: 2014
Journal: Nucleic Acids Res
Title: Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair.
Volume: 42
Issue: 15
Pages: 9807-20
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Publication
17363897 | -
First Author: Gaskell LJ
Year: 2007
Journal: EMBO J
Title: Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?
Volume: 26
Issue: 7
Pages: 1891-901
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Publication
26273056 | -
First Author: Mayle R
Year: 2015
Journal: Science
Title: DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.
Volume: 349
Issue: 6249
Pages: 742-7
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Publication
21625617 | J:172721
First Author: El Ghamrasni S
Year: 2011
Journal: PLoS Genet
Title: Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.
Volume: 7
Issue: 5
Pages: e1001385
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Publication
21903938 | J:188824
First Author: Boon RA
Year: 2011
Journal: Circ Res
Title: MicroRNA-29 in aortic dilation: implications for aneurysm formation.
Volume: 109
Issue: 10
Pages: 1115-9
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Publication
23361013 | J:210130
 
First Author: Fugger K
Year: 2013
Journal: Nat Commun
Title: FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress.
Volume: 4
Pages: 1423
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Publication
36190107 | J:330401
   
First Author: Fernandez KC
Year: 2022
Journal: Elife
Title: The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes.
Volume: 11
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Publication
14642571 | -
First Author: Fu Y
Year: 2003
Journal: DNA Repair (Amst)
Title: Functional domains required for the Saccharomyces cerevisiae Mus81-Mms4 endonuclease complex formation and nuclear localization.
Volume: 2
Issue: 12
Pages: 1435-47
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Publication
24371268 | -
First Author: Pepe A
Year: 2014
Journal: Nucleic Acids Res
Title: Substrate specificity of the MUS81-EME2 structure selective endonuclease.
Volume: 42
Issue: 6
Pages: 3833-45
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Publication
24692662 | -
First Author: Amangyeld T
Year: 2014
Journal: Nucleic Acids Res
Title: Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex.
Volume: 42
Issue: 9
Pages: 5846-62
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Publication
21858106 | J:176364
First Author: Moltzer E
Year: 2011
Journal: PLoS One
Title: Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: effect of angiotensin II type 1 (AT1) receptor blockade.
Volume: 6
Issue: 8
Pages: e23411
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Publication
25255451 | J:222498
First Author: Ramnath NW
Year: 2014
Journal: PLoS One
Title: Extracellular matrix defects in aneurysmal Fibulin-4 mice predispose to lung emphysema.
Volume: 9
Issue: 9
Pages: e106054
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Publication
17293478 | J:133703
First Author: Hanada K
Year: 2007
Journal: Circ Res
Title: Perturbations of vascular homeostasis and aortic valve abnormalities in fibulin-4 deficient mice.
Volume: 100
Issue: 5
Pages: 738-46
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Publication
30844428 | J:294773
 
First Author: Burger J
Year: 2019
Journal: Cell Signal
Title: Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling.
Volume: 58
Pages: 65-78
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Publication
18413719 | J:320281
First Author: Chang JH
Year: 2008
Journal: Genes Dev
Title: Crystal structure of the Mus81-Eme1 complex.
Volume: 22
Issue: 8
Pages: 1093-106
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Protein Coding Gene
MGP_CAROLIEiJ_G0022554 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024650 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1918961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025124 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023917 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024417 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024544 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024511 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024630 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023663 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023979 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014051 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023468 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
29931197 | J:268373
First Author: van der Pluijm I
Year: 2018
Journal: Cardiovasc Res
Title: Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.
Volume: 114
Issue: 13
Pages: 1776-1793
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Publication
27585882 | J:277724
First Author: Bultmann-Mellin I
Year: 2016
Journal: Dis Model Mech
Title: Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice.
Volume: 9
Issue: 11
Pages: 1367-1374
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Publication
31019073 | J:275812
First Author: Previato de Almeida L
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Shugoshin protects centromere pairing and promotes segregation of nonexchange partner chromosomes in meiosis.
Volume: 116
Issue: 19
Pages: 9417-9422
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Publication
22579284 | J:222674
First Author: Vannier JB
Year: 2012
Journal: Cell
Title: RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity.
Volume: 149
Issue: 4
Pages: 795-806
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Publication
17289582 | J:320165
First Author: Ciccia A
Year: 2007
Journal: Mol Cell
Title: Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.
Volume: 25
Issue: 3
Pages: 331-43
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Publication
18692478 | J:140323
First Author: Mistry H
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Interplay between Np95 and Eme1 in the DNA damage response.
Volume: 375
Issue: 3
Pages: 321-5
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Publication
24076219 | J:204996
First Author: Castor D
Year: 2013
Journal: Mol Cell
Title: Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.
Volume: 52
Issue: 2
Pages: 221-33
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Publication
26980189 | J:232402
First Author: Thongthip S
Year: 2016
Journal: Genes Dev
Title: Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.
Volume: 30
Issue: 6
Pages: 645-59
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Publication
26443207 | J:227197
First Author: Jacome A
Year: 2015
Journal: EMBO J
Title: NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity.
Volume: 34
Issue: 21
Pages: 2604-19
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Publication
21240276 | J:168567
First Author: Crossan GP
Year: 2011
Journal: Nat Genet
Title: Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia.
Volume: 43
Issue: 2
Pages: 147-52
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom