This entry includes AIF1 (also know as Iba1, ionized calcium-binding adapter molecule 1) and AIF1L (Iba2) from humans. They are actin-binding proteins []. AIF1 has been shown to promote vascular smooth muscle cell migration []. AIF1L is involved in the stabilization of podocyte morphology by titrating actomyosin contractility and membrane dynamics [].This entry also includes calcium-binding protein B from Dictyostelium discoideum.
