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Search results 801 to 900 out of 5063 for Pole

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Type Details Score
Allele
Cspp1<Gt(IST14748A9)Tigm> | MGI:5254718
 
Name: centrosome and spindle pole associated protein 1; gene trap IST14748A9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cspp1<Gt(IST14874D2)Tigm> | MGI:5265908
 
Name: centrosome and spindle pole associated protein 1; gene trap IST14874D2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cspp1<Gt(IST14931C11)Tigm> | MGI:5270364
 
Name: centrosome and spindle pole associated protein 1; gene trap IST14931C11, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Cspp1<Gt(IST15039H4)Tigm> | MGI:5278393
 
Name: centrosome and spindle pole associated protein 1; gene trap IST15039H4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Strain
MGI:6117094 | C57BL/6NJ-Cspp1<em1(IMPC)J>/Mmjax
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Espl1/Espl1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Espl1/Espl1
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Espl1/Espl1
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cspp1/Cspp1
Background: C57BL/6NJ-Cspp1/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Protein Coding Gene
MGI:106544 | Spout1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2687282 | Cep104
Type: protein_coding_gene
Organism: mouse, laboratory
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GO Term
GO:1990047 | spindle matrix
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Publication
11827982 | -
First Author: Castillo AR
Year: 2002
Journal: J Cell Biol
Title: The yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p.
Volume: 156
Issue: 3
Pages: 453-65
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Publication
22535527 | -
First Author: Bergman ZJ
Year: 2012
Journal: Mol Biol Cell
Title: Constitutive dynein activity in She1 mutants reveals differences in microtubule attachment at the yeast spindle pole body.
Volume: 23
Issue: 12
Pages: 2319-26
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Allele
Pole<em3Ewht> | MGI:7797733
Name: polymerase (DNA directed), epsilon; endonuclease-mediated mutation 3, Eileen White
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
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CL Term
CL:0000579 | border follicle cell
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CL Term
CL:0007022 | micropylar cell
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Publication
11839787 | J:74515
First Author: Goldring K
Year: 2002
Journal: J Cell Sci
Title: The effect of galectin-1 on the differentiation of fibroblasts and myoblasts in vitro.
Volume: 115
Issue: Pt 2
Pages: 355-66
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GXD Expression
GXD Expression
 
Probe: MGI:7356292
Assay Type: RNA in situ
Annotation Date: 2022-10-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7367171
Age: embryonic day 18.5
Note: In this mutant the expressing region has also shifted to the caudal pole compared to wild-type.
Specimen Label: 10C'
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:7664035
Assay Type: RNA in situ
Annotation Date: 2024-07-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Graded
Stage: TS23
Assay Id: MGI:7664064
Age: embryonic day 15.5
Note: Transient expression in gradient-like distribution starting from rostral pole at E15 and spreading caudally.
Specimen Label: 3B2
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:1342330
Assay Type: Immunohistochemistry
Annotation Date: 2005-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3288320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3575639
Age: embryonic day 12.5
Note: Expression is at the basal pole of cells at the epithelial-mesenchymal border.
Specimen Label: Not Shown
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5588412
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268514
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:5588433
Age: embryonic day 9.0
Image: 3C,D,D'
Note: Expression was detected in the ventricular segment and in the venous pole of the heart tube.
Specimen Label: 3C,D,D'
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3836954
Assay Type: Immunohistochemistry
Annotation Date: 2009-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3837347
Age: embryonic day 16.5
Image: 4B
Note: Expression is in the posterior lens pole with the forming suture.
Specimen Label: 4B
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:3836956
Assay Type: Immunohistochemistry
Annotation Date: 2009-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3837348
Age: embryonic day 16.5
Image: 4D
Note: Expression is in the posterior lens pole with the forming suture.
Specimen Label: 4D
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:3836952
Assay Type: Immunohistochemistry
Annotation Date: 2009-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3837351
Age: embryonic day 16.5
Image: 4J
Note: Expression is in the posterior lens pole with the forming suture.
Specimen Label: 4J
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:3836950
Assay Type: Immunohistochemistry
Annotation Date: 2009-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3837350
Age: embryonic day 16.5
Image: 4H
Note: Expression is in the posterior lens pole with the forming suture.
Specimen Label: 4H
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:1342354
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3577822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6324340
Age: embryonic day 14.5
Image: 6D
Note: Decreased expression at basal pole of epithelial cells subjacent to the subepithelial basemembrane.
Specimen Label: 6D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6324278
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3577824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6324342
Age: embryonic day 16.5
Image: 6C
Note: Faint expression at basal pole of epithelial cells facing subepithelial basement membrane.
Specimen Label: 6C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6313376
Assay Type: RNA in situ
Annotation Date: 2019-06-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6313387
Age: embryonic day 10.5
Image: 2a E10.5
Note: Strong expression in optic cup, preponderantly in anterior pole of retina.
Specimen Label: 2a E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6313376
Assay Type: RNA in situ
Annotation Date: 2019-06-10
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1716819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6313387
Age: embryonic day 11.5
Image: 2a E11.5
Note: Authors report strongest expression of all stages analyzed, localized mostly in anterior pole of retina.
Specimen Label: 2a E11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3763819
Assay Type: RNA in situ
Annotation Date: 2011-12-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5297707
Age: embryonic day 6.5
Image: 6a/b
Note: Expression is present at the mesometrial pole of the deciduum in the mesometrial component.
Specimen Label: 6a/b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:32522
Assay Type: RNA in situ
Annotation Date: 2023-03-07
Strength: Present
Sex: Female
Emaps: EMAPS:3526928
Pattern: Graded
Stage: TS28
Assay Id: MGI:7442030
Age: postnatal adult
Image: 7C maternal
Note: Expression is in the antimesometrial pole and decreased gradually toward the mesometrial pole.
Specimen Label: 7C maternal
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:32522
Assay Type: RNA in situ
Annotation Date: 2023-03-07
Strength: Present
Sex: Female
Emaps: EMAPS:3526928
Pattern: Graded
Stage: TS28
Assay Id: MGI:7442030
Age: postnatal adult
Image: 7G maternal
Note: Expression is in the antimesometrial pole and decreased gradually toward the mesometrial pole.
Specimen Label: 7G maternal
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5633926
Assay Type: Immunohistochemistry
Annotation Date: 2015-04-28
Strength: Present
Sex: Male
Emaps: EMAPS:2910628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5633927
Age: postnatal adult
Image: 5B
Note: Expression is in the plasma membrane of the basal pole of Sertoli cells.
Specimen Label: 5B
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5633926
Assay Type: Immunohistochemistry
Annotation Date: 2015-04-28
Strength: Present
Sex: Male
Emaps: EMAPS:2910628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5633927
Age: postnatal adult
Image: 5A
Note: Expression is in the plasma membrane of the basal pole of Sertoli cells.
Specimen Label: 5A
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3590416
Assay Type: RNA in situ
Annotation Date: 2005-10-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1605811
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:3590493
Age: embryonic day 7.5
Image: 3A
Note: Expression is present exclusively within the visceral endoderm at the extra-embryonic pole of the embryo.
Specimen Label: 3A
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3604712
Assay Type: Immunohistochemistry
Annotation Date: 2005-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3604715
Age: embryonic day 13.5
Note: Expression is in a bundle in an area at the rostral pole of the cerebellum.
Specimen Label: 4F
Detected: true
Specimen Num: 30
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GXD Expression
GXD Expression
 
Probe: MGI:3604712
Assay Type: Immunohistochemistry
Annotation Date: 2005-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3604715
Age: embryonic day 13.5
Note: Expression is in a bundle in an area at the rostral pole of the cerebellum.
Specimen Label: 4G
Detected: true
Specimen Num: 31
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GXD Expression
GXD Expression
 
Probe: MGI:31382
Assay Type: RNA in situ
Annotation Date: 2010-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:4838635
Age: embryonic day 12.5
Note: The more ventral band also connects the olfactory bulb to the caudal pole of the telencephalon
Specimen Label: 3c
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:1927599
Assay Type: RNA in situ
Annotation Date: 2001-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1633815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1929929
Age: embryonic day 9.0-9.5
Image: 1E,F
Note: Expression is at the laterodorsal side of the posterior pole of the looping heart tube.
Specimen Label: 1E,F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3577967
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-05
Strength: Present
Sex: Male
Emaps: EMAPS:2909822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6514880
Age: embryonic day 14.5
Image: 6C
Note: In the posterior pole of the testis, testis cords were Amh-positive in the connection sites.
Specimen Label: 6C
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:5581441
Assay Type: RNA in situ
Annotation Date: 2014-09-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5581452
Age: embryonic day 8.5
Image: 2A
Note: Expression is in the venous pole of the forming heart tube.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5581442
Assay Type: RNA in situ
Annotation Date: 2014-09-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5581454
Age: embryonic day 8.5
Image: 2E
Note: Expression is in the venous pole of the forming heart tube.
Specimen Label: 2E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5581442
Assay Type: RNA in situ
Annotation Date: 2014-09-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5581454
Age: embryonic day 8.5
Image: S2A
Note: Expression is in the venous pole of the forming heart tube.
Specimen Label: S2A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5904366
Assay Type: Immunohistochemistry
Annotation Date: 2017-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610519
Pattern: Scattered
Stage: TS19
Assay Id: MGI:5904440
Age: embryonic day 11.5
Image: 1A
Note: Expressing cells are at the arterial and venous pole and in scattered positions subepicardially.
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5904366
Assay Type: Immunohistochemistry
Annotation Date: 2017-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5904440
Age: embryonic day 11.5
Image: 1C
Note: Expressing cells are at the arterial and venous pole and in scattered positions subepicardially.
Specimen Label: 1C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5904366
Assay Type: Immunohistochemistry
Annotation Date: 2017-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610519
Pattern: Scattered
Stage: TS19
Assay Id: MGI:5904440
Age: embryonic day 11.5
Image: 1D
Note: Expressing cells are at the arterial and venous pole and in scattered positions subepicardially.
Specimen Label: 1D
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5904366
Assay Type: Immunohistochemistry
Annotation Date: 2017-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5904440
Age: embryonic day 11.5
Image: 1F
Note: Expressing cells are at the arterial and venous pole and in scattered positions subepicardially.
Specimen Label: 1F
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4868259
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2800323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5540903
Age: embryonic day 15.5
Image: GUDMAP:9116
Note: weak expression in presumptive S1 segment of early proximal tubule at urinary pole of maturing nephrons
Specimen Label: GUDMAP:9116
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3577970
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-05
Strength: Present
Sex: Male
Emaps: EMAPS:3589919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5646130
Age: embryonic day 11.5
Image: 3A
Note: Expression was detected in Sertoli cell precursors in the center/anterior pole of the genital ridge.
Specimen Label: 3A
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5317435
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6514865
Age: embryonic day 11.75
Image: 1B
Note: Expression was detected in a cluster near the anterior pole of the testis.
Specimen Label: 1B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5700423
Assay Type: RNA in situ
Annotation Date: 2016-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3643815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:5700431
Age: embryonic day 9.5
Note: Expressed in mesenchyme abutting the myocardium at the venous pole of the heart.
Specimen Label: 2A E9.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:32522
Assay Type: RNA in situ
Annotation Date: 2023-03-07
Strength: Present
Sex: Female
Emaps: EMAPS:3527128
Pattern: Graded
Stage: TS28
Assay Id: MGI:7442030
Age: postnatal adult
Image: 7C maternal
Note: Expression is in the antimesometrial pole and decreased gradually toward the mesometrial pole.
Specimen Label: 7C maternal
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:32522
Assay Type: RNA in situ
Annotation Date: 2023-03-07
Strength: Present
Sex: Female
Emaps: EMAPS:3527128
Pattern: Graded
Stage: TS28
Assay Id: MGI:7442030
Age: postnatal adult
Image: 7G maternal
Note: Expression is in the antimesometrial pole and decreased gradually toward the mesometrial pole.
Specimen Label: 7G maternal
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5558929
Assay Type: Immunohistochemistry
Annotation Date: 2014-04-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1634619
Pattern: Single cells
Stage: TS19
Assay Id: MGI:5559017
Age: embryonic day 11.5
Image: 1a/b
Note: Expressed in a few cells on the arterial pole of the heart.
Specimen Label: 1a/b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7437843
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557627
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7437876
Age: postnatal day 1
Note: Expression is in the odontoblast process and in the apical pole of the odontoblast cells.
Specimen Label: 2B
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5582733
Assay Type: Immunohistochemistry
Annotation Date: 2014-09-19
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5583026
Age: embryonic day 11.5
Image: 3B left
Note: Expressed similarly at the center and at the pole of the gonad.
Specimen Label: 3B left
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5582733
Assay Type: Immunohistochemistry
Annotation Date: 2014-09-19
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5583026
Age: embryonic day 11.5
Image: 3B right
Note: Expressed similarly at the center and at the pole of the gonad.
Specimen Label: 3B right
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:9165
Assay Type: RNA in situ
Annotation Date: 2017-06-20
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5902993
Age: embryonic day 11.5
Image: 1F
Note: Expression decreases at the anterior pole and remains strong at the posterior pole.
Specimen Label: 1F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:9165
Assay Type: RNA in situ
Annotation Date: 2017-06-20
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5902993
Age: embryonic day 11.5
Image: 1G
Note: Expression decreases at the anterior pole and remains strong at the posterior pole.
Specimen Label: 1G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:3039022
Assay Type: RNA in situ
Annotation Date: 2013-12-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5526017
Age: embryonic day 14.5
Image: 6C/F
Note: Expressed in the splanchnic mesoderm at the level of the venous pole of the heart.
Specimen Label: 6C/F
Detected: true
Specimen Num: 11
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Publication
26858254 | J:232725
First Author: Liu YJ
Year: 2016
Journal: J Biol Chem
Title: Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway.
Volume: 291
Issue: 14
Pages: 7426-38
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Publication
31704793 | J:292837
 
First Author: Li J
Year: 2019
Journal: Development
Title: The cyclin B2/CDK1 complex inhibits separase activity in mouse oocyte meiosis I.
Volume: 146
Issue: 23
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Publication
19625504 | J:153148
First Author: Kudo NR
Year: 2009
Journal: J Cell Sci
Title: Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I.
Volume: 122
Issue: Pt 15
Pages: 2686-98
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Allele
Ccl2<tm1Rol> | MGI:2175911
Name: C-C motif chemokine ligand 2; targeted mutation 1, Barrett J Rollins
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ppargc1a<tm1Brsp> | MGI:3511352
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha; targeted mutation 1, Bruce M Spiegelman
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Efemp1<tm1Lmar> | MGI:3770755
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 1; targeted mutation 1, Lihua Y Marmorstein
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Efemp1<tm1Eap> | MGI:3774265
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 1; targeted mutation 1, Eric A Pierce
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Cd46<tm1Atk> | MGI:5586970
Name: CD46 antigen, complement regulatory protein; targeted mutation 1, John P Atkinson
Allele Type: Targeted
Attribute String: Null/knockout
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Gene
7867 | MAPKAPK3
Type: gene
Organism: human
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Gene
2202 | EFEMP1
Type: gene
Organism: human
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GO Term
GO:1990942 | mitotic metaphase chromosome recapture
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Protein Coding Gene
MGI:3525111 | Cep44
Type: protein_coding_gene
Organism: mouse, laboratory
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Strain
MGI:5285749 | B6.129-Trp53<tm1Tyj> Espl1<Gt(XL058)Byg>
Attribute String: gene trap, mutant strain, targeted mutation, congenic
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Genotype
Genotype
Symbol: Espl1/Espl1 Tg(Mx1-cre)1Cgn/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Espl1/Espl1<+>
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Espl1/Espl1<+>
Background: B6.129P2-Espl1
Zygosity: ht
Has Mutant Allele: true
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Protein Coding Gene
MGI:1913692 | Spc25
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109327 | Bnip2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914915 | Dctn4
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Protein Coding Gene
MGI:1917716 | Ckap2l
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Protein Coding Gene
MGI:1921097 | Fam110a
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Protein Coding Gene
MGI:1913552 | Rmdn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1919218 | Wdr73
Type: protein_coding_gene
Organism: mouse, laboratory
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MP Term
MP:0008815 | anterior staphyloma
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Protein Coding Gene
MGI:1915303 | Ubxn2b
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
14561405 | J:86169
First Author: Terret ME
Year: 2003
Journal: Curr Biol
Title: The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity.
Volume: 13
Issue: 20
Pages: 1797-802
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Publication
9635188 | -
First Author: Eng K
Year: 1998
Journal: Curr Biol
Title: Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body.
Volume: 8
Issue: 11
Pages: 611-21
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Publication
7628693 | -
First Author: Nabeshima K
Year: 1995
Journal: Genes Dev
Title: p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites.
Volume: 9
Issue: 13
Pages: 1572-85
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GO Term
GO:0008275 | gamma-tubulin small complex
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Protein Coding Gene
MGI:1891749 | Wrap73
Type: protein_coding_gene
Organism: mouse, laboratory
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Strain
MGI:7797732 | C57BL/6J-Pole<em2Ewht>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7797734 | C57BL/6J-Pole<em3Ewht>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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GXD Expression
GXD Expression
 
Probe: MGI:7356276
Assay Type: RNA in situ
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270423
Pattern: Graded
Stage: TS23
Assay Id: MGI:7367163
Age: embryonic day 15.5
Note: In this mutant the expression area was reduced and had shifted towards the caudal pole of cortex.
Specimen Label: 3B'
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3759599
Assay Type: RNA in situ
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3759612
Age: embryonic day 13.0
Image: 2C
Note: Expression is in the distal pole of the S-shaped body with a slight extension into the vascular cleft.
Specimen Label: 2C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3759599
Assay Type: RNA in situ
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:3759612
Age: embryonic day 13.0
Note: Expression is in the distal pole of the S-shaped body with a slight extension into the vascular cleft.
Specimen Label: 2D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5506575
Assay Type: Immunohistochemistry
Annotation Date: 2013-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Not Specified
Stage: TS05
Assay Id: MGI:5506576
Age: embryonic day 4.0
Image: 2c
Note: Staining is intense at the apical pole of the external cells in about half the embryos examined.
Specimen Label: 2c
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1340548
Assay Type: Immunohistochemistry
Annotation Date: 2018-12-11
Strength: Present
Sex: Female
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6259754
Age: postnatal adult
Note: Expression in cords of cells at the mesometrial pole projectiong towards the embryo. Expression also at the antimesometrial pole.
Specimen Label: 5E
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1340548
Assay Type: Immunohistochemistry
Annotation Date: 2018-12-11
Strength: Present
Sex: Female
Emaps: EMAPS:3526928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6259754
Age: postnatal adult
Note: Expression in cords of cells at the mesometrial pole projectiong towards the embryo. Expression also at the antimesometrial pole.
Specimen Label: 5F
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5695259
Assay Type: Immunohistochemistry
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1907822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5695260
Age: embryonic day 14.0
Image: 5B E14
Note: Expression is in the lateral intercellular epithelial membranes and at the basal pole of epithelial cells at the mesenchymal interface.
Specimen Label: 5B E14
Detected: true
Specimen Num: 1
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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