|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 701 to 760 out of 760 for Ncam2

<< First    < Previous  |  Next >    Last >>
0.04s

Categories

Hits by Strain

Hits by Category

Type Details Score
Publication
28899917 | J:253021
First Author: William CM
Year: 2017
Journal: J Neurosci
Title: Activity-Dependent Dysfunction in Visual and Olfactory Sensory Systems in Mouse Models of Down Syndrome.
Volume: 37
Issue: 41
Pages: 9880-9888
•
•
•
•
•
Publication
24788405 | J:294518
First Author: Starbuck JM
Year: 2014
Journal: Am J Med Genet A
Title: Overlapping trisomies for human chromosome 21 orthologs produce similar effects on skull and brain morphology of Dp(16)1Yey and Ts65Dn mice.
Volume: 164A
Issue: 8
Pages: 1981-1990
•
•
•
•
•
Publication
17431903 | J:294519
First Author: Aldridge K
Year: 2007
Journal: Am J Med Genet A
Title: Differential effects of trisomy on brain shape and volume in related aneuploid mouse models.
Volume: 143A
Issue: 10
Pages: 1060-70
•
•
•
•
•
Publication
19844572 | J:154042
First Author: Noll C
Year: 2009
Journal: PLoS One
Title: DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase.
Volume: 4
Issue: 10
Pages: e7540
•
•
•
•
•
Publication
23201095 | J:196979
 
First Author: Kida E
Year: 2013
Journal: Exp Neurol
Title: Long-term running alleviates some behavioral and molecular abnormalities in Down syndrome mouse model Ts65Dn.
Volume: 240
Pages: 178-89
•
•
•
•
•
Publication
18172498 | J:131046
First Author: Sussan TE
Year: 2008
Journal: Nature
Title: Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome.
Volume: 451
Issue: 7174
Pages: 73-5
•
•
•
•
•
Publication
20368182 | J:167886
First Author: Salehi A
Year: 2009
Journal: Sci Transl Med
Title: Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome.
Volume: 1
Issue: 7
Pages: 7ra17
•
•
•
•
•
Publication
17901249 | J:130041
First Author: Kirsammer G
Year: 2008
Journal: Blood
Title: Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome.
Volume: 111
Issue: 2
Pages: 767-75
•
•
•
•
•
Publication
31043483 | J:277174
First Author: Jiang Y
Year: 2019
Journal: J Neurosci
Title: Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99).
Volume: 39
Issue: 27
Pages: 5255-5268
•
•
•
•
•
Publication
23124096 | J:196990
 
First Author: Hijazi M
Year: 2013
Journal: Exp Neurol
Title: Overexpression of DYRK1A inhibits choline acetyltransferase induction by oleic acid in cellular models of Down syndrome.
Volume: 239
Pages: 229-34
•
•
•
•
•
Publication
21467166 | J:171978
First Author: Yang A
Year: 2011
Journal: Cancer Res
Title: Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome.
Volume: 71
Issue: 10
Pages: 3573-81
•
•
•
•
•
Publication
16432181 | J:105996
First Author: Roper RJ
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice.
Volume: 103
Issue: 5
Pages: 1452-6
•
•
•
•
•
Publication
29716957 | J:277232
 
First Author: Aziz NM
Year: 2018
Journal: Dis Model Mech
Title: Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome.
Volume: 11
Issue: 6
•
•
•
•
•
Publication
11840489 | J:73800
First Author: Richtsmeier JT
Year: 2002
Journal: Am J Med Genet
Title: Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome.
Volume: 107
Issue: 4
Pages: 317-24
•
•
•
•
•
Publication
21490218 | J:170968
First Author: Blank M
Year: 2011
Journal: J Neurosci
Title: The Down syndrome critical region regulates retinogeniculate refinement.
Volume: 31
Issue: 15
Pages: 5764-76
•
•
•
•
•
Publication
24932939 | J:218355
 
First Author: Ash JA
Year: 2014
Journal: Neurobiol Dis
Title: Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice.
Volume: 70
Pages: 32-42
•
•
•
•
•
Publication
15499018 | J:93223
First Author: Olson LE
Year: 2004
Journal: Science
Title: A chromosome 21 critical region does not cause specific Down syndrome phenotypes.
Volume: 306
Issue: 5696
Pages: 687-90
•
•
•
•
•
Publication
28342823 | J:260938
 
First Author: Kleschevnikov AM
Year: 2017
Journal: Neurobiol Dis
Title: Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome.
Volume: 103
Pages: 1-10
•
•
•
•
•
Publication
19125866 | J:151137
First Author: Siddiqui A
Year: 2008
Journal: Genes Brain Behav
Title: Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801.
Volume: 7
Issue: 7
Pages: 810-20
•
•
•
•
•
Publication
30115750 | J:278768
 
First Author: Nguyen TL
Year: 2018
Journal: Dis Model Mech
Title: Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A.
Volume: 11
Issue: 9
•
•
•
•
•
Publication
24747640 | J:212324
First Author: Lane AA
Year: 2014
Journal: Nat Genet
Title: Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.
Volume: 46
Issue: 6
Pages: 618-23
•
•
•
•
•
Publication
26509735 | J:229168
First Author: Singh N
Year: 2016
Journal: Dev Dyn
Title: Chronic up-regulation of sonic hedgehog has little effect on postnatal craniofacial morphology of euploid and trisomic mice.
Volume: 245
Issue: 2
Pages: 114-22
•
•
•
•
•
Publication
15188443 | J:91221
First Author: Olson LE
Year: 2004
Journal: Dev Dyn
Title: Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes.
Volume: 230
Issue: 3
Pages: 581-9
•
•
•
•
•
Publication
33693642 | J:339533
First Author: Duchon A
Year: 2021
Journal: Hum Mol Genet
Title: Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models.
Volume: 30
Issue: 9
Pages: 771-788
•
•
•
•
•
Publication
38544574 | J:346702
First Author: Colombi I
Year: 2024
Journal: iScience
Title: Heterogeneous subpopulations of GABA(A)R-responding neurons coexist across neuronal network scales and developmental stages in health and disease.
Volume: 27
Issue: 4
Pages: 109438
•
•
•
•
•
Publication
28993310 | J:245580
First Author: Herault Y
Year: 2017
Journal: Dis Model Mech
Title: Rodent models in Down syndrome research: impact and future opportunities.
Volume: 10
Issue: 10
Pages: 1165-1186
•
•
•
•
•
Genotype
Genotype
Symbol: Ts(17<16>)65Dn/? Del(16Cbr1-Fam3b)1Rhr/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tbx5/Tbx5<+> Ts(17<16>)65Dn/?
Background: involves: C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Brwd1/Brwd1<+> Ts(17<16>)65Dn/?
Background: involves: C3H/HeJ * C57BL/6J * DBA/2J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Del(17Scaf8-Pde10a)2Yey/+ Ts(17<16>)65Dn/?
Background: involves: 129S7/SvEvBrd * DBA/2J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
24025767 | J:206099
First Author: Adorno M
Year: 2013
Journal: Nature
Title: Usp16 contributes to somatic stem-cell defects in Down's syndrome.
Volume: 501
Issue: 7467
Pages: 380-4
•
•
•
•
•
Publication
22293606 | J:182294
First Author: Guedj F
Year: 2012
Journal: Neurobiol Dis
Title: DYRK1A: a master regulatory protein controlling brain growth.
Volume: 46
Issue: 1
Pages: 190-203
•
•
•
•
•
Publication
23512985 | J:198546
First Author: Laguna A
Year: 2013
Journal: Hum Mol Genet
Title: Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome.
Volume: 22
Issue: 14
Pages: 2775-84
•
•
•
•
•
Publication
37714307 | J:341241
 
First Author: Lisgaras CP
Year: 2023
Journal: Neurobiol Dis
Title: Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by the medial septum.
Volume: 187
Pages: 106294
•
•
•
•
•
Publication
18629032 | J:208905
First Author: Forejt J
Year: 2003
Journal: Comp Funct Genomics
Title: Segmental trisomy of mouse chromosome 17: introducing an alternative model of Down's syndrome.
Volume: 4
Issue: 6
Pages: 647-52
•
•
•
•
•
Publication
17897742 | J:128743
First Author: Rachidi M
Year: 2007
Journal: Neurosci Res
Title: Mental retardation in Down syndrome: from gene dosage imbalance to molecular and cellular mechanisms.
Volume: 59
Issue: 4
Pages: 349-69
•
•
•
•
•
Publication
24801365 | J:214001
 
First Author: Souchet B
Year: 2014
Journal: Neurobiol Dis
Title: Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.
Volume: 69
Pages: 65-75
•
•
•
•
•
Publication
27029737 | J:242434
First Author: Li H
Year: 2016
Journal: Genetics
Title: Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier.
Volume: 203
Issue: 2
Pages: 763-70
•
•
•
•
•
Publication
17050550 | J:117029
First Author: Davisson M
Year: 2007
Journal: Hum Reprod
Title: Impact of trisomy on fertility and meiosis in male mice.
Volume: 22
Issue: 2
Pages: 468-76
•
•
•
•
•
Publication
36868208 | J:340242
First Author: Gao Y
Year: 2023
Journal: Cell
Title: β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function.
Volume: 186
Issue: 5
Pages: 1026-1038.e20
•
•
•
•
•
Publication
36042312 | J:336210
First Author: Caldwell ALM
Year: 2022
Journal: Nat Neurosci
Title: Aberrant astrocyte protein secretion contributes to altered neuronal development in multiple models of neurodevelopmental disorders.
Volume: 25
Issue: 9
Pages: 1163-1178
•
•
•
•
•
Publication
32783810 | J:298653
   
First Author: Zorrilla de San Martin J
Year: 2020
Journal: Elife
Title: Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse model of Down syndrome.
Volume: 9
•
•
•
•
•
Publication
31727829 | J:281685
First Author: Zhu PJ
Year: 2019
Journal: Science
Title: Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome.
Volume: 366
Issue: 6467
Pages: 843-849
•
•
•
•
•
Publication
19297404 | J:156661
First Author: Wiseman FK
Year: 2009
Journal: Hum Mol Genet
Title: Down syndrome--recent progress and future prospects.
Volume: 18
Issue: R1
Pages: R75-83
•
•
•
•
•
Publication
26209650 | J:239795
First Author: Fedoriw AM
Year: 2015
Journal: Development
Title: Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes.
Volume: 142
Issue: 17
Pages: 2972-80
•
•
•
•
•
Publication
27195491 | J:231889
First Author: Peiris H
Year: 2016
Journal: PLoS Genet
Title: A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.
Volume: 12
Issue: 5
Pages: e1006033
•
•
•
•
•
Publication
19625522 | J:151795
First Author: Peng S
Year: 2009
Journal: J Neurosci
Title: Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.
Volume: 29
Issue: 29
Pages: 9321-9
•
•
•
•
•
Publication
30998504 | J:284087
   
First Author: Schill EM
Year: 2019
Journal: JCI Insight
Title: Down syndrome mouse models have an abnormal enteric nervous system.
Volume: 5
•
•
•
•
•
Publication
24068166 | J:201811
First Author: Bhutta MF
Year: 2013
Journal: Mamm Genome
Title: Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media.
Volume: 24
Issue: 11-12
Pages: 439-45
•
•
•
•
•
Publication
22693452 | J:185269
First Author: Raveau M
Year: 2012
Journal: PLoS Genet
Title: The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.
Volume: 8
Issue: 5
Pages: e1002724
•
•
•
•
•
Publication
37014740 | J:337878
First Author: Xing Z
Year: 2023
Journal: Hum Mol Genet
Title: Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome.
Volume: 32
Issue: 13
Pages: 2205-2218
•
•
•
•
•
Publication
30504774 | J:268139
First Author: Adorno M
Year: 2018
Journal: Sci Rep
Title: Usp16 modulates Wnt signaling in primary tissues through Cdkn2a regulation.
Volume: 8
Issue: 1
Pages: 17506
•
•
•
•
•
Publication
37079499 | J:344996
First Author: Liu H
Year: 2023
Journal: PLoS Biol
Title: DSCAM gene triplication causes excessive GABAergic synapses in the neocortex in Down syndrome mouse models.
Volume: 21
Issue: 4
Pages: e3002078
•
•
•
•
•
Publication
34399854 | J:310473
First Author: Gao FJ
Year: 2021
Journal: Acta Neuropathol Commun
Title: Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates.
Volume: 9
Issue: 1
Pages: 137
•
•
•
•
•
Publication
19041304 | J:174270
First Author: Levine S
Year: 2009
Journal: Exp Mol Pathol
Title: Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease.
Volume: 86
Issue: 1
Pages: 18-22
•
•
•
•
•
Publication
35021077 | J:321505
First Author: Sheppard K
Year: 2022
Journal: Cell Rep
Title: Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation.
Volume: 38
Issue: 2
Pages: 110231
•
•
•
•
•
Publication
22126738 | J:196862
First Author: Zhang L
Year: 2012
Journal: Bioeng Bugs
Title: Genetic analysis of Down syndrome facilitated by mouse chromosome engineering.
Volume: 3
Issue: 1
Pages: 8-12
•
•
•
•
•
Publication
27538963 | J:242664
First Author: Gupta M
Year: 2016
Journal: Mamm Genome
Title: Mouse models of Down syndrome: gene content and consequences.
Volume: 27
Issue: 11-12
Pages: 538-555
•
•
•
•
•
Publication
16815330 | J:122937
First Author: Salehi A
Year: 2006
Journal: Neuron
Title: Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.
Volume: 51
Issue: 1
Pages: 29-42
•
•
•
•
•
Publication
28204906 | J:346590
First Author: Roubertoux PL
Year: 2017
Journal: Behav Genet
Title: Differential Brain, Cognitive and Motor Profiles Associated with Partial Trisomy. Modeling Down Syndrome in Mice.
Volume: 47
Issue: 3
Pages: 305-322
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom