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Search results 1 to 100 out of 114 for Slc7a11

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Type Details Score
Publication
16037214 | J:100476
First Author: Chintala S
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells.
Volume: 102
Issue: 31
Pages: 10964-9
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Publication
35614212 | J:330600
First Author: Maschalidi S
Year: 2022
Journal: Nature
Title: Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.
Volume: 606
Issue: 7915
Pages: 776-784
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Publication
24548853 | J:208250
 
First Author: McCullagh EA
Year: 2014
Journal: Behav Brain Res
Title: Behavioral characterization of system xc- mutant mice.
Volume: 265
Pages: 1-11
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Publication
35398053 | J:324717
 
First Author: Liu Z
Year: 2022
Journal: Mol Cell Endocrinol
Title: The solute carrier family 7 member 11 (SLC7A11) is regulated by LH/androgen and required for cystine/glutathione homeostasis in mouse Sertoli cells.
Volume: 549
Pages: 111641
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Publication
36417872 | J:344160
First Author: Aloi MS
Year: 2022
Journal: Cell Rep
Title: Loss of functional System x-c uncouples aberrant postnatal neurogenesis from epileptogenesis in the hippocampus of Kcna1-KO mice.
Volume: 41
Issue: 8
Pages: 111696
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Publication
37649973 | J:340513
 
First Author: Frare C
Year: 2023
Journal: Front Behav Neurosci
Title: Sex- and age-dependent contribution of System x(c)(-) to cognitive, sensory, and social behaviors revealed by comprehensive behavioral analyses of System x(c)(-) null mice.
Volume: 17
Pages: 1238349
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Publication
25799988 | J:220466
First Author: Jiang L
Year: 2015
Journal: Nature
Title: Ferroptosis as a p53-mediated activity during tumour suppression.
Volume: 520
Issue: 7545
Pages: 57-62
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Publication
19715555 | J:157811
First Author: Gnana-Prakasam JP
Year: 2009
Journal: Biochem J
Title: Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger.
Volume: 424
Issue: 2
Pages: 243-52
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Publication
10206947 | J:54626
First Author: Sato H
Year: 1999
Journal: J Biol Chem
Title: Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins.
Volume: 274
Issue: 17
Pages: 11455-8
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Publication
17963724 | J:128443
First Author: Liu RR
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Differential regulation of cell proliferation in neurogenic zones in mice lacking cystine transport by xCT.
Volume: 364
Issue: 3
Pages: 528-33
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Publication
17035536 | J:113249
First Author: Shih AY
Year: 2006
Journal: J Neurosci
Title: Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation.
Volume: 26
Issue: 41
Pages: 10514-23
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Publication
25036707 | J:215616
First Author: Soria FN
Year: 2014
Journal: J Clin Invest
Title: Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damage.
Volume: 124
Issue: 8
Pages: 3645-55
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Publication
33199267 | J:307540
 
First Author: Sosnoski HM
Year: 2020
Journal: Neurochem Int
Title: Sexually dimorphic and brain region-specific transporter adaptations in system xc- null mice.
Volume: 141
Pages: 104888
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Publication
20308543 | J:159323
First Author: Nabeyama A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: xCT deficiency accelerates chemically induced tumorigenesis.
Volume: 107
Issue: 14
Pages: 6436-41
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Publication
16144837 | J:102902
First Author: Sato H
Year: 2005
Journal: J Biol Chem
Title: Redox imbalance in cystine/glutamate transporter-deficient mice.
Volume: 280
Issue: 45
Pages: 37423-9
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Publication
27129162 | J:311045
First Author: Cai Y
Year: 2016
Journal: Oncotarget
Title: xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation.
Volume: 7
Issue: 21
Pages: 31001-13
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Publication
21191088 | J:170726
First Author: Massie A
Year: 2011
Journal: FASEB J
Title: Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.
Volume: 25
Issue: 4
Pages: 1359-69
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Publication
17200146 | J:121453
First Author: Sakakura Y
Year: 2007
Journal: J Leukoc Biol
Title: Expression and function of cystine/glutamate transporter in neutrophils.
Volume: 81
Issue: 4
Pages: 974-82
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Publication
34156426 | J:331134
First Author: Martis RM
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Early Onset of Age-Related Cataracts in Cystine/Glutamate Antiporter Knockout Mice.
Volume: 62
Issue: 7
Pages: 23
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Publication
29079265 | J:260963
First Author: Lee J
Year: 2017
Journal: Exp Cell Res
Title: The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production.
Volume: 361
Issue: 1
Pages: 178-191
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Publication
21490221 | J:170967
First Author: De Bundel D
Year: 2011
Journal: J Neurosci
Title: Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility.
Volume: 31
Issue: 15
Pages: 5792-803
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Publication
28086920 | J:272775
First Author: Merckx E
Year: 2017
Journal: J Neuroinflammation
Title: Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.
Volume: 14
Issue: 1
Pages: 9
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Publication
34108554 | J:323696
First Author: Sprimont L
Year: 2021
Journal: Sci Rep
Title: Cystine-glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice.
Volume: 11
Issue: 1
Pages: 12227
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Publication
31022385 | J:279785
 
First Author: Loewen JL
Year: 2019
Journal: Exp Neurol
Title: Genetic and pharmacological manipulation of glial glutamate transporters does not alter infection-induced seizure activity.
Volume: 318
Pages: 50-60
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Publication
31071489 | J:295231
First Author: Meyer AR
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: Cystine/Glutamate Antiporter (xCT) Is Required for Chief Cell Plasticity After Gastric Injury.
Volume: 8
Issue: 3
Pages: 379-405
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Publication
29693305 | J:266196
First Author: Albertini G
Year: 2018
Journal: Glia
Title: Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice.
Volume: 66
Issue: 9
Pages: 1845-1861
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Publication
19695216 | J:154328
First Author: Shibasaki T
Year: 2009
Journal: Arch Biochem Biophys
Title: Aggravation of ischemia-reperfusion-triggered acute renal failure in xCT-deficient mice.
Volume: 490
Issue: 1
Pages: 63-9
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Publication
23085521 | J:193772
First Author: Kobayashi S
Year: 2012
Journal: Free Radic Biol Med
Title: Enhanced expression of cystine/glutamate transporter in the lung caused by the oxidative-stress-inducing agent paraquat.
Volume: 53
Issue: 12
Pages: 2197-203
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Publication
31101857 | J:281997
First Author: Kitagawa Y
Year: 2019
Journal: Sci Rep
Title: System xc- in microglia is a novel therapeutic target for post-septic neurological and psychiatric illness.
Volume: 9
Issue: 1
Pages: 7562
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Publication
11592818 | J:101645
First Author: Huizing M
Year: 2001
Journal: Mol Genet Metab
Title: Characterization of the murine gene corresponding to human Hermansky-Pudlak syndrome type 3: exclusion of the Subtle gray (sut) locus.
Volume: 74
Issue: 1-2
Pages: 217-25
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Publication
8699821 | J:31616
First Author: Swank RT
Year: 1996
Journal: Lab Anim Sci
Title: Inherited prolonged bleeding time and platelet storage pool deficiency in the subtle gray (sut) mouse.
Volume: 46
Issue: 1
Pages: 56-60
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37650924 | J:339862
     
First Author: de Baat A
Year: 2023
Journal: Diabetologia
Title: Cystine/glutamate antiporter System x(c)(-) deficiency impairs insulin secretion in mice.
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Publication
25384799 | J:346361
First Author: Mesci P
Year: 2015
Journal: Brain
Title: System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.
Volume: 138
Issue: Pt 1
Pages: 53-68
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Publication
31396687 | J:293326
First Author: Martis RM
Year: 2019
Journal: Histochem Cell Biol
Title: Mapping of the cystine-glutamate exchanger in the mouse eye: a role for xCT in controlling extracellular redox balance.
Volume: 152
Issue: 4
Pages: 293-310
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Publication
16399997 | J:108457
First Author: Burdo J
Year: 2006
Journal: J Histochem Cytochem
Title: Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum.
Volume: 54
Issue: 5
Pages: 549-57
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Publication
21397861 | J:169929
First Author: Ishimoto T
Year: 2011
Journal: Cancer Cell
Title: CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth.
Volume: 19
Issue: 3
Pages: 387-400
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Publication
26469940 | J:227125
First Author: Campbell A
Year: 2016
Journal: Glia
Title: Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia.
Volume: 64
Issue: 2
Pages: 227-39
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Publication
27801527 | J:241725
First Author: Hsieh CH
Year: 2017
Journal: J Pathol
Title: HIF-1α triggers long-lasting glutamate excitotoxicity via system xc- in cerebral ischaemia-reperfusion.
Volume: 241
Issue: 3
Pages: 337-349
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Publication
31000598 | J:275811
First Author: Lim JKM
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.
Volume: 116
Issue: 19
Pages: 9433-9442
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Publication
23848514 | J:316621
First Author: Wada T
Year: 2013
Journal: Cancer Sci
Title: Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia.
Volume: 104
Issue: 10
Pages: 1323-9
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Publication
31474565 | J:281556
First Author: Choi WM
Year: 2019
Journal: Cell Metab
Title: Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis.
Volume: 30
Issue: 5
Pages: 877-889.e7
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Publication
29167447 | J:257302
First Author: Yotsumoto S
Year: 2017
Journal: Sci Rep
Title: Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation.
Volume: 7
Issue: 1
Pages: 16026
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Publication
26601945 | J:230055
First Author: Shi J
Year: 2016
Journal: J Biol Chem
Title: Interleukin 1β Regulation of the System xc- Substrate-specific Subunit, xCT, in Primary Mouse Astrocytes Involves the RNA-binding Protein HuR.
Volume: 291
Issue: 4
Pages: 1643-51
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Publication
18621028 | J:139981
 
First Author: Takaki M
Year: 2008
Journal: Brain Res
Title: Molecular regulation of antioxidant ability in the hippocampus of EL mice.
Volume: 1228
Pages: 1-5
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Publication
15009730 | J:88797
First Author: Nguyen T
Year: 2004
Journal: J Invest Dermatol
Title: Characterization of melanosomes in murine Hermansky-Pudlak syndrome: mechanisms of hypopigmentation.
Volume: 122
Issue: 2
Pages: 452-60
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Publication
20463017 | J:288986
First Author: Mandal PK
Year: 2010
Journal: J Biol Chem
Title: System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency.
Volume: 285
Issue: 29
Pages: 22244-53
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Publication
32768484 | J:317468
 
First Author: Hu QX
Year: 2020
Journal: Neurochem Int
Title: Semi-quantitative distribution of excitatory amino acid (glutamate) transporters 1-3 (EAAT1-3) and the cystine-glutamate exchanger (xCT) in the adult murine spinal cord.
Volume: 140
Pages: 104811
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Publication
- | J:14274
 
First Author: Lane PW
Year: 1988
Journal: Mouse News Lett
Title: Subtle gray (sut); small with kinky tail (skt)
Volume: 80
Pages: 165
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Publication
33914705 | J:308502
 
First Author: Singhal R
Year: 2021
Journal: J Clin Invest
Title: HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
Volume: 131
Issue: 12
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Publication
32241947 | J:286610
First Author: Badgley MA
Year: 2020
Journal: Science
Title: Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Volume: 368
Issue: 6486
Pages: 85-89
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Publication
25429150 | J:218184
First Author: Williams LE
Year: 2014
Journal: J Neurosci
Title: Regulation of hippocampal synaptic strength by glial xCT.
Volume: 34
Issue: 48
Pages: 16093-102
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Publication
35941365 | J:329236
First Author: Nguyen KT
Year: 2022
Journal: Nat Cell Biol
Title: The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis.
Volume: 24
Issue: 8
Pages: 1239-1251
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Publication
28985506 | J:251938
First Author: Chen D
Year: 2017
Journal: Mol Cell
Title: NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression.
Volume: 68
Issue: 1
Pages: 224-232.e4
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Publication
29024663 | J:256101
First Author: Nasca C
Year: 2017
Journal: Neuron
Title: Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress.
Volume: 96
Issue: 2
Pages: 402-413.e5
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9585243 | J:88018
First Author: Swank RT
Year: 1998
Journal: Pigment Cell Res
Title: Mouse models of Hermansky Pudlak syndrome: a review.
Volume: 11
Issue: 2
Pages: 60-80
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29350434 | J:258726
First Author: Ottestad-Hansen S
Year: 2018
Journal: Glia
Title: The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain.
Volume: 66
Issue: 5
Pages: 951-970
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Publication
35147267 | J:326352
First Author: Yamaguchi H
Year: 2022
Journal: Dev Dyn
Title: Disruption of Trip11 in cranial neural crest cells is associated with increased ER and Golgi stress contributing to skull defects in mice.
Volume: 251
Issue: 7
Pages: 1209-1222
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32374849 | J:301391
First Author: Yu Y
Year: 2020
Journal: Blood
Title: Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis.
Volume: 136
Issue: 6
Pages: 726-739
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9714600 | J:48443
First Author: Odorizzi G
Year: 1998
Journal: Trends Cell Biol
Title: The AP-3 complex: a coat of many colours.
Volume: 8
Issue: 7
Pages: 282-8
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33665549 | J:306925
First Author: Menendez-Montes I
Year: 2021
Journal: iScience
Title: Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice.
Volume: 24
Issue: 2
Pages: 102124
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
19521566 | J:177549
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
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27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
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First Author: Mouse Genome Informatics
Year: 2010
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First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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First Author: Sharbeen G
Year: 2021
Journal: Cancer Res
Title: Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition.
Volume: 81
Issue: 13
Pages: 3461-3479
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First Author: Ananth S
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate.
Volume: 54
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Pages: 1592-602
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36478739 | J:331878
 
First Author: Zhang J
Year: 2022
Journal: Front Cell Dev Biol
Title: The RNA-binding protein RBM24 regulates lipid metabolism and SLC7A11 mRNA stability to modulate ferroptosis and inflammatory response.
Volume: 10
Pages: 1008576
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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