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Search results 1801 to 1900 out of 1950 for Pdgfrb

0.032s
Type Details Score
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 11, Shinichi Aizawa
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Keskin D
Year: 2015
Journal: Cell Rep
Title: Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2.
Volume: 10
Issue: 7
Pages: 1066-81
Publication  
First Author: Gao Z
Year: 2021
Journal: Biomolecules
Title: Partial Ablation of Non-Myogenic Progenitor Cells as a Therapeutic Approach to Duchenne Muscular Dystrophy.
Volume: 11
Issue: 10
Allele
Name: platelet derived growth factor receptor, beta polypeptide; targeted mutation 6, Philippe Soriano
Allele Type: Targeted
Attribute String: Inserted expressed sequence, No functional change
Allele
Name: transgene insertion JN169, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 35, Volkhard Lindner
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 9.1, Shinichi Aizawa
Allele Type: Targeted
Attribute String: Reporter
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 10.1, Shinichi Aizawa
Allele Type: Targeted
Attribute String: Reporter
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 11.1, Shinichi Aizawa
Allele Type: Targeted
Attribute String: Reporter
Allele
Name: platelet derived growth factor receptor, beta polypeptide; targeted mutation 1.2, Lorin E Olson
Allele Type: Targeted
Attribute String: Null/knockout, Recombinase
Allele
Name: platelet derived growth factor receptor, beta polypeptide; targeted mutation 1.1, Lorin E Olson
Allele Type: Targeted
Attribute String: Conditional ready, No functional change, Recombinase
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: C57BL/6NCrlj * CBA/JNCrlj
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: C57BL/6NCrlj * CBA/JNCrlj
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: C57BL/6NCrlj * CBA/JNCrlj
Zygosity: hm
Has Mutant Allele: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Publication
First Author: Orlich MM
Year: 2022
Journal: Circ Res
Title: Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow.
Volume: 131
Issue: 4
Pages: 308-327
Publication
First Author: Jiang Z
Year: 2021
Journal: Cell Rep
Title: PDGFRb+ mesenchymal cells, but not NG2+ mural cells, contribute to cardiac fat.
Volume: 34
Issue: 5
Pages: 108697
Allele
Name: platelet derived growth factor receptor, beta polypeptide; targeted mutation 5, Philippe Soriano
Allele Type: Targeted
Attribute String: Inserted expressed sequence, No functional change
Publication  
First Author: Choe YG
Year: 2022
Journal: Front Cell Neurosci
Title: Pericyte Loss Leads to Capillary Stalling Through Increased Leukocyte-Endothelial Cell Interaction in the Brain.
Volume: 16
Pages: 848764
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Li Z
Year: 2021
Journal: Nat Commun
Title: Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen.
Volume: 12
Issue: 1
Pages: 6386
Publication
First Author: Dobie R
Year: 2019
Journal: Cell Rep
Title: Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Volume: 29
Issue: 7
Pages: 1832-1847.e8
Allele
Name: transgene insertion 58, Rana Gupta
Allele Type: Transgenic
Attribute String: Transactivator
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Joffin N
Year: 2021
Journal: Cell Stem Cell
Title: Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue.
Volume: 28
Issue: 4
Pages: 702-717.e8
Allele
Name: transgene insertion 6096, Ralf H Adams
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Allele
Name: transgene insertion, Berislav V Zlokovic
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Genotype
Symbol: Pdgfrb/Pdgfrb
Background: either: 129S4/SvJaeSor-Pdgfra or (involves: 129S4/SvJaeSor * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Pdgfrb-EGFP)JN169Gsat/?
Background: involves: FVB/NTac
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pdgfrb-EGFP)JN169Gsat/?
Background: involves: C57BL/6 * FVB/NTac
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Lakhe-Reddy S
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Mesangial cell αvβ8-integrin regulates glomerular capillary integrity and repair.
Volume: 306
Issue: 12
Pages: F1400-9
Publication
First Author: Seynhaeve ALB
Year: 2018
Journal: Sci Rep
Title: Spatiotemporal endothelial cell - pericyte association in tumors as shown by high resolution 4D intravital imaging.
Volume: 8
Issue: 1
Pages: 9596
Publication    
First Author: Kirkwood PM
Year: 2022
Journal: Elife
Title: Single-cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation.
Volume: 11
Publication
First Author: Henderson NC
Year: 2013
Journal: Nat Med
Title: Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.
Volume: 19
Issue: 12
Pages: 1617-24
Strain
Attribute String: transgenic, mutant strain, congenic
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Gabriel Victora
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence
Publication
First Author: Keller A
Year: 2013
Journal: Nat Genet
Title: Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice.
Volume: 45
Issue: 9
Pages: 1077-82
Publication
First Author: Stobart JL
Year: 2023
Journal: J Cereb Blood Flow Metab
Title: Altered hemodynamics and vascular reactivity in a mouse model with severe pericyte deficiency.
Volume: 43
Issue: 5
Pages: 763-777
Publication
First Author: Wang S
Year: 2017
Journal: PLoS One
Title: Bim expression in endothelial cells and pericytes is essential for regression of the fetal ocular vasculature.
Volume: 12
Issue: 5
Pages: e0178198
Publication
First Author: Raymant M
Year: 2024
Journal: Nat Commun
Title: Macrophage-fibroblast JAK/STAT dependent crosstalk promotes liver metastatic outgrowth in pancreatic cancer.
Volume: 15
Issue: 1
Pages: 3593
Publication
First Author: Cooke VG
Year: 2012
Journal: Cancer Cell
Title: Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway.
Volume: 21
Issue: 1
Pages: 66-81
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Genotype
Symbol: Pdgfrb/Pdgfrb
Background: either: (involves: 129S4/SvJaeSor * 129S7/SvEvBrd) or (involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6)
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tert/Tert Tg(Pdgfrb-cre)35Vli/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Günter A
Year: 2023
Journal: Int J Mol Sci
Title: Mural Serum Response Factor (SRF) Deficiency Provides Insights into Retinal Vascular Functionality and Development.
Volume: 24
Issue: 16
Publication
First Author: Shan B
Year: 2021
Journal: Genes Dev
Title: Cold-responsive adipocyte progenitors couple adrenergic signaling to immune cell activation to promote beige adipocyte accrual.
Volume: 35
Issue: 19-20
Pages: 1333-1338
Publication
First Author: Zaitoun IS
Year: 2019
Journal: Sci Rep
Title: Bcl-2 Expression in Pericytes and Astrocytes Impacts Vascular Development and Homeostasis.
Volume: 9
Issue: 1
Pages: 9700
Publication
First Author: Chen X
Year: 2023
Journal: Skin Res Technol
Title: Autophagy gene Atg7 regulates the development of radiation-induced skin injury and fibrosis of skin.
Volume: 29
Issue: 6
Pages: e13337
Publication  
First Author: Daquinag AC
Year: 2020
Journal: Cells
Title: Glycosaminoglycan Modification of Decorin Depends on MMP14 Activity and Regulates Collagen Assembly.
Volume: 9
Issue: 12
Publication  
First Author: He L
Year: 2016
Journal: Sci Rep
Title: Analysis of the brain mural cell transcriptome.
Volume: 6
Pages: 35108
Publication
First Author: Bjørnholm KD
Year: 2023
Journal: Cell Rep Methods
Title: A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature.
Volume: 3
Issue: 3
Pages: 100431
Publication
First Author: Xue F
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Coordinated signaling of activating transcription factor 6α and inositol-requiring enzyme 1α regulates hepatic stellate cell-mediated fibrogenesis in mice.
Volume: 320
Issue: 5
Pages: G864-G879
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Genotype
Symbol: Pdgfrb/Pdgfrb
Background: either: (involves: 129S4/SvJaeSor * 129S7/SvEvBrd) or (involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6)
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Abcc6/Abcc6 Tg(Pdgfrb-cre)35Vli/?
Background: B6.Cg-Abcc6 Tg(Pdgfrb-cre)35Vli
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Baguma-Nibasheka M
Year: 2021
Journal: Cells
Title: Regulation of Transplanted Cell Homing by FGF1 and PDGFB after Doxorubicin Myocardial Injury.
Volume: 10
Issue: 11
Publication
First Author: Liu Y
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway.
Volume: 1865
Issue: 10
Pages: 2685-2693
Publication
First Author: Triplett TA
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.
Volume: 113
Issue: 8
Pages: E1016-25
Publication
First Author: Nakatsuka T
Year: 2017
Journal: Oncogene
Title: Impact of histone demethylase KDM3A-dependent AP-1 transactivity on hepatotumorigenesis induced by PI3K activation.
Volume: 36
Issue: 45
Pages: 6262-6271
Publication  
First Author: Li L
Year: 2022
Journal: J Clin Invest
Title: Lymph node fibroblastic reticular cells preserve a tolerogenic niche in allograft transplantation through laminin α4.
Volume: 132
Issue: 13
Publication
First Author: Nakatsuka A
Year: 2013
Journal: Circ Res
Title: Visceral adipose tissue-derived serine proteinase inhibitor inhibits apoptosis of endothelial cells as a ligand for the cell-surface GRP78/voltage-dependent anion channel complex.
Volume: 112
Issue: 5
Pages: 771-80
Publication  
First Author: Sorenson CM
Year: 2021
Journal: Front Cell Dev Biol
Title: Targeted Thrombospondin-1 Expression in Ocular Vascular Development and Neovascularization.
Volume: 9
Pages: 671989
Publication  
First Author: Goodwin AT
Year: 2023
Journal: Development
Title: Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation.
Volume: 150
Issue: 9
Publication  
First Author: Martin K
Year: 2016
Journal: Nat Commun
Title: PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis.
Volume: 7
Pages: 12502
Publication
First Author: Shao M
Year: 2021
Journal: Cell Stem Cell
Title: Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity.
Volume: 28
Issue: 4
Pages: 685-701.e7
Publication
First Author: Muhl L
Year: 2022
Journal: Dev Cell
Title: A single-cell transcriptomic inventory of murine smooth muscle cells.
Volume: 57
Issue: 20
Pages: 2426-2443.e6
Publication
First Author: Muhl L
Year: 2020
Journal: Nat Commun
Title: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination.
Volume: 11
Issue: 1
Pages: 3953
Publication    
First Author: Hepler C
Year: 2018
Journal: Elife
Title: Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice.
Volume: 7
Publication
First Author: Shan B
Year: 2022
Journal: Cell Metab
Title: Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity.
Volume: 34
Issue: 5
Pages: 783-799.e7
Publication
First Author: Shan B
Year: 2020
Journal: Nat Metab
Title: Perivascular mesenchymal cells control adipose-tissue macrophage accrual in obesity.
Volume: 2
Issue: 11
Pages: 1332-1349
Publication  
First Author: Gautam J
Year: 2016
Journal: Sci Rep
Title: The role of pericytic laminin in blood brain barrier integrity maintenance.
Volume: 6
Pages: 36450
Publication
First Author: Sakuma H
Year: 2024
Journal: Sci Rep
Title: Inducible deletion of microRNA activity in kidney mesenchymal cells exacerbates renal fibrosis.
Volume: 14
Issue: 1
Pages: 10963
Publication
First Author: Zhang C
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature.
Volume: 38
Issue: 11
Pages: 2691-2705
Publication
First Author: Cornuault L
Year: 2023
Journal: J Am Heart Assoc
Title: Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction.
Volume: 12
Issue: 13
Pages: e029279
Publication
First Author: Dar A
Year: 2024
Journal: Sci Rep
Title: Lineage tracing reveals a novel PDGFRβ(+) satellite cell subset that contributes to myo-regeneration of chronically injured rotator cuff muscle.
Volume: 14
Issue: 1
Pages: 9668
Publication  
First Author: Zhang Y
Year: 2018
Journal: Development
Title: Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels.
Volume: 145
Issue: 3
Publication    
First Author: O'Herron PJ
Year: 2022
Journal: Elife
Title: 3D optogenetic control of arteriole diameter in vivo.
Volume: 11
Publication
First Author: Kuppe C
Year: 2021
Journal: Nature
Title: Decoding myofibroblast origins in human kidney fibrosis.
Volume: 589
Issue: 7841
Pages: 281-286
Publication
First Author: Bailey J
Year: 2022
Journal: Diabetologia
Title: GLP-1 receptor nitration contributes to loss of brain pericyte function in a mouse model of diabetes.
Volume: 65
Issue: 9
Pages: 1541-1554
Publication
First Author: Hong SP
Year: 2020
Journal: Nat Commun
Title: Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi.
Volume: 11
Issue: 1
Pages: 4102
Publication  
First Author: Nelson AR
Year: 2020
Journal: Front Aging Neurosci
Title: Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo.
Volume: 12
Pages: 108
Publication
First Author: Munting LP
Year: 2023
Journal: J Cereb Blood Flow Metab
Title: Spontaneous vasomotion propagates along pial arterioles in the awake mouse brain like stimulus-evoked vascular reactivity.
Volume: 43
Issue: 10
Pages: 1752-1763
Publication    
First Author: Glück C
Year: 2021
Journal: Elife
Title: Distinct signatures of calcium activity in brain mural cells.
Volume: 10
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdgfrb-FLP1,Cspg4-cre/ERT2)#Bvz/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pdgfrb/Pdgfrb<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdgfrb-cre/ERT2)6096Rha/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Takahashi M
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Identification of gene expression profile of neural crest-derived cells isolated from submandibular glands of adult mice.
Volume: 446
Issue: 2
Pages: 481-6
Publication  
First Author: Wang Y
Year: 2023
Journal: Metabolism
Title: Hepatocyte Ninjurin2 promotes hepatic stellate cell activation and liver fibrosis through the IGF1R/EGR1/PDGF-BB signaling pathway.
Volume: 140
Pages: 155380
Publication
First Author: Å piranec K
Year: 2018
Journal: Circulation
Title: Endothelial C-Type Natriuretic Peptide Acts on Pericytes to Regulate Microcirculatory Flow and Blood Pressure.
Volume: 138
Issue: 5
Pages: 494-508
Publication
First Author: Å piranec Spes K
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Natriuretic Peptides Attenuate Retinal Pathological Neovascularization Via Cyclic Guanosine Monophosphate Signaling in Pericytes and Astrocytes.
Volume: 40
Issue: 1
Pages: 159-174
Publication      
First Author: He L
Year: 2020
Journal: bioRxiv
Title: Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2-implications for microvascular inflammation and hypercoagulopathy in COVID-19.
Publication    
First Author: Hepler C
Year: 2017
Journal: Elife
Title: Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice.
Volume: 6
Publication
First Author: Trinh VQ
Year: 2023
Journal: Sci Signal
Title: Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation.
Volume: 16
Issue: 787
Pages: eadf6696