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Search results 101 to 153 out of 153 for Elovl1

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Type Details Score
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Allele
Gt(ROSA)26Sor<tm2.1(CAG-ELOVL1)Geno> | MGI:6194785
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Genoway
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Publication
27124591 | J:257393
First Author: van de Beek MC
Year: 2016
Journal: PLoS One
Title: C26:0-Carnitine Is a New Biomarker for X-Linked Adrenoleukodystrophy in Mice and Man.
Volume: 11
Issue: 4
Pages: e0154597
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Genotype
Genotype
Symbol: Abcd1/? Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Cnp/Cnp<+>
Background: involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Abcd1/? Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(CMV-cre)1Cgn/?
Background: involves: 129 * BALB/cJ * C57BL/6J * Swiss
Zygosity: cn
Has Mutant Allele: true
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Protein
V9GXI2
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
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Protein
Q9WU14
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Protein
Q4V9V3
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: false
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Publication
9211877 | -
First Author: Oh CS
Year: 1997
Journal: J Biol Chem
Title: ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation.
Volume: 272
Issue: 28
Pages: 17376-84
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Protein Domain
IPR030457 | ELO_CS
Type: Conserved_site
Description: This entry represents a conserved site found in the ELO (Elongation of fatty acids protein) family members, such as:Mammalian proteins ELOVL1 (Elongation of very long chain fatty acids protein 1) to ELOVL4 []. These proteins all seem to beinvolved in the synthesis of very long chain fatty acids.Yeast ELO1, ELO2 and ELO3 []. They seem to be components of membrane-boundfatty acid elongation systems.Caenorhabditis elegans hypothetical protein C40H1.4.Caenorhabditis elegans hypothetical protein D2024.3.The proteins have from 271 to 435 amino acid residues. Structurally, they seemto be formed of three sections: a N-terminal region with two transmembranedomains, a central hydrophilic loop and a C-terminal region that contains fromone to three transmembrane domains. This entry represents aconserved region that contains three histidines. This region is located in thehydrophilic loop.
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Protein
A0A0G2JFD6
Organism: Mus musculus/domesticus
Length: 74  
Fragment?: false
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Publication
7768822 | -
First Author: el-Sherbeini M
Year: 1995
Journal: J Bacteriol
Title: Cloning and characterization of GNS1: a Saccharomyces cerevisiae gene involved in synthesis of 1,3-beta-glucan in vitro.
Volume: 177
Issue: 11
Pages: 3227-34
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Publication
8027068 | -
First Author: García-Arranz M
Year: 1994
Journal: J Biol Chem
Title: Transcriptional control of yeast plasma membrane H(+)-ATPase by glucose. Cloning and characterization of a new gene involved in this regulation.
Volume: 269
Issue: 27
Pages: 18076-82
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Publication
29458843 | -
 
First Author: Wang Q
Year: 2018
Journal: Microbiol Res
Title: A critical role for very long-chain fatty acid elongases in oleic acid-mediated Saccharomyces cerevisiae cytotoxicity.
Volume: 207
Pages: 1-7
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Publication
21959040 | -
First Author: Naganuma T
Year: 2011
Journal: FEBS Lett
Title: Biochemical characterization of the very long-chain fatty acid elongase ELOVL7.
Volume: 585
Issue: 20
Pages: 3337-41
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Publication
30487246 | -
First Author: Mueller N
Year: 2019
Journal: J Med Genet
Title: De novo mutation in ELOVL1 causes ichthyosis, acanthosis nigricans, hypomyelination, spastic paraplegia, high frequency deafness and optic atrophy.
Volume: 56
Issue: 3
Pages: 164-175
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Protein Domain
IPR002076 | ELO_fam
Type: Family
Description: The ELO family consist of eukaryotic integral membrane proteins involved in fatty acid elongation. This family consist of:Mammalian proteins ELOVL1 to ELOVL7 [, ]. These proteins catalyse the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle, each of them has a specific substrate specificity and physiological functions.Yeast ELO1, ELO2 and ELO3 [, ]. They are components of a microsomal membrane-bound long-chain fatty acid elongation system.Caenorhabditis elegans hypothetical protein C40H1.4.Caenorhabditis elegans hypothetical protein D2024.3.This group of eukaryotic integral membrane proteinsare evolutionary related and have from 290 to 435 amino acid residues. Structurally, they seem to be formed of three sections: a N-terminal region with two transmembrane domains, a central hydrophilic loop and a C-terminal region that contains from one to three transmembrane domains. Members of this family are involved in long chain fatty acid elongation systems that produce the 26-carbon precursors for ceramide and sphingolipid synthesis []. Yeast ELO3 () affects plasma membrane H+-ATPase activity, and may act on a glucose-signalling pathway that controls the expression of several genes that are transcriptionally regulated by glucose such as PMA1 []. It plays an important role in lipotoxic cell death induced by oleic acid through maintaining a balanced fatty acid composition in the plasma membrane []. Mammalian ELOVLs are also associated with known pathologies. ELOVL1 catalyses elongation of saturated and monounsaturated C22-C26-VLCFAs, and dominant mutations cause ichthyosis, hypomyelination of the central white matter that leads to spastic paraplegia and central nystagmus and optic atrophy [], dominant ELOVL4 mutations cause a juvenile macular dystrophy (Stargardt disease-3) and Elovl4 knockout mice die soon after birth due to a deficiency in skin barrier formation. Studies in Elovl6-null mice have revealed that ELOVL6 is involved in an obesity-induced insulin resistance and ELOVL7 is involved in prostate cancer growth [].
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Publication
31974308 | J:287986
First Author: Yamamoto H
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Skin permeability barrier formation by the ichthyosis-causative gene FATP4 through formation of the barrier lipid ω-O-acylceramide.
Volume: 117
Issue: 6
Pages: 2914-2922
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Protein
Q9D2Y9
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
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Protein
Q9JLJ4
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
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Protein
Q920L5
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: false
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Protein
Q9EQC4
Organism: Mus musculus/domesticus
Length: 312  
Fragment?: false
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Protein
O35949
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: false
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Protein
X2EXH0
Organism: Mus musculus/domesticus
Length: 273  
Fragment?: true
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Protein
A0A498WFQ4
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
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Protein
A0A0R4J1P7
Organism: Mus musculus/domesticus
Length: 275  
Fragment?: false
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Protein
A0A0G2JFE8
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: true
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Protein
Q543J1
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
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Protein
Q8BHI7
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: false
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Protein
A0A0G2JGX5
Organism: Mus musculus/domesticus
Length: 36  
Fragment?: true
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Protein
Q3TS46
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
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Protein
A0A286YCI1
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: false
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Protein
D3Z0Z6
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: true
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Protein
X2EXE4
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: true
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Protein
D3Z136
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Publication
25255441 | J:220625
First Author: Muneer Z
Year: 2014
Journal: PLoS One
Title: Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice.
Volume: 9
Issue: 9
Pages: e108655
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Publication
21738729 | J:174425
First Author: Fernandez C
Year: 2011
Journal: PLoS One
Title: Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice.
Volume: 6
Issue: 6
Pages: e21603
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