Type |
Details |
Score |
Protein Domain |
Type: |
Family |
Description: |
Cdc42 is an essential GTPase that belongs to the Rho family of Ras-like GTPases. These proteins act as molecular switches by responding to exogenous and/or endogenous signals and relaying those signals to activate downstream components of a biological pathway. Cdc42 transduces signals to the actin cytoskeleton to initiate and maintain polarized growth and to mitogen-activated protein morphogenesis. In Saccharomyces cerevisiae, Cdc42 plays an important role in multiple actin-dependent morphogenetic events such as bud emergence, mating-projection formation, and pseudohyphal growth []. In mammalian cells, Cdc42 regulates a variety of actin-dependent events and induces the JNK/SAPK protein kinase cascade, which leads to the activation of transcription factors within the nucleus []. Cdc42 mediates these processes through interactions with a myriad of downstream effectors, whose number and regulation we are just starting to understand. In addition, Cdc42 has been implicated in a number of human diseases through interactions with its regulators and downstream effectors []. |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Tetley GJN |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK. |
Volume: |
292 |
Issue: |
27 |
Pages: |
11361-11373 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johnson DI |
Year: |
1999 |
Journal: |
Microbiol Mol Biol Rev |
Title: |
Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity. |
Volume: |
63 |
Issue: |
1 |
Pages: |
54-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bi E |
Year: |
2000 |
Journal: |
Mol Biol Cell |
Title: |
Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast. |
Volume: |
11 |
Issue: |
2 |
Pages: |
773-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirsch DS |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes. |
Volume: |
276 |
Issue: |
2 |
Pages: |
875-83 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6379644 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2019-12-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3799115 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:6379665 |
Age: |
embryonic day 9.5 |
Image: |
11 Cdc42 Ednra-/- |
Note: |
Expression fails to localize at leading edges of migrating cardiac neural crest cells (CNCC). |
Specimen Label: |
11 Cdc42 Ednra-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6379644 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2019-12-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3799115 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:6379665 |
Age: |
embryonic day 9.5 |
Image: |
11 Cdc42 WT |
Note: |
Expression localized mainly at anterior migratory front of cardiac neural crest cells (CNCC). Expression accumulates at edge of cells in stream of CNCC migrating along outflow tract, but not in CNCC within pharyngeal arches. |
Specimen Label: |
11 Cdc42 WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Joberty G |
Year: |
1999 |
Journal: |
Mol Cell Biol |
Title: |
The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins. |
Volume: |
19 |
Issue: |
10 |
Pages: |
6585-97 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
191
|
Fragment?: |
false |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Reddy-Alla S |
Year: |
2010 |
Journal: |
Eur J Neurosci |
Title: |
PH-domain-driven targeting of collybistin but not Cdc42 activation is required for synaptic gephyrin clustering. |
Volume: |
31 |
Issue: |
7 |
Pages: |
1173-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schnack C |
Year: |
2008 |
Journal: |
Neuroscience |
Title: |
Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with Cdc42 effector proteins. |
Volume: |
154 |
Issue: |
4 |
Pages: |
1450-7 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee K |
Year: |
2013 |
Journal: |
Infect Immun |
Title: |
Cdc42 promotes host defenses against fatal infection. |
Volume: |
81 |
Issue: |
8 |
Pages: |
2714-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Allen WE |
Year: |
1998 |
Journal: |
J Cell Biol |
Title: |
A role for Cdc42 in macrophage chemotaxis. |
Volume: |
141 |
Issue: |
5 |
Pages: |
1147-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nalbant P |
Year: |
2004 |
Journal: |
Science |
Title: |
Activation of endogenous Cdc42 visualized in living cells. |
Volume: |
305 |
Issue: |
5690 |
Pages: |
1615-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aizawa R |
Year: |
2019 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Cdc42 regulates cranial suture morphogenesis and ossification. |
Volume: |
512 |
Issue: |
2 |
Pages: |
145-149 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang L |
Year: |
2007 |
Journal: |
Blood |
Title: |
Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis. |
Volume: |
110 |
Issue: |
12 |
Pages: |
3853-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki W |
Year: |
2015 |
Journal: |
Endocrinology |
Title: |
Cdc42 is critical for cartilage development during endochondral ossification. |
Volume: |
156 |
Issue: |
1 |
Pages: |
314-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen L |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. |
Volume: |
103 |
Issue: |
44 |
Pages: |
16520-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakamori R |
Year: |
2014 |
Journal: |
Cancer Res |
Title: |
CDC42 inhibition suppresses progression of incipient intestinal tumors. |
Volume: |
74 |
Issue: |
19 |
Pages: |
5480-92 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6189932 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Cdc42 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6189932 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Cdc42 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6189932 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Cdc42 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6189932 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Cdc42 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189932 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Cdc42 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189932 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Cdc42 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189932 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Cdc42 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mohammadi S |
Year: |
2013 |
Journal: |
J Cell Biol |
Title: |
Cdc42 interacts with the exocyst complex to promote phagocytosis. |
Volume: |
200 |
Issue: |
1 |
Pages: |
81-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han JS |
Year: |
2000 |
Journal: |
Exp Mol Med |
Title: |
Molecular cloning and sequencing of rat Cdc42 GTPase cDNA. |
Volume: |
32 |
Issue: |
3 |
Pages: |
115-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luckashenak N |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo. |
Volume: |
190 |
Issue: |
1 |
Pages: |
27-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshida Y |
Year: |
2021 |
Journal: |
Dev Biol |
Title: |
Cdc42 has important roles in postnatal angiogenesis and vasculature formation. |
Volume: |
477 |
|
Pages: |
64-69 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagahama R |
Year: |
2016 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Rho GTPase protein Cdc42 is critical for postnatal cartilage development. |
Volume: |
470 |
Issue: |
4 |
Pages: |
813-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi SY |
Year: |
2013 |
Journal: |
J Am Soc Nephrol |
Title: |
Cdc42 deficiency causes ciliary abnormalities and cystic kidneys. |
Volume: |
24 |
Issue: |
9 |
Pages: |
1435-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mori Y |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
Cdc42 is required for male germline niche development in mice. |
Volume: |
36 |
Issue: |
7 |
Pages: |
109550 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gong TW |
Year: |
1997 |
Journal: |
Biochim Biophys Acta |
Title: |
Complete cDNAs for CDC42 from chicken cochlea and mouse liver. |
Volume: |
1352 |
Issue: |
3 |
Pages: |
282-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo F |
Year: |
2009 |
Journal: |
Blood |
Title: |
Rho GTPase Cdc42 is essential for B-lymphocyte development and activation. |
Volume: |
114 |
Issue: |
14 |
Pages: |
2909-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ito TK |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis. |
Volume: |
9 |
Issue: |
7 |
Pages: |
e102186 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roney KE |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. |
Volume: |
6 |
Issue: |
9 |
Pages: |
e24795 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maillet M |
Year: |
2009 |
Journal: |
J Clin Invest |
Title: |
Cdc42 is an antihypertrophic molecular switch in the mouse heart. |
Volume: |
119 |
Issue: |
10 |
Pages: |
3079-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garvalov BK |
Year: |
2007 |
Journal: |
J Neurosci |
Title: |
Cdc42 regulates cofilin during the establishment of neuronal polarity. |
Volume: |
27 |
Issue: |
48 |
Pages: |
13117-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heynen SR |
Year: |
2011 |
Journal: |
Mol Vis |
Title: |
Retinal degeneration modulates intracellular localization of CDC42 in photoreceptors. |
Volume: |
17 |
|
Pages: |
2934-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang JB |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L. |
Volume: |
280 |
Issue: |
24 |
Pages: |
22883-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu X |
Year: |
2006 |
Journal: |
Genes Dev |
Title: |
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin. |
Volume: |
20 |
Issue: |
5 |
Pages: |
571-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng J |
Year: |
2018 |
Journal: |
J Dent Res |
Title: |
Epithelial Cdc42 Deletion Induced Enamel Organ Defects and Cystogenesis. |
Volume: |
97 |
Issue: |
12 |
Pages: |
1346-1354 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishikimi A |
Year: |
2005 |
Journal: |
FEBS Lett |
Title: |
Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes. |
Volume: |
579 |
Issue: |
5 |
Pages: |
1039-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Laviña B |
Year: |
2018 |
Journal: |
Development |
Title: |
Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations. |
Volume: |
145 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shitara A |
Year: |
2019 |
Journal: |
Mol Biol Cell |
Title: |
Cdc42 negatively regulates endocytosis during apical membrane maintenance in live animals. |
Volume: |
30 |
Issue: |
3 |
Pages: |
324-332 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tokizane K |
Year: |
2017 |
Journal: |
Glia |
Title: |
Phospholipid localization implies microglial morphology and function via Cdc42 in vitro. |
Volume: |
65 |
Issue: |
5 |
Pages: |
740-755 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen Y |
Year: |
2008 |
Journal: |
Dev Cell |
Title: |
Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells. |
Volume: |
14 |
Issue: |
3 |
Pages: |
342-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jin D |
Year: |
2015 |
Journal: |
Biochem J |
Title: |
Functional cross-talk between Cdc42 and two downstream targets, Par6B and PAK4. |
Volume: |
467 |
Issue: |
2 |
Pages: |
293-302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heinrich A |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
Cdc42 activity in Sertoli cells is essential for maintenance of spermatogenesis. |
Volume: |
37 |
Issue: |
4 |
Pages: |
109885 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oshima-Nakayama M |
Year: |
2016 |
Journal: |
Bone Rep |
Title: |
Cdc42 is crucial for facial and palatal formation during craniofacial development. |
Volume: |
5 |
|
Pages: |
1-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mizukawa B |
Year: |
2017 |
Journal: |
Blood |
Title: |
The cell polarity determinant CDC42 controls division symmetry to block leukemia cell differentiation. |
Volume: |
130 |
Issue: |
11 |
Pages: |
1336-1346 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wirth A |
Year: |
2013 |
Journal: |
Biochem J |
Title: |
Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties. |
Volume: |
456 |
Issue: |
3 |
Pages: |
311-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kholmanskikh SS |
Year: |
2006 |
Journal: |
Nat Neurosci |
Title: |
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility. |
Volume: |
9 |
Issue: |
1 |
Pages: |
50-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma Y |
Year: |
2021 |
Journal: |
Development |
Title: |
Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development. |
Volume: |
148 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bruurs LJ |
Year: |
2015 |
Journal: |
J Cell Biol |
Title: |
ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization. |
Volume: |
210 |
Issue: |
7 |
Pages: |
1055-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Szczur K |
Year: |
2009 |
Journal: |
Blood |
Title: |
The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signaling. |
Volume: |
114 |
Issue: |
20 |
Pages: |
4527-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar S |
Year: |
2012 |
Journal: |
Blood |
Title: |
Cdc42 regulates neutrophil migration via crosstalk between WASp, CD11b, and microtubules. |
Volume: |
120 |
Issue: |
17 |
Pages: |
3563-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakamoto I |
Year: |
2018 |
Journal: |
Exp Neurol |
Title: |
Roles of Cdc42 and Rac in Bergmann glia during cerebellar corticogenesis. |
Volume: |
302 |
|
Pages: |
57-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blattner SM |
Year: |
2013 |
Journal: |
Kidney Int |
Title: |
Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury. |
Volume: |
84 |
Issue: |
5 |
Pages: |
920-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fantin A |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells. |
Volume: |
11 |
Issue: |
10 |
Pages: |
1577-90 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
409
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
254
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
150
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
349
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
409
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wan H |
Year: |
2013 |
Journal: |
Dev Biol |
Title: |
CDC42 is required for structural patterning of the lung during development. |
Volume: |
374 |
Issue: |
1 |
Pages: |
46-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang L |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow. |
Volume: |
104 |
Issue: |
12 |
Pages: |
5091-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gamell C |
Year: |
2008 |
Journal: |
J Cell Sci |
Title: |
BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity. |
Volume: |
121 |
Issue: |
Pt 23 |
Pages: |
3960-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nalapareddy K |
Year: |
2021 |
Journal: |
iScience |
Title: |
Suppression of elevated Cdc42 activity promotes the regenerative potential of aged intestinal stem cells. |
Volume: |
24 |
Issue: |
4 |
Pages: |
102362 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cappello S |
Year: |
2006 |
Journal: |
Nat Neurosci |
Title: |
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. |
Volume: |
9 |
Issue: |
9 |
Pages: |
1099-107 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu X |
Year: |
2007 |
Journal: |
Dev Dyn |
Title: |
Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development. |
Volume: |
236 |
Issue: |
10 |
Pages: |
2767-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tskvitaria-Fuller I |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization. |
Volume: |
177 |
Issue: |
3 |
Pages: |
1708-20 |
|
•
•
•
•
•
|