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Search results 101 to 200 out of 209 for P2ry12

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Type Details Score
Publication
25100587 | J:215581
First Author: Eyo UB
Year: 2014
Journal: J Neurosci
Title: Neuronal hyperactivity recruits microglial processes via neuronal NMDA receptors and microglial P2Y12 receptors after status epilepticus.
Volume: 34
Issue: 32
Pages: 10528-40
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Publication
37167975 | J:350833
First Author: Cao K
Year: 2023
Journal: Curr Biol
Title: Microglia modulate general anesthesia through P2Y(12) receptor.
Volume: 33
Issue: 11
Pages: 2187-2200.e6
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Publication
23850619 | J:210778
First Author: Herfindal L
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets.
Volume: 437
Issue: 4
Pages: 603-8
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Publication
31434806 | J:295443
 
First Author: Hao Y
Year: 2019
Journal: JCI Insight
Title: Targetable purinergic receptors P2Y12 and A2b antagonistically regulate bladder function.
Volume: 4
Issue: 16
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Publication
24510394 | J:229344
First Author: West LE
Year: 2014
Journal: Cardiovasc Res
Title: Vessel wall, not platelet, P2Y12 potentiates early atherogenesis.
Volume: 102
Issue: 3
Pages: 429-35
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Publication
26988592 | J:246687
First Author: Boulaftali Y
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice.
Volume: 36
Issue: 5
Pages: 792-9
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Publication
28753204 | J:268897
First Author: Kamiyama M
Year: 2017
Journal: Cell Death Differ
Title: ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.
Volume: 24
Issue: 12
Pages: 2066-2076
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Publication
19822647 | J:154171
First Author: Paruchuri S
Year: 2009
Journal: J Exp Med
Title: Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor.
Volume: 206
Issue: 11
Pages: 2543-55
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Publication
25208846 | J:217904
First Author: Yu W
Year: 2014
Journal: FASEB J
Title: ADP-induced bladder contractility is mediated by P2Y12 receptor and temporally regulated by ectonucleotidases and adenosine signaling.
Volume: 28
Issue: 12
Pages: 5288-98
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Publication
37742194 | J:341989
First Author: Weilinger NL
Year: 2023
Journal: Cell Rep
Title: Pannexin-1 opening in neuronal edema causes cell death but also leads to protection via increased microglia contacts.
Volume: 42
Issue: 10
Pages: 113128
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Publication
35201268 | J:327482
 
First Author: Császár E
Year: 2022
Journal: J Exp Med
Title: Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions.
Volume: 219
Issue: 3
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Publication
19525944 | J:163956
First Author: Orr AG
Year: 2009
Journal: Nat Neurosci
Title: Adenosine A(2A) receptor mediates microglial process retraction.
Volume: 12
Issue: 7
Pages: 872-8
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Publication
20664064 | J:185405
First Author: Kronlage M
Year: 2010
Journal: Sci Signal
Title: Autocrine purinergic receptor signaling is essential for macrophage chemotaxis.
Volume: 3
Issue: 132
Pages: ra55
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Publication
34157360 | J:310641
     
First Author: Li C
Year: 2021
Journal: Neurosci Res
Title: A mouse model of microglia-specific ablation in the embryonic central nervous system.
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Publication
33188776 | J:299738
First Author: Liu Y
Year: 2020
Journal: Cell
Title: High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue.
Volume: 183
Issue: 6
Pages: 1665-1681.e18
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Publication
36055226 | J:328531
First Author: Ma C
Year: 2022
Journal: Cancer Cell
Title: Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD.
Volume: 40
Issue: 9
Pages: 986-998.e5
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Publication
35379828 | J:324292
First Author: Mills WA 3rd
Year: 2022
Journal: Nat Commun
Title: Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age.
Volume: 13
Issue: 1
Pages: 1794
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Publication
33176450 | J:318571
First Author: Xiang B
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Calcium Ion Chelation Preserves Platelet Function During Cold Storage.
Volume: 41
Issue: 1
Pages: 234-249
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Publication
31826978 | J:283554
 
First Author: Lee RH
Year: 2019
Journal: Sci Transl Med
Title: Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: Mechanisms and implications.
Volume: 11
Issue: 522
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Publication
24244016 | J:207114
First Author: Cummings HE
Year: 2013
Journal: J Immunol
Title: Cutting edge: Leukotriene C4 activates mouse platelets in plasma exclusively through the type 2 cysteinyl leukotriene receptor.
Volume: 191
Issue: 12
Pages: 5807-10
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Publication
31896673 | J:287984
First Author: Diaz-Aparicio I
Year: 2020
Journal: J Neurosci
Title: Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome.
Volume: 40
Issue: 7
Pages: 1453-1482
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Publication
27373153 | J:238587
First Author: Gu N
Year: 2016
Journal: Cell Rep
Title: Spinal Microgliosis Due to Resident Microglial Proliferation Is Required for Pain Hypersensitivity after Peripheral Nerve Injury.
Volume: 16
Issue: 3
Pages: 605-14
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Publication
29694903 | J:271131
First Author: Eyo UB
Year: 2018
Journal: Cell Rep
Title: P2Y12R-Dependent Translocation Mechanisms Gate the Changing Microglial Landscape.
Volume: 23
Issue: 4
Pages: 959-966
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Publication
33951432 | J:324649
First Author: Eyo UB
Year: 2021
Journal: Cell Rep
Title: Microglia provide structural resolution to injured dendrites after severe seizures.
Volume: 35
Issue: 5
Pages: 109080
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Publication
22075250 | J:195974
First Author: Stefanini L
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Rap1-Rac1 circuits potentiate platelet activation.
Volume: 32
Issue: 2
Pages: 434-41
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Publication
20971951 | J:168407
First Author: Stolla M
Year: 2011
Journal: Blood
Title: The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy.
Volume: 117
Issue: 3
Pages: 1005-13
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Publication
25972159 | J:224612
First Author: Chen S
Year: 2015
Journal: Blood
Title: MicroRNA-155-deficient dendritic cells cause less severe GVHD through reduced migration and defective inflammasome activation.
Volume: 126
Issue: 1
Pages: 103-12
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Publication
12835326 | J:85425
First Author: Schulz A
Year: 2003
Journal: J Biol Chem
Title: The structural evolution of a P2Y-like G-protein-coupled receptor.
Volume: 278
Issue: 37
Pages: 35531-41
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Publication
17673465 | J:125348
First Author: Schoenwaelder SM
Year: 2007
Journal: J Biol Chem
Title: Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets.
Volume: 282
Issue: 39
Pages: 28648-58
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Publication
31135881 | J:279267
First Author: Sasaki F
Year: 2019
Journal: Int Immunol
Title: The leukotriene receptors as therapeutic targets of inflammatory diseases.
Volume: 31
Issue: 9
Pages: 607-615
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Publication
17158345 | J:129299
First Author: Offermanns S
Year: 2006
Journal: Circ Res
Title: Activation of platelet function through G protein-coupled receptors.
Volume: 99
Issue: 12
Pages: 1293-304
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Publication
32999463 | J:297311
First Author: Badimon A
Year: 2020
Journal: Nature
Title: Negative feedback control of neuronal activity by microglia.
Volume: 586
Issue: 7829
Pages: 417-423
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Publication
31628458 | J:293626
First Author: Allon G
Year: 2019
Journal: Hum Mol Genet
Title: PRCD is concentrated at the base of photoreceptor outer segments and is involved in outer segment disc formation.
Volume: 28
Issue: 24
Pages: 4078-4088
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Publication
15914557 | J:118491
First Author: Tolhurst G
Year: 2005
Journal: Blood
Title: Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling.
Volume: 106
Issue: 5
Pages: 1644-51
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Publication
22814751 | J:201481
First Author: O'Brien KA
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β.
Volume: 32
Issue: 9
Pages: 2232-40
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Publication
36753421 | J:333946
First Author: Hattori Y
Year: 2023
Journal: Cell Rep
Title: CD206(+) macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia.
Volume: 42
Issue: 2
Pages: 112092
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Publication
29925524 | J:341082
First Author: Casari C
Year: 2018
Journal: Blood Adv
Title: Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets.
Volume: 2
Issue: 12
Pages: 1417-1428
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Publication
38131301 | J:344137
   
First Author: He Y
Year: 2023
Journal: Elife
Title: Microglia facilitate and stabilize the response to general anesthesia via modulating the neuronal network in a brain region-specific manner.
Volume: 12
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Publication
21413988 | J:186298
First Author: Chen D
Year: 2011
Journal: J Anat
Title: Expression of P2Y(6) receptors in the developing mouse skeletal muscle and after injury and repair.
Volume: 218
Issue: 6
Pages: 643-51
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Publication
35609421 | J:326255
 
First Author: Chen Y
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Microglial integrin, chemokine receptors, and inflammatory response vary with development.
Volume: 615
Pages: 94-101
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Publication
30033152 | J:269384
First Author: Cheadle L
Year: 2018
Journal: Neuron
Title: Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement.
Volume: 99
Issue: 3
Pages: 525-539.e10
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Publication
35567352 | J:326459
First Author: Scott EP
Year: 2022
Journal: Glia
Title: The zinc finger transcription factor Sall1 is required for the early developmental transition of microglia in mouse embryos.
Volume: 70
Issue: 9
Pages: 1720-1733
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Publication
39841599 | J:361494
First Author: Lehtonen H
Year: 2025
Journal: Cell Rep
Title: Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance.
Volume: 44
Issue: 2
Pages: 115227
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Publication
23479225 | J:194901
First Author: Través PG
Year: 2013
Journal: J Immunol
Title: Selective impairment of P2Y signaling by prostaglandin E2 in macrophages: implications for Ca2+-dependent responses.
Volume: 190
Issue: 8
Pages: 4226-35
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Publication
32242005 | J:287499
First Author: Hattori Y
Year: 2020
Journal: Nat Commun
Title: Transient microglial absence assists postmigratory cortical neurons in proper differentiation.
Volume: 11
Issue: 1
Pages: 1631
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Publication
27721240 | J:239619
First Author: Rué L
Year: 2016
Journal: J Clin Invest
Title: Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
Volume: 126
Issue: 11
Pages: 4319-4330
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Publication
26884166 | J:317789
First Author: Bennett ML
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: New tools for studying microglia in the mouse and human CNS.
Volume: 113
Issue: 12
Pages: E1738-46
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Publication
36130488 | J:329269
First Author: Cserép C
Year: 2022
Journal: Cell Rep
Title: Microglial control of neuronal development via somatic purinergic junctions.
Volume: 40
Issue: 12
Pages: 111369
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Publication
32259484 | J:292317
First Author: Utz SG
Year: 2020
Journal: Cell
Title: Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development.
Volume: 181
Issue: 3
Pages: 557-573.e18
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Publication
38750507 | J:354190
First Author: Morimoto K
Year: 2024
Journal: Inflamm Regen
Title: Maternal immunoglobulins are distributed in the offspring's brain to support the maintenance of cortical interneurons in the postnatal period.
Volume: 44
Issue: 1
Pages: 24
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Publication
34428430 | J:314108
First Author: Jecrois ES
Year: 2021
Journal: Dev Cell
Title: Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.
Volume: 56
Issue: 20
Pages: 2871-2885.e6
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Publication
35444273 | J:330324
First Author: Masuda T
Year: 2022
Journal: Nature
Title: Specification of CNS macrophage subsets occurs postnatally in defined niches.
Volume: 604
Issue: 7907
Pages: 740-748
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Publication
38101413 | J:344239
First Author: Wang Y
Year: 2024
Journal: Dev Cell
Title: BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development.
Volume: 59
Issue: 1
Pages: 108-124.e7
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Publication
33887203 | J:305421
First Author: Rosin JM
Year: 2021
Journal: Dev Cell
Title: A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors.
Volume: 56
Issue: 9
Pages: 1326-1345.e6
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Publication
23525041 | J:197621
First Author: Ueno M
Year: 2013
Journal: Nat Neurosci
Title: Layer V cortical neurons require microglial support for survival during postnatal development.
Volume: 16
Issue: 5
Pages: 543-51
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Publication
30635555 | J:270210
First Author: Loo L
Year: 2019
Journal: Nat Commun
Title: Single-cell transcriptomic analysis of mouse neocortical development.
Volume: 10
Issue: 1
Pages: 134
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Strain
MGI:5450890 | B6;129-P2ry12<tm1Dgen>/H
Attribute String: mutant stock, targeted mutation
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GXD Expression
GXD Expression
Probe: MGI:7488354
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7488358
Age: embryonic day 12.5
Image: 1A E12.5 CD206
Note: Expression in cells intermingled with P2ry12-expressing cells. Cells co-expressing P2ry12 frequently detected at E12.5 and E13.5.
Specimen Label: 1A E12.5 CD206
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7488354
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3819021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7488358
Age: embryonic day 13.5
Image: 1A E13.5 CD206
Note: Expression in cells intermingled with P2ry12-expressing cells. Cells co-expressing P2ry12 frequently detected at E12.5 and E13.5.
Specimen Label: 1A E13.5 CD206
Detected: true
Specimen Num: 2
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Allele
P2ry12<em1Smoc> | MGI:7291504
Name: purinergic receptor P2Y, G-protein coupled 12; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6475947 | C57BL/6JSmoc-P2ry12<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
P2ry12<em1(cre/ERT2)Peng> | MGI:7450934
Name: purinergic receptor P2Y, G-protein coupled 12; endonuclease-mediated mutation 1, Bo Peng
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase, Reporter
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Allele
P2ry12<tm1Cjf> | MGI:2445936
Name: purinergic receptor P2Y, G-protein coupled 12; targeted mutation 1, Carolyn J Foster
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
P2ry12<tm1Pcon> | MGI:2674084
Name: purinergic receptor P2Y, G-protein coupled 12; targeted mutation 1, Pamela B Conley
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: P2ry12/P2ry12<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: P2ry12/P2ry12
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: P2ry12/P2ry12
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0060692 | platelet-type bleeding disorder 8
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Allele
P2ry12<em1(icre/ERT2)Tda> | MGI:6379582
Name: purinergic receptor P2Y, G-protein coupled 12; endonuclease-mediated mutation 1, Thomas D Arnold
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Strain
MGI:6423089 | B6(129S6)-P2ry12<em1(icre/ERT2)Tda>/J
Attribute String: mutant strain, endonuclease-mediated mutation
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Publication
38990806 | J:351141
First Author: Bakina O
Year: 2024
Journal: PLoS One
Title: In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia.
Volume: 19
Issue: 7
Pages: e0302376
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Publication
39021809 | J:351626
First Author: Carrier M
Year: 2024
Journal: iScience
Title: Bone marrow-derived myeloid cells transiently colonize the brain during postnatal development and interact with glutamatergic synapses.
Volume: 27
Issue: 7
Pages: 110037
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