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Search results 2001 to 2100 out of 2663 for Cp

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Category: Publication
Type Details Score
Publication
First Author: Zanesi N
Year: 2006
Journal: Cancer Res
Title: Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
Volume: 66
Issue: 2
Pages: 915-20
Publication
First Author: Weston CJ
Year: 2015
Journal: J Clin Invest
Title: Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.
Volume: 125
Issue: 2
Pages: 501-20
Publication
First Author: Schlenner S
Year: 2019
Journal: Ann Rheum Dis
Title: NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology.
Volume: 78
Issue: 3
Pages: 342-349
Publication
First Author: Yin J
Year: 2018
Journal: Am J Hum Genet
Title: Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome.
Volume: 102
Issue: 2
Pages: 296-308
Publication
First Author: Han P
Year: 2014
Journal: Nature
Title: A long noncoding RNA protects the heart from pathological hypertrophy.
Volume: 514
Issue: 7520
Pages: 102-106
Publication  
First Author: Mani V
Year: 2019
Journal: Science
Title: Migratory DCs activate TGF-β to precondition naïve CD8+ T cells for tissue-resident memory fate.
Volume: 366
Issue: 6462
Publication
First Author: El Hamdaoui Y
Year: 2022
Journal: Mol Psychiatry
Title: Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs.
Volume: 27
Issue: 12
Pages: 5070-5085
Publication
First Author: Paudel B
Year: 2024
Journal: Nat Commun
Title: Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer's disease and aging.
Volume: 15
Issue: 1
Pages: 264
Publication
First Author: Vander Weele CM
Year: 2018
Journal: Nature
Title: Dopamine enhances signal-to-noise ratio in cortical-brainstem encoding of aversive stimuli.
Volume: 563
Issue: 7731
Pages: 397-401
Publication
First Author: Bhat S
Year: 2019
Journal: Circ Heart Fail
Title: Recruitment of RNA Polymerase II to Metabolic Gene Promoters Is Inhibited in the Failing Heart Possibly Through PGC-1α (Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α) Dysregulation.
Volume: 12
Issue: 3
Pages: e005529
Publication
First Author: Kim J
Year: 2023
Journal: Sci Adv
Title: Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction.
Volume: 9
Issue: 47
Pages: eadi8454
Publication
First Author: Liu B
Year: 2022
Journal: Cell
Title: Large-scale multiplexed mosaic CRISPR perturbation in the whole organism.
Volume: 185
Issue: 16
Pages: 3008-3024.e16
Publication  
First Author: Löffler MC
Year: 2018
Journal: EMBO J
Title: Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity.
Volume: 37
Issue: 22
Publication  
First Author: Werner F
Year: 2023
Journal: JCI Insight
Title: Ablation of C-type natriuretic peptide/cGMP signaling in fibroblasts exacerbates adverse cardiac remodeling in mice.
Volume: 8
Issue: 13
Publication
First Author: Song H
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Sickle Cell Anemia Mediates Carotid Artery Expansive Remodeling That Can Be Prevented by Inhibition of JNK (c-Jun N-Terminal Kinase).
Volume: 40
Issue: 5
Pages: 1220-1230
Publication
First Author: Park SY
Year: 2020
Journal: Blood
Title: Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion.
Volume: 135
Issue: 23
Pages: 2071-2084
Publication  
First Author: Magalhães-Gomes MPS
Year: 2018
Journal: Neurochem Int
Title: Fast and slow-twitching muscles are differentially affected by reduced cholinergic transmission in mice deficient for VAChT: A mouse model for congenital myasthenia.
Volume: 120
Pages: 1-12
Publication
First Author: Busskamp V
Year: 2014
Journal: Neuron
Title: miRNAs 182 and 183 are necessary to maintain adult cone photoreceptor outer segments and visual function.
Volume: 83
Issue: 3
Pages: 586-600
Publication
First Author: Christodoulou C
Year: 2020
Journal: Nature
Title: Live-animal imaging of native haematopoietic stem and progenitor cells.
Volume: 578
Issue: 7794
Pages: 278-283
Publication
First Author: Gasperini C
Year: 2023
Journal: EMBO Rep
Title: Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus.
Volume: 24
Issue: 2
Pages: e53801
Publication
First Author: Shao L
Year: 2018
Journal: Nat Commun
Title: The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow.
Volume: 9
Issue: 1
Pages: 2377
Publication  
First Author: Lanaspa MA
Year: 2013
Journal: Nat Commun
Title: Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome.
Volume: 4
Pages: 2434
Publication
First Author: Ishimoto T
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice.
Volume: 109
Issue: 11
Pages: 4320-5
Publication
First Author: Chen M
Year: 2011
Journal: Cancer Cell
Title: Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression.
Volume: 20
Issue: 2
Pages: 173-86
Publication
First Author: Lee MJ
Year: 2009
Journal: PLoS One
Title: Longitudinal evaluation of an N-ethyl-N-nitrosourea-created murine model with normal pressure hydrocephalus.
Volume: 4
Issue: 11
Pages: e7868
Publication
First Author: Chen X
Year: 2020
Journal: Gastroenterology
Title: Clostridioides difficile Toxin A Remodels Membranes and Mediates DNA Entry Into Cells to Activate Toll-Like Receptor 9 Signaling.
Volume: 159
Issue: 6
Pages: 2181-2192.e1
Publication  
First Author: Pfeffer T
Year: 2023
Journal: Antioxidants (Basel)
Title: Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet.
Volume: 12
Issue: 6
Publication  
First Author: Weigand T
Year: 2020
Journal: Int J Mol Sci
Title: A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice.
Volume: 21
Issue: 14
Publication
First Author: Nguyen TA
Year: 2017
Journal: Immunity
Title: SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition.
Volume: 47
Issue: 3
Pages: 498-509.e6
Publication
First Author: Albu S
Year: 2014
Journal: J Sleep Res
Title: Deficiency of FK506-binding protein (FKBP) 51 alters sleep architecture and recovery sleep responses to stress in mice.
Volume: 23
Issue: 2
Pages: 176-85
Publication
First Author: Morini E
Year: 2019
Journal: Am J Hum Genet
Title: ELP1 Splicing Correction Reverses Proprioceptive Sensory Loss in Familial Dysautonomia.
Volume: 104
Issue: 4
Pages: 638-650
Publication
First Author: McIlwain DR
Year: 2012
Journal: Science
Title: iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.
Volume: 335
Issue: 6065
Pages: 229-32
Publication
First Author: Kowalczyk MS
Year: 2012
Journal: Mamm Genome
Title: Nprl3 is required for normal development of the cardiovascular system.
Volume: 23
Issue: 7-8
Pages: 404-15
Publication
First Author: Croon M
Year: 2022
Journal: Sci Adv
Title: FGF21 modulates mitochondrial stress response in cardiomyocytes only under mild mitochondrial dysfunction.
Volume: 8
Issue: 14
Pages: eabn7105
Publication
First Author: Fu Y
Year: 2024
Journal: Nat Commun
Title: Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis.
Volume: 15
Issue: 1
Pages: 2974
Publication  
First Author: Sun S
Year: 2015
Journal: Nat Commun
Title: ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.
Volume: 6
Pages: 6171
Publication
First Author: Santos MCFD
Year: 2020
Journal: Nat Commun
Title: Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.
Volume: 11
Issue: 1
Pages: 296
Publication
First Author: Peterson LW
Year: 2017
Journal: J Exp Med
Title: RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense.
Volume: 214
Issue: 11
Pages: 3171-3182
Publication
First Author: Yeo JC
Year: 2014
Journal: Cell Stem Cell
Title: Klf2 is an essential factor that sustains ground state pluripotency.
Volume: 14
Issue: 6
Pages: 864-72
Publication
First Author: Chua YL
Year: 2016
Journal: J Immunol
Title: Blomia tropicalis-Specific TCR Transgenic Th2 Cells Induce Inducible BALT and Severe Asthma in Mice by an IL-4/IL-13-Dependent Mechanism.
Volume: 197
Issue: 10
Pages: 3771-3781
Publication
First Author: Lewis W
Year: 2007
Journal: Lab Invest
Title: Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase gamma.
Volume: 87
Issue: 4
Pages: 326-35
Publication
First Author: Sarzi E
Year: 2016
Journal: Hum Mol Genet
Title: Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy.
Volume: 25
Issue: 12
Pages: 2539-2551
Publication
First Author: Shorter JR
Year: 2017
Journal: Genetics
Title: Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross.
Volume: 206
Issue: 2
Pages: 557-572
Publication  
First Author: Varshney S
Year: 2024
Journal: Endocrinology
Title: The LEAP2 Response to Cancer-Related Anorexia-Cachexia Syndrome in Male Mice and Patients.
Volume: 165
Issue: 11
Publication
First Author: Nuber S
Year: 2021
Journal: Ann Neurol
Title: A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein Mice.
Volume: 89
Issue: 1
Pages: 74-90
Publication
First Author: Chevalier E
Year: 2012
Journal: Eur Respir J
Title: Lack of involvement of type 7 phosphodiesterase in an experimental model of asthma.
Volume: 39
Issue: 3
Pages: 582-8
Publication
First Author: Greene C
Year: 2022
Journal: Nat Commun
Title: Microvascular stabilization via blood-brain barrier regulation prevents seizure activity.
Volume: 13
Issue: 1
Pages: 2003
Publication
First Author: van Ouwerkerk AF
Year: 2022
Journal: Circulation
Title: Patient-Specific TBX5-G125R Variant Induces Profound Transcriptional Deregulation and Atrial Dysfunction.
Volume: 145
Issue: 8
Pages: 606-619
Publication
First Author: Bauer CS
Year: 2022
Journal: Acta Neuropathol
Title: An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD.
Volume: 144
Issue: 3
Pages: 437-464
Publication
First Author: Feighner SD
Year: 1998
Journal: Mol Endocrinol
Title: Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues.
Volume: 12
Issue: 1
Pages: 137-45
Publication
First Author: Zender L
Year: 2008
Journal: Cell
Title: An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer.
Volume: 135
Issue: 5
Pages: 852-64
Publication
First Author: Beraldo FH
Year: 2011
Journal: FASEB J
Title: Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain.
Volume: 25
Issue: 1
Pages: 265-79
Publication
First Author: Andersen JN
Year: 2010
Journal: Sci Transl Med
Title: Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors.
Volume: 2
Issue: 43
Pages: 43ra55
Publication
First Author: Liakouli V
Year: 2018
Journal: Ann Rheum Dis
Title: Scleroderma fibroblasts suppress angiogenesis via TGF-β/caveolin-1 dependent secretion of pigment epithelium-derived factor.
Volume: 77
Issue: 3
Pages: 431-440
Publication  
First Author: Farcas AM
Year: 2012
Journal: Elife
Title: KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands.
Volume: 1
Pages: e00205
Publication
First Author: Tang X
Year: 2013
Journal: Am J Pathol
Title: Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis.
Volume: 183
Issue: 2
Pages: 470-9
Publication
First Author: Naguib A
Year: 2015
Journal: Mol Cell
Title: PTEN functions by recruitment to cytoplasmic vesicles.
Volume: 58
Issue: 2
Pages: 255-68
Publication
First Author: Soucheray M
Year: 2015
Journal: Cancer Res
Title: Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition.
Volume: 75
Issue: 20
Pages: 4372-83
Publication
First Author: Hasnain SZ
Year: 2014
Journal: Nat Med
Title: Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress.
Volume: 20
Issue: 12
Pages: 1417-26
Publication
First Author: Jennis M
Year: 2016
Journal: Genes Dev
Title: An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model.
Volume: 30
Issue: 8
Pages: 918-30
Publication  
First Author: Choi YJ
Year: 2017
Journal: Science
Title: Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells.
Volume: 355
Issue: 6325
Publication
First Author: Bachofner M
Year: 2017
Journal: Dev Cell
Title: Large-Scale Quantitative Proteomics Identifies the Ubiquitin Ligase Nedd4-1 as an Essential Regulator of Liver Regeneration.
Volume: 42
Issue: 6
Pages: 616-625.e8
Publication
First Author: Azarov I
Year: 2016
Journal: Sci Transl Med
Title: Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning.
Volume: 8
Issue: 368
Pages: 368ra173
Publication
First Author: Chung J
Year: 2015
Journal: Sci Signal
Title: The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability.
Volume: 8
Issue: 372
Pages: ra34
Publication
First Author: Wilson NK
Year: 2015
Journal: Cell Stem Cell
Title: Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations.
Volume: 16
Issue: 6
Pages: 712-24
Publication  
First Author: Krishn SR
Year: 2019
Journal: Matrix Biol
Title: Prostate cancer sheds the αvβ3 integrin in vivo through exosomes.
Volume: 77
Pages: 41-57
Publication    
First Author: Sirey TM
Year: 2019
Journal: Elife
Title: The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity.
Volume: 8
Publication
First Author: Li H
Year: 2020
Journal: Nat Commun
Title: Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging.
Volume: 11
Issue: 1
Pages: 5699
Publication    
First Author: Gnanapradeepan K
Year: 2020
Journal: Elife
Title: Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser.
Volume: 9
Publication
First Author: Sheng YH
Year: 2019
Journal: Oncogene
Title: MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity.
Volume: 38
Issue: 48
Pages: 7294-7310
Publication
First Author: Marshall JL
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes.
Volume: 117
Issue: 52
Pages: 33404-33413
Publication  
First Author: Snijders AM
Year: 2016
Journal: Nat Microbiol
Title: Influence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome.
Volume: 2
Pages: 16221
Publication
First Author: Chung Nien Chin S
Year: 2020
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Coordinate expression loss of GKN1 and GKN2 in gastric cancer via impairment of a glucocorticoid-responsive enhancer.
Volume: 319
Issue: 2
Pages: G175-G188
Publication
First Author: Saito T
Year: 2019
Journal: J Clin Invest
Title: An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia.
Volume: 129
Issue: 2
Pages: 802-819
Publication
First Author: De Salvo C
Year: 2021
Journal: Gastroenterology
Title: Interleukin 33 Triggers Early Eosinophil-Dependent Events Leading to Metaplasia in a Chronic Model of Gastritis-Prone Mice.
Volume: 160
Issue: 1
Pages: 302-316.e7
Publication  
First Author: Karyka E
Year: 2022
Journal: Life Sci Alliance
Title: SMN-deficient cells exhibit increased ribosomal DNA damage.
Volume: 5
Issue: 8
Publication  
First Author: Zaloszyc A
Year: 2022
Journal: Int J Mol Sci
Title: Inactivation of Osteoblast PKC Signaling Reduces Cortical Bone Mass and Density and Aggravates Renal Osteodystrophy in Mice with Chronic Kidney Disease on High Phosphate Diet.
Volume: 23
Issue: 12
Publication
First Author: Yun J
Year: 2023
Journal: Nat Commun
Title: Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling.
Volume: 14
Issue: 1
Pages: 156
Publication
First Author: D'Rozario J
Year: 2023
Journal: Eur J Immunol
Title: Fibroblastic reticular cells provide a supportive niche for lymph node-resident macrophages.
Volume: 53
Issue: 9
Pages: e2250355
Publication
First Author: Zhu Q
Year: 2023
Journal: Signal Transduct Target Ther
Title: OTUB1 promotes osteoblastic bone formation through stabilizing FGFR2.
Volume: 8
Issue: 1
Pages: 142
Publication  
First Author: Zhang Q
Year: 2017
Journal: Sci Immunol
Title: LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes.
Volume: 2
Issue: 9
Publication
First Author: Garey CE
Year: 1994
Journal: Nat Genet
Title: Ceruloplasmin gene defect associated with epilepsy in EL mice.
Volume: 6
Issue: 4
Pages: 426-31
Publication
First Author: Shishodia S
Year: 1998
Journal: Immunol Lett
Title: Protein kinase C: a potential pathway of macrophage activation with cisplatin.
Volume: 61
Issue: 2-3
Pages: 179-86
Publication  
First Author: Hart MC
Year: 2000
Journal: BMC Genomics
Title: Mapping of the mouse actin capping protein beta subunit gene.
Volume: 1
Pages: 1
Publication
First Author: Billet O
Year: 1995
Journal: J Virol
Title: In vivo activity of the hepatitis B virus core promoter: tissue specificity and temporal regulation.
Volume: 69
Issue: 9
Pages: 5912-6
Publication
First Author: Pazzagli L
Year: 1999
Journal: J Biol Chem
Title: Purification, characterization, and amino acid sequence of cerato-platanin, a new phytotoxic protein from Ceratocystis fimbriata f. sp. platani.
Volume: 274
Issue: 35
Pages: 24959-64
Publication
First Author: Sbrana F
Year: 2007
Journal: Eur Biophys J
Title: Atomic force microscopy images suggest aggregation mechanism in cerato-platanin.
Volume: 36
Issue: 7
Pages: 727-32
Publication
First Author: Carresi L
Year: 2006
Journal: Protein Expr Purif
Title: Cerato-platanin, a phytotoxic protein from Ceratocystis fimbriata: expression in Pichia pastoris, purification and characterization.
Volume: 49
Issue: 2
Pages: 159-67
Publication
First Author: Kusmierczyk AR
Year: 2011
Journal: Nat Struct Mol Biol
Title: A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding.
Volume: 18
Issue: 5
Pages: 622-9
Publication
First Author: Matias AC
Year: 2010
Journal: Biochem Soc Trans
Title: Chaperone-assisted assembly of the proteasome core particle.
Volume: 38
Issue: Pt 1
Pages: 29-33
Publication
First Author: Murata S
Year: 2009
Journal: Nat Rev Mol Cell Biol
Title: Molecular mechanisms of proteasome assembly.
Volume: 10
Issue: 2
Pages: 104-15
Publication
First Author: Ksander BR
Year: 2014
Journal: Nature
Title: ABCB5 is a limbal stem cell gene required for corneal development and repair.
Volume: 511
Issue: 7509
Pages: 353-7
Publication
First Author: Parry DA
Year: 2009
Journal: Am J Hum Genet
Title: Loss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice.
Volume: 84
Issue: 5
Pages: 683-91
Publication
First Author: Gulbins E
Year: 2013
Journal: Nat Med
Title: Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs.
Volume: 19
Issue: 7
Pages: 934-8
Publication
First Author: Coppieters F
Year: 2016
Journal: Am J Hum Genet
Title: Isolated and Syndromic Retinal Dystrophy Caused by Biallelic Mutations in RCBTB1, a Gene Implicated in Ubiquitination.
Volume: 99
Issue: 2
Pages: 470-80
Publication
First Author: Meunier I
Year: 2016
Journal: Hum Mol Genet
Title: A dominant mutation in MAPKAPK3, an actor of p38 signaling pathway, causes a new retinal dystrophy involving Bruch's membrane and retinal pigment epithelium.
Volume: 25
Issue: 5
Pages: 916-26
Publication
First Author: Nogusa S
Year: 2016
Journal: Cell Host Microbe
Title: RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.
Volume: 20
Issue: 1
Pages: 13-24
Publication
First Author: Kolakowski LF Jr
Year: 1998
Journal: J Neurochem
Title: Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3.
Volume: 71
Issue: 6
Pages: 2239-51
Publication
First Author: Howard SR
Year: 2016
Journal: EMBO Mol Med
Title: IGSF10 mutations dysregulate gonadotropin-releasing hormone neuronal migration resulting in delayed puberty.
Volume: 8
Issue: 6
Pages: 626-42
Publication
First Author: Beauchemin N
Year: 1999
Journal: Exp Cell Res
Title: Redefined nomenclature for members of the carcinoembryonic antigen family.
Volume: 252
Issue: 2
Pages: 243-9