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Search results 1 to 1 out of 1 for Dnajb12

Category restricted to ProteinDomain (x)

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Categories

Category: ProteinDomain
Type Details Score
Protein Domain
Type: Family
Description: This family contains protein-histidine N-methyltransferases (also known as DORA reverse strand protein DREV) that specifically catalyse 1-methylhistidine (pros-methylhistidine) methylation of target proteins, such as S100A9, NDUFB3, SLC39A5, SLC39A7, ARMC6 and DNAJB12 [, ]. They mediate methylation of proteins with a His-x-His (HxH) motif (where 'x' is preferably a small amino acid), in which the 1-methylhistidine modification may affect the binding of zinc and other metals []. These proteins constitute the main methyltransferase for the 1-methylhistidine modification in cell [].