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Search results 1001 to 1100 out of 1157 for Dct

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Type Details Score
Genotype
Genotype
Symbol: Adamts9/Adamts9<+> Tg(Dct-lacZ)A12Jkn/?
Background: involves: C3HeB/FeJ * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Bcl2/Bcl2 Tg(Dct-lacZ)A12Jkn/?
Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Fscn1/Fscn1 Tg(Dct-lacZ)A12Jkn/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Fscn1/Fscn1<+> Tg(Dct-lacZ)A12Jkn/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Dct/Dct<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Protein Coding Gene
MGI:97492 | Pax8
Type: protein_coding_gene
Organism: mouse, laboratory
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•
Protein Coding Gene
MGI:102564 | Pou3f3
Type: protein_coding_gene
Organism: mouse, laboratory
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•
Publication
31591386 | J:335289
First Author: de Jel MM
Year: 2019
Journal: Oncogenesis
Title: Loss of CYLD accelerates melanoma development and progression in the Tg(Grm1) melanoma mouse model.
Volume: 8
Issue: 10
Pages: 56
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Publication
35293595 | J:335159
 
First Author: Schott M
Year: 2022
Journal: Int J Mol Med
Title: Impact of CYLD on chromatin structure and histone methylation in malignant melanoma.
Volume: 49
Issue: 5
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Strain
MGI:6148716 | B6.Cg-Tg(Dct-lacZ)A12Jkn Tg(Mt1-RET)304Ina/Rbrc
Attribute String: mutant strain, congenic, transgenic
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Publication
25075639 | J:216192
First Author: Lindsay CR
Year: 2015
Journal: J Invest Dermatol
Title: A Rac1-independent role for P-Rex1 in melanoblasts.
Volume: 135
Issue: 1
Pages: 314-318
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•
•
Publication
23557358 | J:265850
First Author: Smith J
Year: 2013
Journal: Pigment Cell Melanoma Res
Title: Chk1 is essential for the development of murine epidermal melanocytes.
Volume: 26
Issue: 4
Pages: 580-5
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Strain
MGI:6353274 | B6.Cg-Ednrb<tm1Ywa> Tg(DBH-Ednrb)1Ywa Tg(Dct-lacZ)A12Jkn/Ywa
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:6148714 | B6.Cg-Tg(Dct-lacZ)A12Jkn Tg(Mt1-RET)242Ina/Rbrc
Attribute String: mutant strain, congenic, transgenic
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Genotype
Genotype
Symbol: Adamts20/Adamts20 Tg(Dct-lacZ)A12Jkn/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gli3/Gli3<+> Tg(Dct-lacZ)A12Jkn/?
Background: involves: BALB/cJ * C57BL/6 * C57BL/6J * CBA
Zygosity: cx
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Gli3/Gli3 Tg(Dct-lacZ)A12Jkn/?
Background: involves: BALB/cJ * C57BL/6 * C57BL/6J * CBA
Zygosity: cx
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Adam10/Adam10<+> Hr
/Hr
Tg(Dct-lacZ)A12Jkn/?
Background: involves: C3HeB/FeJ * C57BL/6 * CBA * HRA/SkhKcl
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Chek1/Chek1 Tg(Dct-lacZ)A12Jkn/? Tg(Tyr-cre)1Lru/?
Background: involves: C57BL/6 * CBA * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Chek1/Chek1<+> Tg(Dct-lacZ)A12Jkn/? Tg(Tyr-cre)1Lru/?
Background: involves: C57BL/6 * CBA * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
12704387 | J:83183
First Author: Pollock PM
Year: 2003
Journal: Nat Genet
Title: Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.
Volume: 34
Issue: 1
Pages: 108-12
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•
•
•
Publication
26121214 | J:226341
First Author: Mairhofer DG
Year: 2015
Journal: J Invest Dermatol
Title: Impaired gp100-Specific CD8(+) T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma Model.
Volume: 135
Issue: 11
Pages: 2785-2793
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Publication
18463680 | J:148139
First Author: Aubin-Houzelstein G
Year: 2008
Journal: J Invest Dermatol
Title: Melanoblasts' proper location and timed differentiation depend on Notch/RBP-J signaling in postnatal hair follicles.
Volume: 128
Issue: 11
Pages: 2686-95
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Publication
19351821 | J:147731
First Author: Anderson PD
Year: 2009
Journal: Cancer Res
Title: The role of the mouse y chromosome on susceptibility to testicular germ cell tumors.
Volume: 69
Issue: 8
Pages: 3614-8
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Publication
21248750 | J:172414
First Author: Zaidi MR
Year: 2011
Journal: Nature
Title: Interferon-γ links ultraviolet radiation to melanomagenesis in mice.
Volume: 469
Issue: 7331
Pages: 548-53
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Publication
29723194 | J:262046
First Author: Harris ML
Year: 2018
Journal: PLoS Biol
Title: A direct link between MITF, innate immunity, and hair graying.
Volume: 16
Issue: 5
Pages: e2003648
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Publication
34010639 | J:307116
First Author: Ostojić J
Year: 2021
Journal: Cell Rep
Title: Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways.
Volume: 35
Issue: 7
Pages: 109136
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Publication
28263969 | J:243371
First Author: Yang H
Year: 2017
Journal: Oncogene
Title: Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma.
Volume: 36
Issue: 27
Pages: 3842-3851
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Publication
26440048 | J:228892
First Author: Koludrovic D
Year: 2015
Journal: PLoS Genet
Title: Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.
Volume: 11
Issue: 10
Pages: e1005555
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Publication
10963668 | J:189356
First Author: Dunn KJ
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development.
Volume: 97
Issue: 18
Pages: 10050-5
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Publication
22570637 | J:185128
First Author: Li J
Year: 2012
Journal: PLoS Genet
Title: YY1 regulates melanocyte development and function by cooperating with MITF.
Volume: 8
Issue: 5
Pages: e1002688
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Publication
22109529 | J:220933
 
First Author: Lindsay CR
Year: 2011
Journal: Nat Commun
Title: P-Rex1 is required for efficient melanoblast migration and melanoma metastasis.
Volume: 2
Pages: 555
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Publication
18037901 | J:135502
First Author: Langton AK
Year: 2008
Journal: J Invest Dermatol
Title: An extended epidermal response heals cutaneous wounds in the absence of a hair follicle stem cell contribution.
Volume: 128
Issue: 5
Pages: 1311-8
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Genotype
Genotype
Symbol: Rpl27a/Rpl27a<+> Tg(Dct-lacZ)#Ove/?
Background: involves: C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Zeb2/Zeb2 Tg(Dct-lacZ)A12Jkn/? Tg(Tyr-cre)1Lru/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Yy1/Yy1 Tg(Dct-lacZ)A12Jkn/? Tg(Tyr-cre)1Lru/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA * DBA/2
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Protein Coding Gene
MGI:97486 | Pax2
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Publication
16964266 | J:113094
First Author: Lalioti MD
Year: 2006
Journal: Nat Genet
Title: Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule.
Volume: 38
Issue: 10
Pages: 1124-32
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•
•
•
Publication
34483955 | J:311473
 
First Author: Milano S
Year: 2021
Journal: Front Physiol
Title: Activation of the Thiazide-Sensitive Sodium-Chloride Cotransporter by Beta3-Adrenoreceptor in the Distal Convoluted Tubule.
Volume: 12
Pages: 695824
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Publication
25565204 | J:219977
First Author: Terker AS
Year: 2015
Journal: Cell Metab
Title: Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride.
Volume: 21
Issue: 1
Pages: 39-50
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Publication
9756992 | J:50681
First Author: April CS
Year: 1998
Journal: Gene
Title: Molecular cloning and sequence analysis of a chicken cDNA encoding tyrosinase-related protein-2/DOPAchrome tautomerase.
Volume: 219
Issue: 1-2
Pages: 45-53
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Publication
16651378 | J:111228
First Author: Moriyama M
Year: 2006
Journal: J Cell Biol
Title: Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells.
Volume: 173
Issue: 3
Pages: 333-9
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Strain
MGI:5702880 | C3FeJ.Cg-Gt(ROSA)26Sor<tm1(GNAQ*)Cvrk> Tg(Dct-lacZ)A12Jkn Tg(Mitf-cre)7114Gsb/Cvrk
Attribute String: transgenic, targeted mutation, mutant strain, congenic
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Publication
31331318 | J:285109
First Author: Mattaini KR
Year: 2019
Journal: BMC Cancer
Title: Increased PHGDH expression promotes aberrant melanin accumulation.
Volume: 19
Issue: 1
Pages: 723
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•
Publication
31138602 | J:279045
First Author: Kircher DA
Year: 2019
Journal: Mol Cancer Res
Title: AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis.
Volume: 17
Issue: 9
Pages: 1787-1800
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Publication
31048499 | J:276334
First Author: Yoo JH
Year: 2019
Journal: Cancer Res
Title: The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.
Volume: 79
Issue: 11
Pages: 2892-2908
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Publication
30787016 | J:274226
First Author: Fischer GM
Year: 2019
Journal: Cancer Discov
Title: Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases.
Volume: 9
Issue: 5
Pages: 628-645
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Publication
26565903 | J:228953
First Author: Cho JH
Year: 2015
Journal: Cell Rep
Title: AKT1 Activation Promotes Development of Melanoma Metastases.
Volume: 13
Issue: 5
Pages: 898-905
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•
Publication
19524511 | J:157347
First Author: Inomata K
Year: 2009
Journal: Cell
Title: Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation.
Volume: 137
Issue: 6
Pages: 1088-99
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Strain
MGI:6272343 | B6.Cg-Ctnnb1<tm2Kem> Tg(Tyr-cre)1Lru Tg(Dct-lacZ)A12Jkn
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
26307673 | J:224977
 
First Author: Conde-Perez A
Year: 2015
Journal: Nat Commun
Title: A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity.
Volume: 6
Pages: 8093
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Publication
24975581 | J:219249
First Author: Wolnicka-Glubisz A
Year: 2015
Journal: Int J Cancer
Title: A melanin-independent interaction between Mc1r and Met signaling pathways is required for HGF-dependent melanoma.
Volume: 136
Issue: 4
Pages: 752-60
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Publication
11976685 | J:130556
First Author: Nishimura EK
Year: 2002
Journal: Nature
Title: Dominant role of the niche in melanocyte stem-cell fate determination.
Volume: 416
Issue: 6883
Pages: 854-60
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Genotype
Genotype
Symbol: Raph1/Raph1 Tmem163/? Tg(Dct-lacZ)A12Jkn/Tg(Dct-lacZ)A12Jkn
Background: involves: C57BL/6 * C57BL/6NTac * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Dct-lacZ)A12Jkn/? Tg(Mitf-cre)7114Gsb/?
Background: C3FeJ.Cg-Gt(ROSA)26Sor Tg(Dct-lacZ)A12Jkn Tg(Mitf-cre)7114Gsb/Cvrk
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Dct/Dct Tgfbr2/Tgfbr2 Tg(Dct-lacZ)A12Jkn/?
Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Rest/Rest H2az2/H2az2<+> Tg(Dct-lacZ)A12Jkn/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Rest/Rest<+> H2az2/H2az2<+> Tg(Dct-lacZ)A12Jkn/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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•
•
•
•
Genotype
Genotype
Symbol: Mc1r/Mc1r Tg(CMV-cre)1Cgn/? Tg(Dct-lacZ)#Ove/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Dct-lacZ)A12Jkn/? Tg(Tyr-cre)1Lru/?
Background: B6.Cg-Ctnnb1 Tg(Tyr-cre)1Lru Tg(Dct-lacZ)A12Jkn
Zygosity: cn
Has Mutant Allele: true
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Publication
19307729 | J:149606
First Author: Glaudemans B
Year: 2009
Journal: J Clin Invest
Title: A missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia.
Volume: 119
Issue: 4
Pages: 936-42
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Publication
24610784 | J:209614
First Author: Richards J
Year: 2014
Journal: J Biol Chem
Title: A role for the circadian clock protein Per1 in the regulation of the NaCl co-transporter (NCC) and the with-no-lysine kinase (WNK) cascade in mouse distal convoluted tubule cells.
Volume: 289
Issue: 17
Pages: 11791-806
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Publication
21216955 | J:171162
First Author: Fu Y
Year: 2011
Journal: J Biol Chem
Title: Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo.
Volume: 286
Issue: 14
Pages: 12617-26
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Publication
27349617 | J:236099
 
First Author: de Baaij JH
Year: 2016
Journal: Sci Rep
Title: Identification of SLC41A3 as a novel player in magnesium homeostasis.
Volume: 6
Pages: 28565
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Publication
28052988 | J:287780
First Author: Cuevas CA
Year: 2017
Journal: J Am Soc Nephrol
Title: Potassium Sensing by Renal Distal Tubules Requires Kir4.1.
Volume: 28
Issue: 6
Pages: 1814-1825
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Publication
31736353 | J:294764
First Author: Thomson MN
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia.
Volume: 318
Issue: 1
Pages: F216-F228
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Publication
29897283 | J:281038
First Author: Wang MX
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Kir5.1 regulates Nedd4-2-mediated ubiquitination of Kir4.1 in distal nephron.
Volume: 315
Issue: 4
Pages: F986-F996
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Publication
25071208 | J:213940
First Author: Zhang C
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: KCNJ10 determines the expression of the apical Na-Cl cotransporter (NCC) in the early distal convoluted tubule (DCT1).
Volume: 111
Issue: 32
Pages: 11864-9
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Publication
25848073 | J:322093
First Author: Wang L
Year: 2015
Journal: J Am Soc Nephrol
Title: Caveolin-1 Deficiency Inhibits the Basolateral K+ Channels in the Distal Convoluted Tubule and Impairs Renal K+ and Mg2+ Transport.
Volume: 26
Issue: 11
Pages: 2678-90
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Publication
22674026 | J:188431
First Author: Armour EA
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.
Volume: 303
Issue: 4
Pages: F584-92
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Publication
21633011 | J:173309
First Author: Paulais M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome.
Volume: 108
Issue: 25
Pages: 10361-6
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Publication
29667910 | J:281418
First Author: Wu P
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule.
Volume: 315
Issue: 2
Pages: F223-F230
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Publication
29384416 | J:281911
First Author: Yang YS
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Differential roles of WNK4 in regulation of NCC in vivo.
Volume: 314
Issue: 5
Pages: F999-F1007
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Publication
24655003 | J:241978
 
First Author: Takahashi D
Year: 2014
Journal: Biosci Rep
Title: WNK4 is the major WNK positively regulating NCC in the mouse kidney.
Volume: 34
Issue: 3
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Publication
12925696 | J:85156
First Author: Rubera I
Year: 2003
Journal: J Clin Invest
Title: Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance.
Volume: 112
Issue: 4
Pages: 554-65
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Publication
22759396 | J:188407
First Author: Markadieu N
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: A primary culture of distal convoluted tubules expressing functional thiazide-sensitive NaCl transport.
Volume: 303
Issue: 6
Pages: F886-92
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Publication
24231659 | J:294870
First Author: Picard N
Year: 2014
Journal: J Am Soc Nephrol
Title: Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension.
Volume: 25
Issue: 3
Pages: 511-22
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Publication
30007527 | J:286774
First Author: Tokonami N
Year: 2018
Journal: Kidney Int
Title: Uromodulin is expressed in the distal convoluted tubule, where it is critical for regulation of the sodium chloride cotransporter NCC.
Volume: 94
Issue: 4
Pages: 701-715
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Publication
22791335 | J:188533
First Author: Cheng CJ
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Kidney-specific WNK1 inhibits sodium reabsorption in the cortical thick ascending limb.
Volume: 303
Issue: 5
Pages: F667-73
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Publication
29237822 | J:290557
First Author: Boyd-Shiwarski CR
Year: 2018
Journal: Mol Biol Cell
Title: Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent.
Volume: 29
Issue: 4
Pages: 499-509
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Publication
25477470 | J:237441
First Author: Cheng CJ
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: STE20/SPS1-related proline/alanine-rich kinase (SPAK) is critical for sodium reabsorption in isolated, perfused thick ascending limb.
Volume: 308
Issue: 5
Pages: F437-43
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Publication
37989423 | J:343644
First Author: Sarkar H
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Loss of REP1 impacts choroidal melanogenesis and vasculogenesis in choroideremia.
Volume: 1870
Issue: 2
Pages: 166963
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Publication
28442491 | J:287773
First Author: Grimm PR
Year: 2017
Journal: J Am Soc Nephrol
Title: Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules.
Volume: 28
Issue: 9
Pages: 2597-2606
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Publication
23613530 | J:210872
First Author: Gregory FD
Year: 2013
Journal: J Physiol
Title: Harmonin enhances voltage-dependent facilitation of Cav1.3 channels and synchronous exocytosis in mouse inner hair cells.
Volume: 591
Issue: 13
Pages: 3253-69
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Publication
17804801 | J:124879
First Author: Belge H
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Renal expression of parvalbumin is critical for NaCl handling and response to diuretics.
Volume: 104
Issue: 37
Pages: 14849-54
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